DE602007009074D1 - Imidazo-verbindungen - Google Patents
Imidazo-verbindungenInfo
- Publication number
- DE602007009074D1 DE602007009074D1 DE602007009074T DE602007009074T DE602007009074D1 DE 602007009074 D1 DE602007009074 D1 DE 602007009074D1 DE 602007009074 T DE602007009074 T DE 602007009074T DE 602007009074 T DE602007009074 T DE 602007009074T DE 602007009074 D1 DE602007009074 D1 DE 602007009074D1
- Authority
- DE
- Germany
- Prior art keywords
- imidazo
- connections
- imidazo connections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH6202006 | 2006-04-12 | ||
PCT/EP2007/053585 WO2007116099A1 (en) | 2006-04-12 | 2007-04-12 | Imidazo compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007009074D1 true DE602007009074D1 (de) | 2010-10-21 |
Family
ID=38462029
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007009074T Active DE602007009074D1 (de) | 2006-04-12 | 2007-04-12 | Imidazo-verbindungen |
DE602007005788T Expired - Fee Related DE602007005788D1 (de) | 2006-04-12 | 2007-04-12 | Imidazo-verbindungen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007005788T Expired - Fee Related DE602007005788D1 (de) | 2006-04-12 | 2007-04-12 | Imidazo-verbindungen |
Country Status (15)
Country | Link |
---|---|
US (3) | US20090192149A1 (de) |
EP (2) | EP2007771B1 (de) |
JP (2) | JP5260496B2 (de) |
CN (2) | CN101421279B (de) |
AR (1) | AR060590A1 (de) |
AT (2) | ATE463498T1 (de) |
BR (2) | BRPI0711540A2 (de) |
CA (2) | CA2649217A1 (de) |
DE (2) | DE602007009074D1 (de) |
ES (2) | ES2352358T3 (de) |
IL (2) | IL194584A0 (de) |
PL (2) | PL2007770T3 (de) |
PT (2) | PT2007771E (de) |
TW (1) | TW200808813A (de) |
WO (2) | WO2007116099A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2568163A1 (en) * | 2004-05-28 | 2005-12-15 | Speedel Experimenta Ag | Bicyclic, nitrogen-containing heterocycles as aromatase inhibitors |
TW200804378A (en) * | 2005-12-09 | 2008-01-16 | Speedel Experimenta Ag | Organic compounds |
TW200808813A (en) * | 2006-04-12 | 2008-02-16 | Speedel Experimenta Ag | Imidazo compounds |
TW200808812A (en) * | 2006-04-12 | 2008-02-16 | Speedel Experimenta Ag | Imidazo compounds |
KR101442897B1 (ko) | 2009-05-28 | 2014-09-23 | 노파르티스 아게 | 네프릴리신 억제제로서의 치환된 아미노프로피온산 유도체 |
CN102448928B (zh) | 2009-05-28 | 2014-10-01 | 诺华股份有限公司 | 作为中性溶酶(neprilysin)抑制剂的取代的氨基丁酸衍生物 |
JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
US8877815B2 (en) | 2010-11-16 | 2014-11-04 | Novartis Ag | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP |
US8673974B2 (en) | 2010-11-16 | 2014-03-18 | Novartis Ag | Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors |
SG10201605304VA (en) | 2011-07-08 | 2016-08-30 | Novartis Ag | Method of treating atherosclerosis in high triglyceride subjects |
UY35144A (es) | 2012-11-20 | 2014-06-30 | Novartis Ag | Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca |
DK2956464T3 (en) | 2013-02-14 | 2018-07-16 | Novartis Ag | Substituted bisphenyl-butane phosphonic acid derivatives as NEP (neutral endopeptidase) inhibitors |
EP3024492A2 (de) | 2013-07-25 | 2016-06-01 | Novartis AG | Biokonjugate von synthetischen apelinpolypeptiden |
PE20160878A1 (es) | 2013-07-25 | 2016-09-08 | Novartis Ag | Polipeptidos ciclicos para el tratamiento de la insuficiencia cardiaca |
LT3172212T (lt) * | 2014-07-24 | 2018-08-27 | Boehringer Ingelheim International Gmbh | Aldosterono sintazės inhibitoriai |
CU20170093A7 (es) | 2015-01-23 | 2017-09-06 | Novartis Ag | Conjugados de ácidos grasos y apelina sintética con mayor vida media |
JOP20190086A1 (ar) | 2016-10-21 | 2019-04-18 | Novartis Ag | مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب |
UY38072A (es) | 2018-02-07 | 2019-10-01 | Novartis Ag | Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos |
JP2022509184A (ja) | 2018-11-27 | 2022-01-20 | ノバルティス アーゲー | 代謝性障害の処置のためのプロタンパク質コンバターゼスブチリシン/ケキシン9型(pcsk9)阻害剤としての環状ペプチド |
UY38485A (es) | 2018-11-27 | 2020-06-30 | Novartis Ag | Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación |
EP3887363A1 (de) | 2018-11-27 | 2021-10-06 | Novartis AG | Zyklische pentamer-verbindungen als proprotein-konvertase-subtilisin-kexin-typ 9 (pcsk9)-inhibitoren zur behandlung von stoffwechselstörung |
EP3962903A1 (de) | 2019-05-01 | 2022-03-09 | Boehringer Ingelheim International GmbH | (r)-(2-methyloxiran-2-yl)methyl 4-bromobenzolsulfonat |
TW202333563A (zh) | 2021-11-12 | 2023-09-01 | 瑞士商諾華公司 | 用於治療疾病或障礙之二胺基環戊基吡啶衍生物 |
AR127698A1 (es) | 2021-11-23 | 2024-02-21 | Novartis Ag | Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0670064B2 (ja) * | 1986-12-08 | 1994-09-07 | 三井石油化学工業株式会社 | 二環性イミダゾ−ル誘導体 |
AU6015796A (en) * | 1995-06-14 | 1997-01-15 | Yamanouchi Pharmaceutical Co., Ltd. | Fused imidazole derivatives and medicinal composition thereof |
JPH0971586A (ja) * | 1995-09-07 | 1997-03-18 | Yamanouchi Pharmaceut Co Ltd | 新規な二環性縮合イミダゾール誘導体 |
CA2405895A1 (en) * | 2000-04-12 | 2001-10-18 | Ronald Edward Steele | Combination of organic compounds |
DE60307483T2 (de) * | 2002-08-07 | 2007-07-05 | Novartis Ag | Organische verbindungen als mittel zur behandlung von aldosteronbedingten zuständen |
CA2568163A1 (en) * | 2004-05-28 | 2005-12-15 | Speedel Experimenta Ag | Bicyclic, nitrogen-containing heterocycles as aromatase inhibitors |
EP2261225A1 (de) * | 2004-05-28 | 2010-12-15 | Novartis AG | Heterocyclische Verbindungen und deren Verwendung als Aldosteronsynthaseinhibitoren |
CA2568164A1 (en) * | 2004-05-28 | 2005-12-15 | Speedel Experimenta Ag | Heterocyclic compounds and their use as aldosterone synthase inhibitors |
TW200611897A (en) * | 2004-07-09 | 2006-04-16 | Speedel Experimenta Ag | Organic compounds |
TW200804378A (en) * | 2005-12-09 | 2008-01-16 | Speedel Experimenta Ag | Organic compounds |
TW200808812A (en) * | 2006-04-12 | 2008-02-16 | Speedel Experimenta Ag | Imidazo compounds |
TW200808813A (en) * | 2006-04-12 | 2008-02-16 | Speedel Experimenta Ag | Imidazo compounds |
-
2007
- 2007-04-10 TW TW096112449A patent/TW200808813A/zh unknown
- 2007-04-11 AR ARP070101536A patent/AR060590A1/es unknown
- 2007-04-12 PL PL07728052T patent/PL2007770T3/pl unknown
- 2007-04-12 BR BRPI0711540-7A patent/BRPI0711540A2/pt not_active IP Right Cessation
- 2007-04-12 WO PCT/EP2007/053585 patent/WO2007116099A1/en active Application Filing
- 2007-04-12 PT PT07728054T patent/PT2007771E/pt unknown
- 2007-04-12 US US12/226,212 patent/US20090192149A1/en not_active Abandoned
- 2007-04-12 PL PL07728054T patent/PL2007771T3/pl unknown
- 2007-04-12 JP JP2009504755A patent/JP5260496B2/ja not_active Expired - Fee Related
- 2007-04-12 CN CN2007800132920A patent/CN101421279B/zh not_active Expired - Fee Related
- 2007-04-12 CA CA002649217A patent/CA2649217A1/en not_active Abandoned
- 2007-04-12 DE DE602007009074T patent/DE602007009074D1/de active Active
- 2007-04-12 CA CA002649213A patent/CA2649213A1/en not_active Abandoned
- 2007-04-12 CN CNA2007800129595A patent/CN101421277A/zh active Pending
- 2007-04-12 DE DE602007005788T patent/DE602007005788D1/de not_active Expired - Fee Related
- 2007-04-12 BR BRPI0710614-9A patent/BRPI0710614A2/pt not_active IP Right Cessation
- 2007-04-12 WO PCT/EP2007/053587 patent/WO2007116101A1/en active Application Filing
- 2007-04-12 EP EP07728054A patent/EP2007771B1/de active Active
- 2007-04-12 AT AT07728054T patent/ATE463498T1/de active
- 2007-04-12 EP EP07728052A patent/EP2007770B1/de not_active Not-in-force
- 2007-04-12 JP JP2009504757A patent/JP2009534319A/ja active Pending
- 2007-04-12 ES ES07728052T patent/ES2352358T3/es active Active
- 2007-04-12 US US12/226,214 patent/US7879847B2/en not_active Expired - Fee Related
- 2007-04-12 ES ES07728054T patent/ES2342689T3/es active Active
- 2007-04-12 AT AT07728052T patent/ATE480545T1/de active
- 2007-04-12 PT PT07728052T patent/PT2007770E/pt unknown
-
2008
- 2008-10-06 IL IL194584A patent/IL194584A0/en unknown
- 2008-10-06 IL IL194583A patent/IL194583A0/en unknown
-
2010
- 2010-12-22 US US12/975,949 patent/US8138176B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |