DE602005023655D1 - Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion - Google Patents

Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion

Info

Publication number
DE602005023655D1
DE602005023655D1 DE602005023655T DE602005023655T DE602005023655D1 DE 602005023655 D1 DE602005023655 D1 DE 602005023655D1 DE 602005023655 T DE602005023655 T DE 602005023655T DE 602005023655 T DE602005023655 T DE 602005023655T DE 602005023655 D1 DE602005023655 D1 DE 602005023655D1
Authority
DE
Germany
Prior art keywords
days
prednisone
mortality
beclomethasondipropionate
reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005023655T
Other languages
German (de)
English (en)
Inventor
George B Mcdonald
Nicholas Stergis
Steve Kanzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Soligenix Inc
Original Assignee
Soligenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Soligenix Inc filed Critical Soligenix Inc
Publication of DE602005023655D1 publication Critical patent/DE602005023655D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602005023655T 2004-12-30 2005-12-30 Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion Expired - Lifetime DE602005023655D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64017804P 2004-12-30 2004-12-30
PCT/US2005/047666 WO2006072093A2 (en) 2004-12-30 2005-12-30 Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone

Publications (1)

Publication Number Publication Date
DE602005023655D1 true DE602005023655D1 (de) 2010-10-28

Family

ID=36615583

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005023655T Expired - Lifetime DE602005023655D1 (de) 2004-12-30 2005-12-30 Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion

Country Status (13)

Country Link
US (1) US20060252735A1 (enExample)
EP (1) EP1830857B1 (enExample)
JP (1) JP2008526773A (enExample)
KR (1) KR20070089701A (enExample)
CN (2) CN102218070A (enExample)
AT (1) ATE481102T1 (enExample)
AU (1) AU2005321826B2 (enExample)
CA (1) CA2583244A1 (enExample)
DE (1) DE602005023655D1 (enExample)
DK (1) DK1830857T3 (enExample)
IL (1) IL182462A0 (enExample)
NZ (1) NZ554326A (enExample)
WO (1) WO2006072093A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143328A1 (en) * 2001-08-13 2009-06-04 Mcdonald George Method of Treating Cancer by Administration of Topical Active Corticosteroids
NZ593694A (en) * 2008-12-08 2013-09-27 Soligenix Inc Topically active steroids for use in radiation and chemotherapeutics injury
US20170209447A1 (en) * 2014-08-07 2017-07-27 Nitor Therapeutics Use of PNP Inhibitor to Treat Relapse of Malignancy after Hematopoietic Stem Cell Transplant
CN106236736A (zh) * 2016-09-26 2016-12-21 安徽省逸欣铭医药科技有限公司 二丙酸倍氯米松肠溶缓释片及其制备方法
KR20220123004A (ko) * 2019-12-09 2022-09-05 신닥스 파마슈티컬스, 인크. 만성 이식편 대 숙주 질환의 치료를 위한 항체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096728A (en) * 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
US5747474A (en) * 1996-07-29 1998-05-05 Immune Modulation, Inc. Immunosuppression by administration of N6,N6 -disubstituted cAMP's, analogues thereof, and related nucleosides
US6096731A (en) * 1998-06-24 2000-08-01 Institute For Drug Research, Inc. Method for preventing tissue damage associated with graft-versus-host or host-versus-graft disease following transplantation
US20020086857A1 (en) * 2000-09-15 2002-07-04 Mcdonald George B. Method of long-term treatment of graft-versus-host disease using topical active corticosterioids
NZ528607A (en) * 2001-03-15 2007-11-30 Enteron Pharmaceuticals Inc Method of treating inflammatory GI disorders using topically active corticosteroids to reduce symptoms without causing the side effects associated with systemic steroid administration
US20030032631A1 (en) * 2001-08-13 2003-02-13 Mcdonald George B. Method of treatment of cancer by controlling graft-versus-leukemia using topical active corticosteriods
JP4014912B2 (ja) * 2001-09-28 2007-11-28 株式会社ルネサステクノロジ 半導体装置

Also Published As

Publication number Publication date
NZ554326A (en) 2010-10-29
DK1830857T3 (da) 2011-02-07
KR20070089701A (ko) 2007-08-31
WO2006072093A2 (en) 2006-07-06
WO2006072093A3 (en) 2007-03-22
EP1830857B1 (en) 2010-09-15
EP1830857A2 (en) 2007-09-12
US20060252735A1 (en) 2006-11-09
CN102218070A (zh) 2011-10-19
CA2583244A1 (en) 2006-07-06
AU2005321826A1 (en) 2006-07-06
CN101060848B (zh) 2011-06-22
CN101060848A (zh) 2007-10-24
IL182462A0 (en) 2008-04-13
ATE481102T1 (de) 2010-10-15
EP1830857A4 (en) 2008-02-27
JP2008526773A (ja) 2008-07-24
AU2005321826B2 (en) 2012-03-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SOLIGENIX, INC., PRINCETON, N.J., US