ATE291447T1 - Sequentiell quervernetztes polyethylen für medizinische implantate - Google Patents

Sequentiell quervernetztes polyethylen für medizinische implantate

Info

Publication number
ATE291447T1
ATE291447T1 AT03253363T AT03253363T ATE291447T1 AT E291447 T1 ATE291447 T1 AT E291447T1 AT 03253363 T AT03253363 T AT 03253363T AT 03253363 T AT03253363 T AT 03253363T AT E291447 T1 ATE291447 T1 AT E291447T1
Authority
AT
Austria
Prior art keywords
polyethylene
irradiation
annealing
rod
oxygen
Prior art date
Application number
AT03253363T
Other languages
English (en)
Inventor
Aiguo Wang
John H Dumbleton
Original Assignee
Howmedica Osteonics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howmedica Osteonics Corp filed Critical Howmedica Osteonics Corp
Application granted granted Critical
Publication of ATE291447T1 publication Critical patent/ATE291447T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/28—Treatment by wave energy or particle radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/247—Heating methods
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking
    • C08L2312/06—Crosslinking by radiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
AT03253363T 2002-06-06 2003-05-29 Sequentiell quervernetztes polyethylen für medizinische implantate ATE291447T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38666002P 2002-06-06 2002-06-06

Publications (1)

Publication Number Publication Date
ATE291447T1 true ATE291447T1 (de) 2005-04-15

Family

ID=29550211

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03253363T ATE291447T1 (de) 2002-06-06 2003-05-29 Sequentiell quervernetztes polyethylen für medizinische implantate

Country Status (7)

Country Link
US (8) US20030229155A1 (de)
EP (1) EP1369135B1 (de)
JP (1) JP4184872B2 (de)
AT (1) ATE291447T1 (de)
AU (1) AU2003204537B2 (de)
CA (1) CA2429930C (de)
DE (1) DE60300403T2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US8563623B2 (en) 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
CA2429930C (en) 2002-06-06 2008-10-14 Howmedica Osteonics Corp. Sequentially cross-linked polyethylene
US6932930B2 (en) * 2003-03-10 2005-08-23 Synecor, Llc Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
JP2005237629A (ja) * 2004-02-26 2005-09-08 Kyocera Corp 人工関節およびその製造方法
CN1738069A (zh) * 2004-08-17 2006-02-22 国际商业机器公司 其电极具有增强注入特性的电子器件制造方法和电子器件
US8262976B2 (en) 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7462318B2 (en) 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
US7344672B2 (en) 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7435372B2 (en) * 2005-03-31 2008-10-14 Zimmer, Inc. Liquid bath annealing of polymers for orthopaedic implants
AU2006259555B2 (en) * 2005-06-14 2011-03-03 Omni Life Science, Inc. Crosslinked polyethylene article
US7538379B1 (en) * 2005-06-15 2009-05-26 Actel Corporation Non-volatile two-transistor programmable logic cell and array layout
WO2007024689A2 (en) 2005-08-22 2007-03-01 The General Hospital Corporation Dba Massachusetts General Hospital Oxidation resistant homogenized polymeric material
EP2460636A1 (de) * 2006-10-30 2012-06-06 Smith & Nephew Orthopaedics AG Verfahren mit Vernetzung von Polyethylen oder Verwendung von vernetztem Polyethylen
US20100190920A1 (en) * 2007-02-14 2010-07-29 Anuj Bellare Crosslinked polymers and methods of making the same
US8641959B2 (en) 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
US20100292374A1 (en) * 2007-10-05 2010-11-18 Anuj Bellare Crosslinked polymers and methods of making the same
US8133436B2 (en) * 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
FR2936702B1 (fr) * 2008-10-02 2010-12-24 Fournitures Hospitalieres Ind Procede de fabrication d'implants pour prothese de hanche, et implant cotyloidien obtenu a partir de ce procede
CA2706233C (en) * 2009-06-04 2015-05-05 Howmedica Osteonics Corp. Orthopedic peek-on-polymer bearings
GB0922339D0 (en) 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
US9132209B2 (en) 2010-05-07 2015-09-15 Howmedia Osteonics Corp. Surface crosslinked polyethylene
WO2013169351A1 (en) * 2012-05-09 2013-11-14 Ticona Llc Polymer composition and articles for use in low temperature environments that are wear resistant
GB201219686D0 (en) 2012-11-01 2012-12-12 Invibio Ltd Orthopaedic polymer-on-polymer bearings
WO2014075727A1 (en) * 2012-11-15 2014-05-22 Abb Research Ltd Cross-linked polyethylene used for electrical insulation applications
US9586370B2 (en) 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
WO2015073847A1 (en) * 2013-11-15 2015-05-21 Sabic Global Technologies B.V. Methods of identifying crosslinking molecules for polymers
AU2014366767A1 (en) * 2013-12-16 2016-06-30 2266170 Ontario Inc. Capsule with sensory attributes
US20150266210A1 (en) * 2014-03-21 2015-09-24 Howmedica Osteonics Corp. Annealing method for cross-linked polyethylene
CN105172154B (zh) * 2015-10-23 2017-10-24 安徽隆源成型科技有限公司 一种超高分子量聚乙烯的选区激光烧结成型方法
CN107303218A (zh) * 2017-04-28 2017-10-31 上海旷视医疗科技有限公司 角/巩膜交联技术的安全控制及效能优化系统
US11952439B2 (en) 2020-06-25 2024-04-09 b-ONE Medical (Suzhou) Co., Ltd. Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof
CN113980324A (zh) * 2021-11-02 2022-01-28 苏州微创关节医疗科技有限公司 超高分子量聚乙烯植入体及其制备方法和人工关节

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US543471A (en) * 1895-07-30 Wire winding and distributing machine
BE544324A (de) * 1955-01-11
US2904480A (en) * 1955-06-06 1959-09-15 Grace W R & Co Polyethylene
US3563869A (en) * 1957-11-05 1971-02-16 Grace W R & Co Irradiated polyethylene
US3022543A (en) * 1958-02-07 1962-02-27 Grace W R & Co Method of producing film having improved shrink energy
US3057791A (en) * 1959-07-06 1962-10-09 Phillips Petroleum Co Radiation curing of polymers
US3090770A (en) * 1960-04-26 1963-05-21 Grace W R & Co Blended polyethylene compositions of improved clarity and method of making same
US3162623A (en) * 1961-12-26 1964-12-22 Du Pont Crosslinking of polymers with nitrogen fluorides
US3362897A (en) 1962-11-21 1968-01-09 Gen Electric Stable irradiated polyethylene
US3297641A (en) * 1964-01-17 1967-01-10 Grace W R & Co Process for cross-linking polyethylene
DE1241994B (de) * 1964-01-31 1967-06-08 Glanzstoff Ag Verfahren zur Absaettigung von Doppelbindungen in Polyolefinen
DE1669649B2 (de) * 1966-05-27 1971-05-19 Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen Verfahren zum herstellen feinteiliger schaumfoermiger olefin polymerisate mit hoher waermestandfestigkeit
US3832827A (en) * 1967-12-18 1974-09-03 J Lemelson Container forming and filling apparatus
US3758273A (en) * 1970-04-03 1973-09-11 Gillette Co Processes for sterilizing polypropylene objects
JPS526314B2 (de) * 1971-11-01 1977-02-21
AU523866B2 (en) * 1978-04-18 1982-08-19 Du Pont Canada Inc. Manufacture of film
US4241463A (en) 1978-10-16 1980-12-30 Precision Cast Specialties, Inc. Prosthetic implant device
WO1980002671A1 (en) 1979-06-06 1980-12-11 Nat Res Dev Polymer processing
US5017627A (en) 1980-10-09 1991-05-21 National Research Development Corporation Composite material for use in orthopaedics
US4586995A (en) 1982-09-17 1986-05-06 Phillips Petroleum Company Polymer and irradiation treatment method
JPS5971830A (ja) 1982-10-18 1984-04-23 Nippon Sheet Glass Co Ltd 屈折率分布型レンズ体の製造方法
GB8332952D0 (en) * 1983-12-09 1984-01-18 Ward I M Polymer irradiation
US4587163A (en) * 1984-03-06 1986-05-06 Zachariades Anagnostis E Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance
CA1252265A (en) 1984-03-30 1989-04-11 Ian M. Ward Tubular materials
ATE54094T1 (de) 1984-04-13 1990-07-15 Nat Res Dev Verfahren zum verformen im festen zustand.
US4655769A (en) * 1984-10-24 1987-04-07 Zachariades Anagnostis E Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states
IN166935B (de) 1985-01-31 1990-08-11 Himont Inc
US4950151A (en) * 1985-01-31 1990-08-21 Zachariades Anagnostic E Rolling die for producing high modulus products
US4820466A (en) * 1985-01-31 1989-04-11 Zachariades Anagnostis E Process for obtaining ultra-high modulus products
DE3545116A1 (de) * 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
US4701288A (en) * 1985-06-05 1987-10-20 Bausch & Lomb Incorporated Method of making articles of dissimilar polymer compositions
JPS6274364A (ja) * 1985-09-27 1987-04-06 株式会社　ニツシヨ− 医療用具
GB2207436B (en) * 1987-07-24 1991-07-24 Nat Research And Dev Corp The Solid phase deformation process
US5047446A (en) 1988-07-22 1991-09-10 Himont Incorporated Thermal treatment of irradiated propylene polymer material
ZA896852B (en) 1988-08-03 1991-04-24 Iso Ster Proprietary Limited Cross-linking of polymeric materials
GB8827967D0 (en) 1988-11-30 1989-01-05 Ward I M Die-free drawing
BR8907794A (pt) 1988-12-02 1991-08-27 Du Pont Polietileno linear de peso molecular ultra alto,artigos e processos de producao
ATE122901T1 (de) 1988-12-02 1995-06-15 Du Pont Verfahren zur herstellung von gegenständen aus polyethylen mit ultrahohem molekulargewicht.
JPH02207436A (ja) 1989-02-07 1990-08-17 Fuji Electric Co Ltd 回路しゃ断器のトリップクロスバー
US5030402A (en) 1989-03-17 1991-07-09 Zachariades Anagnostis E Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties
US5037928A (en) * 1989-10-24 1991-08-06 E. I. Du Pont De Nemours And Company Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
US5160677A (en) * 1989-12-15 1992-11-03 United States Surgical Corporation Pressurized powder support for treating processes
CA2031406C (en) 1989-12-21 2002-05-28 Paolo Galli Graft copolymers of polyolefins and a method of producing same
US5153039A (en) * 1990-03-20 1992-10-06 Paxon Polymer Company, L.P. High density polyethylene article with oxygen barrier properties
US5200439A (en) 1990-04-13 1993-04-06 Mitsui Toatsu Chemicals, Inc. Method for increasing intrinsic viscosity of syndiotactic polypropylene
NL9001745A (nl) * 1990-08-01 1992-03-02 Stamicarbon Oplossing van ultra-hoog moleculair polyetheen.
US5352732A (en) 1990-08-07 1994-10-04 E. I. Du Pont De Nemours And Company Homogeneous, high modulus ultrahigh molecular weight polyethylene composites and processes for the preparation thereof
US5348788A (en) * 1991-01-30 1994-09-20 Interpore Orthopaedics, Inc. Mesh sheet with microscopic projections and holes
US5292584A (en) 1991-04-11 1994-03-08 E. I. Du Pont De Nemours And Company Ultrahigh molecular weight polyethylene and lightly-filled composites thereof
US5508319A (en) * 1991-06-21 1996-04-16 Montell North America Inc. High melt strength, ethylene polymer, process for making it, and use thereof
US5466530A (en) 1993-01-21 1995-11-14 England; Garry L. Biocompatible components fabricated from a substantially consolidated stock of material
US5414049A (en) 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
WO1995006148A1 (en) * 1993-08-20 1995-03-02 Smith & Nephew Richards, Inc. Self-reinforced ultra-high molecular weight polyethylene composites
CA2177042C (en) * 1994-09-21 2009-05-12 Suong-Hyu Hyon Ultra high molecular weight polyethylene molded article for artificial joints and method of preparing the same
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5609643A (en) 1995-03-13 1997-03-11 Johnson & Johnson Professional, Inc. Knee joint prosthesis
US5577368A (en) * 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
JP2984203B2 (ja) 1995-10-31 1999-11-29 京セラ株式会社 人工関節用摺動部材の製造方法
US8563623B2 (en) * 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
RU2211008C2 (ru) * 1996-02-13 2003-08-27 Массачусетс Институт Оф Текнолоджи Протезные устройства из полиэтилена сверхвысокой молекулярной массы, обработанного облучением и плавлением
US5753182A (en) 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
JP3565652B2 (ja) * 1996-04-25 2004-09-15 富士通株式会社 荷電粒子ビーム露光装置用透過マスク及びそれを利用した露光装置
EP1795212A3 (de) * 1996-07-09 2007-09-05 Orthopaedic Hospital Vernetzung von Polyethylen für geringen Verschleiss mit Hilfe von Strahlen- und Wärmebehandlung
US6228900B1 (en) * 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
AU4986497A (en) 1996-10-15 1998-05-11 Orthopaedic Hospital, The Wear resistant surface-gradient cross-linked polyethylene
US5874123A (en) 1997-01-24 1999-02-23 Park; Joon B. Precoated polymeric prosthesis and process for making same
CA2370208C (en) 1999-04-21 2008-09-09 Howmedica Osteonics Corp. Selectively cross-linked polyethylene orthopedic devices
US6432349B1 (en) * 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
US6143232A (en) 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
US6184265B1 (en) * 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
JP3598920B2 (ja) 1999-12-10 2004-12-08 株式会社Ｎｈｖコーポレーション 電子線照射方法
WO2001052110A2 (en) 2000-01-13 2001-07-19 Orbidex, Inc. System and method of searching and gathering information on-line and off-line
US6503439B1 (en) * 2000-06-15 2003-01-07 Albert H. Burstein Process for forming shaped articles of ultra high molecular weight polyethylene suitable for use as a prosthetic device or a component thereof
US6547828B2 (en) 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use
JP2005514496A (ja) 2002-01-04 2005-05-19 マサチューセッツ、ゼネラル、ホスピタル 溶融体を下回る温度で調製した残留フリーラジカルが減少した高弾性率架橋ポリエチレン
CA2429930C (en) * 2002-06-06 2008-10-14 Howmedica Osteonics Corp. Sequentially cross-linked polyethylene
US7384430B2 (en) * 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
US7462318B2 (en) * 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
US7836897B2 (en) 2007-10-05 2010-11-23 R.J. Reynolds Tobacco Company Cigarette having configured lighting end

Also Published As

Publication number Publication date
EP1369135B1 (de) 2005-03-23
US20120029160A1 (en) 2012-02-02
US20030229155A1 (en) 2003-12-11
EP1369135A1 (de) 2003-12-10
CA2429930A1 (en) 2003-12-06
US9181409B2 (en) 2015-11-10
AU2003204537B2 (en) 2008-02-28
US20100197881A1 (en) 2010-08-05
US9650476B2 (en) 2017-05-16
US20050043431A1 (en) 2005-02-24
CA2429930C (en) 2008-10-14
US8680173B2 (en) 2014-03-25
US8324291B2 (en) 2012-12-04
US7517919B2 (en) 2009-04-14
JP4184872B2 (ja) 2008-11-19
JP2004043798A (ja) 2004-02-12
US20130046042A1 (en) 2013-02-21
AU2003204537A1 (en) 2004-01-08
DE60300403T2 (de) 2006-03-09
US20090105439A1 (en) 2009-04-23
US7714036B2 (en) 2010-05-11
US20140194548A1 (en) 2014-07-10
DE60300403D1 (de) 2005-04-28
US20160024261A1 (en) 2016-01-28
US8030370B2 (en) 2011-10-04

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