DE602005026072D1 - Ligand für den formylpeptidrezeptorähnlichen-2 (FPRL2) G Protein gekoppelten Rezeptor - Google Patents
Ligand für den formylpeptidrezeptorähnlichen-2 (FPRL2) G Protein gekoppelten RezeptorInfo
- Publication number
- DE602005026072D1 DE602005026072D1 DE602005026072T DE602005026072T DE602005026072D1 DE 602005026072 D1 DE602005026072 D1 DE 602005026072D1 DE 602005026072 T DE602005026072 T DE 602005026072T DE 602005026072 T DE602005026072 T DE 602005026072T DE 602005026072 D1 DE602005026072 D1 DE 602005026072D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- protein
- fprl2
- ligand
- formyl peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04447122 | 2004-05-14 | ||
EP04447231 | 2004-10-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005026072D1 true DE602005026072D1 (de) | 2011-03-03 |
Family
ID=34982585
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005026072T Active DE602005026072D1 (de) | 2004-05-14 | 2005-05-13 | Ligand für den formylpeptidrezeptorähnlichen-2 (FPRL2) G Protein gekoppelten Rezeptor |
DE602005019495T Active DE602005019495D1 (de) | 2004-05-14 | 2005-05-13 | Ligand für den Formylpeptidrezeptorähnlichen- 2 (FPRL2) G Protein gekoppelten Rezeptor und dessen Anwendung |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005019495T Active DE602005019495D1 (de) | 2004-05-14 | 2005-05-13 | Ligand für den Formylpeptidrezeptorähnlichen- 2 (FPRL2) G Protein gekoppelten Rezeptor und dessen Anwendung |
Country Status (7)
Country | Link |
---|---|
US (3) | US7582416B2 (de) |
EP (2) | EP2020604B1 (de) |
JP (2) | JP4694887B2 (de) |
AT (2) | ATE459004T1 (de) |
CA (2) | CA2504920C (de) |
DE (2) | DE602005026072D1 (de) |
DK (2) | DK2020604T3 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495662B1 (en) * | 1998-10-22 | 2002-12-17 | The General Hospital Corporation | Bioactive peptides and peptide derivatives of parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP) |
WO2001023521A2 (en) * | 1999-09-29 | 2001-04-05 | The General Hospital Corporation | Polypeptide derivatives of parathyroid hormone (pth) |
US7572765B2 (en) * | 2001-07-23 | 2009-08-11 | The General Hospital Corporation | Conformationally constrained parathyroid hormone (PTH) analogs |
AU2003220380A1 (en) * | 2003-03-19 | 2004-11-19 | Bristol-Myers Squibb Company | CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH Alpha-HELIX STABILIZERS |
EP1653985A4 (de) | 2003-07-17 | 2009-08-05 | Gen Hospital Corp | Zwangsform-parathormon (pth)-analoga |
CA2504920C (en) * | 2004-05-14 | 2014-04-01 | Euroscreen S.A. | Ligand for g-protein coupled receptor fprl2 and uses thereof |
US8143374B2 (en) * | 2006-08-04 | 2012-03-27 | The General Hospital Corporation | Polypeptide derivatives of parathyroid hormone (PTH) |
US20090004755A1 (en) * | 2007-03-23 | 2009-01-01 | Biosite, Incorporated | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes |
US8221995B2 (en) | 2007-03-23 | 2012-07-17 | Seok-Won Lee | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes |
PE20090321A1 (es) | 2007-06-04 | 2009-04-20 | Genentech Inc | Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica |
WO2008156858A2 (en) * | 2007-06-20 | 2008-12-24 | University Of Utah Research Foundation | Use of pre-mrna splicing in platelet cells for the diagnosis of disease |
AU2008282805B2 (en) * | 2007-08-01 | 2014-05-01 | Chugai Pharmaceutical Co., Ltd. | Screening methods using G-protein coupled receptors and related compositions |
WO2010063652A1 (en) * | 2008-12-04 | 2010-06-10 | Sanofi-Aventis | Methods and uses involving heme binding protein 1 |
US8563714B2 (en) | 2009-05-18 | 2013-10-22 | Actelion Pharmaceuticals Ltd. | Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists |
WO2011073918A2 (en) | 2009-12-16 | 2011-06-23 | Actelion Pharmaceuticals Ltd | Peptides as modulators of fprl1 and/or fprl2 |
CN103002906B (zh) | 2010-05-13 | 2017-12-29 | 总医院有限公司 | 甲状旁腺激素类似物及其应用 |
JP6782716B2 (ja) * | 2015-06-25 | 2020-11-11 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 抗体またはリガンドの結合および機能を明らかにするための細胞ベースアッセイ法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990005745A1 (en) | 1988-11-18 | 1990-05-31 | The General Hospital Corporation | A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN |
DE69229477T2 (de) | 1991-09-23 | 1999-12-09 | Cambridge Antibody Tech | Methoden zur Herstellung humanisierter Antikörper |
CA2115811A1 (en) | 1993-02-17 | 1994-08-18 | Claus Krebber | A method for in vivo selection of ligand-binding proteins |
ATE219517T1 (de) | 1995-08-18 | 2002-07-15 | Morphosys Ag | Protein-/(poly)peptidbibliotheken |
US7119190B2 (en) * | 1997-04-14 | 2006-10-10 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human G protein-coupled receptors |
ES2192060T5 (es) | 1998-07-06 | 2009-05-01 | Perkinelmer Cellular Sciences Belgium Bvba | Ensayo de bioluminiscencia para agonistas o antagonistas de un receptor acoplado al calcio. |
AU7494200A (en) * | 1999-09-15 | 2001-04-17 | Incyte Genomics, Inc. | Proteins associated with cell differentiation |
US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
JP4184875B2 (ja) * | 2002-06-14 | 2008-11-19 | 武田薬品工業株式会社 | 新規スクリーニング方法 |
CA2504920C (en) * | 2004-05-14 | 2014-04-01 | Euroscreen S.A. | Ligand for g-protein coupled receptor fprl2 and uses thereof |
-
2005
- 2005-05-04 CA CA2504920A patent/CA2504920C/en active Active
- 2005-05-04 CA CA2810292A patent/CA2810292C/en active Active
- 2005-05-13 DE DE602005026072T patent/DE602005026072D1/de active Active
- 2005-05-13 JP JP2005140651A patent/JP4694887B2/ja active Active
- 2005-05-13 DK DK08159325.3T patent/DK2020604T3/da active
- 2005-05-13 AT AT05010407T patent/ATE459004T1/de not_active IP Right Cessation
- 2005-05-13 EP EP08159325A patent/EP2020604B1/de active Active
- 2005-05-13 US US11/129,107 patent/US7582416B2/en active Active
- 2005-05-13 DE DE602005019495T patent/DE602005019495D1/de active Active
- 2005-05-13 DK DK05010407.4T patent/DK1607745T3/da active
- 2005-05-13 EP EP05010407A patent/EP1607745B1/de active Active
- 2005-05-13 AT AT08159325T patent/ATE496304T1/de active
-
2008
- 2008-03-13 US US12/075,849 patent/US7659251B2/en active Active
- 2008-03-13 US US12/075,971 patent/US7842795B2/en active Active
-
2011
- 2011-01-27 JP JP2011015046A patent/JP5314061B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
EP2020604B1 (de) | 2011-01-19 |
EP1607745B1 (de) | 2010-02-24 |
EP2020604A1 (de) | 2009-02-04 |
US20100009406A1 (en) | 2010-01-14 |
EP1607745A2 (de) | 2005-12-21 |
US20090053739A1 (en) | 2009-02-26 |
US20060078559A1 (en) | 2006-04-13 |
JP2006025787A (ja) | 2006-02-02 |
US7659251B2 (en) | 2010-02-09 |
ATE459004T1 (de) | 2010-03-15 |
CA2504920A1 (en) | 2005-11-14 |
CA2504920C (en) | 2014-04-01 |
DE602005019495D1 (de) | 2010-04-08 |
JP4694887B2 (ja) | 2011-06-08 |
JP2011078437A (ja) | 2011-04-21 |
CA2810292C (en) | 2015-09-29 |
DK2020604T3 (da) | 2011-05-16 |
EP1607745A3 (de) | 2006-07-26 |
US7842795B2 (en) | 2010-11-30 |
DK1607745T3 (da) | 2010-06-14 |
US7582416B2 (en) | 2009-09-01 |
JP5314061B2 (ja) | 2013-10-16 |
CA2810292A1 (en) | 2005-11-14 |
ATE496304T1 (de) | 2011-02-15 |
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