DE60231068D1 - Die Verwendung von 4-Pyridylmethylphthalazinen zur Behandlung von Nierentumoren - Google Patents

Die Verwendung von 4-Pyridylmethylphthalazinen zur Behandlung von Nierentumoren

Info

Publication number
DE60231068D1
DE60231068D1 DE60231068T DE60231068T DE60231068D1 DE 60231068 D1 DE60231068 D1 DE 60231068D1 DE 60231068 T DE60231068 T DE 60231068T DE 60231068 T DE60231068 T DE 60231068T DE 60231068 D1 DE60231068 D1 DE 60231068D1
Authority
DE
Germany
Prior art keywords
pyridylmethylphthalazines
treatment
kidney tumors
phthalazine
pyridylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60231068T
Other languages
English (en)
Inventor
Margaret Han Dugan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE60231068D1 publication Critical patent/DE60231068D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60231068T 2001-09-12 2002-09-11 Die Verwendung von 4-Pyridylmethylphthalazinen zur Behandlung von Nierentumoren Expired - Lifetime DE60231068D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31869401P 2001-09-12 2001-09-12
US33102501P 2001-09-12 2001-09-12
US32204401P 2001-09-14 2001-09-14
US38816302P 2002-06-12 2002-06-12

Publications (1)

Publication Number Publication Date
DE60231068D1 true DE60231068D1 (de) 2009-03-19

Family

ID=27502161

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60212415T Expired - Lifetime DE60212415T2 (de) 2001-09-12 2002-09-11 Die verwendung von einer 4-pyridylmethylphtalazine enthaltenden kombination zur behandlung von tumoren
DE60231068T Expired - Lifetime DE60231068D1 (de) 2001-09-12 2002-09-11 Die Verwendung von 4-Pyridylmethylphthalazinen zur Behandlung von Nierentumoren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60212415T Expired - Lifetime DE60212415T2 (de) 2001-09-12 2002-09-11 Die verwendung von einer 4-pyridylmethylphtalazine enthaltenden kombination zur behandlung von tumoren

Country Status (22)

Country Link
US (2) US20040258770A1 (de)
EP (1) EP1427420B1 (de)
JP (1) JP2005502690A (de)
KR (1) KR20040029172A (de)
CN (1) CN1330308C (de)
AT (2) ATE329597T1 (de)
AU (2) AU2002342678B2 (de)
BR (1) BR0212446A (de)
CA (1) CA2457848A1 (de)
CO (1) CO5560545A2 (de)
CY (1) CY1105189T1 (de)
DE (2) DE60212415T2 (de)
DK (1) DK1427420T3 (de)
ES (2) ES2266590T3 (de)
HR (1) HRP20040241A2 (de)
IL (1) IL160382A0 (de)
NO (1) NO327358B1 (de)
NZ (1) NZ531484A (de)
PL (1) PL367349A1 (de)
PT (1) PT1427420E (de)
RS (1) RS16804A (de)
WO (1) WO2003022282A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0223341D0 (en) * 2002-10-08 2002-11-13 Groningen Acad Ziekenhuis Organic compounds
JP2006514991A (ja) * 2002-12-27 2006-05-18 シエーリング アクチエンゲゼルシャフト 新規医薬組合せ
AU2003233586A1 (en) * 2003-05-20 2005-01-21 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising capecitabine and a liposomal platinum complex
AU2004273615B2 (en) * 2003-09-23 2009-01-15 Novartis Ag Combination of a VEGF receptor inhibitor with a chemotherapeutic agent
GB0610925D0 (en) * 2006-06-02 2006-07-12 Novartis Ag Use of vascular endothelial growth factor receptor inhibitors for the treatment of cancer
KR101037292B1 (ko) * 2010-09-03 2011-05-27 (주)슈추어 신발 장식구

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE267174T1 (de) * 1994-08-09 2004-06-15 Eisai Co Ltd Kondensierte pyridazinverbindungen
KR100489174B1 (ko) * 1996-03-05 2005-09-30 제네카-파마 소시에떼아노님 4-아닐리노퀴나졸린유도체
US6096904A (en) * 1996-12-03 2000-08-01 The Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion

Also Published As

Publication number Publication date
CN1553803A (zh) 2004-12-08
AU2006203428A1 (en) 2006-08-31
IL160382A0 (en) 2004-07-25
JP2005502690A (ja) 2005-01-27
PT1427420E (pt) 2006-10-31
NZ531484A (en) 2007-02-23
ATE329597T1 (de) 2006-07-15
PL367349A1 (en) 2005-02-21
NO327358B1 (no) 2009-06-15
CA2457848A1 (en) 2003-03-20
RS16804A (en) 2007-02-05
HRP20040241A2 (en) 2005-04-30
KR20040029172A (ko) 2004-04-03
DE60212415T2 (de) 2006-11-23
DK1427420T3 (da) 2006-10-02
NO20040973L (no) 2004-06-03
DE60212415D1 (de) 2006-07-27
ES2320922T3 (es) 2009-05-29
EP1427420A1 (de) 2004-06-16
US20090196871A1 (en) 2009-08-06
BR0212446A (pt) 2004-08-17
CN1330308C (zh) 2007-08-08
US20040258770A1 (en) 2004-12-23
WO2003022282A1 (en) 2003-03-20
AU2002342678B2 (en) 2006-08-24
ES2266590T3 (es) 2007-03-01
CY1105189T1 (el) 2010-03-03
AU2006203428B2 (en) 2009-06-04
CO5560545A2 (es) 2005-09-30
ATE421880T1 (de) 2009-02-15
EP1427420B1 (de) 2006-06-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN