DE60318584D1 - Arylimidazolderivate und deren verwendung als no synthase inhibitoren und als modulatoren der na-kanäle - Google Patents
Arylimidazolderivate und deren verwendung als no synthase inhibitoren und als modulatoren der na-kanäleInfo
- Publication number
- DE60318584D1 DE60318584D1 DE60318584T DE60318584T DE60318584D1 DE 60318584 D1 DE60318584 D1 DE 60318584D1 DE 60318584 T DE60318584 T DE 60318584T DE 60318584 T DE60318584 T DE 60318584T DE 60318584 D1 DE60318584 D1 DE 60318584D1
- Authority
- DE
- Germany
- Prior art keywords
- modulators
- channels
- synthase inhibitors
- arylimidazole derivatives
- arylimidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0209416A FR2842808B1 (fr) | 2002-07-25 | 2002-07-25 | Nouveaux derives d'arylimidazoles, leur preparation et leurs applications therapeutiques |
FR0209416 | 2002-07-25 | ||
PCT/FR2003/002336 WO2004011402A2 (fr) | 2002-07-25 | 2003-07-24 | Derives d'arylimidazoles et leur utilisation en tant qu’inhibiteurs de no synthases et en tant que modulateurs des canaux sodiques |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60318584D1 true DE60318584D1 (de) | 2008-02-21 |
DE60318584T2 DE60318584T2 (de) | 2009-01-08 |
Family
ID=30011457
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60318584T Expired - Fee Related DE60318584T2 (de) | 2002-07-25 | 2003-07-24 | Arylimidazolderivate und deren verwendung als no-synthase-inhibitoren und als modulatoren der na-kanäle |
Country Status (19)
Country | Link |
---|---|
US (1) | US7192975B2 (de) |
EP (1) | EP1527068B1 (de) |
JP (1) | JP2005533857A (de) |
CN (1) | CN100340556C (de) |
AR (1) | AR040701A1 (de) |
AT (1) | ATE383354T1 (de) |
AU (1) | AU2003273468B2 (de) |
BR (1) | BR0312289A (de) |
CA (1) | CA2493751A1 (de) |
DE (1) | DE60318584T2 (de) |
ES (1) | ES2299719T3 (de) |
FR (1) | FR2842808B1 (de) |
HR (1) | HRP20041232A2 (de) |
IL (1) | IL165612A0 (de) |
MX (1) | MXPA05000931A (de) |
NZ (1) | NZ537047A (de) |
PL (1) | PL374858A1 (de) |
RU (1) | RU2323216C2 (de) |
WO (1) | WO2004011402A2 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7291641B2 (en) * | 1999-10-11 | 2007-11-06 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments |
NZ567540A (en) * | 2005-12-22 | 2010-07-30 | Newron Pharm Spa | 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators |
CA2843265C (en) | 2010-07-28 | 2019-09-17 | The Regents Of The University Of California | Peripherally restricted faah inhibitors |
EP2744778B1 (de) | 2011-08-19 | 2019-01-16 | The Regents of The University of California | Peripher eingeschränkte faah-hemmer aus meta-substituiertem biphenyl |
DE102011113749A1 (de) * | 2011-09-14 | 2013-03-14 | Aicuris Gmbh & Co. Kg | Sulfonsäuresalze Heterocyclylamid-substituiertr Imidazole |
MX337469B (es) * | 2011-10-26 | 2016-03-02 | Pfizer Ltd | Derivados de (4-fenilimidazol-2-il)etilamina utiles como moduladores de canal de sodio. |
ES2908240T3 (es) | 2014-04-07 | 2022-04-28 | Univ California | Inhibidores de la enzima amida hidrolasa de ácidos grasos (FAAH) con biodisponibilidad oral mejorada y su uso como medicamentos |
FR3097222B1 (fr) * | 2019-06-11 | 2021-05-28 | Michelin & Cie | Nouveaux composes 1,3-dipolaires comprenant un heterocycle aromatique et un cycle imidazole |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1201523B (it) * | 1982-05-18 | 1989-02-02 | Angeli Inst Spa | Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico |
US5807885A (en) * | 1993-08-12 | 1998-09-15 | Astra Aktiebolag | Amidine derivatives with nitric oxide synthetase activities |
FR2764889B1 (fr) * | 1997-06-20 | 2000-09-01 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
TWI283577B (en) * | 1999-10-11 | 2007-07-11 | Sod Conseils Rech Applic | Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof |
-
2002
- 2002-07-25 FR FR0209416A patent/FR2842808B1/fr not_active Expired - Fee Related
-
2003
- 2003-07-24 NZ NZ537047A patent/NZ537047A/en unknown
- 2003-07-24 DE DE60318584T patent/DE60318584T2/de not_active Expired - Fee Related
- 2003-07-24 EP EP03755628A patent/EP1527068B1/de not_active Expired - Lifetime
- 2003-07-24 ES ES03755628T patent/ES2299719T3/es not_active Expired - Lifetime
- 2003-07-24 MX MXPA05000931A patent/MXPA05000931A/es active IP Right Grant
- 2003-07-24 US US10/517,267 patent/US7192975B2/en not_active Expired - Fee Related
- 2003-07-24 RU RU2005105058/04A patent/RU2323216C2/ru not_active IP Right Cessation
- 2003-07-24 AT AT03755628T patent/ATE383354T1/de not_active IP Right Cessation
- 2003-07-24 CA CA002493751A patent/CA2493751A1/fr not_active Abandoned
- 2003-07-24 JP JP2004523872A patent/JP2005533857A/ja active Pending
- 2003-07-24 BR BR0312289-1A patent/BR0312289A/pt not_active IP Right Cessation
- 2003-07-24 WO PCT/FR2003/002336 patent/WO2004011402A2/fr active IP Right Grant
- 2003-07-24 PL PL03374858A patent/PL374858A1/xx unknown
- 2003-07-24 CN CNB038178214A patent/CN100340556C/zh not_active Expired - Fee Related
- 2003-07-24 AU AU2003273468A patent/AU2003273468B2/en not_active Ceased
- 2003-07-25 AR AR20030102689A patent/AR040701A1/es unknown
-
2004
- 2004-12-07 IL IL16561204A patent/IL165612A0/xx unknown
- 2004-12-30 HR HR20041232A patent/HRP20041232A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HRP20041232A2 (en) | 2005-02-28 |
BR0312289A (pt) | 2005-04-12 |
EP1527068A2 (de) | 2005-05-04 |
EP1527068B1 (de) | 2008-01-09 |
AU2003273468B2 (en) | 2008-12-18 |
CA2493751A1 (fr) | 2004-02-05 |
ATE383354T1 (de) | 2008-01-15 |
CN1671701A (zh) | 2005-09-21 |
US7192975B2 (en) | 2007-03-20 |
JP2005533857A (ja) | 2005-11-10 |
FR2842808B1 (fr) | 2004-09-10 |
CN100340556C (zh) | 2007-10-03 |
IL165612A0 (en) | 2006-01-15 |
RU2005105058A (ru) | 2005-07-20 |
PL374858A1 (en) | 2005-11-14 |
US20050234118A1 (en) | 2005-10-20 |
WO2004011402A3 (fr) | 2004-04-29 |
WO2004011402A2 (fr) | 2004-02-05 |
DE60318584T2 (de) | 2009-01-08 |
AU2003273468A1 (en) | 2004-02-16 |
FR2842808A1 (fr) | 2004-01-30 |
AR040701A1 (es) | 2005-04-13 |
ES2299719T3 (es) | 2008-06-01 |
RU2323216C2 (ru) | 2008-04-27 |
MXPA05000931A (es) | 2005-03-23 |
NZ537047A (en) | 2005-08-26 |
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