DE602005009693D1 - 2"-nitrobenzyl-modifizierte ribonukleotide - Google Patents
2"-nitrobenzyl-modifizierte ribonukleotideInfo
- Publication number
- DE602005009693D1 DE602005009693D1 DE602005009693T DE602005009693T DE602005009693D1 DE 602005009693 D1 DE602005009693 D1 DE 602005009693D1 DE 602005009693 T DE602005009693 T DE 602005009693T DE 602005009693 T DE602005009693 T DE 602005009693T DE 602005009693 D1 DE602005009693 D1 DE 602005009693D1
- Authority
- DE
- Germany
- Prior art keywords
- nitrobenzyl
- modified ribonucleotide
- reagent
- methods
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108091028664 Ribonucleotide Proteins 0.000 title abstract 2
- 239000002336 ribonucleotide Substances 0.000 title abstract 2
- 238000001712 DNA sequencing Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 125000002652 ribonucleotide group Chemical group 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57690704P | 2004-06-02 | 2004-06-02 | |
| PCT/IB2005/002488 WO2005118608A2 (en) | 2004-06-02 | 2005-06-02 | 2’-nitrobenzyl-modified ribonucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005009693D1 true DE602005009693D1 (de) | 2008-10-23 |
Family
ID=35463420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005009693T Expired - Fee Related DE602005009693D1 (de) | 2004-06-02 | 2005-06-02 | 2"-nitrobenzyl-modifizierte ribonukleotide |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7759061B2 (https=) |
| EP (1) | EP1753774B1 (https=) |
| JP (3) | JP2008501679A (https=) |
| AT (1) | ATE407939T1 (https=) |
| AU (1) | AU2005250239A1 (https=) |
| CA (1) | CA2569491A1 (https=) |
| DE (1) | DE602005009693D1 (https=) |
| WO (1) | WO2005118608A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7947817B2 (en) | 2003-06-30 | 2011-05-24 | Roche Molecular Systems, Inc. | Synthesis and compositions of 2'-terminator nucleotides |
| US7572581B2 (en) | 2003-06-30 | 2009-08-11 | Roche Molecular Systems, Inc. | 2′-terminator nucleotide-related methods and systems |
| AU2005250239A1 (en) * | 2004-06-02 | 2005-12-15 | Alere San Diego, Inc. | 2'-nitrobenzyl-modified ribonucleotides |
| US7928207B2 (en) * | 2004-06-28 | 2011-04-19 | Roche Molecular Systems, Inc | Synthesis and compositions of nucleic acids comprising 2′-terminator nucleotides |
| US7745125B2 (en) | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| CN101346472B (zh) * | 2005-12-21 | 2013-04-24 | 霍夫曼—拉罗奇有限公司 | 用可逆2’-修饰的核苷酸进行的序列测定和基因分型 |
| US8399188B2 (en) | 2006-09-28 | 2013-03-19 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
| US8486717B2 (en) | 2011-01-18 | 2013-07-16 | Symbolics, Llc | Lateral flow assays using two dimensional features |
| US9874556B2 (en) | 2012-07-18 | 2018-01-23 | Symbolics, Llc | Lateral flow assays using two dimensional features |
| US9146248B2 (en) | 2013-03-14 | 2015-09-29 | Intelligent Bio-Systems, Inc. | Apparatus and methods for purging flow cells in nucleic acid sequencing instruments |
| US9591268B2 (en) | 2013-03-15 | 2017-03-07 | Qiagen Waltham, Inc. | Flow cell alignment methods and systems |
| EP3044592B1 (en) | 2013-09-13 | 2019-07-17 | Symbolics, LLC | Lateral flow assays using two dimensional test and control signal readout patterns |
| CN105722977A (zh) | 2013-10-30 | 2016-06-29 | 绿色生活生物技术有限责任公司 | 用于柑橘绿化枯萎病的发病定量系统和治疗方法 |
| JP2024518331A (ja) | 2021-04-29 | 2024-05-01 | アボット・ラボラトリーズ | 生体試料のハイスループット核酸検査 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58109498A (ja) * | 1981-08-24 | 1983-06-29 | Agency Of Ind Science & Technol | オリゴリボヌクレオチド |
| JPS5836396A (ja) * | 1981-08-24 | 1983-03-03 | Agency Of Ind Science & Technol | オリゴリボヌクレオチドの製造法 |
| US5223414A (en) | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| CA2122203C (en) * | 1993-05-11 | 2001-12-18 | Melinda S. Fraiser | Decontamination of nucleic acid amplification reactions |
| US20010018514A1 (en) * | 1998-07-31 | 2001-08-30 | Mcgall Glenn H. | Nucleic acid labeling compounds |
| WO1998033939A1 (en) * | 1997-01-31 | 1998-08-06 | Hitachi, Ltd. | Method for determining nucleic acid base sequence and apparatus therefor |
| AU3174600A (en) * | 1999-03-10 | 2000-09-28 | Asm Scientific, Inc. | A method for direct nucleic acid sequencing |
| JP2001288197A (ja) * | 2000-04-10 | 2001-10-16 | Fuji Photo Film Co Ltd | 蛍光ヌクレオチド |
| JP2004510433A (ja) * | 2000-10-06 | 2004-04-08 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | Ｄｎａおよびｒｎａを解読するための大量並行方法 |
| CN1348096A (zh) * | 2000-10-10 | 2002-05-08 | 栾国彦 | 一种均相特异性检测核酸的探针及应用方法 |
| AU1312502A (en) * | 2000-10-11 | 2002-04-22 | Pe Corp Ny | Fluorescent nucleobase conjugates having anionic linkers |
| DE60322044D1 (de) | 2002-02-21 | 2008-08-21 | Asm Scient Inc | Rekombinase-polymerase-amplifikation |
| ES2425354T3 (es) | 2004-06-01 | 2013-10-14 | Alere San Diego, Inc. | Amplificación por recombinasa-polimerasa |
| AU2005250239A1 (en) * | 2004-06-02 | 2005-12-15 | Alere San Diego, Inc. | 2'-nitrobenzyl-modified ribonucleotides |
-
2005
- 2005-06-02 AU AU2005250239A patent/AU2005250239A1/en not_active Abandoned
- 2005-06-02 DE DE602005009693T patent/DE602005009693D1/de not_active Expired - Fee Related
- 2005-06-02 US US11/628,343 patent/US7759061B2/en active Active
- 2005-06-02 AT AT05769767T patent/ATE407939T1/de not_active IP Right Cessation
- 2005-06-02 CA CA002569491A patent/CA2569491A1/en not_active Abandoned
- 2005-06-02 WO PCT/IB2005/002488 patent/WO2005118608A2/en not_active Ceased
- 2005-06-02 JP JP2007514217A patent/JP2008501679A/ja not_active Withdrawn
- 2005-06-02 EP EP05769767A patent/EP1753774B1/en not_active Expired - Lifetime
-
2010
- 2010-06-21 US US12/803,261 patent/US8022194B2/en not_active Expired - Lifetime
-
2011
- 2011-08-10 US US13/206,926 patent/US8299226B2/en not_active Expired - Lifetime
-
2012
- 2012-01-25 JP JP2012013260A patent/JP2012095665A/ja active Pending
- 2012-05-25 JP JP2012119854A patent/JP2012157369A/ja active Pending
- 2012-10-23 US US13/658,023 patent/US20130045475A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008501679A (ja) | 2008-01-24 |
| JP2012157369A (ja) | 2012-08-23 |
| US8299226B2 (en) | 2012-10-30 |
| CA2569491A1 (en) | 2005-12-15 |
| US20130045475A1 (en) | 2013-02-21 |
| US20110053154A1 (en) | 2011-03-03 |
| JP2012095665A (ja) | 2012-05-24 |
| US20120040345A1 (en) | 2012-02-16 |
| EP1753774B1 (en) | 2008-09-10 |
| ATE407939T1 (de) | 2008-09-15 |
| WO2005118608A2 (en) | 2005-12-15 |
| US20080261208A1 (en) | 2008-10-23 |
| EP1753774A2 (en) | 2007-02-21 |
| US7759061B2 (en) | 2010-07-20 |
| AU2005250239A1 (en) | 2005-12-15 |
| US8022194B2 (en) | 2011-09-20 |
| WO2005118608A3 (en) | 2006-04-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2007075967A3 (en) | Sequencing and genotyping using reversibly 2'-modified nucleotides | |
| DE60127162D1 (de) | Massives Parallelverfahren zur Dekodierung von DNA und RNA | |
| DE602005009693D1 (de) | 2"-nitrobenzyl-modifizierte ribonukleotide | |
| WO2007041342A3 (en) | Labeled nucleotide analogs and uses therefor | |
| DE60127469D1 (de) | Potentiometrischer dna-mikroarray, verfahren zu dessen herstellung und verfahren zur nukleinsäureanalyse | |
| GEP20125384B (en) | Representations of nucleotide sequences | |
| ATE550441T1 (de) | Verfahren, zusammensetzungen und kits zur isothermischen amplifikation von nukleinsäuren | |
| WO2010117420A3 (en) | Fret-labeled compounds and uses therefor | |
| ATE551349T1 (de) | Methode unter verwendung von reversibel blockierten markierungsoligonukleotiden | |
| AU2003900368A0 (en) | Assay for nucleic acid molecules | |
| DK2725107T3 (da) | DNA-sekventering med ikke-fluorescerende nukleotidreversible terminatorer og ddNTP'er modificeret med spaltbart mærke og nukleinsyre omfattende inosin med reversible terminatorer | |
| DK2253718T3 (da) | Fast overflade til biomolekylafgivelse og analyse med høj omsætning | |
| WO2005059108A3 (en) | Gene expression profiles and methods of use | |
| EP2004852A4 (en) | AMPLIFICATION OF DNA FRAGMENTS | |
| WO2005030984A3 (en) | Method for small volume nucleic acid synthesis | |
| DE602004023631D1 (de) | Verfahren zur einführung einer nukleinsäure | |
| GB0508052D0 (en) | Method to generate or determine nucleic acid tags corresponding the the terminal ends of DNA molecules using sequences analysis of gene expression | |
| WO2007057167A3 (en) | A method for enhancing enzymatic dna polymerase reactions | |
| AU2002346498A8 (en) | Thermus brockianus nucleic acid polymerases | |
| ATE541056T1 (de) | Verwendung von dna-polymerasen wie exoribonukleasen | |
| WO2003093429A3 (en) | Nucleic acid reactions using labels with different redox potentials | |
| DE60324253D1 (de) | Spezifische multiplex-analyse von nukleinsäuren | |
| GB0406863D0 (en) | Nucleic acid sequencing | |
| DE602006018701D1 (de) | Polypeptide mit nukleinsäurebindender aktivität | |
| WO2002046468A3 (en) | Method for maldi-tof-ms analysis and/or sequencing of oligonucleotides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |