DE602005009693D1 - 2"-nitrobenzyl-modifizierte ribonukleotide - Google Patents

2"-nitrobenzyl-modifizierte ribonukleotide

Info

Publication number
DE602005009693D1
DE602005009693D1 DE602005009693T DE602005009693T DE602005009693D1 DE 602005009693 D1 DE602005009693 D1 DE 602005009693D1 DE 602005009693 T DE602005009693 T DE 602005009693T DE 602005009693 T DE602005009693 T DE 602005009693T DE 602005009693 D1 DE602005009693 D1 DE 602005009693D1
Authority
DE
Germany
Prior art keywords
nitrobenzyl
modified ribonucleotide
reagent
methods
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602005009693T
Other languages
German (de)
English (en)
Inventor
Olaf Piepenburg
Derek L Stemple
Niall A Armes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TwistDix Inc
Original Assignee
TwistDix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TwistDix Inc filed Critical TwistDix Inc
Publication of DE602005009693D1 publication Critical patent/DE602005009693D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE602005009693T 2004-06-02 2005-06-02 2"-nitrobenzyl-modifizierte ribonukleotide Expired - Fee Related DE602005009693D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57690704P 2004-06-02 2004-06-02
PCT/IB2005/002488 WO2005118608A2 (en) 2004-06-02 2005-06-02 2’-nitrobenzyl-modified ribonucleotides

Publications (1)

Publication Number Publication Date
DE602005009693D1 true DE602005009693D1 (de) 2008-10-23

Family

ID=35463420

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005009693T Expired - Fee Related DE602005009693D1 (de) 2004-06-02 2005-06-02 2"-nitrobenzyl-modifizierte ribonukleotide

Country Status (8)

Country Link
US (4) US7759061B2 (https=)
EP (1) EP1753774B1 (https=)
JP (3) JP2008501679A (https=)
AT (1) ATE407939T1 (https=)
AU (1) AU2005250239A1 (https=)
CA (1) CA2569491A1 (https=)
DE (1) DE602005009693D1 (https=)
WO (1) WO2005118608A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572581B2 (en) 2003-06-30 2009-08-11 Roche Molecular Systems, Inc. 2′-terminator nucleotide-related methods and systems
US7947817B2 (en) 2003-06-30 2011-05-24 Roche Molecular Systems, Inc. Synthesis and compositions of 2'-terminator nucleotides
AU2005250239A1 (en) * 2004-06-02 2005-12-15 Alere San Diego, Inc. 2'-nitrobenzyl-modified ribonucleotides
US7745125B2 (en) 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
US7928207B2 (en) 2004-06-28 2011-04-19 Roche Molecular Systems, Inc Synthesis and compositions of nucleic acids comprising 2′-terminator nucleotides
ES2388722T3 (es) * 2005-12-21 2012-10-18 F. Hoffmann-La Roche Ag Secuenciación y genotipado utilizando nucleótidos modificados en 2' de forma reversible
WO2008042067A2 (en) 2006-09-28 2008-04-10 Illumina, Inc. Compositions and methods for nucleotide sequencing
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
CN108051590B (zh) 2013-09-13 2020-12-11 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
CN105722977A (zh) 2013-10-30 2016-06-29 绿色生活生物技术有限责任公司 用于柑橘绿化枯萎病的发病定量系统和治疗方法
CA3218077A1 (en) 2021-04-29 2022-11-03 Abbott Laboratories Systems and methods for pooling samples for high-throughput analysis

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58109498A (ja) * 1981-08-24 1983-06-29 Agency Of Ind Science & Technol オリゴリボヌクレオチド
JPS5836396A (ja) * 1981-08-24 1983-03-03 Agency Of Ind Science & Technol オリゴリボヌクレオチドの製造法
US5223414A (en) 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
CA2122203C (en) 1993-05-11 2001-12-18 Melinda S. Fraiser Decontamination of nucleic acid amplification reactions
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US6136543A (en) * 1997-01-31 2000-10-24 Hitachi, Ltd. Method for determining nucleic acids base sequence and apparatus therefor
WO2000053805A1 (en) * 1999-03-10 2000-09-14 Asm Scientific, Inc. A method for direct nucleic acid sequencing
JP2001288197A (ja) * 2000-04-10 2001-10-16 Fuji Photo Film Co Ltd 蛍光ヌクレオチド
AU2001296645A1 (en) * 2000-10-06 2002-04-15 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding dna and rna
CN1348096A (zh) * 2000-10-10 2002-05-08 栾国彦 一种均相特异性检测核酸的探针及应用方法
EP1317464B1 (en) * 2000-10-11 2009-05-13 Applera Corporation Fluorescent nucleobase conjugates having anionic linkers
US7270981B2 (en) 2002-02-21 2007-09-18 Asm Scientific, Inc. Recombinase polymerase amplification
EP3985125A1 (en) 2004-06-01 2022-04-20 Abbott Diagnostics Scarborough, Inc. Recombinase polymerase amplification
AU2005250239A1 (en) * 2004-06-02 2005-12-15 Alere San Diego, Inc. 2'-nitrobenzyl-modified ribonucleotides

Also Published As

Publication number Publication date
ATE407939T1 (de) 2008-09-15
CA2569491A1 (en) 2005-12-15
US20130045475A1 (en) 2013-02-21
US8299226B2 (en) 2012-10-30
WO2005118608A3 (en) 2006-04-27
EP1753774B1 (en) 2008-09-10
WO2005118608A2 (en) 2005-12-15
US7759061B2 (en) 2010-07-20
US8022194B2 (en) 2011-09-20
JP2008501679A (ja) 2008-01-24
EP1753774A2 (en) 2007-02-21
US20080261208A1 (en) 2008-10-23
AU2005250239A1 (en) 2005-12-15
US20110053154A1 (en) 2011-03-03
JP2012157369A (ja) 2012-08-23
JP2012095665A (ja) 2012-05-24
US20120040345A1 (en) 2012-02-16

Similar Documents

Publication Publication Date Title
WO2007075967A3 (en) Sequencing and genotyping using reversibly 2'-modified nucleotides
ATE356222T1 (de) Massives parallelverfahren zur dekodierung von dna und rna
DE602005009693D1 (de) 2"-nitrobenzyl-modifizierte ribonukleotide
WO2007041342A3 (en) Labeled nucleotide analogs and uses therefor
DE60127469D1 (de) Potentiometrischer dna-mikroarray, verfahren zu dessen herstellung und verfahren zur nukleinsäureanalyse
GEP20125384B (en) Representations of nucleotide sequences
ATE550441T1 (de) Verfahren, zusammensetzungen und kits zur isothermischen amplifikation von nukleinsäuren
WO2010117420A3 (en) Fret-labeled compounds and uses therefor
ATE551349T1 (de) Methode unter verwendung von reversibel blockierten markierungsoligonukleotiden
AU2003299541A8 (en) Microfluidic nucleic acid analysis
DE60320780D1 (de) Funktionalisierte nanopartikel und verwendungsverfahren
AU2003900368A0 (en) Assay for nucleic acid molecules
DK2725107T3 (da) DNA-sekventering med ikke-fluorescerende nukleotidreversible terminatorer og ddNTP'er modificeret med spaltbart mærke og nukleinsyre omfattende inosin med reversible terminatorer
EP2514826A3 (en) Use of interfering RNA molecules to down regulate the expression of specific genes or family of genes
EP2004852A4 (en) AMPLIFICATION OF DNA FRAGMENTS
WO2005030984A3 (en) Method for small volume nucleic acid synthesis
WO2005021786A8 (en) A method of sequencing nucleic acids by ligation of labelled oligonucleotides
GB0508052D0 (en) Method to generate or determine nucleic acid tags corresponding the the terminal ends of DNA molecules using sequences analysis of gene expression
ATE541056T1 (de) Verwendung von dna-polymerasen wie exoribonukleasen
WO2007057167A3 (en) A method for enhancing enzymatic dna polymerase reactions
AU2002346498A8 (en) Thermus brockianus nucleic acid polymerases
WO2003093429A3 (en) Nucleic acid reactions using labels with different redox potentials
DE60324253D1 (de) Spezifische multiplex-analyse von nukleinsäuren
GB0406863D0 (en) Nucleic acid sequencing
DE602006018701D1 (de) Polypeptide mit nukleinsäurebindender aktivität

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee