ATE319718T1 - Oxazolo- und furopyrimidine und deren verwendung als medikamente gegen tumore - Google Patents

Oxazolo- und furopyrimidine und deren verwendung als medikamente gegen tumore

Info

Publication number
ATE319718T1
ATE319718T1 AT02740590T AT02740590T ATE319718T1 AT E319718 T1 ATE319718 T1 AT E319718T1 AT 02740590 T AT02740590 T AT 02740590T AT 02740590 T AT02740590 T AT 02740590T AT E319718 T1 ATE319718 T1 AT E319718T1
Authority
AT
Austria
Prior art keywords
furopyrimidines
oxazolo
against tumors
medications against
medications
Prior art date
Application number
AT02740590T
Other languages
English (en)
Inventor
Guido Bold
Paul William Manley
Andreas Martin-Kohler
Urs Sequin
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE319718T1 publication Critical patent/ATE319718T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT02740590T 2001-05-14 2002-05-13 Oxazolo- und furopyrimidine und deren verwendung als medikamente gegen tumore ATE319718T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH8732001 2001-05-14

Publications (1)

Publication Number Publication Date
ATE319718T1 true ATE319718T1 (de) 2006-03-15

Family

ID=4544205

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02740590T ATE319718T1 (de) 2001-05-14 2002-05-13 Oxazolo- und furopyrimidine und deren verwendung als medikamente gegen tumore

Country Status (12)

Country Link
US (1) US7294633B2 (de)
EP (1) EP1390371B1 (de)
JP (1) JP4155827B2 (de)
CN (1) CN100378107C (de)
AT (1) ATE319718T1 (de)
BR (1) BR0209645A (de)
CA (1) CA2449188A1 (de)
DE (1) DE60209721T2 (de)
DK (1) DK1390371T3 (de)
ES (1) ES2259707T3 (de)
PT (1) PT1390371E (de)
WO (1) WO2002092603A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007513155A (ja) * 2003-12-04 2007-05-24 スミスクライン ビーチャム コーポレーション 新規化合物
KR20050091462A (ko) * 2004-03-12 2005-09-15 한국과학기술연구원 푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제
EP1731523A4 (de) * 2004-04-01 2009-08-12 Takeda Pharmaceutical Thiazolopyrimidinderivat
US8859581B2 (en) 2005-04-25 2014-10-14 Merck Patent Gmbh Azaheterocyclic compounds as kinase inhibitors
DE102005061170A1 (de) 2005-12-21 2007-07-05 Bayer Healthcare Ag Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung
DE102005061171A1 (de) 2005-12-21 2007-07-05 Bayer Healthcare Ag Neue, cyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung
WO2007148835A1 (ja) * 2006-06-22 2007-12-27 Nippon Chemiphar Co., Ltd. 抗ガン剤耐性克服剤
DE102007019691A1 (de) * 2007-04-26 2008-10-30 Bayer Healthcare Ag Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie
DE102007019690A1 (de) 2007-04-26 2008-10-30 Bayer Healthcare Ag Verwendung von cyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie
DE102007027800A1 (de) 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte bicyclische Heteroaryl-Verbindungen und ihre Verwendung
DE102007027799A1 (de) 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte Furopyrimidine und ihre Verwendung
NZ590377A (en) * 2008-07-15 2011-11-25 Sanofi Aventis Oxazolopyrimidines as edg-1 receptor agonists
UY32240A (es) 2008-11-14 2010-06-30 Boeringer Ingelheim Kg Nuevas 2,4-diaminopirimidinas, sus sales farmacéuticamente aceptables, composiciones conteniéndolas y aplicaciones.
CN101899057A (zh) * 2010-07-21 2010-12-01 中国药科大学 嘧啶并噁唑衍生物的一种制备方法及其在医学上的用途
US8907093B2 (en) * 2011-07-07 2014-12-09 Sanofi Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring
US8580816B2 (en) * 2011-07-07 2013-11-12 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-b]pyridine ring
CN103087077B (zh) * 2011-11-03 2016-05-18 上海希迈医药科技有限公司 噻吩并嘧啶和呋喃并嘧啶类衍生物、其制备方法及其在医药上的应用
CN103360407B (zh) * 2012-04-10 2016-06-22 上海希迈医药科技有限公司 一种噻吩并嘧啶类衍生物、其制备方法及其在医药上的应用
US9868744B2 (en) 2014-04-25 2018-01-16 Pfizer Inc. Heteroaromatic compounds and their use as dopamine D1 ligands
CN104650111A (zh) * 2015-01-14 2015-05-27 中国药科大学 芳基脲及芳基酰胺取代的噁唑并嘧啶类化合物及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137879A (en) 1990-03-30 1992-08-11 Dowelanco Furopyrimidin-4-imine derivatives
US5227387A (en) * 1991-09-03 1993-07-13 Dowelanco Quinoline nematicidal method
EP0682027B1 (de) * 1994-05-03 1997-10-15 Novartis AG Pyrrolopyrimidinderivate mit antiproliferativer Wirkung
JPH1184248A (ja) * 1997-09-12 1999-03-26 Nikon Corp 反射屈折縮小光学系
HU230302B1 (hu) * 2000-10-20 2015-12-28 Eisai R&D Management Co., Ltd. Nitrogéntartalmú aromás származékok és ezeket tartalmazó gyógyászati készítmények

Also Published As

Publication number Publication date
DE60209721D1 (de) 2006-05-04
JP2005508855A (ja) 2005-04-07
US20040152892A1 (en) 2004-08-05
PT1390371E (pt) 2006-07-31
CN100378107C (zh) 2008-04-02
CN1509291A (zh) 2004-06-30
WO2002092603A1 (en) 2002-11-21
DE60209721T2 (de) 2006-09-07
JP4155827B2 (ja) 2008-09-24
US7294633B2 (en) 2007-11-13
ES2259707T3 (es) 2006-10-16
CA2449188A1 (en) 2002-11-21
BR0209645A (pt) 2004-07-06
EP1390371A1 (de) 2004-02-25
DK1390371T3 (da) 2006-06-19
EP1390371B1 (de) 2006-03-08

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