DE60235375D1 - Platinkomplexe und deren verwendung in der therapie - Google Patents

Platinkomplexe und deren verwendung in der therapie

Info

Publication number
DE60235375D1
DE60235375D1 DE60235375T DE60235375T DE60235375D1 DE 60235375 D1 DE60235375 D1 DE 60235375D1 DE 60235375 T DE60235375 T DE 60235375T DE 60235375 T DE60235375 T DE 60235375T DE 60235375 D1 DE60235375 D1 DE 60235375D1
Authority
DE
Germany
Prior art keywords
platinum complexes
therapy
present
concerns novel
novel platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235375T
Other languages
English (en)
Inventor
Yechezkel Barenholz
Dan Gibson
Yousef Najajreh
Elena Khazanov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Application granted granted Critical
Publication of DE60235375D1 publication Critical patent/DE60235375D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
DE60235375T 2001-08-23 2002-08-21 Platinkomplexe und deren verwendung in der therapie Expired - Lifetime DE60235375D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31411501P 2001-08-23 2001-08-23
PCT/IL2002/000687 WO2003017998A1 (en) 2001-08-23 2002-08-21 Platinum complexes and their use in cancer treatment

Publications (1)

Publication Number Publication Date
DE60235375D1 true DE60235375D1 (de) 2010-04-01

Family

ID=23218625

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235375T Expired - Lifetime DE60235375D1 (de) 2001-08-23 2002-08-21 Platinkomplexe und deren verwendung in der therapie

Country Status (9)

Country Link
US (1) US7122668B2 (de)
EP (1) EP1420775B1 (de)
JP (1) JP2005501859A (de)
AT (1) ATE457992T1 (de)
CA (1) CA2456348A1 (de)
DE (1) DE60235375D1 (de)
ES (1) ES2339228T3 (de)
IL (1) IL159993A0 (de)
WO (1) WO2003017998A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9502799D0 (en) * 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
JP5107573B2 (ja) 2003-04-25 2012-12-26 ザ ペン ステイト リサーチ ファウンデーション 増殖抑制性脂質由来生物活性化合物の全身送達方法およびシステム
JP2007512318A (ja) * 2003-11-25 2007-05-17 プラトコ・テクノロジーズ・（プロプライエタリー）・リミテッド 白金（ｉｉ）錯体並びに該錯体の製法及び使用
EP2011798B1 (de) 2004-09-01 2011-06-29 Platco Technologies (Proprietary) Limited Herstellung von Platin (II)-Komplexen
ES2257178B1 (es) * 2004-09-30 2007-08-16 Universidad Autonoma De Madrid Compuestos de platino de formula trans-(ptc12(isopropilamina)(4-(hidroximetil)-piridina)) y trans-(ptc12(isopropilamina)(3-hidroximetil)-piridina y su aplicacion como farmaco antitumoral.
JP2009525273A (ja) * 2006-01-30 2009-07-09 プラットコー テクノロジーズ （プロプライエタリー） リミテッド 白金（ｉｉ）錯体の調製
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
US9265747B2 (en) 2008-08-26 2016-02-23 Massachusetts Institute Of Technology Platinum (IV) complexes for use in dual mode pharmaceutical therapy
EA201490067A1 (ru) 2011-06-21 2014-05-30 Массачусетс Инститьют Оф Текнолоджи Композиции и способы для лечения рака
AU2012300219A1 (en) * 2011-08-26 2014-03-06 The Regents Of The University Of California Platinum anticancer agents
WO2014160216A2 (en) 2013-03-13 2014-10-02 Massachusetts Institute Of Technology Dual targeting anticancer agents
WO2014165782A2 (en) * 2013-04-05 2014-10-09 Massachusetts Institute Of Technology Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety
CN103360431B (zh) * 2013-07-16 2015-07-01 山西大学 一种以8-氨基喹哪啶为母体的金属配合物及其合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7304882A (de) * 1972-04-10 1973-10-12
DE3777583D1 (de) * 1986-12-18 1992-04-23 Shionogi & Co Ammine-n-heterocyclische platinkomplexe und antitumormittel.
JPS63264492A (ja) * 1986-12-18 1988-11-01 Shionogi & Co Ltd アンミン−脂環系アミン白金錯体および抗腫瘍剤
US4921963A (en) * 1987-04-13 1990-05-01 British Columbia Cancer Foundation Platinum complexes with one radiosensitizing ligand
US5026694A (en) * 1987-04-13 1991-06-25 The British Columbia Cancer Foundation Platinum complexes with one radiosensitizing ligand
GB9502799D0 (en) * 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
CA2497025A1 (en) * 2002-09-11 2004-03-25 Board Of Regents, The University Of Texas System Platinum complexes as antitumor agents in combination with biochemical modulation

Also Published As

Publication number Publication date
IL159993A0 (en) 2004-06-20
CA2456348A1 (en) 2003-03-06
US7122668B2 (en) 2006-10-17
WO2003017998A1 (en) 2003-03-06
JP2005501859A (ja) 2005-01-20
WO2003017998B1 (en) 2003-08-28
EP1420775A1 (de) 2004-05-26
EP1420775B1 (de) 2010-02-17
US20050090478A1 (en) 2005-04-28
ES2339228T3 (es) 2010-05-18
ATE457992T1 (de) 2010-03-15

Similar Documents

Publication Publication Date Title
DE60235375D1 (de) Platinkomplexe und deren verwendung in der therapie
ATE269846T1 (de) N-substituierte aminotetraline als neuropeptid y y5 rezeptor-liganden und ihre anwendung zur behandlung von fettleibigkeit und anderen erkrankungen
TR200103233T2 (tr) Antikolinerjik etkili bileşik ve ß-mimetikler bazında yeni ilaç bileşimleri.
CY1108610T1 (el) Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες
DE60235083D1 (de) Substituierte tetracyclin-verbindungen zur behandlung von malaria
DE60236600D1 (de) Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung
BR0113838A (pt) Derivados de n-fenil-2-pirimidina-amina
PL372809A1 (en) Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof
ATE466085T1 (de) Protease-resistente modifizierte interferon alpha polypeptide
BG108660A (en) Pyrrolidinone derivatives
ATE290529T1 (de) Biphenylderivate, ihre herstellung und ihre verwendung als mtp-inhibitor
TR200200795T2 (tr) 5-HT1B antagonistleri olarak piperazin türevleri
CR6540A (es) Trifluorobutenos nematicidas
DE69834269D1 (de) Piperidinylsubstituierte pyridylalkan-, -alken- und -alkincarbonsäuren als cytostatika und immunsuppressiva
ATE291024T1 (de) Neue 4-aminofuropyrimidine und ihre verwendung
DE60218633D1 (de) Inhibitoren von cruzipain und anderen cysteinproteasen
SE9703414D0 (sv) New compounds
ATE319718T1 (de) Oxazolo- und furopyrimidine und deren verwendung als medikamente gegen tumore
ATE411984T1 (de) Neue kondensierte n-pyrazinyl-sulfonamide und deren verwendung bei der behandlung von chemokinvermittelten krankheiten
DE60103856D1 (de) Thiazolopyrimidine und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität
DK1379508T3 (da) N-(aryl)-2arylethensulfonamider og terapeutiske anvendelser deraf
DE60121804D1 (de) Pharmazeutische zusammensetzung eines biguanin (metformin) und arginin
ATE369348T1 (de) Zyklisierte benzamid-neurokinin-antagonisten zur verwendung in therapie
ATE497967T1 (de) Interzelluläre kommunikation erleichternden verbindungen und deren medizinischen verwendungen
MY136297A (en) Piperazine derivatives having sst1 antagonistic activity

Legal Events

Date Code Title Description
8364 No opposition during term of opposition