ATE463248T1 - Cephem-verbindungen - Google Patents
Cephem-verbindungenInfo
- Publication number
- ATE463248T1 ATE463248T1 AT04773402T AT04773402T ATE463248T1 AT E463248 T1 ATE463248 T1 AT E463248T1 AT 04773402 T AT04773402 T AT 04773402T AT 04773402 T AT04773402 T AT 04773402T AT E463248 T1 ATE463248 T1 AT E463248T1
- Authority
- AT
- Austria
- Prior art keywords
- cephem compounds
- cephem
- compounds
- Prior art date
Links
- -1 CEPHEM COMPOUNDS Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003905084A AU2003905084A0 (en) | 2003-09-18 | Cephem Compounds | |
PCT/JP2004/014018 WO2005027909A1 (en) | 2003-09-18 | 2004-09-17 | Cephem compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE463248T1 true ATE463248T1 (de) | 2010-04-15 |
Family
ID=34318291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04773402T ATE463248T1 (de) | 2003-09-18 | 2004-09-17 | Cephem-verbindungen |
Country Status (13)
Country | Link |
---|---|
US (1) | US7192943B2 (de) |
EP (1) | EP1663245B1 (de) |
JP (1) | JP4643577B2 (de) |
KR (1) | KR20060069475A (de) |
CN (1) | CN1852715A (de) |
AR (1) | AR045768A1 (de) |
AT (1) | ATE463248T1 (de) |
CA (1) | CA2536636A1 (de) |
DE (1) | DE602004026451D1 (de) |
ES (1) | ES2340928T3 (de) |
MX (1) | MXPA06003068A (de) |
TW (1) | TW200524943A (de) |
WO (1) | WO2005027909A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60209341T2 (de) * | 2001-05-01 | 2006-08-03 | Astellas Pharma Inc. | Cephem-verbindungen |
ATE368042T1 (de) * | 2002-10-30 | 2007-08-15 | Astellas Pharma Inc | Cephemverbindungen |
AU2003902380A0 (en) * | 2003-05-16 | 2003-06-05 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
EP1994035A1 (de) * | 2006-03-16 | 2008-11-26 | Astellas Pharma Inc. | Cephemverbindungen und ihre verwendung als antimikrobiotika |
CN101448778A (zh) * | 2006-05-26 | 2009-06-03 | 艾博特公司 | Polo样激酶的抑制剂 |
EA028342B1 (ru) | 2011-09-09 | 2017-11-30 | Мерк Шарп И Доум Корп. | Способы лечения пневмонии |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
US9006421B2 (en) | 2013-03-14 | 2015-04-14 | Cubist Pharmaceuticals, Inc. | Cephalosporin compositions and methods of manufacture |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
AU2014227660B2 (en) | 2013-03-15 | 2014-11-06 | Merck Sharp & Dohme Llc | Ceftolozane antibiotic compositions |
US20140274991A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane pharmaceutical compositions |
WO2015035376A2 (en) | 2013-09-09 | 2015-03-12 | Calixa Therapeutics, Inc. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
US9695196B2 (en) | 2014-06-20 | 2017-07-04 | Merck Sharp & Dohme Corp. | Reactions of thiadiazolyl-oximinoacetic acid derivative compounds |
US10221196B2 (en) | 2014-08-15 | 2019-03-05 | Merck Sharp & Dohme Corp. | Intermediates in the synthesis of cephalosporin compounds |
CN106795175A (zh) | 2014-08-15 | 2017-05-31 | 默沙东公司 | 头孢菌素化合物的合成 |
US10000510B2 (en) | 2014-08-18 | 2018-06-19 | Merck Sharp & Dohme Corp. | Salt forms of ceftolozane |
US10035774B2 (en) | 2014-12-18 | 2018-07-31 | Merck Sharp & Dohme Corp. | Pyrazolyl carboxylic acid and pyrazolyl urea derivative compounds |
US10059680B2 (en) | 2014-12-18 | 2018-08-28 | Merck Sharp & Dohme Corp. | Thiadiazolyl-oximinoacetic acid derivative compounds |
US20160176897A1 (en) | 2014-12-23 | 2016-06-23 | Merck Sharp & Dohme Corp. | 7-aminocephem derivative compounds |
WO2016109259A2 (en) | 2014-12-30 | 2016-07-07 | Merck Sharp & Dohme Corp. | Synthesis of cephalosporin compounds |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR78245B (de) | 1980-09-12 | 1984-09-26 | Ciba Geigy Ag | |
JPS584789A (ja) * | 1981-04-03 | 1983-01-11 | Fujisawa Pharmaceut Co Ltd | 新規セフエム化合物およびその製造法 |
DE3279470D1 (en) | 1981-04-03 | 1989-04-06 | Fujisawa Pharmaceutical Co | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
US5194432A (en) | 1985-11-22 | 1993-03-16 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
CA1293719C (en) * | 1986-09-22 | 1991-12-31 | Takao Takaya | Cephem compounds and processes for preparation thereof |
US5210080A (en) * | 1987-09-07 | 1993-05-11 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US5663163A (en) * | 1987-09-07 | 1997-09-02 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and processes for preparation thereof |
IE63094B1 (en) * | 1987-09-14 | 1995-03-22 | Fujisawa Pharmaceutical Co | Cephem compound and a process for preparation thereof |
US5173485A (en) * | 1988-03-09 | 1992-12-22 | Fujisawa Pharmaceutical Company, Ltd. | Cephem compounds |
GB8805642D0 (en) * | 1988-03-09 | 1988-04-07 | Fujisawa Pharmaceutical Co | New cephem compounds & processes for preparation thereof |
GB8905301D0 (en) * | 1989-03-08 | 1989-04-19 | Fujisawa Pharmaceutical Co | New cephem compound and a process for preparation thereof |
US5215982A (en) * | 1989-11-10 | 1993-06-01 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
KR910015587A (ko) * | 1990-02-27 | 1991-09-30 | 후지사와 토모키치로 | 세펨 화합물 |
JPH03255087A (ja) * | 1990-03-05 | 1991-11-13 | Fujisawa Pharmaceut Co Ltd | 新規セフェム化合物およびその塩類 |
AU2577495A (en) * | 1994-05-23 | 1995-12-18 | Korea Institute Of Science And Technology | Cephalosporin compounds and processes for the preparation thereof |
JPH09110877A (ja) | 1995-10-17 | 1997-04-28 | Katayama Seiyakushiyo:Kk | セフェム化合物、その製造法及びそれを含有する抗菌剤 |
AUPN955596A0 (en) | 1996-04-30 | 1996-05-23 | Fujisawa Pharmaceutical Co., Ltd. | New compound |
TW526202B (en) * | 1998-11-27 | 2003-04-01 | Shionogi & Amp Co | Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity |
DE60209341T2 (de) | 2001-05-01 | 2006-08-03 | Astellas Pharma Inc. | Cephem-verbindungen |
ATE368042T1 (de) * | 2002-10-30 | 2007-08-15 | Astellas Pharma Inc | Cephemverbindungen |
AU2003902380A0 (en) * | 2003-05-16 | 2003-06-05 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
-
2004
- 2004-09-17 AR ARP040103366A patent/AR045768A1/es unknown
- 2004-09-17 TW TW093128132A patent/TW200524943A/zh unknown
- 2004-09-17 WO PCT/JP2004/014018 patent/WO2005027909A1/en active Application Filing
- 2004-09-17 JP JP2006526812A patent/JP4643577B2/ja not_active Expired - Fee Related
- 2004-09-17 CN CNA2004800269008A patent/CN1852715A/zh active Pending
- 2004-09-17 KR KR1020067003919A patent/KR20060069475A/ko not_active Application Discontinuation
- 2004-09-17 CA CA002536636A patent/CA2536636A1/en not_active Abandoned
- 2004-09-17 MX MXPA06003068A patent/MXPA06003068A/es not_active Application Discontinuation
- 2004-09-17 AT AT04773402T patent/ATE463248T1/de not_active IP Right Cessation
- 2004-09-17 EP EP04773402A patent/EP1663245B1/de not_active Not-in-force
- 2004-09-17 US US10/942,916 patent/US7192943B2/en not_active Expired - Fee Related
- 2004-09-17 DE DE602004026451T patent/DE602004026451D1/de active Active
- 2004-09-17 ES ES04773402T patent/ES2340928T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
US7192943B2 (en) | 2007-03-20 |
TW200524943A (en) | 2005-08-01 |
JP4643577B2 (ja) | 2011-03-02 |
MXPA06003068A (es) | 2006-08-25 |
DE602004026451D1 (de) | 2010-05-20 |
ES2340928T3 (es) | 2010-06-11 |
WO2005027909A1 (en) | 2005-03-31 |
JP2007505895A (ja) | 2007-03-15 |
KR20060069475A (ko) | 2006-06-21 |
EP1663245B1 (de) | 2010-04-07 |
US20050096306A1 (en) | 2005-05-05 |
AR045768A1 (es) | 2005-11-09 |
EP1663245A1 (de) | 2006-06-07 |
CN1852715A (zh) | 2006-10-25 |
CA2536636A1 (en) | 2005-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |