DE60312723T2 - Herzstimulation zur erweiterung der refraktärzeit des vorhofs - Google Patents
Herzstimulation zur erweiterung der refraktärzeit des vorhofs Download PDFInfo
- Publication number
- DE60312723T2 DE60312723T2 DE60312723T DE60312723T DE60312723T2 DE 60312723 T2 DE60312723 T2 DE 60312723T2 DE 60312723 T DE60312723 T DE 60312723T DE 60312723 T DE60312723 T DE 60312723T DE 60312723 T2 DE60312723 T2 DE 60312723T2
- Authority
- DE
- Germany
- Prior art keywords
- atrial
- pacing
- pulses
- excitation
- stimulating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000638 stimulation Effects 0.000 title claims description 21
- 230000001746 atrial effect Effects 0.000 claims abstract description 126
- 206010003658 Atrial Fibrillation Diseases 0.000 claims abstract description 32
- 210000002837 heart atrium Anatomy 0.000 claims abstract description 21
- 230000036279 refractory period Effects 0.000 claims abstract description 17
- 230000005284 excitation Effects 0.000 claims description 58
- 230000035939 shock Effects 0.000 claims description 28
- 238000005259 measurement Methods 0.000 claims description 20
- 230000037007 arousal Effects 0.000 claims description 18
- 230000004936 stimulating effect Effects 0.000 claims description 18
- 208000001871 Tachycardia Diseases 0.000 claims description 16
- 230000000747 cardiac effect Effects 0.000 claims description 16
- 230000033764 rhythmic process Effects 0.000 claims description 14
- 230000002861 ventricular Effects 0.000 claims description 11
- 208000006218 bradycardia Diseases 0.000 claims description 9
- 230000036471 bradycardia Effects 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 9
- 230000002964 excitative effect Effects 0.000 claims description 7
- 230000006870 function Effects 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 5
- 238000002560 therapeutic procedure Methods 0.000 abstract description 12
- 230000037024 effective refractory period Effects 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 4
- 210000004027 cell Anatomy 0.000 description 12
- 206010061592 cardiac fibrillation Diseases 0.000 description 8
- 230000002600 fibrillogenic effect Effects 0.000 description 8
- 230000028161 membrane depolarization Effects 0.000 description 8
- 102100032381 Alpha-hemoglobin-stabilizing protein Human genes 0.000 description 6
- 101000797984 Homo sapiens Alpha-hemoglobin-stabilizing protein Proteins 0.000 description 6
- 230000036982 action potential Effects 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 230000002159 abnormal effect Effects 0.000 description 4
- 230000002107 myocardial effect Effects 0.000 description 4
- 208000003663 ventricular fibrillation Diseases 0.000 description 4
- 238000013194 cardioversion Methods 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 230000006794 tachycardia Effects 0.000 description 3
- 206010047302 ventricular tachycardia Diseases 0.000 description 3
- 206010003130 Arrhythmia supraventricular Diseases 0.000 description 2
- 206010003662 Atrial flutter Diseases 0.000 description 2
- 206010049447 Tachyarrhythmia Diseases 0.000 description 2
- 206010003119 arrhythmia Diseases 0.000 description 2
- 230000006793 arrhythmia Effects 0.000 description 2
- 230000002457 bidirectional effect Effects 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000002999 depolarising effect Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 230000003834 intracellular effect Effects 0.000 description 2
- 210000005246 left atrium Anatomy 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000000663 muscle cell Anatomy 0.000 description 2
- 210000004165 myocardium Anatomy 0.000 description 2
- 238000002633 shock therapy Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000030990 Impulse-control disease Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010047281 Ventricular arrhythmia Diseases 0.000 description 1
- 206010065341 Ventricular tachyarrhythmia Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 206010003668 atrial tachycardia Diseases 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000000739 chaotic effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 210000003748 coronary sinus Anatomy 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000005279 excitation period Effects 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000034225 regulation of ventricular cardiomyocyte membrane depolarization Effects 0.000 description 1
- 230000002336 repolarization Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000036390 resting membrane potential Effects 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 210000001013 sinoatrial node Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
- A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
- A61N1/39622—Pacing therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
- A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/395—Heart defibrillators for treating atrial fibrillation
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US302747 | 2002-11-22 | ||
| US10/302,747 US7203538B2 (en) | 2002-11-22 | 2002-11-22 | Pacing therapy for extending atrial refractory period |
| PCT/US2003/037155 WO2004047918A1 (en) | 2002-11-22 | 2003-11-20 | Pacing therapy for extending atrial refractory period |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60312723D1 DE60312723D1 (de) | 2007-05-03 |
| DE60312723T2 true DE60312723T2 (de) | 2007-12-06 |
Family
ID=32324865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60312723T Expired - Lifetime DE60312723T2 (de) | 2002-11-22 | 2003-11-20 | Herzstimulation zur erweiterung der refraktärzeit des vorhofs |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7203538B2 (enExample) |
| EP (1) | EP1562676B1 (enExample) |
| JP (1) | JP4594735B2 (enExample) |
| AT (1) | ATE357271T1 (enExample) |
| AU (1) | AU2003291815A1 (enExample) |
| DE (1) | DE60312723T2 (enExample) |
| WO (1) | WO2004047918A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7203538B2 (en) * | 2002-11-22 | 2007-04-10 | Cardiac Pacemakers, Inc. | Pacing therapy for extending atrial refractory period |
| US8175702B2 (en) | 2004-11-04 | 2012-05-08 | The Washington University | Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries |
| US8478406B2 (en) | 2006-04-24 | 2013-07-02 | Medtronic, Inc. | Apparatus and methods of delivering an enhanced refractory period stimulation therapy |
| US8046064B2 (en) * | 2006-04-24 | 2011-10-25 | Medtronic, Inc. | Method of delivering PESP/ICC as well as adjusting the refractory period of the heart |
| US7729763B2 (en) * | 2006-05-18 | 2010-06-01 | Medtronic, Inc. | Post long pause overdrive pacing in response to atrial tachyarrythmia episode |
| US7869867B2 (en) * | 2006-10-27 | 2011-01-11 | Cyberonics, Inc. | Implantable neurostimulator with refractory stimulation |
| US8560066B2 (en) | 2007-12-11 | 2013-10-15 | Washington University | Method and device for three-stage atrial cardioversion therapy |
| US8874208B2 (en) | 2007-12-11 | 2014-10-28 | The Washington University | Methods and devices for three-stage ventricular therapy |
| US8403830B2 (en) | 2010-08-06 | 2013-03-26 | Cardiac Pacemakers, Inc. | Rhythm discrimination enhancement—AV drive |
| US8369938B2 (en) | 2010-08-06 | 2013-02-05 | Cardiac Pacemakers, Inc. | Rhythm discrimination enhancement—chamber of tachy origination |
| US9675806B2 (en) | 2012-10-09 | 2017-06-13 | Medtronic, Inc. | Cardiac pacing during medical procedures |
| US8744572B1 (en) * | 2013-01-31 | 2014-06-03 | Medronic, Inc. | Systems and methods for leadless pacing and shock therapy |
| JP2022553322A (ja) | 2019-10-23 | 2022-12-22 | インパルス ダイナミクス エヌヴイ | 心房性不整脈患者のための心臓収縮性調節 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554922A (en) | 1982-09-30 | 1985-11-26 | Prystowsky Eric N | Method of inhibiting cardiac arrhythmias |
| AU661179B2 (en) | 1992-06-30 | 1995-07-13 | Medtronic, Inc. | Method and apparatus for treatment of angina |
| US5344221A (en) * | 1993-01-27 | 1994-09-06 | Macwilliam Mark W | Anti-theft method and apparatus for locking the brakes of a vehicle |
| JP4175662B2 (ja) * | 1996-01-08 | 2008-11-05 | インパルス ダイナミクス エヌ．ヴイ． | 電気的筋肉制御装置 |
| AU724404B2 (en) * | 1996-01-08 | 2000-09-21 | Impulse Dynamics N.V. | Electrical muscle controller |
| WO1997027797A2 (en) | 1996-02-05 | 1997-08-07 | Shlomo Ben-Haim | Electrical muscle controller |
| US5645569A (en) * | 1996-06-04 | 1997-07-08 | Incontrol, Inc. | Post atrial cardioversion atrial pacing and method |
| EP0811399A3 (en) | 1996-06-04 | 1999-05-12 | INCONTROL, Inc. | Post atrial cardioversion high rate atrial pacing with gradual rate return |
| US5741311A (en) | 1996-06-27 | 1998-04-21 | Medtronic, Inc. | Implantable medical device system with method for determining lead condition |
| DE69918657T2 (de) | 1999-01-28 | 2005-09-08 | Sorin Biomedica Crm S.R.L., Saluggia | Herzstimulationsgerät mit elektrotonischer Blockade |
| US6377852B1 (en) * | 2000-01-20 | 2002-04-23 | Pacesetter, Inc. | Implanatable cardiac stimulation device and method for prolonging atrial refractoriness |
| US7203538B2 (en) * | 2002-11-22 | 2007-04-10 | Cardiac Pacemakers, Inc. | Pacing therapy for extending atrial refractory period |
-
2002
- 2002-11-22 US US10/302,747 patent/US7203538B2/en not_active Expired - Fee Related
-
2003
- 2003-11-20 JP JP2004555514A patent/JP4594735B2/ja not_active Expired - Fee Related
- 2003-11-20 AU AU2003291815A patent/AU2003291815A1/en not_active Abandoned
- 2003-11-20 EP EP03769000A patent/EP1562676B1/en not_active Expired - Lifetime
- 2003-11-20 AT AT03769000T patent/ATE357271T1/de not_active IP Right Cessation
- 2003-11-20 DE DE60312723T patent/DE60312723T2/de not_active Expired - Lifetime
- 2003-11-20 WO PCT/US2003/037155 patent/WO2004047918A1/en not_active Ceased
-
2007
- 2007-03-19 US US11/687,776 patent/US7991469B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070167987A1 (en) | 2007-07-19 |
| US7203538B2 (en) | 2007-04-10 |
| WO2004047918A1 (en) | 2004-06-10 |
| ATE357271T1 (de) | 2007-04-15 |
| EP1562676A1 (en) | 2005-08-17 |
| US7991469B2 (en) | 2011-08-02 |
| JP4594735B2 (ja) | 2010-12-08 |
| EP1562676B1 (en) | 2007-03-21 |
| AU2003291815A1 (en) | 2004-06-18 |
| US20040102811A1 (en) | 2004-05-27 |
| JP2006507093A (ja) | 2006-03-02 |
| DE60312723D1 (de) | 2007-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |