DE602006017675D1 - Herstellung von 2-substituierten 4-chlor-5-formylimidazolen durch vilsmeier-reaktion des kondensationsprodukts von glycin und einem imidoester mit einem formamid in gegenwart eines triflat- (trifluormethansulfonat-) katalysators - Google Patents
Herstellung von 2-substituierten 4-chlor-5-formylimidazolen durch vilsmeier-reaktion des kondensationsprodukts von glycin und einem imidoester mit einem formamid in gegenwart eines triflat- (trifluormethansulfonat-) katalysatorsInfo
- Publication number
- DE602006017675D1 DE602006017675D1 DE602006017675T DE602006017675T DE602006017675D1 DE 602006017675 D1 DE602006017675 D1 DE 602006017675D1 DE 602006017675 T DE602006017675 T DE 602006017675T DE 602006017675 T DE602006017675 T DE 602006017675T DE 602006017675 D1 DE602006017675 D1 DE 602006017675D1
- Authority
- DE
- Germany
- Prior art keywords
- substituted
- chloro
- catalyst
- formylimidazolenes
- triflated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67147105P | 2005-04-15 | 2005-04-15 | |
| EP05103014 | 2005-04-15 | ||
| PCT/NL2006/050077 WO2006110037A2 (en) | 2005-04-15 | 2006-04-07 | Preparation of 2-substituted 4-chl0r0-5-f0rmylimidaz0les by vilsmeier reaction of the condensation product of glycine and an imido ester with a formamide in the presence of a triflate (trifluormethanξsulphonate) catalyst |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006017675D1 true DE602006017675D1 (de) | 2010-12-02 |
Family
ID=34939316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006017675T Active DE602006017675D1 (de) | 2005-04-15 | 2006-04-07 | Herstellung von 2-substituierten 4-chlor-5-formylimidazolen durch vilsmeier-reaktion des kondensationsprodukts von glycin und einem imidoester mit einem formamid in gegenwart eines triflat- (trifluormethansulfonat-) katalysators |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080200690A1 (de) |
| EP (1) | EP1871745B1 (de) |
| JP (1) | JP2008535911A (de) |
| AT (1) | ATE485278T1 (de) |
| DE (1) | DE602006017675D1 (de) |
| WO (1) | WO2006110037A2 (de) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54148788A (en) * | 1978-05-15 | 1979-11-21 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation |
| JPS5671074A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
| RU2103262C1 (ru) * | 1992-07-16 | 1998-01-27 | Лонца АГ Гампель/Валлис | Способ получения 2-замещенных 5-хлоримидазол-4-карбальдегидов |
| US5336779A (en) * | 1992-10-08 | 1994-08-09 | Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha | Method of producing formylimidazoles |
| US5442075A (en) * | 1993-03-12 | 1995-08-15 | Lonza Ltd. | Process for the production of 2-substituted 5-chlorimidazole-4-carbaldehydes |
| US5484939A (en) * | 1993-03-12 | 1996-01-16 | Lonza Ltd. | 2-substituted 5-chlorimidazoles |
| CA2135541C (en) * | 1993-11-15 | 2006-01-10 | Gareth Griffiths | Process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes |
| JP4103149B2 (ja) | 1996-01-05 | 2008-06-18 | ロンザ リミテッド | ２−置換５−クロロイミダゾール−４−カルブアルデヒドの製造方法 |
| KR100567183B1 (ko) | 1997-11-14 | 2006-06-13 | 론자 아게 | 포르밀이미다졸의제조방법 |
-
2006
- 2006-04-07 EP EP06733056A patent/EP1871745B1/de active Active
- 2006-04-07 AT AT06733056T patent/ATE485278T1/de not_active IP Right Cessation
- 2006-04-07 JP JP2008506390A patent/JP2008535911A/ja not_active Withdrawn
- 2006-04-07 WO PCT/NL2006/050077 patent/WO2006110037A2/en active Application Filing
- 2006-04-07 DE DE602006017675T patent/DE602006017675D1/de active Active
- 2006-04-07 US US11/911,659 patent/US20080200690A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008535911A (ja) | 2008-09-04 |
| EP1871745A2 (de) | 2008-01-02 |
| EP1871745B1 (de) | 2010-10-20 |
| WO2006110037A3 (en) | 2007-04-05 |
| WO2006110037A2 (en) | 2006-10-19 |
| ATE485278T1 (de) | 2010-11-15 |
| US20080200690A1 (en) | 2008-08-21 |
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