ATE438625T1 - Quaternäre 3-amido, n-methylpyridiniumsalze als entzündungshemmende mittel - Google Patents
Quaternäre 3-amido, n-methylpyridiniumsalze als entzündungshemmende mittelInfo
- Publication number
- ATE438625T1 ATE438625T1 AT06804891T AT06804891T ATE438625T1 AT E438625 T1 ATE438625 T1 AT E438625T1 AT 06804891 T AT06804891 T AT 06804891T AT 06804891 T AT06804891 T AT 06804891T AT E438625 T1 ATE438625 T1 AT E438625T1
- Authority
- AT
- Austria
- Prior art keywords
- inflammatory
- compounds
- amido
- quaternary
- anion
- Prior art date
Links
- PQBAWAQIRZIWIV-UHFFFAOYSA-N N-methylpyridinium Chemical class C[N+]1=CC=CC=C1 PQBAWAQIRZIWIV-UHFFFAOYSA-N 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000001450 anions Chemical class 0.000 abstract 2
- 150000001768 cations Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- LDHMAVIPBRSVRG-UHFFFAOYSA-O 1-methylnicotinamide Chemical compound C[N+]1=CC=CC(C(N)=O)=C1 LDHMAVIPBRSVRG-UHFFFAOYSA-O 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH19542005 | 2005-12-09 | ||
| PCT/CH2006/000672 WO2007065281A1 (en) | 2005-12-09 | 2006-11-29 | Quaternary 3 -amido, n-methylpyridinium salts as anti -inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE438625T1 true ATE438625T1 (de) | 2009-08-15 |
Family
ID=37913716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06804891T ATE438625T1 (de) | 2005-12-09 | 2006-11-29 | Quaternäre 3-amido, n-methylpyridiniumsalze als entzündungshemmende mittel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080249140A1 (de) |
| EP (1) | EP1963270B1 (de) |
| AT (1) | ATE438625T1 (de) |
| CA (1) | CA2629913A1 (de) |
| DE (1) | DE602006008349D1 (de) |
| MX (1) | MX2008007259A (de) |
| WO (1) | WO2007065281A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3191082A1 (de) * | 2014-09-10 | 2017-07-19 | Novartis Consumer Health S.A. | Topische diclofenac-natrium-zusammensetzungen |
| US20190282560A1 (en) * | 2016-07-18 | 2019-09-19 | Pharmena S.A. | 1-Methylnicotinamide for the Treatment of Diseases Associated With C-Reactive Protein |
| EP3592336A1 (de) | 2017-03-07 | 2020-01-15 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Topische verabreichungssysteme für wirkstoffe |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3340028A1 (de) * | 1983-11-03 | 1985-05-15 | Josef Dipl.-Chem. Dr.Rer.Nat. Klosa | Neues salicylsaeuresalz |
| PL190755B1 (pl) * | 1999-01-07 | 2006-01-31 | Pharmena Sp Z Oo | Preparat do leczenia i profilaktyki chorób skóry |
| PL364348A1 (en) * | 2004-01-12 | 2005-07-25 | PHARMENA Sp.z o.o. | Application of quaternary pyridine salts as vessel protection agent |
-
2006
- 2006-11-29 DE DE602006008349T patent/DE602006008349D1/de not_active Expired - Fee Related
- 2006-11-29 AT AT06804891T patent/ATE438625T1/de not_active IP Right Cessation
- 2006-11-29 EP EP06804891A patent/EP1963270B1/de not_active Not-in-force
- 2006-11-29 US US12/094,169 patent/US20080249140A1/en not_active Abandoned
- 2006-11-29 CA CA002629913A patent/CA2629913A1/en not_active Abandoned
- 2006-11-29 WO PCT/CH2006/000672 patent/WO2007065281A1/en active Application Filing
- 2006-11-29 MX MX2008007259A patent/MX2008007259A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1963270A1 (de) | 2008-09-03 |
| US20080249140A1 (en) | 2008-10-09 |
| DE602006008349D1 (de) | 2009-09-17 |
| MX2008007259A (es) | 2008-09-23 |
| CA2629913A1 (en) | 2007-06-14 |
| EP1963270B1 (de) | 2009-08-05 |
| WO2007065281A1 (en) | 2007-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |