DE60234181D1 - Zwei photonen absorbierende bordipyrromethen-difluorid-farbstoffe und ihre anwendungen - Google Patents

Zwei photonen absorbierende bordipyrromethen-difluorid-farbstoffe und ihre anwendungen

Info

Publication number
DE60234181D1
DE60234181D1 DE60234181T DE60234181T DE60234181D1 DE 60234181 D1 DE60234181 D1 DE 60234181D1 DE 60234181 T DE60234181 T DE 60234181T DE 60234181 T DE60234181 T DE 60234181T DE 60234181 D1 DE60234181 D1 DE 60234181D1
Authority
DE
Germany
Prior art keywords
bordipyrromethene
applications
photon
measuring
laser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60234181T
Other languages
English (en)
Inventor
Niko Meltola
Aleksi Soini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arctic Diagnostics Oy
Original Assignee
Arctic Diagnostics Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20011439A external-priority patent/FI20011439A0/fi
Application filed by Arctic Diagnostics Oy filed Critical Arctic Diagnostics Oy
Application granted granted Critical
Publication of DE60234181D1 publication Critical patent/DE60234181D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60234181T 2001-07-02 2002-07-01 Zwei photonen absorbierende bordipyrromethen-difluorid-farbstoffe und ihre anwendungen Expired - Lifetime DE60234181D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30178801P 2001-07-02 2001-07-02
FI20011439A FI20011439A0 (fi) 2001-07-02 2001-07-02 Kaksi fotonia absorboivat dipyrrometeenibooridifluoridi väriaineet ja niiden käyttö
PCT/FI2002/000586 WO2003005030A1 (en) 2001-07-02 2002-07-01 Two-photon absorbing dipyrrometheneboron difluoride dyes and their applications

Publications (1)

Publication Number Publication Date
DE60234181D1 true DE60234181D1 (de) 2009-12-10

Family

ID=26161195

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60234181T Expired - Lifetime DE60234181D1 (de) 2001-07-02 2002-07-01 Zwei photonen absorbierende bordipyrromethen-difluorid-farbstoffe und ihre anwendungen

Country Status (8)

Country Link
US (1) US7763439B2 (de)
EP (1) EP1402263B1 (de)
JP (1) JP4340149B2 (de)
CN (1) CN1257408C (de)
AT (1) ATE447178T1 (de)
DE (1) DE60234181D1 (de)
RU (1) RU2296333C2 (de)
WO (1) WO2003005030A1 (de)

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FI20040236A0 (fi) 2004-02-13 2004-02-13 Arctic Diagnostics Oy Kaksoisfotoniviritetyn Fluoresenssin käyttö kliinisen kemian analyyttien määrityksissä
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US8054727B2 (en) * 2005-11-08 2011-11-08 Panasonic Corporation Information recording medium and method for manufacturing the same, and optical information recording/reproducing device
JP4748542B2 (ja) 2006-02-24 2011-08-17 古河電気工業株式会社 フローサイトメトリーによる生体分子の定量システム、及び定量方法
AU2007322261B2 (en) * 2006-11-01 2014-01-23 Ventana Medical Systems, Inc. Haptens, hapten conjugates, compositions thereof and method for their preparation and use
AU2015252024B2 (en) * 2006-11-01 2018-02-22 Ventana Medical Systems, Inc. Haptens, hapten conjugates, compositions thereof and method for their preparation and use
KR100870243B1 (ko) 2007-05-25 2008-11-25 고려대학교 산학협력단 세포의 실시간 모니터링용 이광자 염료, 그 제조방법 및이를 이용한 세포의 실시간 모니터링 방법
KR100886722B1 (ko) 2007-05-25 2009-03-04 고려대학교 산학협력단 세포질 내 마그네슘의 실시간 모니터링용 이광자 염료, 그제조방법 및 이를 이용한 세포질 내 마그네슘의 실시간모니터링 방법
KR100908930B1 (ko) 2008-02-12 2009-07-23 한국과학기술원 티에닐을 포함하는 보론-다이피린 화합물, 이의 제조방법및 상기 티에닐을 포함하는 보론-다이피린 화합물이 포함된화학센서
US20120002029A1 (en) * 2010-06-30 2012-01-05 Fluid Imaging Technologies, Inc. System and method for sweeping mirror enhanced imaging flow cytometry
SG190173A1 (en) * 2010-11-24 2013-07-31 Univ Singapore Bodipy structure fluorescence dye for neural stem cell probe
WO2012110945A1 (en) 2011-02-14 2012-08-23 Council Of Scientific & Industrial Research Carbazole end capped bipyridine compounds and process for preparation thereof
KR20140109851A (ko) * 2011-08-02 2014-09-16 유니버시티 오브 써던 캘리포니아 편광 매질 중에서 대칭 파괴 분자내 전하 전달을 수행할 수 있는 화합물, 및 이를 포함하는 유기 광기전력 장치
GB201120924D0 (en) * 2011-12-06 2012-01-18 Johnson Matthey Plc Tracers and method of marking hydrocarbon liquids
CN102875584A (zh) * 2012-10-26 2013-01-16 天津希恩思生化科技有限公司 一种茚烯类化合物及其制备方法
CN103242671B (zh) * 2013-04-28 2014-05-07 商丘师范学院 一种o,o二齿型有机二氟化硼荧光染料及其制备方法
CN103242674B (zh) * 2013-04-28 2014-04-02 孔凯明 一种o,o二齿型有机二氟化硼荧光染料及其制备方法
CN103666456B (zh) * 2013-12-02 2015-02-04 大连理工大学 一类氟化硼络合二吡咯甲川荧光探针,其制备方法及应用
CN104479396B (zh) * 2014-11-20 2016-08-24 河南师范大学 氨基酸类双光子荧光染料
CN105238388B (zh) * 2015-09-21 2017-06-06 遵义师范学院 一种用于细胞内糖链抗原活检的双光子荧光探针、荧标试剂盒以及检测方法
US9983115B2 (en) 2015-09-21 2018-05-29 Fluid Imaging Technologies, Inc. System and method for monitoring particles in a fluid using ratiometric cytometry
KR101968940B1 (ko) * 2015-10-27 2019-04-15 주식회사 엘지화학 화합물 및 이를 포함하는 색변환 필름
CN106632977A (zh) * 2016-12-13 2017-05-10 苏州吉人高新材料股份有限公司 一种具有荧光特性的异氰酸酯固化剂及其制备方法
RU2680090C1 (ru) * 2017-12-12 2019-02-15 ООО "Биотех-Инновации" 2-(4,4-дифтор-1,3,5,7-тетраметил-2,6-дисульфо-4-боро-3а,4а-диаза-s-индацен-8-ил)-бензойная кислота и ее производные, способ их получения и их применение для флуоресцентного мечения белковых молекул
CN112174991B (zh) * 2020-09-23 2023-02-10 复旦大学 近红外区第二窗口激发和发射的荧光染料及其制备方法和应用
CN113912762B (zh) * 2021-09-24 2023-02-10 复旦大学 水溶性的近红外二区大分子荧光探针及其制备方法和应用
CN114315938A (zh) * 2021-11-24 2022-04-12 中国人民解放军联勤保障部队第九六〇医院 一种荧光核酸探针的制备方法及其在rna成像中的应用
CN114890958B (zh) * 2022-02-23 2023-10-20 四川警察学院 双光子染料化合物、其制备方法及其应用

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JP3498960B2 (ja) 1993-09-03 2004-02-23 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 蛍光酸素チャンネリングイムノアッセイ
NZ291154A (en) * 1994-07-25 1997-11-24 Boehringer Mannheim Gmbh Di- or trivalent rare earth or transition metal complexes having three ligands, each of which has at least two nitrogen-containing heterocycles and complexed through nitrogen, and at least one reactive group bound to the ligard(s)
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US6342397B1 (en) * 1998-06-04 2002-01-29 Erkki Soini Homogeneous biospecific assay using a solid phase, two-photon excitation and confocal fluorescence detection
FI981272A (fi) 1998-06-04 1999-12-05 Erkki Juhani Soini Homogeeninen biospesifinen määritysmenetelmä

Also Published As

Publication number Publication date
US7763439B2 (en) 2010-07-27
RU2004102687A (ru) 2005-03-20
CN1526071A (zh) 2004-09-01
WO2003005030A1 (en) 2003-01-16
US20040157231A1 (en) 2004-08-12
RU2296333C2 (ru) 2007-03-27
JP4340149B2 (ja) 2009-10-07
JP2004533626A (ja) 2004-11-04
EP1402263A1 (de) 2004-03-31
CN1257408C (zh) 2006-05-24
ATE447178T1 (de) 2009-11-15
EP1402263B1 (de) 2009-10-28

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