DE602006021348D1 - Feste form von amg 706 und pharmazeutische zusammensetzungen davon - Google Patents

Feste form von amg 706 und pharmazeutische zusammensetzungen davon

Info

Publication number
DE602006021348D1
DE602006021348D1 DE602006021348T DE602006021348T DE602006021348D1 DE 602006021348 D1 DE602006021348 D1 DE 602006021348D1 DE 602006021348 T DE602006021348 T DE 602006021348T DE 602006021348 T DE602006021348 T DE 602006021348T DE 602006021348 D1 DE602006021348 D1 DE 602006021348D1
Authority
DE
Germany
Prior art keywords
amg
amorphous
drug substance
crystallization inhibitor
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006021348T
Other languages
English (en)
Inventor
Belle B Liu
Gonzalo Alva
Nina Cauchon
Seshadri Neervannan
Pengzu Zhou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE602006021348D1 publication Critical patent/DE602006021348D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006021348T 2005-12-23 2006-12-08 Feste form von amg 706 und pharmazeutische zusammensetzungen davon Active DE602006021348D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75390905P 2005-12-23 2005-12-23
US11/636,183 US20080108664A1 (en) 2005-12-23 2006-12-07 Solid-state form of AMG 706 and pharmaceutical compositions thereof
PCT/US2006/047238 WO2007087026A2 (en) 2005-12-23 2006-12-08 Solid-state form of amg 706 and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
DE602006021348D1 true DE602006021348D1 (de) 2011-05-26

Family

ID=38198261

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006021348T Active DE602006021348D1 (de) 2005-12-23 2006-12-08 Feste form von amg 706 und pharmazeutische zusammensetzungen davon

Country Status (8)

Country Link
US (3) US20080108664A1 (de)
EP (1) EP2013198B1 (de)
JP (1) JP5830216B2 (de)
AT (1) ATE505464T1 (de)
AU (1) AU2006336563B2 (de)
CA (1) CA2633077C (de)
DE (1) DE602006021348D1 (de)
WO (1) WO2007087026A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102026634B (zh) 2008-04-10 2014-01-22 弗吉尼亚州立邦联大学 诱导肿瘤缺氧以治疗癌症
WO2009140549A1 (en) * 2008-05-14 2009-11-19 Amgen Inc. Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer
US20100003319A1 (en) * 2008-07-02 2010-01-07 Glenmark Generics Ltd. Raloxifene immediate release tablets
WO2011112915A2 (en) * 2010-03-11 2011-09-15 Health Research, Inc. Methods and compositions containing fc fusiong proteins for enhancing immune responses
WO2012068549A2 (en) 2010-11-19 2012-05-24 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
EP2739252A4 (de) 2011-08-05 2015-08-12 Forsight Vision4 Inc Abgabe kleiner moleküle über eine implantierbare therapeutische vorrichtung
WO2014152959A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
KR20170040798A (ko) 2014-08-08 2017-04-13 포사이트 비젼4, 인크. 수용체 티로신 키나제 억제제의 안정한 가용성 제제 및 그의 제조 방법

Family Cites Families (28)

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Publication number Priority date Publication date Assignee Title
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
JP2762522B2 (ja) 1989-03-06 1998-06-04 藤沢薬品工業株式会社 血管新生阻害剤
JPH02279769A (ja) * 1989-04-20 1990-11-15 Kao Corp ブリリアントカーミン６ｂナトリウム塩の無定形物、その製造法及びこれを含有する化粧料
US5112946A (en) 1989-07-06 1992-05-12 Repligen Corporation Modified pf4 compositions and methods of use
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
CA2222811C (en) * 1995-06-01 2008-09-30 G.D. Searle & Co. Stabilized solid dispersions of misoprostol
HRP960312B1 (en) 1995-07-17 2001-10-31 Warner Lambert Co NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS /R-(R*, R*)/-2-(4-FLUOROPHENYL)-"beta", "delta"-DIHYDROXY-5-PHENYL-4-/(PHENYLAMINO)CARBONYL/-1H-PYRROLE -1-HEPTANOIC ACID CALCIUM SALT (2 : 1)
DE19534177A1 (de) 1995-09-15 1997-03-20 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
FR2740686B1 (fr) 1995-11-03 1998-01-16 Sanofi Sa Formulation pharmaceutique lyophilisee stable
US6582921B2 (en) * 1996-07-29 2003-06-24 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses thereof
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
WO1999045009A1 (en) 1998-03-04 1999-09-10 Bristol-Myers Squibb Company Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
NZ508815A (en) 1998-05-29 2005-02-25 Sugen Inc Pyrrole substituted 2-indolinone protein kinase inhibitors
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
AU747427B2 (en) 1998-07-10 2002-05-16 Merck & Co., Inc. Novel angiogenesis inhibitors
AU760020B2 (en) 1998-08-31 2003-05-08 Merck & Co., Inc. Novel angiogenesis inhibitors
WO2000059509A1 (en) 1999-03-30 2000-10-12 Novartis Ag Phthalazine derivatives for treating inflammatory diseases
PT1676845E (pt) 1999-11-05 2008-08-05 Astrazeneca Ab Novos derivados de quinazolina
EP1233943B1 (de) 1999-11-24 2011-06-29 Sugen, Inc. Ionisierbare indolinon derivate und deren verwendung als ptk liganden
KR100847169B1 (ko) 2000-12-21 2008-07-17 글락소 그룹 리미티드 혈관형성 조절제로서의 피리미딘아민
US6878714B2 (en) * 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
US20020147198A1 (en) 2001-01-12 2002-10-10 Guoqing Chen Substituted arylamine derivatives and methods of use
US7102009B2 (en) 2001-01-12 2006-09-05 Amgen Inc. Substituted amine derivatives and methods of use
US7105682B2 (en) 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
US6995162B2 (en) * 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US20030232871A1 (en) 2002-03-15 2003-12-18 Sheikh Ahmad Y. Crystalline parecoxib sodium
US7307088B2 (en) 2002-07-09 2007-12-11 Amgen Inc. Substituted anthranilic amide derivatives and methods of use
TWI329112B (en) 2002-07-19 2010-08-21 Bristol Myers Squibb Co Novel inhibitors of kinases

Also Published As

Publication number Publication date
CA2633077C (en) 2012-02-21
WO2007087026A3 (en) 2007-09-13
US20080108664A1 (en) 2008-05-08
WO2007087026A2 (en) 2007-08-02
JP5830216B2 (ja) 2015-12-09
AU2006336563A1 (en) 2007-08-02
US8648199B2 (en) 2014-02-11
US20130317227A1 (en) 2013-11-28
WO2007087026A9 (en) 2009-01-08
US20100331548A1 (en) 2010-12-30
EP2013198A2 (de) 2009-01-14
CA2633077A1 (en) 2007-08-02
JP2009527460A (ja) 2009-07-30
ATE505464T1 (de) 2011-04-15
EP2013198B1 (de) 2011-04-13
AU2006336563B2 (en) 2010-08-26

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