BR0312698A - Cefalosporinas - Google Patents

Cefalosporinas

Info

Publication number
BR0312698A
BR0312698A BR0312698-6A BR0312698A BR0312698A BR 0312698 A BR0312698 A BR 0312698A BR 0312698 A BR0312698 A BR 0312698A BR 0312698 A BR0312698 A BR 0312698A
Authority
BR
Brazil
Prior art keywords
cephalosporins
formula
substituents
useful
compound
Prior art date
Application number
BR0312698-6A
Other languages
English (en)
Inventor
Gerd Ascher
Werner Heilmayer
Michael Schranz
Josef Wieser
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0216418A external-priority patent/GB0216418D0/en
Priority claimed from GB0222177A external-priority patent/GB0222177D0/en
Priority claimed from GB0223975A external-priority patent/GB0223975D0/en
Priority claimed from GB0223974A external-priority patent/GB0223974D0/en
Priority claimed from GB0223976A external-priority patent/GB0223976D0/en
Priority claimed from GB0223977A external-priority patent/GB0223977D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of BR0312698A publication Critical patent/BR0312698A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

"CEFALOSPORINAS". A presente invenção refere-se a um composto da fórmula: ou da formula: em que os substituintes têm vários significados, úteis como um produto farmacêutico.
BR0312698-6A 2002-07-15 2003-07-14 Cefalosporinas BR0312698A (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0216418A GB0216418D0 (en) 2002-07-15 2002-07-15 Organic compound
GB0222177A GB0222177D0 (en) 2002-09-24 2002-09-24 Organic compounds
GB0223975A GB0223975D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223974A GB0223974D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223976A GB0223976D0 (en) 2002-10-15 2002-10-15 Organic compounds
GB0223977A GB0223977D0 (en) 2002-10-15 2002-10-15 Organic compounds
PCT/EP2003/007603 WO2004007505A1 (en) 2002-07-15 2003-07-14 Cephalosporins

Publications (1)

Publication Number Publication Date
BR0312698A true BR0312698A (pt) 2005-05-03

Family

ID=30119477

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0312698-6A BR0312698A (pt) 2002-07-15 2003-07-14 Cefalosporinas

Country Status (23)

Country Link
US (1) US7485632B2 (pt)
EP (1) EP1529050B1 (pt)
JP (1) JP2005536499A (pt)
KR (1) KR20050037553A (pt)
CN (1) CN1678616A (pt)
AR (1) AR040545A1 (pt)
AT (1) ATE327239T1 (pt)
AU (1) AU2003250056A1 (pt)
BR (1) BR0312698A (pt)
CA (1) CA2492373A1 (pt)
CO (1) CO5680481A2 (pt)
DE (1) DE60305506T2 (pt)
EC (1) ECSP055538A (pt)
ES (1) ES2268429T3 (pt)
HK (1) HK1077299A1 (pt)
IL (1) IL166120A0 (pt)
MX (1) MXPA05000664A (pt)
NO (1) NO20050781L (pt)
PE (1) PE20040657A1 (pt)
PL (1) PL373104A1 (pt)
SI (1) SI1529050T1 (pt)
TW (1) TW200422044A (pt)
WO (1) WO2004007505A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000189171A (ja) * 1998-12-25 2000-07-11 Banyu Pharmaceut Co Ltd 新規なグアノシン三リン酸（ｇｔｐ）結合タンパク質共役型のレセプタ―タンパク質
CN106459668A (zh) * 2014-04-16 2017-02-22 Sika技术股份公司 基于含硅烷基团的有机聚合物的迅速固化的无迁移组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5093989A (pt) * 1973-10-25 1975-07-26
CO4750666A1 (es) * 1995-05-11 1999-03-31 Biochemie Gmbh Compuestos de 7-acilamino-3-(imino)metil cefalosporina utiles como antibioticos
GB0301938D0 (en) * 2003-01-28 2003-02-26 Biochemie Gmbh Organic compounds

Also Published As

Publication number Publication date
TW200422044A (en) 2004-11-01
ATE327239T1 (de) 2006-06-15
EP1529050A1 (en) 2005-05-11
HK1077299A1 (en) 2006-02-10
US20050234233A1 (en) 2005-10-20
MXPA05000664A (es) 2005-04-25
KR20050037553A (ko) 2005-04-22
EP1529050B1 (en) 2006-05-24
CA2492373A1 (en) 2004-01-22
SI1529050T1 (sl) 2006-10-31
CN1678616A (zh) 2005-10-05
AR040545A1 (es) 2005-04-13
DE60305506T2 (de) 2007-04-19
ES2268429T3 (es) 2007-03-16
WO2004007505A1 (en) 2004-01-22
IL166120A0 (en) 2006-01-15
PL373104A1 (en) 2005-08-08
DE60305506D1 (de) 2006-06-29
CO5680481A2 (es) 2006-09-29
AU2003250056A1 (en) 2004-02-02
NO20050781L (no) 2005-02-14
PE20040657A1 (es) 2004-11-08
JP2005536499A (ja) 2005-12-02
ECSP055538A (es) 2005-03-10
US7485632B2 (en) 2009-02-03

Similar Documents

Publication Publication Date Title
BRPI0408347A (pt) derivados de pirimidina
BR0308979A (pt) Derivados de indolilmaleimida
BRPI0518758A2 (pt) compostos de acetamida como fungicidas
BR0312729A (pt) Novos derivados de indol-3-enxofre
TW200628161A (en) Novel betulin derivatives, preparation thereof and use thereof
TNSN05007A1 (en) Novel thiophenylglycoside derivatives, methods for production thereof, medicaments comprising said compounds and use thereof.
NO20063275L (no) Anvendelse av substituerte 2-aminotetraliner for forebyggende behandling av Parkinsons sykdom
BR0208338A (pt) Derivados de piridina
BRPI0512677A2 (pt) derivados de quinazolina
DE502005008057D1 (de) Substituierte cyclopenten-verbindungen
CY1109569T1 (el) Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινης
BRPI0417157A (pt) composto, composição farmacêutica, e, uso de um composto ou de uma composição farmacêutica
BR0314352A (pt) Indóis 2,7-substituìdos e seu uso como moduladores de 5-ht6
BR0309753A (pt) Processo para a preparação de derivados de 6-alquilideno penem
BR0208812A (pt) Derivados fenil heterociclil éter como inibidores de recaptação de serotonina
MXPA05012679A (es) Nuevos derivados de imidazoles, su preparacion y su uso como medicamento.
BRPI0411087A (pt) aperfeiçoamentos em ou relacionados a compostos orgánicos
BR0309668A (pt) Imidazolinilmetil aralquilsulfonamidas
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments
BR0312698A (pt) Cefalosporinas
BR0308223A (pt) Derivados de piridiniloxi como ligantes de receptor 5-ht
MXPA04001855A (es) Derivados de sistemas de indan-1-ol c2-sustituidos, metodos para la produccion de los mismos y su uso como medicamentos.
CA2443012A1 (en) Use of pyridoindolone derivatives for preparing medicines
EA200600054A1 (ru) 4-(аминометил) пиперидинбензамиды, обладающие 5нт- антагонистической активностью
BR0312760A (pt) Derivados de ácido 2,4-dihidroxibenzóico

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2157 DE 08/05/2012.