DE602005019324D1 - Einander ergänzender polynukleotide - Google Patents
Einander ergänzender polynukleotideInfo
- Publication number
- DE602005019324D1 DE602005019324D1 DE602005019324T DE602005019324T DE602005019324D1 DE 602005019324 D1 DE602005019324 D1 DE 602005019324D1 DE 602005019324 T DE602005019324 T DE 602005019324T DE 602005019324 T DE602005019324 T DE 602005019324T DE 602005019324 D1 DE602005019324 D1 DE 602005019324D1
- Authority
- DE
- Germany
- Prior art keywords
- ligation
- ligation product
- complementary
- self
- loop
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63999404P | 2004-12-29 | 2004-12-29 | |
PCT/US2005/045709 WO2006071582A2 (en) | 2004-12-29 | 2005-12-16 | Methods, compositions, and kits for forming self-complementary polynucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005019324D1 true DE602005019324D1 (de) | 2010-03-25 |
Family
ID=36615399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005019324T Active DE602005019324D1 (de) | 2004-12-29 | 2005-12-16 | Einander ergänzender polynukleotide |
Country Status (5)
Country | Link |
---|---|
US (2) | US7169561B2 (de) |
EP (1) | EP1831401B1 (de) |
AT (1) | ATE457363T1 (de) |
DE (1) | DE602005019324D1 (de) |
WO (1) | WO2006071582A2 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7306915B2 (en) * | 2004-03-22 | 2007-12-11 | Sysmex Corporation | Probe set for detection of target substance and detection method using the same |
US7575863B2 (en) * | 2004-05-28 | 2009-08-18 | Applied Biosystems, Llc | Methods, compositions, and kits comprising linker probes for quantifying polynucleotides |
JP2008513028A (ja) * | 2004-09-21 | 2008-05-01 | アプレラ コーポレイション | マイクロRNA(miRNA)の二色リアルタイム/エンドポイント定量化 |
ATE457363T1 (de) * | 2004-12-29 | 2010-02-15 | Applied Biosystems Llc | Verfahren, zusammensetzungen und kits zur bildung einander ergänzender polynukleotide |
US20070128620A1 (en) * | 2005-07-15 | 2007-06-07 | Applera Corporation | Hot start reverse transcription by primer design |
US20070196849A1 (en) * | 2006-02-22 | 2007-08-23 | Applera Corporation | Double-ligation Method for Haplotype and Large-scale Polymorphism Detection |
CA2648702A1 (en) * | 2006-04-04 | 2007-10-11 | Arcxis Biotechnologies, Inc. | Cooperative probes and methods of using them |
US7820389B2 (en) * | 2007-01-10 | 2010-10-26 | Geneohm Sciences, Inc. | Inhibition of mismatch hybridization by a universal competitor DNA |
US20080194416A1 (en) * | 2007-02-08 | 2008-08-14 | Sigma Aldrich | Detection of mature small rna molecules |
US8008010B1 (en) | 2007-06-27 | 2011-08-30 | Applied Biosystems, Llc | Chimeric oligonucleotides for ligation-enhanced nucleic acid detection, methods and compositions therefor |
JP5985390B2 (ja) | 2009-04-02 | 2016-09-06 | フリューダイム・コーポレイション | 標的核酸にバーコードを付加するためのマルチプライマー増幅方法 |
US9200276B2 (en) | 2009-06-01 | 2015-12-01 | Halo-Bio Rnai Therapeutics, Inc. | Polynucleotides for multivalent RNA interference, compositions and methods of use thereof |
CA2772123C (en) * | 2009-08-31 | 2018-03-06 | The Governors Of The University Of Alberta | Binding-induced hairpin detection system |
CN103228796B (zh) * | 2010-08-11 | 2016-06-01 | 赛路拉公司 | 基因分型dna |
US10597701B2 (en) | 2011-05-11 | 2020-03-24 | Navinci Diagnostics Ab | Unfolding proximity probes and methods for the use thereof |
GB201107863D0 (en) * | 2011-05-11 | 2011-06-22 | Olink Ab | Method and product |
CN112592960A (zh) | 2011-05-20 | 2021-04-02 | 富鲁达公司 | 核酸编码反应 |
US20150315597A1 (en) * | 2011-09-01 | 2015-11-05 | New England Biolabs, Inc. | Synthetic Nucleic Acids for Polymerization Reactions |
US9109226B2 (en) * | 2011-09-01 | 2015-08-18 | New England Biolabs, Inc. | Synthetic nucleic acids for polymerization reactions |
DK3129505T3 (en) * | 2014-04-11 | 2021-10-04 | Redvault Biosciences Lp | Methods for clonal replication and amplification of nucleic acid molecules for genomic and therapeutic applications |
US9856521B2 (en) | 2015-01-27 | 2018-01-02 | BioSpyder Technologies, Inc. | Ligation assays in liquid phase |
WO2017035278A1 (en) | 2015-08-24 | 2017-03-02 | Halo-Bio Rnai Therapeutics, Inc. | Polynucleotide nanoparticles for the modulation of gene expression and uses thereof |
EP3390658B1 (de) | 2015-12-16 | 2022-08-03 | Standard BioTools Inc. | High-level-multiplexamplifikation |
US11629345B2 (en) | 2018-06-06 | 2023-04-18 | The Regents Of The University Of California | Methods of producing nucleic acid libraries and compositions and kits for practicing same |
WO2023023484A1 (en) * | 2021-08-16 | 2023-02-23 | 10X Genomics, Inc. | Probes comprising a split barcode region and methods of use |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5215899A (en) * | 1989-11-09 | 1993-06-01 | Miles Inc. | Nucleic acid amplification employing ligatable hairpin probe and transcription |
US5494810A (en) * | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
WO1993017127A1 (en) * | 1992-02-20 | 1993-09-02 | The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University | Boomerand dna amplification |
US5876924A (en) * | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
EP0912761A4 (de) * | 1996-05-29 | 2004-06-09 | Cornell Res Foundation Inc | Bestimmung von unterschieden in der nukleisäuresequenz mittels einer kombination von ligasebestimmung und polymerase-kettenreaktion |
JP3891620B2 (ja) * | 1996-11-14 | 2007-03-14 | 株式会社アイシン・コスモス研究所 | ヘアピン型構造の核酸プローブ分子、及び該核酸プローブ分子を利用した核酸検出方法 |
DK1997909T3 (da) * | 1998-03-25 | 2012-04-23 | Olink Ab | Rullende cirkel-replikation af cirkulariserede målnukleinsyrefragmenter |
US7033753B1 (en) * | 1999-01-15 | 2006-04-25 | University Of Rochester | Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms |
CA2360342A1 (en) * | 1999-12-02 | 2001-06-07 | Molecular Staging Inc. | Generation of single-strand circular dna from linear self-annealing segments |
US6573051B2 (en) * | 2001-03-09 | 2003-06-03 | Molecular Staging, Inc. | Open circle probes with intramolecular stem structures |
JP3829690B2 (ja) * | 2001-10-30 | 2006-10-04 | 株式会社日立製作所 | 核酸配列の検査方法 |
US7452699B2 (en) * | 2003-01-15 | 2008-11-18 | Dana-Farber Cancer Institute, Inc. | Amplification of DNA in a hairpin structure, and applications |
US20040259116A1 (en) * | 2003-01-28 | 2004-12-23 | Gorilla Genomics, Inc. | Hairpin primer amplification |
US20080021205A1 (en) * | 2003-12-11 | 2008-01-24 | Helen Blau | Methods and Compositions for Use in Preparing Hairpin Rnas |
JP4728663B2 (ja) * | 2004-03-22 | 2011-07-20 | シスメックス株式会社 | 標的物質検出用プローブセット及び標的物質検出方法 |
US7306915B2 (en) * | 2004-03-22 | 2007-12-11 | Sysmex Corporation | Probe set for detection of target substance and detection method using the same |
JP2005304489A (ja) * | 2004-03-24 | 2005-11-04 | Sysmex Corp | 標的物質検出用プローブセット及び標的物質検出方法。 |
ATE457363T1 (de) * | 2004-12-29 | 2010-02-15 | Applied Biosystems Llc | Verfahren, zusammensetzungen und kits zur bildung einander ergänzender polynukleotide |
-
2005
- 2005-12-16 AT AT05854429T patent/ATE457363T1/de not_active IP Right Cessation
- 2005-12-16 US US11/305,699 patent/US7169561B2/en not_active Expired - Fee Related
- 2005-12-16 WO PCT/US2005/045709 patent/WO2006071582A2/en active Application Filing
- 2005-12-16 EP EP05854429A patent/EP1831401B1/de not_active Not-in-force
- 2005-12-16 DE DE602005019324T patent/DE602005019324D1/de active Active
-
2007
- 2007-01-12 US US11/622,991 patent/US7588896B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US7169561B2 (en) | 2007-01-30 |
US7588896B2 (en) | 2009-09-15 |
US20060194225A1 (en) | 2006-08-31 |
WO2006071582A3 (en) | 2006-10-19 |
EP1831401B1 (de) | 2010-02-10 |
US20070141610A1 (en) | 2007-06-21 |
WO2006071582A2 (en) | 2006-07-06 |
EP1831401A4 (de) | 2009-02-25 |
EP1831401A2 (de) | 2007-09-12 |
ATE457363T1 (de) | 2010-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |