DE60230677D1 - Verfahren und materialien zur herstellung organischer produkte in zellen von candida-spezies - Google Patents

Verfahren und materialien zur herstellung organischer produkte in zellen von candida-spezies

Info

Publication number
DE60230677D1
DE60230677D1 DE60230677T DE60230677T DE60230677D1 DE 60230677 D1 DE60230677 D1 DE 60230677D1 DE 60230677 T DE60230677 T DE 60230677T DE 60230677 T DE60230677 T DE 60230677T DE 60230677 D1 DE60230677 D1 DE 60230677D1
Authority
DE
Germany
Prior art keywords
cells
organic products
materials
producing organic
candida species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60230677T
Other languages
English (en)
Inventor
Vineet Rajgarhia
Merja Penttilae
Laura Ruohonen
Marja Ilmen
Kari Koivuranta
Pirkko Suominen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cargill Inc
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2001/044041 external-priority patent/WO2002042471A2/en
Application filed by Cargill Inc filed Critical Cargill Inc
Application granted granted Critical
Publication of DE60230677D1 publication Critical patent/DE60230677D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
DE60230677T 2001-11-23 2002-05-23 Verfahren und materialien zur herstellung organischer produkte in zellen von candida-spezies Expired - Fee Related DE60230677D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2001/044041 WO2002042471A2 (en) 2000-11-22 2001-11-23 Methods and materials for the synthesis of organic products
US09/992,430 US7109010B2 (en) 2000-11-22 2001-11-23 Methods and materials for the synthesis of organic products
PCT/US2002/016223 WO2003049525A2 (en) 2001-11-23 2002-05-23 Methods and materials for the production of organic products in cells of $i(candida) species

Publications (1)

Publication Number Publication Date
DE60230677D1 true DE60230677D1 (de) 2009-02-12

Family

ID=26680605

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230677T Expired - Fee Related DE60230677D1 (de) 2001-11-23 2002-05-23 Verfahren und materialien zur herstellung organischer produkte in zellen von candida-spezies

Country Status (11)

Country Link
EP (1) EP1474507B1 (de)
JP (1) JP4649109B2 (de)
CN (1) CN100402644C (de)
AT (1) ATE419336T1 (de)
AU (1) AU2002311989A1 (de)
BR (1) BRPI0214366B1 (de)
CA (1) CA2474152A1 (de)
DE (1) DE60230677D1 (de)
DK (1) DK1474507T3 (de)
ES (1) ES2318016T3 (de)
WO (1) WO2003049525A2 (de)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
DK2301949T3 (en) 2003-05-02 2015-07-20 Cargill Inc Genetically modified yeast species and fermentation methods using genetically modified yeast
KR20080028902A (ko) * 2005-06-02 2008-04-02 카아길, 인코포레이팃드 이싸첸키아 오리엔탈리스에 속하는 종 및 그와 밀접한관련이 있는 종의 유전자 변형된 효모 및 이를 이용한 발효방법
EP1929009A2 (de) 2005-09-22 2008-06-11 Tate & Lyle Ingredients Americas, Inc. Verbesserte stämme zur herstellung organischer säuren
EP1960516B1 (de) * 2005-11-23 2012-12-26 Cargill, Incorporated Milchsäure produzierende hefezellen mit nicht funktionellem l- oder d-lactat: ferricytochrom-c-oxidoreduktase-gen:
CA2645361A1 (en) 2006-03-13 2007-09-20 Cargill Inc. Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol
KR20090127868A (ko) 2006-12-07 2009-12-14 메사추세츠 인스티튜트 오브 테크놀로지 광역 전사 기구 조작
ES2616428T3 (es) * 2007-12-07 2017-06-13 Toray Industries, Inc. Casete de expresión para lactasa deshidrogenasa, levadura transformada y método para producir ácido láctico
EP2316961A4 (de) 2008-06-30 2012-04-25 Toyota Motor Co Ltd Verfahren zur herstellung organischer säure
WO2010095751A1 (ja) * 2009-02-23 2010-08-26 キリンホールディングス株式会社 キャンディダ・ユティリスによる高効率乳酸製造法
JPWO2010095750A1 (ja) * 2009-02-23 2012-08-30 キリンホールディングス株式会社 キシロースを炭素源として使用しうる、キャンディダ・ユティリスによる物質の製造法
NZ600585A (en) * 2009-12-29 2014-07-25 Butamax Tm Advanced Biofuels Expression of hexose kinase in recombinant host cells
WO2012071470A2 (en) 2010-11-22 2012-05-31 Cargill, Incorporated Compositions and methods for increased ethanol titer from biomass
BR112013012630B1 (pt) 2010-11-22 2021-09-08 Novozymes, Inc. Célula de levedura geneticamente modificada, e, método para produzir 3-hp
US9605285B2 (en) 2011-01-25 2017-03-28 Cargill, Incorporated Compositions and methods for succinate production
BR112013026193A2 (pt) 2011-04-11 2020-11-10 Cargill, Incorporated composições e métodos para a produção aumentada de etanol a partir de biomassa
JP5858463B2 (ja) * 2011-10-26 2016-02-10 三井造船株式会社 乳酸生産菌
CN103103137B (zh) * 2012-05-17 2015-04-29 西安交通大学 一种解淀粉产乳酸固氮的酵母菌及其应用
BR112015001601A2 (pt) 2012-07-25 2017-11-07 Bioamber Sas células de levedura tendo curso de tca redutor de piruvato em succinato e superexpressão de uma enzima transidrogenase nad(p)+ exógena
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
CA2891130A1 (en) 2012-11-30 2014-06-05 Novozymes, Inc. 3-hydroxypropionic acid production by recombinant yeasts
WO2015017721A1 (en) 2013-07-31 2015-02-05 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
JP6499587B2 (ja) * 2013-11-22 2019-04-10 Ｊｍｔｃエンザイム株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
CN107075452A (zh) * 2014-07-25 2017-08-18 诺沃吉股份有限公司 来源于解脂耶氏酵母和解腺嘌呤阿氏酵母的启动子及其使用方法
EP3303375A1 (de) 2015-06-04 2018-04-11 BioAmber Inc. Biobasierte herstellung von funktionalisierten alpha-substituierten acrylaten und c4-dicarboxylaten
EP3341475A1 (de) 2015-08-24 2018-07-04 Novozymes A/S Beta-alanin-aminotransferasen zur herstellung von 3-hydroxypropionsäure
CA3030605A1 (en) 2016-07-13 2018-01-18 Dsm Ip Assets B.V. Malate dehyrogenases
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
US11718820B2 (en) 2017-08-17 2023-08-08 Cargill, Incorporated Genetically modified haploid Issatchenkia orientalis
CN112074606A (zh) * 2018-02-16 2020-12-11 Ptt全球化学股份有限公司 用于乳酸生产的微生物和工艺
EP3775247A4 (de) * 2018-04-13 2021-12-15 Lygos, Inc. Rekombinante wirtszellen und verfahren zur herstellung von l-milchsäure
FI20195716A1 (en) * 2019-08-30 2021-03-01 Finnfoam Oy Genetically modified fungi and related methods and uses

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI913197A0 (fi) * 1991-07-01 1991-07-01 Xyrofin Oy Nya jaeststammar med reducerad foermaoga att metabolisera xylitol, foerfarande foer bildande av dessa och deras anvaendning vid framstaellning av xylitol.
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
EP0875579B1 (de) * 1997-05-03 2007-06-27 Societe Des Produits Nestle S.A. Herstellung von L(+)-Lactat
IL136407A0 (en) * 1997-12-02 2001-06-14 Du Pont Method for the production of glycerol by recombinant organisms
US6432686B1 (en) * 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
AU780135B2 (en) * 1999-05-21 2005-03-03 Cargill Inc. Methods and materials for the synthesis of organic products
US6268189B1 (en) * 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
EP1339852A2 (de) * 2000-11-22 2003-09-03 Cargill Dow LLC Methode und materiale für das synthese von organische produkte

Also Published As

Publication number Publication date
AU2002311989A1 (en) 2003-06-23
BR0214366A (pt) 2006-05-23
DK1474507T3 (da) 2009-04-06
WO2003049525A2 (en) 2003-06-19
EP1474507A2 (de) 2004-11-10
CN100402644C (zh) 2008-07-16
AU2002311989A8 (en) 2003-06-23
EP1474507B1 (de) 2008-12-31
CA2474152A1 (en) 2003-06-19
JP2005518197A (ja) 2005-06-23
JP4649109B2 (ja) 2011-03-09
ES2318016T3 (es) 2009-05-01
CN1628168A (zh) 2005-06-15
ATE419336T1 (de) 2009-01-15
WO2003049525A3 (en) 2004-08-26
BRPI0214366B1 (pt) 2016-03-22
EP1474507A4 (de) 2005-09-21

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee