DE60221009D1 - Biologisch abbaubare copolymere, die an ein segment mit mehreren funktionellen gruppen gebunden sind - Google Patents
Biologisch abbaubare copolymere, die an ein segment mit mehreren funktionellen gruppen gebunden sindInfo
- Publication number
- DE60221009D1 DE60221009D1 DE60221009T DE60221009T DE60221009D1 DE 60221009 D1 DE60221009 D1 DE 60221009D1 DE 60221009 T DE60221009 T DE 60221009T DE 60221009 T DE60221009 T DE 60221009T DE 60221009 D1 DE60221009 D1 DE 60221009D1
- Authority
- DE
- Germany
- Prior art keywords
- functional groups
- segment
- multiple functional
- moiety
- biodegradable copolymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001577 copolymer Polymers 0.000 title abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- YLFIGGHWWPSIEG-UHFFFAOYSA-N aminoxyl Chemical group [O]N YLFIGGHWWPSIEG-UHFFFAOYSA-N 0.000 abstract 1
- 229920002988 biodegradable polymer Polymers 0.000 abstract 1
- 239000004621 biodegradable polymer Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28880601P | 2001-05-07 | 2001-05-07 | |
US288806P | 2001-05-07 | ||
PCT/US2002/006642 WO2002090417A1 (en) | 2001-05-07 | 2002-03-20 | Biodegradable copolymers linked to segment with a plurality of functional groups |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60221009D1 true DE60221009D1 (de) | 2007-08-16 |
DE60221009T2 DE60221009T2 (de) | 2008-03-13 |
Family
ID=23108719
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60221009T Expired - Lifetime DE60221009T2 (de) | 2001-05-07 | 2002-03-20 | Biologisch abbaubare copolymere, die an ein segment mit mehreren funktionellen gruppen gebunden sind |
DE0001392751T Pending DE02717541T1 (de) | 2001-05-07 | 2002-03-20 | Biologisch abbaubare copolymere, die an ein segment mit mehreren funktionellen gruppen gebunden sind |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE0001392751T Pending DE02717541T1 (de) | 2001-05-07 | 2002-03-20 | Biologisch abbaubare copolymere, die an ein segment mit mehreren funktionellen gruppen gebunden sind |
Country Status (9)
Country | Link |
---|---|
US (1) | US6830747B2 (de) |
EP (1) | EP1392751B1 (de) |
JP (1) | JP4391750B2 (de) |
AT (1) | ATE366270T1 (de) |
AU (1) | AU2002248535B2 (de) |
CA (1) | CA2440394C (de) |
DE (2) | DE60221009T2 (de) |
ES (1) | ES2220247T3 (de) |
WO (1) | WO2002090417A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
EP1334990A1 (de) * | 2002-02-06 | 2003-08-13 | Polyganics B.V. | DL-Lactide-epsilon-caprolactone Copolymere |
US20050163821A1 (en) * | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
AU2004215898A1 (en) * | 2003-02-26 | 2004-09-10 | Medivas, Llc | Bioactive stents and methods for use thereof |
US9198887B2 (en) | 2003-09-15 | 2015-12-01 | Nanopharmaceuticals Llc | Thyroid hormone analogs and methods of use |
CA2539288C (en) | 2003-09-15 | 2015-05-12 | Shaker A. Mousa | Thyroid hormone analogs and methods of use |
US8668926B1 (en) | 2003-09-15 | 2014-03-11 | Shaker A. Mousa | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof |
US20060024357A1 (en) * | 2004-05-12 | 2006-02-02 | Medivas, Llc | Wound healing polymer compositions and methods for use thereof |
US20060188486A1 (en) * | 2003-10-14 | 2006-08-24 | Medivas, Llc | Wound care polymer compositions and methods for use thereof |
US8603634B2 (en) * | 2004-10-27 | 2013-12-10 | Abbott Cardiovascular Systems Inc. | End-capped poly(ester amide) copolymers |
US20060089485A1 (en) * | 2004-10-27 | 2006-04-27 | Desnoyer Jessica R | End-capped poly(ester amide) copolymers |
US8007775B2 (en) | 2004-12-30 | 2011-08-30 | Advanced Cardiovascular Systems, Inc. | Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same |
US8057543B2 (en) * | 2005-01-28 | 2011-11-15 | Greatbatch Ltd. | Stent coating for eluting medication |
US10130686B2 (en) | 2005-09-15 | 2018-11-20 | Nanopharmaceuticals Llc | Method and composition of thyroid hormone analogues and nanoformulations thereof for treating inflammatory disorders |
US9498536B2 (en) | 2005-09-15 | 2016-11-22 | Nanopharmaceuticals Llc | Method and composition of thyroid hormone analogues and nanoformulations thereof for treating anti-inflammatory disorders |
US9220788B2 (en) | 2009-06-17 | 2015-12-29 | Nanopharmaceuticals Llc | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof |
US20100209382A1 (en) | 2005-09-16 | 2010-08-19 | Ordway Research Institute, Inc. | Polyphenol Conjugates as RGD-Binding Compounds and Methods of Use |
EP1933881B1 (de) | 2005-09-22 | 2019-03-13 | Medivas, LLC | Feste polymer-abgabezusammensetzungen und anwendungsverfahren dafür |
CA2623198C (en) | 2005-09-22 | 2014-08-05 | Medivas, Llc | Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use |
US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
EP1917971A1 (de) * | 2006-10-27 | 2008-05-07 | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) | Zusammensetzungen mit verlängerter Wirkstofffreigabe, enthaltend Polymere mit sehr niedrigem Molekulargewicht |
AU2007353426A1 (en) * | 2006-12-22 | 2008-11-20 | Albany College Of Pharmacy And Health Sciences | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof |
CA2686068A1 (en) * | 2007-05-14 | 2008-11-20 | Tyco Healthcare Group Lp | Biodegradable peptide releasing polymers |
WO2010120506A1 (en) | 2009-03-31 | 2010-10-21 | Ordway Research Institute, Inc. | Combination treatment of cancer with cetuximab and tetrac |
US8927004B1 (en) | 2014-06-11 | 2015-01-06 | Silver Bullet Therapeutics, Inc. | Bioabsorbable substrates and systems that controllably release antimicrobial metal ions |
US9821094B2 (en) | 2014-06-11 | 2017-11-21 | Silver Bullet Therapeutics, Inc. | Coatings for the controllable release of antimicrobial metal ions |
US9114197B1 (en) | 2014-06-11 | 2015-08-25 | Silver Bullett Therapeutics, Inc. | Coatings for the controllable release of antimicrobial metal ions |
US10265435B2 (en) | 2009-08-27 | 2019-04-23 | Silver Bullet Therapeutics, Inc. | Bone implant and systems and coatings for the controllable release of antimicrobial metal ions |
US8771323B2 (en) | 2010-11-12 | 2014-07-08 | Silver Bullet Therapeutics, Inc. | Bone implant and systems that controllably releases silver |
EP2470257B1 (de) | 2009-08-27 | 2015-03-04 | Silver Bullet Therapeutics Inc. | Knochenimplantate zur Behandlung einer Infektion |
US9314551B2 (en) * | 2010-05-14 | 2016-04-19 | Boston Scientific Scimed, Inc. | Block copolymer-coated endoprosthesis |
US20120189860A1 (en) * | 2011-01-24 | 2012-07-26 | Fina Technology, Inc. | Polymeric compositions comprising polylactic acid oligomers and methods of making the same |
US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
EP2723800B1 (de) | 2011-06-23 | 2015-10-07 | DSM IP Assets B.V. | Mikro- oder nanopartikel mit einem biologisch abbaubaren polyesteramid-copolymer zur verwendung bei der verabreichung von bioaktiven substanzen |
US10538864B2 (en) | 2012-10-24 | 2020-01-21 | Dsm Ip Assets, B.V. | Fibers comprising polyesteramide copolymers for drug delivery |
JP6016577B2 (ja) * | 2012-10-24 | 2016-10-26 | 大阪瓦斯株式会社 | ポリ乳酸含有ブロック共重合体グラフトポリロタキサン及び該ブロック共重合体グラフトポリロタキサンを含有する樹脂組成物 |
WO2015074050A1 (en) | 2013-11-18 | 2015-05-21 | Nanopharmaceuticals Llc | Methods for screening patients for resistance to angioinhibition, treatment and prophylaxis thereof |
US10293044B2 (en) | 2014-04-18 | 2019-05-21 | Auburn University | Particulate formulations for improving feed conversion rate in a subject |
WO2015160501A1 (en) | 2014-04-18 | 2015-10-22 | Auburn University | Particulate vaccine formulations for inducing innate and adaptive immunity |
US9452242B2 (en) | 2014-06-11 | 2016-09-27 | Silver Bullet Therapeutics, Inc. | Enhancement of antimicrobial silver, silver coatings, or silver platings |
US10434071B2 (en) | 2014-12-18 | 2019-10-08 | Dsm Ip Assets, B.V. | Drug delivery system for delivery of acid sensitivity drugs |
US10583199B2 (en) | 2016-04-26 | 2020-03-10 | Northwestern University | Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs |
EP3463477A4 (de) | 2016-06-07 | 2020-03-04 | NanoPharmaceuticals LLC | Mit avss3-integrin-schilddrüsenhormon-antagonisten konjugiertes nicht-spaltbares polymer |
US11351137B2 (en) | 2018-04-11 | 2022-06-07 | Nanopharmaceuticals Llc | Composition and method for dual targeting in treatment of neuroendocrine tumors |
US10328043B1 (en) | 2018-04-11 | 2019-06-25 | Nanopharmaceuticals, Llc. | Composition and method for dual targeting in treatment of neuroendocrine tumors |
US10961204B1 (en) | 2020-04-29 | 2021-03-30 | Nanopharmaceuticals Llc | Composition of scalable thyrointegrin antagonists with improved blood brain barrier penetration and retention into brain tumors |
US11723888B2 (en) | 2021-12-09 | 2023-08-15 | Nanopharmaceuticals Llc | Polymer conjugated thyrointegrin antagonists |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4132735A (en) * | 1975-06-27 | 1979-01-02 | Lever Brothers Company | Detergent compositions |
JPS56157422A (en) * | 1980-05-07 | 1981-12-04 | Mitsui Toatsu Chem Inc | Acetylated polyglycolic acid and preparation thereof |
US4757128A (en) * | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
US4789724A (en) * | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
US4999417A (en) * | 1989-03-30 | 1991-03-12 | Nova Pharmaceutical Corporation | Biodegradable polymer compositions |
FR2707653B1 (fr) * | 1993-07-16 | 1995-09-15 | Vetoquinol Sa | Conjugué entre un polymère biocompatible et biodégradable et une molécule notamment une molécule biologiquement active, à hydrogène mobile, son procédé de préparation et composition pharmaceutique comprenant ce conjugué. |
JP3367577B2 (ja) * | 1994-05-24 | 2003-01-14 | 東洋紡績株式会社 | 酸末端封鎖ポリ乳酸 |
JP3490171B2 (ja) * | 1994-02-21 | 2004-01-26 | 武田薬品工業株式会社 | 生体内分解性ポリマーの末端カルボキシル基におけるエステル |
JP3524195B2 (ja) * | 1994-02-21 | 2004-05-10 | 武田薬品工業株式会社 | 徐放性製剤用基剤 |
US5629384A (en) * | 1994-05-17 | 1997-05-13 | Consiglio Nazionale Delle Ricerche | Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces |
US5516881A (en) * | 1994-08-10 | 1996-05-14 | Cornell Research Foundation, Inc. | Aminoxyl-containing radical spin labeling in polymers and copolymers |
ATE196486T1 (de) * | 1994-08-10 | 2000-10-15 | Peter Neuenschwander | Biokompatibles blockcopolymer |
US5485496A (en) * | 1994-09-22 | 1996-01-16 | Cornell Research Foundation, Inc. | Gamma irradiation sterilizing of biomaterial medical devices or products, with improved degradation and mechanical properties |
US5610241A (en) * | 1996-05-07 | 1997-03-11 | Cornell Research Foundation, Inc. | Reactive graft polymer with biodegradable polymer backbone and method for preparing reactive biodegradable polymers |
ATE357260T1 (de) * | 1998-11-02 | 2007-04-15 | Sod Conseils Rech Applic | Lactongruppen tragende absorbierbare polymere |
EP1135165A1 (de) * | 1998-12-03 | 2001-09-26 | Boston Scientific Limited | Dilatator beschichtet mit arzneistoffkristallen |
CN1339964A (zh) * | 1999-02-19 | 2002-03-13 | 生化研究股份公司 | 用以生产微胶囊的生物可降解复合材料 |
US6503538B1 (en) | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
-
2002
- 2002-03-20 ES ES02717541T patent/ES2220247T3/es not_active Expired - Lifetime
- 2002-03-20 DE DE60221009T patent/DE60221009T2/de not_active Expired - Lifetime
- 2002-03-20 EP EP02717541A patent/EP1392751B1/de not_active Expired - Lifetime
- 2002-03-20 AU AU2002248535A patent/AU2002248535B2/en not_active Ceased
- 2002-03-20 WO PCT/US2002/006642 patent/WO2002090417A1/en active IP Right Grant
- 2002-03-20 CA CA2440394A patent/CA2440394C/en not_active Expired - Fee Related
- 2002-03-20 DE DE0001392751T patent/DE02717541T1/de active Pending
- 2002-03-20 US US10/101,408 patent/US6830747B2/en not_active Expired - Lifetime
- 2002-03-20 JP JP2002587491A patent/JP4391750B2/ja not_active Expired - Fee Related
- 2002-03-20 AT AT02717541T patent/ATE366270T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1392751A4 (de) | 2005-01-26 |
JP4391750B2 (ja) | 2009-12-24 |
ES2220247T3 (es) | 2007-11-16 |
EP1392751A1 (de) | 2004-03-03 |
ES2220247T1 (es) | 2004-12-16 |
JP2004526043A (ja) | 2004-08-26 |
AU2002248535B2 (en) | 2006-06-08 |
ATE366270T1 (de) | 2007-07-15 |
DE02717541T1 (de) | 2004-08-26 |
CA2440394C (en) | 2011-10-04 |
EP1392751B1 (de) | 2007-07-04 |
US20030027940A1 (en) | 2003-02-06 |
CA2440394A1 (en) | 2002-11-14 |
WO2002090417A1 (en) | 2002-11-14 |
US6830747B2 (en) | 2004-12-14 |
DE60221009T2 (de) | 2008-03-13 |
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