DE60320867D1 - Verfahren und vorrichtung zur charakterisierung von analyten - Google Patents

Verfahren und vorrichtung zur charakterisierung von analyten

Info

Publication number
DE60320867D1
DE60320867D1 DE60320867T DE60320867T DE60320867D1 DE 60320867 D1 DE60320867 D1 DE 60320867D1 DE 60320867 T DE60320867 T DE 60320867T DE 60320867 T DE60320867 T DE 60320867T DE 60320867 D1 DE60320867 D1 DE 60320867D1
Authority
DE
Germany
Prior art keywords
amino acid
labeled amino
nanopore
disclosed
acid residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60320867T
Other languages
English (en)
Inventor
Xing Su
Andrew Berlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intel Corp
Original Assignee
Intel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intel Corp filed Critical Intel Corp
Application granted granted Critical
Publication of DE60320867D1 publication Critical patent/DE60320867D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE60320867T 2003-10-29 2003-10-31 Verfahren und vorrichtung zur charakterisierung von analyten Expired - Lifetime DE60320867D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/697,682 US8278055B2 (en) 2002-05-01 2003-10-29 Methods and device for analyte characterization
PCT/US2003/034526 WO2005052591A1 (en) 2003-10-29 2003-10-31 Methods and device for analyte characterization

Publications (1)

Publication Number Publication Date
DE60320867D1 true DE60320867D1 (de) 2008-06-19

Family

ID=34633120

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60320867T Expired - Lifetime DE60320867D1 (de) 2003-10-29 2003-10-31 Verfahren und vorrichtung zur charakterisierung von analyten

Country Status (7)

Country Link
US (1) US8278055B2 (de)
EP (1) EP1685407B1 (de)
CN (2) CN100595589C (de)
AT (1) ATE394680T1 (de)
AU (1) AU2003304573A1 (de)
DE (1) DE60320867D1 (de)
WO (1) WO2005052591A1 (de)

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US9121843B2 (en) 2007-05-08 2015-09-01 Trustees Of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
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US20090069542A1 (en) * 2007-09-12 2009-03-12 Board Of Regents Of The University Of Nebraska Process Of Extracting High Quality Proteins From Cereal Grains And Their ByProducts Using Acidic Medium And A Reducing Agent
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CN102928387B (zh) * 2010-12-31 2014-08-20 清华大学 用于单分子检测的分子载体
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CN102169086B (zh) * 2010-12-31 2013-01-09 清华大学 用于单分子检测的分子载体
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BR112014020255B1 (pt) * 2012-02-16 2022-01-25 The Regents Of The University Of California Aparelho, sistema e método de transporte de proteína através de nanoporo
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US9274430B2 (en) 2012-10-10 2016-03-01 Arizona Board Of Regents On Behalf Of Arizona State University Systems and devices for molecule sensing and method of manufacturing thereof
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
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US9791453B2 (en) 2012-12-26 2017-10-17 International Business Machines Corporation Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels
US10294516B2 (en) 2013-01-18 2019-05-21 Nabsys 2.0 Llc Enhanced probe binding
US9952198B2 (en) 2013-03-05 2018-04-24 Arizona Board Of Regents On Behalf Of Arizona State University Translocation of a polymer through a nanopore
CN105102627B (zh) * 2013-03-15 2018-10-19 纽约哥伦比亚大学理事会 用于检测样品中多种预定化合物的方法
AU2014268322B2 (en) 2013-05-24 2019-01-24 Quantapore, Inc. Nanopore-based nucleic acid analysis with mixed FRET detection
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US10024851B2 (en) * 2013-10-15 2018-07-17 International Business Machines Corporation Use of disulfide bonds to form a reversible and reusable coating for nanofluidic devices
US9303310B2 (en) 2013-10-15 2016-04-05 International Business Machines Corporation Nanofluidic sensor comprising spatially separated functional sensing components
US9255321B2 (en) 2013-10-15 2016-02-09 Globalfoundries Inc. Directed surface functionalization on selected surface areas of topographical features with nanometer resolution
WO2015131073A1 (en) 2014-02-27 2015-09-03 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Triazole-based reader molecules and methods for synthesizing and use thereof
US9988677B1 (en) * 2014-06-10 2018-06-05 Mark Fleharty DNA/RNA sequencing using a semiconducting nanopore
US9921181B2 (en) 2014-06-26 2018-03-20 International Business Machines Corporation Detection of translocation events using graphene-based nanopore assemblies
US20170227520A1 (en) * 2014-07-25 2017-08-10 Mikhail Shchepinov Single Molecule Proteomics
CN107109472B (zh) 2014-10-10 2021-05-11 昆塔波尔公司 利用互相猝灭的荧光标记物的基于纳米孔的聚合物分析
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US10823721B2 (en) 2016-07-05 2020-11-03 Quantapore, Inc. Optically based nanopore sequencing
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TWI636146B (zh) * 2017-06-02 2018-09-21 立得光電科技股份有限公司 Film formation method of functional film layer, functional film layer, and antibacterial anti-fingerprint component
WO2019213456A1 (en) * 2018-05-02 2019-11-07 Cornell University Ultrasmall nanoparticles and methods of making, using and analyzing same
GB201809323D0 (en) 2018-06-06 2018-07-25 Oxford Nanopore Tech Ltd Method
CN112147185B (zh) * 2019-06-29 2022-07-01 清华大学 一种控制多肽穿过纳米孔速度的方法及其应用
CN110646417B (zh) * 2019-10-24 2021-10-15 福建医科大学 以纳米金为显色探针的磷酸吡哆醛快速测定方法
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WO2023140732A1 (en) 2022-01-21 2023-07-27 Technische Universiteit Delft Method for measuring a linearized protein, a 2d material membrane, a nanopore device comprising the 2d material membrane, a system comprising the nanopore device, and a production method for providing the 2d material membrane
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Also Published As

Publication number Publication date
EP1685407B1 (de) 2008-05-07
CN1860370A (zh) 2006-11-08
EP1685407A1 (de) 2006-08-02
CN101846688A (zh) 2010-09-29
CN101846688B (zh) 2014-06-25
CN100595589C (zh) 2010-03-24
AU2003304573A1 (en) 2005-06-17
WO2005052591A1 (en) 2005-06-09
US8278055B2 (en) 2012-10-02
ATE394680T1 (de) 2008-05-15
US20050282229A1 (en) 2005-12-22

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