ATE534909T1 - Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäuren - Google Patents
Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäurenInfo
- Publication number
- ATE534909T1 ATE534909T1 AT05855111T AT05855111T ATE534909T1 AT E534909 T1 ATE534909 T1 AT E534909T1 AT 05855111 T AT05855111 T AT 05855111T AT 05855111 T AT05855111 T AT 05855111T AT E534909 T1 ATE534909 T1 AT E534909T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acids
- natural amino
- proteins
- proteomic profiling
- reagents
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63885604P | 2004-12-22 | 2004-12-22 | |
US66847105P | 2005-04-05 | 2005-04-05 | |
PCT/US2005/046496 WO2006069203A2 (en) | 2004-12-22 | 2005-12-21 | Methods for proteomic profiling using non-natural amino acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE534909T1 true ATE534909T1 (de) | 2011-12-15 |
Family
ID=36602311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05855111T ATE534909T1 (de) | 2004-12-22 | 2005-12-21 | Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäuren |
Country Status (4)
Country | Link |
---|---|
US (3) | US20060216760A1 (de) |
EP (2) | EP1828780B1 (de) |
AT (1) | ATE534909T1 (de) |
WO (1) | WO2006069203A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60233574D1 (de) | 2001-07-10 | 2009-10-15 | Univ R | Verfahren und zusammensetzungen zum nachweis des aktivierungszustands multipler proteine in einzelzellen |
US7381535B2 (en) | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
US7393656B2 (en) * | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
ATE534909T1 (de) | 2004-12-22 | 2011-12-15 | California Inst Of Techn | Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäuren |
CA2624290A1 (en) * | 2005-10-12 | 2007-04-26 | Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
US20100247433A1 (en) * | 2005-10-14 | 2010-09-30 | California Institute Of Technology | Use of non-canonical amino acids as metabolic markers for rapidly-dividing cells |
EP2060584A1 (de) * | 2007-10-16 | 2009-05-20 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zur Herstellung von Proteinen mit chemisch funktionalisierten N-Termini |
WO2012054749A1 (en) | 2010-10-20 | 2012-04-26 | Li-Cor, Inc. | Cyanine dyes and their conjugates |
WO2015128723A1 (en) * | 2014-02-28 | 2015-09-03 | Dh Technologies Development Pte. Ltd. | Microbial identification and quantitation using ms cleavable tags |
WO2018042454A2 (en) * | 2016-09-01 | 2018-03-08 | Translational Health Science And Technology Institute (Thsti) | Method of hyperplexing in mass spectrometry to elucidate temporal dynamics of proteome |
WO2020180800A1 (en) * | 2019-03-04 | 2020-09-10 | The Board Of Trustees Of The Leland Stanford Junior University | Engineered cd47 extracellular domain for bioconjugation |
JP2022552256A (ja) * | 2019-10-15 | 2022-12-15 | ジュニャーナ セラピューティクス インコーポレイテッド | 反応性アフィニティプローブ相互作用探索プラットフォーム |
EP4108672A4 (de) * | 2020-02-17 | 2023-08-16 | Nantong Yichen Biopharma. Co. Ltd. | Antikörper-screening-verfahren |
CN114075588A (zh) * | 2020-07-29 | 2022-02-22 | 中国科学院上海有机化学研究所 | 一种高特异性的细胞分泌蛋白富集方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US6596476B1 (en) * | 1989-12-22 | 2003-07-22 | Abbott Laboratories | Hepatitis C assay |
US6013434A (en) * | 1989-12-22 | 2000-01-11 | Howard Florey Institute Of Experimental Physiology And Medicine | Oligonucleotide-polyamide conjugates |
US5326856A (en) | 1992-04-09 | 1994-07-05 | Cytogen Corporation | Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding |
US5538897A (en) | 1994-03-14 | 1996-07-23 | University Of Washington | Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases |
US5986076A (en) | 1994-05-11 | 1999-11-16 | Trustees Of Boston University | Photocleavable agents and conjugates for the detection and isolation of biomolecules |
WO1996000378A1 (en) | 1994-06-23 | 1996-01-04 | Affymax Technologies N.V. | Photolabile compounds and methods for their use |
US8409564B2 (en) * | 1999-10-05 | 2013-04-02 | Universite De Montreal | Rhodamine derivatives for photodynamic diagnosis and treatment |
ATE329925T1 (de) * | 2000-03-16 | 2006-07-15 | Univ California | Chemoselektive anknüpfung durch verwendung eines phosphins |
US6586207B2 (en) | 2000-05-26 | 2003-07-01 | California Institute Of Technology | Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues |
EP1383802A4 (de) * | 2001-03-30 | 2005-08-03 | Univ California | Anti-muc-1-einzelkettenantikörper zum targeting von tumoren |
EP1490677A4 (de) | 2002-02-27 | 2006-01-18 | California Inst Of Techn | Computerberechnungsverfahren zur konstruktion von enzymen zum einbau von aminosäureanalogen in proteine |
US7449558B2 (en) * | 2003-10-30 | 2008-11-11 | National University Of Singapore | Site-specific labelling of proteins |
US20060057069A1 (en) * | 2004-06-07 | 2006-03-16 | California Institute Of Technology | Detection of protein expression in vivo using fluorescent puromycin conjugates |
EP1766409A2 (de) * | 2004-06-18 | 2007-03-28 | Molecular Probes, Inc. | Fluoreszierende isotop-etiketten und verfahren zu ihrer verwendung |
PT1812031E (pt) * | 2004-11-01 | 2015-10-01 | Univ California | Composições e métodos para modificação de biomoléculas |
ATE534909T1 (de) | 2004-12-22 | 2011-12-15 | California Inst Of Techn | Verfahren zur proteomischen profilierung mithilfe nichtnatürlicher aminosäuren |
-
2005
- 2005-12-21 AT AT05855111T patent/ATE534909T1/de active
- 2005-12-21 WO PCT/US2005/046496 patent/WO2006069203A2/en active Application Filing
- 2005-12-21 US US11/314,323 patent/US20060216760A1/en not_active Abandoned
- 2005-12-21 EP EP05855111A patent/EP1828780B1/de active Active
- 2005-12-21 EP EP10181451.5A patent/EP2290369B1/de active Active
-
2017
- 2017-04-24 US US15/495,414 patent/US20170292958A1/en not_active Abandoned
-
2020
- 2020-10-09 US US17/067,028 patent/US20210223252A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2290369B1 (de) | 2013-08-14 |
WO2006069203A2 (en) | 2006-06-29 |
US20210223252A1 (en) | 2021-07-22 |
US20170292958A1 (en) | 2017-10-12 |
EP2290369A1 (de) | 2011-03-02 |
EP1828780A2 (de) | 2007-09-05 |
EP1828780B1 (de) | 2011-11-23 |
US20060216760A1 (en) | 2006-09-28 |
WO2006069203A3 (en) | 2007-02-22 |
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