ATE481102T1 - Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion - Google Patents

Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion

Info

Publication number
ATE481102T1
ATE481102T1 AT05856121T AT05856121T ATE481102T1 AT E481102 T1 ATE481102 T1 AT E481102T1 AT 05856121 T AT05856121 T AT 05856121T AT 05856121 T AT05856121 T AT 05856121T AT E481102 T1 ATE481102 T1 AT E481102T1
Authority
AT
Austria
Prior art keywords
days
prednisone
mortality associated
versus host
graft versus
Prior art date
Application number
AT05856121T
Other languages
German (de)
English (en)
Inventor
George B Mcdonald
Nicholas Stergis
Steve Kanzer
Original Assignee
Soligenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Soligenix Inc filed Critical Soligenix Inc
Application granted granted Critical
Publication of ATE481102T1 publication Critical patent/ATE481102T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05856121T 2004-12-30 2005-12-30 Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion ATE481102T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64017804P 2004-12-30 2004-12-30
PCT/US2005/047666 WO2006072093A2 (en) 2004-12-30 2005-12-30 Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone

Publications (1)

Publication Number Publication Date
ATE481102T1 true ATE481102T1 (de) 2010-10-15

Family

ID=36615583

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05856121T ATE481102T1 (de) 2004-12-30 2005-12-30 Beclomethasondipropionat und prednison zur verminderung der sterblichkeit in zusammenhang mit der graft-versus-host-reaktion

Country Status (13)

Country Link
US (1) US20060252735A1 (enExample)
EP (1) EP1830857B1 (enExample)
JP (1) JP2008526773A (enExample)
KR (1) KR20070089701A (enExample)
CN (2) CN102218070A (enExample)
AT (1) ATE481102T1 (enExample)
AU (1) AU2005321826B2 (enExample)
CA (1) CA2583244A1 (enExample)
DE (1) DE602005023655D1 (enExample)
DK (1) DK1830857T3 (enExample)
IL (1) IL182462A0 (enExample)
NZ (1) NZ554326A (enExample)
WO (1) WO2006072093A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143328A1 (en) * 2001-08-13 2009-06-04 Mcdonald George Method of Treating Cancer by Administration of Topical Active Corticosteroids
AU2009333538B2 (en) * 2008-12-08 2014-09-11 Soligenix, Inc. Topically active steroids for use in radiation and chemotherapeutics injury
US20170209447A1 (en) * 2014-08-07 2017-07-27 Nitor Therapeutics Use of PNP Inhibitor to Treat Relapse of Malignancy after Hematopoietic Stem Cell Transplant
CN106236736A (zh) * 2016-09-26 2016-12-21 安徽省逸欣铭医药科技有限公司 二丙酸倍氯米松肠溶缓释片及其制备方法
KR20220123004A (ko) * 2019-12-09 2022-09-05 신닥스 파마슈티컬스, 인크. 만성 이식편 대 숙주 질환의 치료를 위한 항체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096728A (en) * 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
US5747474A (en) * 1996-07-29 1998-05-05 Immune Modulation, Inc. Immunosuppression by administration of N6,N6 -disubstituted cAMP's, analogues thereof, and related nucleosides
US6096731A (en) * 1998-06-24 2000-08-01 Institute For Drug Research, Inc. Method for preventing tissue damage associated with graft-versus-host or host-versus-graft disease following transplantation
US20020086857A1 (en) * 2000-09-15 2002-07-04 Mcdonald George B. Method of long-term treatment of graft-versus-host disease using topical active corticosterioids
IL157921A0 (en) * 2001-03-15 2004-03-28 Enteron Pharmaceuticals Inc Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids
US20030032631A1 (en) * 2001-08-13 2003-02-13 Mcdonald George B. Method of treatment of cancer by controlling graft-versus-leukemia using topical active corticosteriods
JP4014912B2 (ja) * 2001-09-28 2007-11-28 株式会社ルネサステクノロジ 半導体装置

Also Published As

Publication number Publication date
CA2583244A1 (en) 2006-07-06
JP2008526773A (ja) 2008-07-24
EP1830857B1 (en) 2010-09-15
AU2005321826B2 (en) 2012-03-15
DK1830857T3 (da) 2011-02-07
NZ554326A (en) 2010-10-29
CN102218070A (zh) 2011-10-19
WO2006072093A3 (en) 2007-03-22
IL182462A0 (en) 2008-04-13
EP1830857A4 (en) 2008-02-27
US20060252735A1 (en) 2006-11-09
WO2006072093A2 (en) 2006-07-06
CN101060848A (zh) 2007-10-24
AU2005321826A1 (en) 2006-07-06
EP1830857A2 (en) 2007-09-12
CN101060848B (zh) 2011-06-22
DE602005023655D1 (de) 2010-10-28
KR20070089701A (ko) 2007-08-31

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