DE60238471D1 - Proteosom-liposaccharid-vakzine-adjuvans - Google Patents

Proteosom-liposaccharid-vakzine-adjuvans

Info

Publication number
DE60238471D1
DE60238471D1 DE60238471T DE60238471T DE60238471D1 DE 60238471 D1 DE60238471 D1 DE 60238471D1 DE 60238471 T DE60238471 T DE 60238471T DE 60238471 T DE60238471 T DE 60238471T DE 60238471 D1 DE60238471 D1 DE 60238471D1
Authority
DE
Germany
Prior art keywords
liposaccharide
proteosome
variety
vaccine adjuvant
bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60238471T
Other languages
German (de)
English (en)
Inventor
David S Burt
George H Lowell
Gregory L White
David Jones
Clement Rioux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ID Biomedical Corp of Quebec
Original Assignee
ID Biomedical Corp of Quebec
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ID Biomedical Corp of Quebec filed Critical ID Biomedical Corp of Quebec
Application granted granted Critical
Publication of DE60238471D1 publication Critical patent/DE60238471D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DE60238471T 2001-03-09 2002-03-11 Proteosom-liposaccharid-vakzine-adjuvans Expired - Lifetime DE60238471D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27423201P 2001-03-09 2001-03-09
US32729701P 2001-10-09 2001-10-09
PCT/US2002/007108 WO2002072012A2 (fr) 2001-03-09 2002-03-11 Nouvel adjuvant de vaccin proteosome-liposaccharide

Publications (1)

Publication Number Publication Date
DE60238471D1 true DE60238471D1 (de) 2011-01-13

Family

ID=26956684

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60238471T Expired - Lifetime DE60238471D1 (de) 2001-03-09 2002-03-11 Proteosom-liposaccharid-vakzine-adjuvans

Country Status (9)

Country Link
US (2) US7524509B2 (fr)
EP (1) EP1372706B1 (fr)
JP (2) JP4137640B2 (fr)
AT (1) ATE489968T1 (fr)
AU (1) AU2002245636B2 (fr)
CA (1) CA2438425C (fr)
DE (1) DE60238471D1 (fr)
MX (1) MXPA03008154A (fr)
WO (1) WO2002072012A2 (fr)

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US7255867B2 (en) * 2002-11-15 2007-08-14 Id Biomedical Corporation Of Quebec Vaccine
EP1622641A2 (fr) * 2003-05-05 2006-02-08 ID Biomedical Corporation of Quebec Vacciner contre des maladies infectieuses utilisant des proteosomes
US7368537B2 (en) * 2003-07-15 2008-05-06 Id Biomedical Corporation Of Quebec Subunit vaccine against respiratory syncytial virus infection
EP1667713A1 (fr) * 2003-09-15 2006-06-14 ID Biomedical Corporation of Quebec Vaccin antirougeoleux sous-unitaire
US8173140B2 (en) * 2003-10-22 2012-05-08 Id Biomedical Corporation Of Quebec Compositions and methods for activating innate and allergic immunity
CU23420A1 (es) * 2003-12-30 2009-09-08 Univ De Cambridge Proteoliposomas y sus derivados como adyuvantes inductores de respuesta citotóxica y las formulaciones resultantes
JP5274011B2 (ja) * 2004-06-25 2013-08-28 アイディー バイオメディカル コーポレイション オブ ケベック 神経障害を治療するための組成物および方法
US20060286124A1 (en) * 2004-06-30 2006-12-21 Id Biomedical Corporation Of Quebec Vaccine compositions and methods of treating coronavirus infection
NZ580974A (en) 2005-02-18 2011-05-27 Novartis Vaccines & Diagnostic Immunogens from uropathogenic escherichia coli
LT2351772T (lt) 2005-02-18 2016-10-10 Glaxosmithkline Biologicals Sa Baltymai ir nukleorūgštys iš su meningitu/sepsiu susijusių escherichia coli
DK2368572T3 (da) 2005-11-04 2020-05-25 Seqirus Uk Ltd Adjuvansvacciner med ikke-virionantigener fremstillet fra influenza-virusser dyrket i cellekultur
WO2007085969A2 (fr) 2006-01-27 2007-08-02 Novartis Vaccines And Diagnostics Gmbh & Co Kg Vaccins contre la grippe contenant des hémaglutinines et des protéines matricielles
JP2009534303A (ja) 2006-03-24 2009-09-24 ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー 冷蔵しないインフルエンザワクチンの保存
PL2054431T3 (pl) 2006-06-09 2012-07-31 Novartis Ag Konformery adhezyn bakteryjnych
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
WO2008020330A2 (fr) 2006-08-16 2008-02-21 Novartis Ag Immunogènes pour escherichia coli uropathogène
CA3016948A1 (fr) 2006-09-11 2008-03-20 Seqirus UK Limited Fabrication de vaccins contre le virus grippal sans utiliser d'oeufs
NZ577405A (en) 2006-12-06 2012-08-31 Novartis Ag Vaccines including antigen from four strains of influenza virus
CA2692200A1 (fr) 2007-06-27 2008-12-31 Novartis Ag Vaccins antigrippaux a faible teneur en additifs
GB0713880D0 (en) 2007-07-17 2007-08-29 Novartis Ag Conjugate purification
WO2009062132A2 (fr) 2007-11-09 2009-05-14 California Institute Of Technology Composés immunorégulateurs et compositions et procédés apparentés
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
SI2222710T1 (sl) 2007-12-24 2016-11-30 Id Biomedical Corporation Of Quebec Rekombinatni RSV antigeni
WO2010003219A1 (fr) * 2008-06-17 2010-01-14 Universite Laval Compositions contenant des porines de salmonelle et leurs utilisations comme adjuvants et vaccins
US20110171259A1 (en) 2008-09-05 2011-07-14 Martin Gagne Novel Compositions and Adjuvants
JP2012524910A (ja) * 2009-04-23 2012-10-18 カリフォルニア インスティチュート オブ テクノロジー 免疫調節物質の同定方法及びシステム
WO2010149743A2 (fr) 2009-06-24 2010-12-29 Id Biomedical Corporation Of Quebec Vaccin
CA2766211A1 (fr) 2009-06-24 2010-12-29 Glaxosmithkline Biologicals S.A. Antigenes recombinants du vrs
EP3988115A3 (fr) 2009-07-15 2022-08-17 GlaxoSmithKline Biologicals S.A. Compositions à base de protéine f du vrs et procédés de fabrication associés
WO2011106525A2 (fr) 2010-02-26 2011-09-01 The Brigham And Women's Hospital, Inc. Procédé de traitement d'angiopathie amyloïde cérébrale
ES2694100T3 (es) 2010-04-07 2018-12-18 California Institute Of Technology Vehículo para distribuir un compuesto en una membrana mucosa y composiciones, procedimientos y sistemas relacionados
JP2013532008A (ja) 2010-05-28 2013-08-15 テトリス オンライン インコーポレイテッド 対話式ハイブリッド非同期コンピュータ・ゲーム・インフラストラクチャ
US9192661B2 (en) 2010-07-06 2015-11-24 Novartis Ag Delivery of self-replicating RNA using biodegradable polymer particles
CA2815275C (fr) 2010-10-27 2023-09-19 Glaxosmithkline Biologicals S.A. Compositions immunogeniques derivees de shigella
WO2013009945A1 (fr) 2011-07-12 2013-01-17 The Brigham And Women's Hospital, Inc. Compositions de psa contenant des lipides, procédés d'isolement et procédés pour les utiliser
WO2013108272A2 (fr) 2012-01-20 2013-07-25 International Centre For Genetic Engineering And Biotechnology Vaccin antipaludique ciblant le stade sanguin
JP2015525794A (ja) 2012-08-06 2015-09-07 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 乳児においてｒｓｖ及び百日咳菌に対する免疫応答を惹起するための方法
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
EP3608332B1 (fr) 2013-03-15 2022-06-01 GlaxoSmithKline Biologicals SA Vaccin contre le rhinovirus humain
JP2016521284A (ja) 2013-05-10 2016-07-21 カリフォルニア インスティチュート オブ テクノロジー 大腸ガンのプロバイオティクスによる防止および処置
BE1022008B1 (fr) 2013-08-05 2016-02-03 Glaxosmithkline Biologicals S.A. Compositions immunogenes combinees
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CA2997211A1 (fr) 2015-08-19 2017-02-23 President And Fellows Of Harvard College Compositions de psa lipides et procedes associes
WO2018014012A1 (fr) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Compositions de glycolipide et procédés d'utilisation
WO2023114727A1 (fr) 2021-12-13 2023-06-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Système de vaccin du bactériophage lambda

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CN1211192A (zh) * 1995-09-18 1999-03-17 美国陆军医疗材料研究指挥部 生产非共价复合的多价蛋白体亚基疫苗的改进方法
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US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US6468546B1 (en) 1998-12-17 2002-10-22 Corixa Corporation Compositions and methods for therapy and diagnosis of ovarian cancer
ATE331530T1 (de) * 2000-02-15 2006-07-15 Id Biomedical Corp Quebec Proteasom-influenzavirus-impfstoffzusammensetzu g
US7368537B2 (en) * 2003-07-15 2008-05-06 Id Biomedical Corporation Of Quebec Subunit vaccine against respiratory syncytial virus infection
EP1667713A1 (fr) * 2003-09-15 2006-06-14 ID Biomedical Corporation of Quebec Vaccin antirougeoleux sous-unitaire
US8173140B2 (en) * 2003-10-22 2012-05-08 Id Biomedical Corporation Of Quebec Compositions and methods for activating innate and allergic immunity
US20060286124A1 (en) * 2004-06-30 2006-12-21 Id Biomedical Corporation Of Quebec Vaccine compositions and methods of treating coronavirus infection
US20060228233A1 (en) * 2005-03-31 2006-10-12 Arimitsu Of North America, Inc. Pump and motor assembly

Also Published As

Publication number Publication date
ATE489968T1 (de) 2010-12-15
CA2438425A1 (fr) 2002-09-19
JP2007031457A (ja) 2007-02-08
WO2002072012A3 (fr) 2003-02-27
WO2002072012A2 (fr) 2002-09-19
CA2438425C (fr) 2012-05-01
JP2004521925A (ja) 2004-07-22
US20090252762A1 (en) 2009-10-08
JP4137640B2 (ja) 2008-08-20
EP1372706B1 (fr) 2010-12-01
US20030044425A1 (en) 2003-03-06
EP1372706A4 (fr) 2004-08-25
AU2002245636B2 (en) 2004-10-14
US7524509B2 (en) 2009-04-28
EP1372706A2 (fr) 2004-01-02
MXPA03008154A (es) 2004-11-12

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