DE60210430D1 - 2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung - Google Patents

2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung

Info

Publication number
DE60210430D1
DE60210430D1 DE60210430T DE60210430T DE60210430D1 DE 60210430 D1 DE60210430 D1 DE 60210430D1 DE 60210430 T DE60210430 T DE 60210430T DE 60210430 T DE60210430 T DE 60210430T DE 60210430 D1 DE60210430 D1 DE 60210430D1
Authority
DE
Germany
Prior art keywords
bromomethyl
preparation
methylbenzoic acid
acid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60210430T
Other languages
English (en)
Other versions
DE60210430T2 (de
Inventor
Paolo Farina
Maurizia Guidetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Archimica SpA
Original Assignee
Prime European Therapeuticals SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prime European Therapeuticals SpA filed Critical Prime European Therapeuticals SpA
Application granted granted Critical
Publication of DE60210430D1 publication Critical patent/DE60210430D1/de
Publication of DE60210430T2 publication Critical patent/DE60210430T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/70—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60210430T 2002-06-21 2002-06-21 2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung Expired - Lifetime DE60210430T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02013800A EP1375467B1 (de) 2002-06-21 2002-06-21 2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
DE60210430D1 true DE60210430D1 (de) 2006-05-18
DE60210430T2 DE60210430T2 (de) 2006-11-30

Family

ID=29716815

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60210430T Expired - Lifetime DE60210430T2 (de) 2002-06-21 2002-06-21 2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung
DE0001375467T Pending DE02013800T1 (de) 2002-06-21 2002-06-21 2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0001375467T Pending DE02013800T1 (de) 2002-06-21 2002-06-21 2-Bromomethyl-6-methyl-benzoesäure und Verfahren zu ihrer Herstellung

Country Status (6)

Country Link
US (1) US6689891B2 (de)
EP (1) EP1375467B1 (de)
AT (1) ATE322472T1 (de)
DE (2) DE60210430T2 (de)
DK (1) DK1375467T3 (de)
ES (1) ES2261556T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109796338B (zh) * 2019-01-15 2022-05-06 深圳市第二人民医院 奥扎格雷中间体对溴甲基肉桂酸酯的合成方法
CN114276210A (zh) * 2021-12-31 2022-04-05 上海合全药业股份有限公司 一种连续制备甲苯衍生物的一溴代物的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806584D0 (en) * 1988-03-19 1988-04-20 Interox Chemicals Ltd Bromination
DE19531164A1 (de) * 1995-08-24 1997-02-27 Hoechst Ag Verfahren zur Herstellung von 4-Brommethyl-3-methoxybenzoesäure-estern
DE19732693C1 (de) * 1997-07-30 1999-03-11 Basf Ag Verfahren zur Herstellung von substituierten Benzylbromiden
ES2287016T3 (es) * 1999-04-28 2007-12-16 Sanofi-Aventis Deutschland Gmbh Derivados de diaril-acido como ligandos del receptor ppar.

Also Published As

Publication number Publication date
ATE322472T1 (de) 2006-04-15
EP1375467B1 (de) 2006-04-05
EP1375467A1 (de) 2004-01-02
US6689891B2 (en) 2004-02-10
ES2261556T3 (es) 2006-11-16
DE60210430T2 (de) 2006-11-30
DK1375467T3 (da) 2006-07-31
DE02013800T1 (de) 2004-07-15
US20030236431A1 (en) 2003-12-25

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Legal Events

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8364 No opposition during term of opposition