DE60300403D1 - Sequentiell quervernetztes Polyethylen für medizinische Implantate - Google Patents
Sequentiell quervernetztes Polyethylen für medizinische ImplantateInfo
- Publication number
- DE60300403D1 DE60300403D1 DE60300403T DE60300403T DE60300403D1 DE 60300403 D1 DE60300403 D1 DE 60300403D1 DE 60300403 T DE60300403 T DE 60300403T DE 60300403 T DE60300403 T DE 60300403T DE 60300403 D1 DE60300403 D1 DE 60300403D1
- Authority
- DE
- Germany
- Prior art keywords
- polyethylene
- irradiation
- annealing
- rod
- oxygen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/28—Treatment by wave energy or particle radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
- C08J3/247—Heating methods
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/04—Homopolymers or copolymers of ethene
- C08L23/06—Polyethene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2312/00—Crosslinking
- C08L2312/06—Crosslinking by radiation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38666002P | 2002-06-06 | 2002-06-06 | |
US386660P | 2002-06-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60300403D1 true DE60300403D1 (de) | 2005-04-28 |
DE60300403T2 DE60300403T2 (de) | 2006-03-09 |
Family
ID=29550211
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60300403T Expired - Lifetime DE60300403T2 (de) | 2002-06-06 | 2003-05-29 | Sequentiell quervernetztes Polyethylen für medizinische Implantate |
Country Status (7)
Country | Link |
---|---|
US (8) | US20030229155A1 (de) |
EP (1) | EP1369135B1 (de) |
JP (1) | JP4184872B2 (de) |
AT (1) | ATE291447T1 (de) |
AU (1) | AU2003204537B2 (de) |
CA (1) | CA2429930C (de) |
DE (1) | DE60300403T2 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8865788B2 (en) * | 1996-02-13 | 2014-10-21 | The General Hospital Corporation | Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices |
US8563623B2 (en) | 1996-02-13 | 2013-10-22 | The General Hospital Corporation | Radiation melt treated ultra high molecular weight polyethylene prosthetic devices |
CA2429930C (en) | 2002-06-06 | 2008-10-14 | Howmedica Osteonics Corp. | Sequentially cross-linked polyethylene |
US6932930B2 (en) * | 2003-03-10 | 2005-08-23 | Synecor, Llc | Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same |
JP2005237629A (ja) * | 2004-02-26 | 2005-09-08 | Kyocera Corp | 人工関節およびその製造方法 |
CN1738069A (zh) * | 2004-08-17 | 2006-02-22 | 国际商业机器公司 | 其电极具有增强注入特性的电子器件制造方法和电子器件 |
US8262976B2 (en) | 2004-10-07 | 2012-09-11 | Biomet Manufacturing Corp. | Solid state deformation processing of crosslinked high molecular weight polymeric materials |
US7462318B2 (en) | 2004-10-07 | 2008-12-09 | Biomet Manufacturing Corp. | Crosslinked polymeric material with enhanced strength and process for manufacturing |
US7344672B2 (en) | 2004-10-07 | 2008-03-18 | Biomet Manufacturing Corp. | Solid state deformation processing of crosslinked high molecular weight polymeric materials |
US7435372B2 (en) * | 2005-03-31 | 2008-10-14 | Zimmer, Inc. | Liquid bath annealing of polymers for orthopaedic implants |
AU2006259555B2 (en) * | 2005-06-14 | 2011-03-03 | Omni Life Science, Inc. | Crosslinked polyethylene article |
US7538379B1 (en) * | 2005-06-15 | 2009-05-26 | Actel Corporation | Non-volatile two-transistor programmable logic cell and array layout |
WO2007024689A2 (en) | 2005-08-22 | 2007-03-01 | The General Hospital Corporation Dba Massachusetts General Hospital | Oxidation resistant homogenized polymeric material |
EP2460636A1 (de) * | 2006-10-30 | 2012-06-06 | Smith & Nephew Orthopaedics AG | Verfahren mit Vernetzung von Polyethylen oder Verwendung von vernetztem Polyethylen |
US20100190920A1 (en) * | 2007-02-14 | 2010-07-29 | Anuj Bellare | Crosslinked polymers and methods of making the same |
US8641959B2 (en) | 2007-07-27 | 2014-02-04 | Biomet Manufacturing, Llc | Antioxidant doping of crosslinked polymers to form non-eluting bearing components |
US20100292374A1 (en) * | 2007-10-05 | 2010-11-18 | Anuj Bellare | Crosslinked polymers and methods of making the same |
US8133436B2 (en) * | 2008-08-05 | 2012-03-13 | Howmedica Osteonics Corp. | Polyethylene cross-linked with an anthocyanin |
FR2936702B1 (fr) * | 2008-10-02 | 2010-12-24 | Fournitures Hospitalieres Ind | Procede de fabrication d'implants pour prothese de hanche, et implant cotyloidien obtenu a partir de ce procede |
CA2706233C (en) * | 2009-06-04 | 2015-05-05 | Howmedica Osteonics Corp. | Orthopedic peek-on-polymer bearings |
GB0922339D0 (en) | 2009-12-21 | 2010-02-03 | Mcminn Derek J W | Acetabular cup prothesis and introducer thereof |
US9132209B2 (en) | 2010-05-07 | 2015-09-15 | Howmedia Osteonics Corp. | Surface crosslinked polyethylene |
WO2013169351A1 (en) * | 2012-05-09 | 2013-11-14 | Ticona Llc | Polymer composition and articles for use in low temperature environments that are wear resistant |
GB201219686D0 (en) | 2012-11-01 | 2012-12-12 | Invibio Ltd | Orthopaedic polymer-on-polymer bearings |
WO2014075727A1 (en) * | 2012-11-15 | 2014-05-22 | Abb Research Ltd | Cross-linked polyethylene used for electrical insulation applications |
US9586370B2 (en) | 2013-08-15 | 2017-03-07 | Biomet Manufacturing, Llc | Method for making ultra high molecular weight polyethylene |
WO2015073847A1 (en) * | 2013-11-15 | 2015-05-21 | Sabic Global Technologies B.V. | Methods of identifying crosslinking molecules for polymers |
AU2014366767A1 (en) * | 2013-12-16 | 2016-06-30 | 2266170 Ontario Inc. | Capsule with sensory attributes |
US20150266210A1 (en) * | 2014-03-21 | 2015-09-24 | Howmedica Osteonics Corp. | Annealing method for cross-linked polyethylene |
CN105172154B (zh) * | 2015-10-23 | 2017-10-24 | 安徽隆源成型科技有限公司 | 一种超高分子量聚乙烯的选区激光烧结成型方法 |
CN107303218A (zh) * | 2017-04-28 | 2017-10-31 | 上海旷视医疗科技有限公司 | 角/巩膜交联技术的安全控制及效能优化系统 |
US11952439B2 (en) | 2020-06-25 | 2024-04-09 | b-ONE Medical (Suzhou) Co., Ltd. | Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof |
CN113980324A (zh) * | 2021-11-02 | 2022-01-28 | 苏州微创关节医疗科技有限公司 | 超高分子量聚乙烯植入体及其制备方法和人工关节 |
Family Cites Families (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US543471A (en) * | 1895-07-30 | Wire winding and distributing machine | ||
BE544324A (de) * | 1955-01-11 | |||
US2904480A (en) * | 1955-06-06 | 1959-09-15 | Grace W R & Co | Polyethylene |
US3563869A (en) * | 1957-11-05 | 1971-02-16 | Grace W R & Co | Irradiated polyethylene |
US3022543A (en) * | 1958-02-07 | 1962-02-27 | Grace W R & Co | Method of producing film having improved shrink energy |
US3057791A (en) * | 1959-07-06 | 1962-10-09 | Phillips Petroleum Co | Radiation curing of polymers |
US3090770A (en) * | 1960-04-26 | 1963-05-21 | Grace W R & Co | Blended polyethylene compositions of improved clarity and method of making same |
US3162623A (en) * | 1961-12-26 | 1964-12-22 | Du Pont | Crosslinking of polymers with nitrogen fluorides |
US3362897A (en) | 1962-11-21 | 1968-01-09 | Gen Electric | Stable irradiated polyethylene |
US3297641A (en) * | 1964-01-17 | 1967-01-10 | Grace W R & Co | Process for cross-linking polyethylene |
DE1241994B (de) * | 1964-01-31 | 1967-06-08 | Glanzstoff Ag | Verfahren zur Absaettigung von Doppelbindungen in Polyolefinen |
DE1669649B2 (de) * | 1966-05-27 | 1971-05-19 | Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen | Verfahren zum herstellen feinteiliger schaumfoermiger olefin polymerisate mit hoher waermestandfestigkeit |
US3832827A (en) * | 1967-12-18 | 1974-09-03 | J Lemelson | Container forming and filling apparatus |
US3758273A (en) * | 1970-04-03 | 1973-09-11 | Gillette Co | Processes for sterilizing polypropylene objects |
JPS526314B2 (de) * | 1971-11-01 | 1977-02-21 | ||
AU523866B2 (en) * | 1978-04-18 | 1982-08-19 | Du Pont Canada Inc. | Manufacture of film |
US4241463A (en) | 1978-10-16 | 1980-12-30 | Precision Cast Specialties, Inc. | Prosthetic implant device |
WO1980002671A1 (en) | 1979-06-06 | 1980-12-11 | Nat Res Dev | Polymer processing |
US5017627A (en) | 1980-10-09 | 1991-05-21 | National Research Development Corporation | Composite material for use in orthopaedics |
US4586995A (en) | 1982-09-17 | 1986-05-06 | Phillips Petroleum Company | Polymer and irradiation treatment method |
JPS5971830A (ja) | 1982-10-18 | 1984-04-23 | Nippon Sheet Glass Co Ltd | 屈折率分布型レンズ体の製造方法 |
GB8332952D0 (en) * | 1983-12-09 | 1984-01-18 | Ward I M | Polymer irradiation |
US4587163A (en) * | 1984-03-06 | 1986-05-06 | Zachariades Anagnostis E | Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance |
CA1252265A (en) | 1984-03-30 | 1989-04-11 | Ian M. Ward | Tubular materials |
ATE54094T1 (de) | 1984-04-13 | 1990-07-15 | Nat Res Dev | Verfahren zum verformen im festen zustand. |
US4655769A (en) * | 1984-10-24 | 1987-04-07 | Zachariades Anagnostis E | Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states |
IN166935B (de) | 1985-01-31 | 1990-08-11 | Himont Inc | |
US4950151A (en) * | 1985-01-31 | 1990-08-21 | Zachariades Anagnostic E | Rolling die for producing high modulus products |
US4820466A (en) * | 1985-01-31 | 1989-04-11 | Zachariades Anagnostis E | Process for obtaining ultra-high modulus products |
DE3545116A1 (de) * | 1985-05-17 | 1986-11-20 | Transaktor KB International, Göteborg | Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung |
US4701288A (en) * | 1985-06-05 | 1987-10-20 | Bausch & Lomb Incorporated | Method of making articles of dissimilar polymer compositions |
JPS6274364A (ja) * | 1985-09-27 | 1987-04-06 | 株式会社 ニツシヨ− | 医療用具 |
GB2207436B (en) * | 1987-07-24 | 1991-07-24 | Nat Research And Dev Corp The | Solid phase deformation process |
US5047446A (en) | 1988-07-22 | 1991-09-10 | Himont Incorporated | Thermal treatment of irradiated propylene polymer material |
ZA896852B (en) | 1988-08-03 | 1991-04-24 | Iso Ster Proprietary Limited | Cross-linking of polymeric materials |
GB8827967D0 (en) | 1988-11-30 | 1989-01-05 | Ward I M | Die-free drawing |
BR8907794A (pt) | 1988-12-02 | 1991-08-27 | Du Pont | Polietileno linear de peso molecular ultra alto,artigos e processos de producao |
ATE122901T1 (de) | 1988-12-02 | 1995-06-15 | Du Pont | Verfahren zur herstellung von gegenständen aus polyethylen mit ultrahohem molekulargewicht. |
JPH02207436A (ja) | 1989-02-07 | 1990-08-17 | Fuji Electric Co Ltd | 回路しゃ断器のトリップクロスバー |
US5030402A (en) | 1989-03-17 | 1991-07-09 | Zachariades Anagnostis E | Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties |
US5037928A (en) * | 1989-10-24 | 1991-08-06 | E. I. Du Pont De Nemours And Company | Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles |
US5160677A (en) * | 1989-12-15 | 1992-11-03 | United States Surgical Corporation | Pressurized powder support for treating processes |
CA2031406C (en) | 1989-12-21 | 2002-05-28 | Paolo Galli | Graft copolymers of polyolefins and a method of producing same |
US5153039A (en) * | 1990-03-20 | 1992-10-06 | Paxon Polymer Company, L.P. | High density polyethylene article with oxygen barrier properties |
US5200439A (en) | 1990-04-13 | 1993-04-06 | Mitsui Toatsu Chemicals, Inc. | Method for increasing intrinsic viscosity of syndiotactic polypropylene |
NL9001745A (nl) * | 1990-08-01 | 1992-03-02 | Stamicarbon | Oplossing van ultra-hoog moleculair polyetheen. |
US5352732A (en) | 1990-08-07 | 1994-10-04 | E. I. Du Pont De Nemours And Company | Homogeneous, high modulus ultrahigh molecular weight polyethylene composites and processes for the preparation thereof |
US5348788A (en) * | 1991-01-30 | 1994-09-20 | Interpore Orthopaedics, Inc. | Mesh sheet with microscopic projections and holes |
US5292584A (en) | 1991-04-11 | 1994-03-08 | E. I. Du Pont De Nemours And Company | Ultrahigh molecular weight polyethylene and lightly-filled composites thereof |
US5508319A (en) * | 1991-06-21 | 1996-04-16 | Montell North America Inc. | High melt strength, ethylene polymer, process for making it, and use thereof |
US5466530A (en) | 1993-01-21 | 1995-11-14 | England; Garry L. | Biocompatible components fabricated from a substantially consolidated stock of material |
US5414049A (en) | 1993-06-01 | 1995-05-09 | Howmedica Inc. | Non-oxidizing polymeric medical implant |
WO1995006148A1 (en) * | 1993-08-20 | 1995-03-02 | Smith & Nephew Richards, Inc. | Self-reinforced ultra-high molecular weight polyethylene composites |
CA2177042C (en) * | 1994-09-21 | 2009-05-12 | Suong-Hyu Hyon | Ultra high molecular weight polyethylene molded article for artificial joints and method of preparing the same |
CA2166450C (en) * | 1995-01-20 | 2008-03-25 | Ronald Salovey | Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints |
US5609643A (en) | 1995-03-13 | 1997-03-11 | Johnson & Johnson Professional, Inc. | Knee joint prosthesis |
US5577368A (en) * | 1995-04-03 | 1996-11-26 | Johnson & Johnson Professional, Inc. | Method for improving wear resistance of polymeric bioimplantable components |
JP2984203B2 (ja) | 1995-10-31 | 1999-11-29 | 京セラ株式会社 | 人工関節用摺動部材の製造方法 |
US8563623B2 (en) * | 1996-02-13 | 2013-10-22 | The General Hospital Corporation | Radiation melt treated ultra high molecular weight polyethylene prosthetic devices |
US5879400A (en) * | 1996-02-13 | 1999-03-09 | Massachusetts Institute Of Technology | Melt-irradiated ultra high molecular weight polyethylene prosthetic devices |
RU2211008C2 (ru) * | 1996-02-13 | 2003-08-27 | Массачусетс Институт Оф Текнолоджи | Протезные устройства из полиэтилена сверхвысокой молекулярной массы, обработанного облучением и плавлением |
US5753182A (en) | 1996-02-14 | 1998-05-19 | Biomet, Inc. | Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components |
JP3565652B2 (ja) * | 1996-04-25 | 2004-09-15 | 富士通株式会社 | 荷電粒子ビーム露光装置用透過マスク及びそれを利用した露光装置 |
EP1795212A3 (de) * | 1996-07-09 | 2007-09-05 | Orthopaedic Hospital | Vernetzung von Polyethylen für geringen Verschleiss mit Hilfe von Strahlen- und Wärmebehandlung |
US6228900B1 (en) * | 1996-07-09 | 2001-05-08 | The Orthopaedic Hospital And University Of Southern California | Crosslinking of polyethylene for low wear using radiation and thermal treatments |
US6017975A (en) * | 1996-10-02 | 2000-01-25 | Saum; Kenneth Ashley | Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance |
AU4986497A (en) | 1996-10-15 | 1998-05-11 | Orthopaedic Hospital, The | Wear resistant surface-gradient cross-linked polyethylene |
US5874123A (en) | 1997-01-24 | 1999-02-23 | Park; Joon B. | Precoated polymeric prosthesis and process for making same |
CA2370208C (en) | 1999-04-21 | 2008-09-09 | Howmedica Osteonics Corp. | Selectively cross-linked polyethylene orthopedic devices |
US6432349B1 (en) * | 1999-06-29 | 2002-08-13 | Zimmer, Inc. | Process of making an articulating bearing surface |
US6143232A (en) | 1999-07-29 | 2000-11-07 | Bristol-Meyers Squibb Company | Method of manufacturing an articulating bearing surface for an orthopaedic implant |
US6184265B1 (en) * | 1999-07-29 | 2001-02-06 | Depuy Orthopaedics, Inc. | Low temperature pressure stabilization of implant component |
JP3598920B2 (ja) | 1999-12-10 | 2004-12-08 | 株式会社Nhvコーポレーション | 電子線照射方法 |
WO2001052110A2 (en) | 2000-01-13 | 2001-07-19 | Orbidex, Inc. | System and method of searching and gathering information on-line and off-line |
US6503439B1 (en) * | 2000-06-15 | 2003-01-07 | Albert H. Burstein | Process for forming shaped articles of ultra high molecular weight polyethylene suitable for use as a prosthetic device or a component thereof |
US6547828B2 (en) | 2001-02-23 | 2003-04-15 | Smith & Nephew, Inc. | Cross-linked ultra-high molecular weight polyethylene for medical implant use |
JP2005514496A (ja) | 2002-01-04 | 2005-05-19 | マサチューセッツ、ゼネラル、ホスピタル | 溶融体を下回る温度で調製した残留フリーラジカルが減少した高弾性率架橋ポリエチレン |
CA2429930C (en) * | 2002-06-06 | 2008-10-14 | Howmedica Osteonics Corp. | Sequentially cross-linked polyethylene |
US7384430B2 (en) * | 2004-06-30 | 2008-06-10 | Depuy Products, Inc. | Low crystalline polymeric material for orthopaedic implants and an associated method |
US7462318B2 (en) * | 2004-10-07 | 2008-12-09 | Biomet Manufacturing Corp. | Crosslinked polymeric material with enhanced strength and process for manufacturing |
US7836897B2 (en) | 2007-10-05 | 2010-11-23 | R.J. Reynolds Tobacco Company | Cigarette having configured lighting end |
-
2003
- 2003-05-27 CA CA002429930A patent/CA2429930C/en not_active Expired - Lifetime
- 2003-05-29 DE DE60300403T patent/DE60300403T2/de not_active Expired - Lifetime
- 2003-05-29 EP EP03253363A patent/EP1369135B1/de not_active Expired - Lifetime
- 2003-05-29 AT AT03253363T patent/ATE291447T1/de not_active IP Right Cessation
- 2003-06-04 US US10/454,815 patent/US20030229155A1/en not_active Abandoned
- 2003-06-05 AU AU2003204537A patent/AU2003204537B2/en not_active Expired
- 2003-06-06 JP JP2003161581A patent/JP4184872B2/ja not_active Expired - Fee Related
-
2004
- 2004-10-04 US US10/957,782 patent/US7517919B2/en not_active Expired - Lifetime
-
2008
- 2008-12-09 US US12/315,994 patent/US7714036B2/en not_active Expired - Lifetime
-
2010
- 2010-04-09 US US12/757,394 patent/US8030370B2/en not_active Expired - Lifetime
-
2011
- 2011-09-01 US US13/223,422 patent/US8324291B2/en not_active Expired - Lifetime
-
2012
- 2012-10-23 US US13/658,037 patent/US8680173B2/en not_active Expired - Lifetime
-
2014
- 2014-02-06 US US14/174,035 patent/US9181409B2/en not_active Expired - Lifetime
-
2015
- 2015-10-06 US US14/876,344 patent/US9650476B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1369135B1 (de) | 2005-03-23 |
US20120029160A1 (en) | 2012-02-02 |
US20030229155A1 (en) | 2003-12-11 |
EP1369135A1 (de) | 2003-12-10 |
CA2429930A1 (en) | 2003-12-06 |
ATE291447T1 (de) | 2005-04-15 |
US9181409B2 (en) | 2015-11-10 |
AU2003204537B2 (en) | 2008-02-28 |
US20100197881A1 (en) | 2010-08-05 |
US9650476B2 (en) | 2017-05-16 |
US20050043431A1 (en) | 2005-02-24 |
CA2429930C (en) | 2008-10-14 |
US8680173B2 (en) | 2014-03-25 |
US8324291B2 (en) | 2012-12-04 |
US7517919B2 (en) | 2009-04-14 |
JP4184872B2 (ja) | 2008-11-19 |
JP2004043798A (ja) | 2004-02-12 |
US20130046042A1 (en) | 2013-02-21 |
AU2003204537A1 (en) | 2004-01-08 |
DE60300403T2 (de) | 2006-03-09 |
US20090105439A1 (en) | 2009-04-23 |
US7714036B2 (en) | 2010-05-11 |
US20140194548A1 (en) | 2014-07-10 |
US20160024261A1 (en) | 2016-01-28 |
US8030370B2 (en) | 2011-10-04 |
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Inventor name: WANG, AIGUO, WAYNE, N.J., US Inventor name: DUMBLETON, JOHN H., RIDGEWOOD, N.J., US Inventor name: ESSNER, AARON, BLOOMINGDALE, N.J., US Inventor name: YAU, SHI-SHEN, BERKELEY HEIGHTS, N.J., US |