DE602006016593D1 - Herstellung von famciclovir und anderen purinderivaten - Google Patents

Herstellung von famciclovir und anderen purinderivaten

Info

Publication number
DE602006016593D1
DE602006016593D1 DE602006016593T DE602006016593T DE602006016593D1 DE 602006016593 D1 DE602006016593 D1 DE 602006016593D1 DE 602006016593 T DE602006016593 T DE 602006016593T DE 602006016593 T DE602006016593 T DE 602006016593T DE 602006016593 D1 DE602006016593 D1 DE 602006016593D1
Authority
DE
Germany
Prior art keywords
purine derivatives
famciclovir
preparation
purine
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006016593T
Other languages
German (de)
English (en)
Inventor
Liang He
Weiping Jiang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chongqing Shenghuaxi Pharmaceutical Co Ltd
Arrow International Ltd
Original Assignee
Chongqing Shenghuaxi Pharmaceutical Co Ltd
Arrow International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chongqing Shenghuaxi Pharmaceutical Co Ltd, Arrow International Ltd filed Critical Chongqing Shenghuaxi Pharmaceutical Co Ltd
Publication of DE602006016593D1 publication Critical patent/DE602006016593D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602006016593T 2005-05-20 2006-05-19 Herstellung von famciclovir und anderen purinderivaten Active DE602006016593D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0510345A GB2426247A (en) 2005-05-20 2005-05-20 Methods of preparing purine derivatives such as famciclovir
PCT/GB2006/001877 WO2006123175A1 (en) 2005-05-20 2006-05-19 Preparation of famciclovir and other purine derivatives

Publications (1)

Publication Number Publication Date
DE602006016593D1 true DE602006016593D1 (de) 2010-10-14

Family

ID=34834391

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006016593T Active DE602006016593D1 (de) 2005-05-20 2006-05-19 Herstellung von famciclovir und anderen purinderivaten

Country Status (17)

Country Link
US (1) US7601835B2 (enExample)
EP (1) EP1883639B1 (enExample)
JP (1) JP5227166B2 (enExample)
CN (1) CN101233134B (enExample)
AT (1) ATE479688T1 (enExample)
AU (1) AU2006248745B2 (enExample)
BR (1) BRPI0609632A2 (enExample)
CA (1) CA2608490C (enExample)
DE (1) DE602006016593D1 (enExample)
DK (1) DK1883639T3 (enExample)
ES (1) ES2351925T3 (enExample)
GB (1) GB2426247A (enExample)
NZ (1) NZ563636A (enExample)
PL (1) PL1883639T3 (enExample)
PT (1) PT1883639E (enExample)
TW (1) TW200716638A (enExample)
WO (1) WO2006123175A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2496684A1 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd Crystalline solid famciclovir forms i, ii, iii and preparation thereof
WO2004099208A1 (en) * 2003-04-30 2004-11-18 Teva Pharmaceutical Industries Ltd. Process for the preparation of famciclovir
TW200613304A (en) * 2004-05-18 2006-05-01 Teva Pharma Drying process for preparing crystalline solid famciclovir
WO2008072074A1 (en) * 2006-12-11 2008-06-19 Aurobindo Pharma Limited An improved process for the preparation of purine derivative
CN101555249B (zh) * 2008-04-08 2011-05-11 浙江海正药业股份有限公司 泛昔洛韦的合成方法
CN102924455A (zh) * 2011-08-11 2013-02-13 重庆圣华曦药业股份有限公司 一种泛昔洛韦中间体的合成方法
CN104496991A (zh) * 2014-11-04 2015-04-08 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法
CN104744472A (zh) * 2015-03-12 2015-07-01 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法
CN109456329B (zh) * 2018-11-19 2021-03-09 迪嘉药业集团有限公司 一种泛昔洛韦的制备方法
ES3037292T3 (en) 2019-12-11 2025-09-30 Taro Pharma Ind Preparation of trifarotene and intermediates and polymorphs thereof
CN112979653A (zh) * 2019-12-12 2021-06-18 上药康丽（常州）药业有限公司 一种利用微通道反应器合成泛昔洛韦的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
SE8406538D0 (sv) 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
GB9402161D0 (en) 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
GB9407698D0 (en) 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
JPH11180983A (ja) 1997-12-24 1999-07-06 Sumika Fine Chemicals Co Ltd ９置換２−アミノ−６−ハロゲノプリンおよびその製法
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807114D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
SI20022A (sl) * 1998-07-29 2000-02-29 Kemijski inštitut Alkilno substituirani purinovi derivati in njihova priprava
DE60202245T2 (de) 2001-08-30 2005-09-01 Ajinomoto Co., Inc. Herstellungsmethode von Famciclovir und Herstellungs- bzw. Kristallisationsmethode eines entsprechenden Intermediates
JP2003146988A (ja) * 2001-08-30 2003-05-21 Ajinomoto Co Inc ファムシクロビルの製造方法、並びにその中間体の製造および晶析方法
KR100573860B1 (ko) 2003-06-13 2006-04-25 경동제약 주식회사 2-아미노-9-(2-치환에틸)푸린을 이용한 9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의 제조방법
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines

Also Published As

Publication number Publication date
JP2008540628A (ja) 2008-11-20
CA2608490C (en) 2013-09-10
US20060264629A1 (en) 2006-11-23
GB0510345D0 (en) 2005-06-29
TW200716638A (en) 2007-05-01
US7601835B2 (en) 2009-10-13
CN101233134B (zh) 2013-01-23
GB2426247A (en) 2006-11-22
AU2006248745A1 (en) 2006-11-23
PT1883639E (pt) 2010-12-07
ES2351925T3 (es) 2011-02-14
CN101233134A (zh) 2008-07-30
AU2006248745B2 (en) 2011-06-23
BRPI0609632A2 (pt) 2011-10-18
JP5227166B2 (ja) 2013-07-03
EP1883639A1 (en) 2008-02-06
DK1883639T3 (da) 2010-11-15
ATE479688T1 (de) 2010-09-15
PL1883639T3 (pl) 2011-04-29
EP1883639B1 (en) 2010-09-01
CA2608490A1 (en) 2006-11-23
NZ563636A (en) 2010-10-29
WO2006123175A1 (en) 2006-11-23

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