DE602006008349D1 - Quaternäre 3-amido, n-methylpyridiniumsalze als entzündungshemmende mittel - Google Patents
Quaternäre 3-amido, n-methylpyridiniumsalze als entzündungshemmende mittelInfo
- Publication number
- DE602006008349D1 DE602006008349D1 DE602006008349T DE602006008349T DE602006008349D1 DE 602006008349 D1 DE602006008349 D1 DE 602006008349D1 DE 602006008349 T DE602006008349 T DE 602006008349T DE 602006008349 T DE602006008349 T DE 602006008349T DE 602006008349 D1 DE602006008349 D1 DE 602006008349D1
- Authority
- DE
- Germany
- Prior art keywords
- inflammatory
- compounds
- amido
- quaternary
- anion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- PQBAWAQIRZIWIV-UHFFFAOYSA-N N-methylpyridinium Chemical class C[N+]1=CC=CC=C1 PQBAWAQIRZIWIV-UHFFFAOYSA-N 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000001450 anions Chemical class 0.000 abstract 2
- 150000001768 cations Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- LDHMAVIPBRSVRG-UHFFFAOYSA-O 1-methylnicotinamide Chemical compound C[N+]1=CC=CC(C(N)=O)=C1 LDHMAVIPBRSVRG-UHFFFAOYSA-O 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH19542005 | 2005-12-09 | ||
| PCT/CH2006/000672 WO2007065281A1 (en) | 2005-12-09 | 2006-11-29 | Quaternary 3 -amido, n-methylpyridinium salts as anti -inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006008349D1 true DE602006008349D1 (de) | 2009-09-17 |
Family
ID=37913716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006008349T Expired - Fee Related DE602006008349D1 (de) | 2005-12-09 | 2006-11-29 | Quaternäre 3-amido, n-methylpyridiniumsalze als entzündungshemmende mittel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080249140A1 (de) |
| EP (1) | EP1963270B1 (de) |
| AT (1) | ATE438625T1 (de) |
| CA (1) | CA2629913A1 (de) |
| DE (1) | DE602006008349D1 (de) |
| MX (1) | MX2008007259A (de) |
| WO (1) | WO2007065281A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106604717B (zh) * | 2014-09-10 | 2020-09-11 | Gsk消费者健康有限公司 | 局部用双氯芬酸钠组合物 |
| ES2967074T3 (es) * | 2016-07-18 | 2024-04-25 | Pharmena S A | 1 metilnicotinamida para el tratamiento de una enfermedad cardiovascular |
| AU2018231842B2 (en) | 2017-03-07 | 2024-03-21 | LYOTROPIC DELIVERY SYSTEMS Ltd | Topical delivery systems for active compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3340028A1 (de) * | 1983-11-03 | 1985-05-15 | Josef Dipl.-Chem. Dr.Rer.Nat. Klosa | Neues salicylsaeuresalz |
| PL190755B1 (pl) * | 1999-01-07 | 2006-01-31 | Pharmena Sp Z Oo | Preparat do leczenia i profilaktyki chorób skóry |
| PL364348A1 (en) * | 2004-01-12 | 2005-07-25 | PHARMENA Sp.z o.o. | Application of quaternary pyridine salts as vessel protection agent |
-
2006
- 2006-11-29 MX MX2008007259A patent/MX2008007259A/es not_active Application Discontinuation
- 2006-11-29 WO PCT/CH2006/000672 patent/WO2007065281A1/en active Application Filing
- 2006-11-29 DE DE602006008349T patent/DE602006008349D1/de not_active Expired - Fee Related
- 2006-11-29 AT AT06804891T patent/ATE438625T1/de not_active IP Right Cessation
- 2006-11-29 EP EP06804891A patent/EP1963270B1/de not_active Not-in-force
- 2006-11-29 US US12/094,169 patent/US20080249140A1/en not_active Abandoned
- 2006-11-29 CA CA002629913A patent/CA2629913A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2008007259A (es) | 2008-09-23 |
| WO2007065281A1 (en) | 2007-06-14 |
| US20080249140A1 (en) | 2008-10-09 |
| CA2629913A1 (en) | 2007-06-14 |
| ATE438625T1 (de) | 2009-08-15 |
| EP1963270A1 (de) | 2008-09-03 |
| EP1963270B1 (de) | 2009-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |