DE60305506D1 - Cephalosporine - Google Patents

Cephalosporine

Info

Publication number
DE60305506D1
DE60305506D1 DE60305506T DE60305506T DE60305506D1 DE 60305506 D1 DE60305506 D1 DE 60305506D1 DE 60305506 T DE60305506 T DE 60305506T DE 60305506 T DE60305506 T DE 60305506T DE 60305506 D1 DE60305506 D1 DE 60305506D1
Authority
DE
Germany
Prior art keywords
cephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60305506T
Other languages
English (en)
Other versions
DE60305506T2 (de
Inventor
Gerd Ascher
Werner Heilmayer
Michael Schranz
Josef Wieser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nabriva Therapeutics AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0216418A external-priority patent/GB0216418D0/en
Priority claimed from GB0222177A external-priority patent/GB0222177D0/en
Priority claimed from GB0223977A external-priority patent/GB0223977D0/en
Priority claimed from GB0223974A external-priority patent/GB0223974D0/en
Priority claimed from GB0223976A external-priority patent/GB0223976D0/en
Priority claimed from GB0223975A external-priority patent/GB0223975D0/en
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of DE60305506D1 publication Critical patent/DE60305506D1/de
Publication of DE60305506T2 publication Critical patent/DE60305506T2/de
Anticipated expiration legal-status Critical
Withdrawn - After Issue legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE60305506T 2002-07-15 2003-07-14 Cephalosporine Withdrawn - After Issue DE60305506T2 (de)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB0216418 2002-07-15
GB0216418A GB0216418D0 (en) 2002-07-15 2002-07-15 Organic compound
GB0222177A GB0222177D0 (en) 2002-09-24 2002-09-24 Organic compounds
GB0222177 2002-09-24
GB0223977A GB0223977D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223975 2002-10-15
GB0223976 2002-10-15
GB0223974A GB0223974D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223976A GB0223976D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223977 2002-10-15
GB0223975A GB0223975D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223974 2002-10-15
PCT/EP2003/007603 WO2004007505A1 (en) 2002-07-15 2003-07-14 Cephalosporins

Publications (2)

Publication Number Publication Date
DE60305506D1 true DE60305506D1 (de) 2006-06-29
DE60305506T2 DE60305506T2 (de) 2007-04-19

Family

ID=30119477

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60305506T Withdrawn - After Issue DE60305506T2 (de) 2002-07-15 2003-07-14 Cephalosporine

Country Status (23)

Country Link
US (1) US7485632B2 (de)
EP (1) EP1529050B1 (de)
JP (1) JP2005536499A (de)
KR (1) KR20050037553A (de)
CN (1) CN1678616A (de)
AR (1) AR040545A1 (de)
AT (1) ATE327239T1 (de)
AU (1) AU2003250056A1 (de)
BR (1) BR0312698A (de)
CA (1) CA2492373A1 (de)
CO (1) CO5680481A2 (de)
DE (1) DE60305506T2 (de)
EC (1) ECSP055538A (de)
ES (1) ES2268429T3 (de)
HK (1) HK1077299A1 (de)
IL (1) IL166120A0 (de)
MX (1) MXPA05000664A (de)
NO (1) NO20050781L (de)
PE (1) PE20040657A1 (de)
PL (1) PL373104A1 (de)
SI (1) SI1529050T1 (de)
TW (1) TW200422044A (de)
WO (1) WO2004007505A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000189171A (ja) * 1998-12-25 2000-07-11 Banyu Pharmaceut Co Ltd 新規なグアノシン三リン酸（ｇｔｐ）結合タンパク質共役型のレセプタ―タンパク質
CN106232576B (zh) * 2014-04-16 2019-03-01 Sika技术股份公司 含脒基或含胍基的硅烷

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5093989A (de) * 1973-10-25 1975-07-26
BR9608517A (pt) 1995-05-11 1999-06-08 Biochemie Gmbh Cefalosporinas antibacterianas
GB0301938D0 (en) * 2003-01-28 2003-02-26 Biochemie Gmbh Organic compounds

Also Published As

Publication number Publication date
ATE327239T1 (de) 2006-06-15
CN1678616A (zh) 2005-10-05
US7485632B2 (en) 2009-02-03
DE60305506T2 (de) 2007-04-19
AU2003250056A1 (en) 2004-02-02
SI1529050T1 (sl) 2006-10-31
TW200422044A (en) 2004-11-01
US20050234233A1 (en) 2005-10-20
ECSP055538A (es) 2005-03-10
IL166120A0 (en) 2006-01-15
AR040545A1 (es) 2005-04-13
ES2268429T3 (es) 2007-03-16
PE20040657A1 (es) 2004-11-08
BR0312698A (pt) 2005-05-03
CA2492373A1 (en) 2004-01-22
EP1529050A1 (de) 2005-05-11
WO2004007505A1 (en) 2004-01-22
EP1529050B1 (de) 2006-05-24
CO5680481A2 (es) 2006-09-29
KR20050037553A (ko) 2005-04-22
PL373104A1 (en) 2005-08-08
MXPA05000664A (es) 2005-04-25
NO20050781L (no) 2005-02-14
HK1077299A1 (en) 2006-02-10
JP2005536499A (ja) 2005-12-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NABRIVA THERAPEUTICS FORSCHUNG GMBH, WIEN, AT

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NABRIVA THERAPEUTICS AG, WIEN, AT

8330 Complete renunciation