DE602007010734D1 - Hydratformen von amg706 - Google Patents

Hydratformen von amg706

Info

Publication number
DE602007010734D1
DE602007010734D1 DE602007010734T DE602007010734T DE602007010734D1 DE 602007010734 D1 DE602007010734 D1 DE 602007010734D1 DE 602007010734 T DE602007010734 T DE 602007010734T DE 602007010734 T DE602007010734 T DE 602007010734T DE 602007010734 D1 DE602007010734 D1 DE 602007010734D1
Authority
DE
Germany
Prior art keywords
amg
amg706
angiogenic
drug substance
phosphate dihydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007010734T
Other languages
English (en)
Inventor
Gonzalo Alva
Seshadri Neervannan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE602007010734D1 publication Critical patent/DE602007010734D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Lubricants (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE602007010734T 2006-02-10 2007-01-26 Hydratformen von amg706 Active DE602007010734D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77239706P 2006-02-10 2006-02-10
PCT/US2007/002182 WO2007092178A1 (en) 2006-02-10 2007-01-26 Hydrate forms of amg706

Publications (1)

Publication Number Publication Date
DE602007010734D1 true DE602007010734D1 (de) 2011-01-05

Family

ID=38003498

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007010734T Active DE602007010734D1 (de) 2006-02-10 2007-01-26 Hydratformen von amg706

Country Status (9)

Country Link
US (1) US7989631B2 (de)
EP (1) EP1987023B1 (de)
JP (2) JP2009526050A (de)
AT (1) ATE489380T1 (de)
AU (1) AU2007212696B2 (de)
CA (1) CA2641713C (de)
DE (1) DE602007010734D1 (de)
ES (1) ES2353482T3 (de)
WO (1) WO2007092178A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1987023B1 (de) * 2006-02-10 2010-11-24 Amgen, Inc Hydratformen von amg706
JP5699075B2 (ja) * 2008-05-14 2015-04-08 アムジエン・インコーポレーテツド 癌の治療のためのｖｅｇｆ（ｒ）阻害剤および肝細胞増殖因子（ｃ−ｍｅｔ）阻害剤との組合せ
WO2013022801A1 (en) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
AU2015301054B2 (en) 2014-08-08 2020-05-14 Forsight Vision4, Inc. Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797388A (en) * 1984-05-21 1989-01-10 Cetus Corporation Pharmaceutical compositions with galactitol as carrier
JP2762522B2 (ja) 1989-03-06 1998-06-04 藤沢薬品工業株式会社 血管新生阻害剤
US5112946A (en) 1989-07-06 1992-05-12 Repligen Corporation Modified pf4 compositions and methods of use
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
USRE39706E1 (en) * 1993-01-15 2007-06-26 Leo Pharma A/S Crystalline form of a vitamin D analogue
US5700823A (en) 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
DE19534177A1 (de) 1995-09-15 1997-03-20 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
CO4950519A1 (es) 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
WO2000012089A1 (en) 1998-08-31 2000-03-09 Merck & Co., Inc. Novel angiogenesis inhibitors
WO1999045009A1 (en) 1998-03-04 1999-09-10 Bristol-Myers Squibb Company Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
DK2020408T3 (da) 1998-05-29 2013-09-30 Sugen Inc Pyrrol-substitueret 2-indolinon som proteinkinaseinhibitor
UA60365C2 (uk) 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
JP2002520324A (ja) 1998-07-10 2002-07-09 メルク エンド カムパニー インコーポレーテッド 新規な血管形成インヒビター
DE60028740T2 (de) 1999-03-30 2007-05-24 Novartis Ag Phthalazinderivate zur behandlung von entzündlichen erkrankungen
UA72946C2 (uk) 1999-11-05 2005-05-16 Астразенека Аб Похідні хіназоліну як інгібітори васкулярного ендотеліального фактора росту (vegf)
WO2001037820A2 (en) 1999-11-24 2001-05-31 Sugen, Inc. Ionizable indolinone derivatives and their use as ptk ligands
SI1343782T1 (sl) 2000-12-21 2009-10-31 Smithkline Beecham Corp Pirimidinamini kot modulatorji angiogeneze
US7105682B2 (en) 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
US7102009B2 (en) 2001-01-12 2006-09-05 Amgen Inc. Substituted amine derivatives and methods of use
US6878714B2 (en) 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
US6995162B2 (en) * 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US20020147198A1 (en) 2001-01-12 2002-10-10 Guoqing Chen Substituted arylamine derivatives and methods of use
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
US7307088B2 (en) 2002-07-09 2007-12-11 Amgen Inc. Substituted anthranilic amide derivatives and methods of use
TWI329112B (en) 2002-07-19 2010-08-21 Bristol Myers Squibb Co Novel inhibitors of kinases
EP1987023B1 (de) * 2006-02-10 2010-11-24 Amgen, Inc Hydratformen von amg706

Also Published As

Publication number Publication date
JP2009526050A (ja) 2009-07-16
JP2014055143A (ja) 2014-03-27
US7989631B2 (en) 2011-08-02
US20080039501A1 (en) 2008-02-14
AU2007212696A1 (en) 2007-08-16
ES2353482T3 (es) 2011-03-02
EP1987023B1 (de) 2010-11-24
AU2007212696B2 (en) 2011-05-19
CA2641713A1 (en) 2007-08-16
EP1987023A1 (de) 2008-11-05
WO2007092178A1 (en) 2007-08-16
ATE489380T1 (de) 2010-12-15
CA2641713C (en) 2011-11-22

Similar Documents

Publication Publication Date Title
UA101309C2 (ru) Антагонисты активина-actrii и их применение для повышения уровня эритроцитов
DE60038162D1 (de) Celecoxib in festkörperform mit erhöhter bioverfügbarkeit
DE602007010734D1 (de) Hydratformen von amg706
EA200801580A1 (ru) Новые производные пирониндола и способ их получения
ATE322265T1 (de) Pharmazeutische zusammensetzung zur behandlung von kolorektalem krebs welche thalidomid und irinotecan enthält
DE502007002101D1 (de) Arzneimittel mit Dobesilat-Calcium zur Behandlung und Prophylaxe von Sehnenerkrankungen
BRPI0508254A (pt) métodos e composições para o tratamento ou prevenção de distúrbios psiquiátricos com inibidores de cox-2 sozinhos e em combinação com agentes antidepressivos
HK1124546A1 (en) Use of benzo-fused heterocycle sulfamide derivatives for the treatment of mania and bipolar disorder
MX2008012479A (es) Tratamiento de enfermedades neurodegenerativas.
MX2007004248A (es) Derivados heterociclicos de bisarilurea sustituidos como inhibidores de cinasa.
WO2006098603A3 (en) Composition comprising isoorientin for suppressing histamine
ATE454465T1 (de) In-vitro-verfahren zur identifizierung von verbindungen zur krebstherapie
BRPI0908635B8 (pt) composto e/ou um sal farmaceuticamente aceitável do mesmo e composição farmacêutica
SI2903616T1 (en) The use of masitinib in combination with gemcitabine for the treatment of a subgroup of patients suffering from foot-and-mouth disease
EA201270071A1 (ru) Способ лечения пациента, нуждающегося в аспириновой терапии
DE602006021348D1 (de) Feste form von amg 706 und pharmazeutische zusammensetzungen davon
BRPI0511800A (pt) tratamento com irinotecano (cpt-11) e um inibidor de egfr
NZ754328A (en) Marker for acid sphingomyelinase disorders and uses thereof
WO2005081972A3 (en) Maleiimide anti-tumor phosphatase inhibitors
BR112012024522A2 (pt) combinação, uso de uma combinação, composição farmacêutica, forma de dosagem única , kit, e, método para tratar um distúrbio
ATE502637T1 (de) Medikamente zur prävention oder behandlung von herzversagen mit einem anticholinergikum
NO20021437D0 (no) Fremgangsmate til forebyggelse av kolorektal kreft
EA200901145A1 (ru) Применение рибофлавина в лечении гипертензии
ATE496899T1 (de) Tetrahydro- und dihydrochinazolinone
WO2007146375A3 (en) Highly soluble pyrimido-dione-quinoline compounds and their use in the treatment of cancer