DE60215824D1 - Fluorierte nukleophile substitution von alkoholen und reagenzien zur durchführung des verfahrens - Google Patents

Fluorierte nukleophile substitution von alkoholen und reagenzien zur durchführung des verfahrens

Info

Publication number
DE60215824D1
DE60215824D1 DE60215824T DE60215824T DE60215824D1 DE 60215824 D1 DE60215824 D1 DE 60215824D1 DE 60215824 T DE60215824 T DE 60215824T DE 60215824 T DE60215824 T DE 60215824T DE 60215824 D1 DE60215824 D1 DE 60215824D1
Authority
DE
Germany
Prior art keywords
group
independently
fluorinated
azodicarboxylate
hydrofluoroalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60215824T
Other languages
English (en)
Other versions
DE60215824T2 (de
Inventor
P Curran
Sivaraman Dandapani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Application granted granted Critical
Publication of DE60215824D1 publication Critical patent/DE60215824D1/de
Publication of DE60215824T2 publication Critical patent/DE60215824T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/12—Formation or introduction of functional groups containing oxygen of carboxylic acid ester groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02—Compounds containing any of the groups, e.g. carbazates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/20—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group the two nitrogen atoms of the functional groups being doubly-bound to each other, e.g. azoformamide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60215824T 2001-08-20 2002-08-15 Fluorierte nukleophile substitution von alkoholen und reagenzien zur durchführung des verfahrens Expired - Fee Related DE60215824T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US932903 2001-08-20
US09/932,903 US6806357B1 (en) 2001-08-20 2001-08-20 Fluorous nucleophilic substitution of alcohols and reagents for use therein
PCT/US2002/026045 WO2003016246A1 (en) 2001-08-20 2002-08-15 Fluorous nucleophilic substitution of alcohols and reagents for use therein

Publications (2)

Publication Number Publication Date
DE60215824D1 true DE60215824D1 (de) 2006-12-14
DE60215824T2 DE60215824T2 (de) 2007-03-01

Family

ID=25463133

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60215824T Expired - Fee Related DE60215824T2 (de) 2001-08-20 2002-08-15 Fluorierte nukleophile substitution von alkoholen und reagenzien zur durchführung des verfahrens

Country Status (6)

Country Link
US (1) US6806357B1 (de)
EP (1) EP1419126B1 (de)
JP (1) JP4242764B2 (de)
AT (1) ATE344222T1 (de)
DE (1) DE60215824T2 (de)
WO (1) WO2003016246A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6749756B1 (en) * 2000-02-18 2004-06-15 University Of Pittsburgh Reaction and separation methods
US6806357B1 (en) 2001-08-20 2004-10-19 University Of Pittsburgh Fluorous nucleophilic substitution of alcohols and reagents for use therein
US7060850B2 (en) * 2002-07-11 2006-06-13 Fluorous Technologies Incorporated Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
US7364908B2 (en) * 2004-06-17 2008-04-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Separation of fluorous compounds
US20060094866A1 (en) * 2004-11-02 2006-05-04 Gladysz John A Methods, processes and materials for dispensing and recovering supported fluorous reaction components
CN101405240B (zh) 2006-03-24 2012-07-25 日商·Jitsubo株式会社 有机合成用试剂、以及使用该试剂的有机合成反应方法
JP4094654B1 (ja) * 2007-01-31 2008-06-04 東洋化成工業株式会社 アゾジカルボン酸ビス（２−アルコキシエチル）エステル化合物、その製造中間体
CN102516154B (zh) * 2008-09-19 2015-03-18 苏州泽璟生物制药有限公司 氘代的ω-二苯基脲及衍生物以及包含该化合物的药物组合物
CN102190587B (zh) * 2010-03-18 2015-03-04 苏州泽璟生物制药有限公司 氘代甲胺及其盐的合成及生产的方法和工艺
CN106117111B (zh) * 2016-06-26 2018-07-24 仪征市海帆化工有限公司 N-甲基酞酰亚胺的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5463082A (en) 1993-07-08 1995-10-31 Exxon Research And Engineering Company Fluorous multiphase systems
AU731387B2 (en) * 1996-03-20 2001-03-29 Scripps Research Institute, The Azatide peptidomimetics
US5777121A (en) 1996-06-28 1998-07-07 University Of Pittsburgh Fluorous reaction systems
AU3581897A (en) 1996-06-28 1998-01-21 University Of Pittsburgh Fluorous reaction and separation systems
US6806357B1 (en) 2001-08-20 2004-10-19 University Of Pittsburgh Fluorous nucleophilic substitution of alcohols and reagents for use therein

Also Published As

Publication number Publication date
DE60215824T2 (de) 2007-03-01
JP2005508890A (ja) 2005-04-07
WO2003016246A1 (en) 2003-02-27
ATE344222T1 (de) 2006-11-15
JP4242764B2 (ja) 2009-03-25
EP1419126A1 (de) 2004-05-19
EP1419126B1 (de) 2006-11-02
US6806357B1 (en) 2004-10-19

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee