DE602005009738D1 - Verfahren zur herstellung und sekretion modifizierter peptide - Google Patents

Verfahren zur herstellung und sekretion modifizierter peptide

Info

Publication number
DE602005009738D1
DE602005009738D1 DE602005009738T DE602005009738T DE602005009738D1 DE 602005009738 D1 DE602005009738 D1 DE 602005009738D1 DE 602005009738 T DE602005009738 T DE 602005009738T DE 602005009738 T DE602005009738 T DE 602005009738T DE 602005009738 D1 DE602005009738 D1 DE 602005009738D1
Authority
DE
Germany
Prior art keywords
lantibiotic
host cell
polypeptide
secretion
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005009738T
Other languages
English (en)
Inventor
Gert Nikolaas Moll
Anneke Kuipers
Rick Rink
Arnold Jacob Mathieu Driessen
Oscar Paul Kuipers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Nanosystems BV
Original Assignee
Applied Nanosystems BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Nanosystems BV filed Critical Applied Nanosystems BV
Publication of DE602005009738D1 publication Critical patent/DE602005009738D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602005009738T 2004-12-07 2005-12-07 Verfahren zur herstellung und sekretion modifizierter peptide Active DE602005009738D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04078318 2004-12-07
PCT/NL2005/000842 WO2006062398A2 (en) 2004-12-07 2005-12-07 Methods for the production and secretion of modified peptides

Publications (1)

Publication Number Publication Date
DE602005009738D1 true DE602005009738D1 (de) 2008-10-23

Family

ID=34928712

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005009738T Active DE602005009738D1 (de) 2004-12-07 2005-12-07 Verfahren zur herstellung und sekretion modifizierter peptide

Country Status (8)

Country Link
US (1) US8835616B2 (de)
EP (1) EP1819816B1 (de)
CN (1) CN101115838B (de)
AT (1) ATE408016T1 (de)
CA (1) CA2594151C (de)
DE (1) DE602005009738D1 (de)
DK (1) DK1819816T3 (de)
WO (1) WO2006062398A2 (de)

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US8563527B2 (en) 2007-08-20 2013-10-22 Pharmain Corporation Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same
SG173504A1 (en) * 2009-02-04 2011-09-29 Novacta Biosystems Ltd Actagardine derivatives
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EP2405008A1 (de) 2010-07-06 2012-01-11 LanthioPep B.V. Bakterienoberflächenanzeige von thioether-brücken-haltigen Peptiden
WO2012019928A1 (en) 2010-08-13 2012-02-16 Guntram Christiansen Modified peptide display
AU2015371172B2 (en) 2014-12-22 2021-05-13 Lanthiopep B.V. Novel methods for displaying cyclic peptides on bacteriophage particles
EP3268383B1 (de) * 2015-03-13 2021-12-01 LanthioPep B.V. Cyclische galaninanaloga und verwendungen davon
WO2016180928A1 (en) * 2015-05-12 2016-11-17 Novozymes A/S Bacillus licheniformis host cell with deleted lantibiotic gene(s)
CN106755220A (zh) * 2015-11-23 2017-05-31 武汉臻智生物科技有限公司 制备乳酸链球菌素的方法
US20190144908A1 (en) * 2016-06-10 2019-05-16 White Dog Labs, Inc. High cell density anaerobic fermentation for protein expression
CN113354718B (zh) * 2021-06-21 2023-06-02 重庆市畜牧科学院 一种哌尼生素前体、表达盒及其制备方法

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US7785825B2 (en) 2004-01-12 2010-08-31 The Board Of Trustees Of The University Of Illinois Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics
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Also Published As

Publication number Publication date
US20090042246A1 (en) 2009-02-12
DK1819816T3 (da) 2009-01-26
EP1819816A2 (de) 2007-08-22
EP1819816B1 (de) 2008-09-10
CN101115838B (zh) 2015-08-12
WO2006062398A2 (en) 2006-06-15
ATE408016T1 (de) 2008-09-15
US8835616B2 (en) 2014-09-16
CN101115838A (zh) 2008-01-30
CA2594151A1 (en) 2006-06-15
CA2594151C (en) 2013-02-19
WO2006062398A3 (en) 2006-10-19

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