DE602005002750D1 - Chirale heptinderivate zur herstellung von epothilonen und verfahren zu deren herstellung - Google Patents
Chirale heptinderivate zur herstellung von epothilonen und verfahren zu deren herstellungInfo
- Publication number
- DE602005002750D1 DE602005002750D1 DE602005002750T DE602005002750T DE602005002750D1 DE 602005002750 D1 DE602005002750 D1 DE 602005002750D1 DE 602005002750 T DE602005002750 T DE 602005002750T DE 602005002750 T DE602005002750 T DE 602005002750T DE 602005002750 D1 DE602005002750 D1 DE 602005002750D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- epothilones
- derivatives
- heptin
- chiral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04090157A EP1589011A1 (de) | 2004-04-22 | 2004-04-22 | Neue chirale Heptin Derivate zur Herstellung von Epothilonen und Verfahren zu deren Herstellung |
EP04090157 | 2004-04-22 | ||
US56584904P | 2004-04-28 | 2004-04-28 | |
US565849P | 2004-04-28 | ||
PCT/EP2005/004492 WO2005101950A1 (en) | 2004-04-22 | 2005-04-21 | Chiral heptyne derivatives for the preparation of epothilones and processes for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602005002750D1 true DE602005002750D1 (de) | 2007-11-15 |
DE602005002750T2 DE602005002750T2 (de) | 2008-07-17 |
Family
ID=34928801
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005002750T Active DE602005002750T2 (de) | 2004-04-22 | 2005-04-21 | Chirale heptinderivate zur herstellung von epothilonen und verfahren zu deren herstellung |
Country Status (18)
Country | Link |
---|---|
US (2) | US7326798B2 (de) |
EP (2) | EP1589011A1 (de) |
JP (1) | JP2007533700A (de) |
CN (1) | CN1942462B (de) |
AT (1) | ATE374758T1 (de) |
AU (1) | AU2005235376A1 (de) |
BR (1) | BRPI0510109A (de) |
CA (1) | CA2560455A1 (de) |
DE (1) | DE602005002750T2 (de) |
DK (1) | DK1758875T3 (de) |
ES (1) | ES2293574T3 (de) |
MX (1) | MXPA06012212A (de) |
PL (1) | PL1758875T3 (de) |
PT (1) | PT1758875E (de) |
RU (1) | RU2006140967A (de) |
SI (1) | SI1758875T1 (de) |
WO (1) | WO2005101950A1 (de) |
ZA (1) | ZA200609677B (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8026081B2 (en) | 2006-03-28 | 2011-09-27 | Sumitomo Chemical Company, Limited | Method of producing optically active (S)-7-hydroxy-6-methylheptan-2-one and precursor thereof |
CN104758089B (zh) | 2014-01-08 | 2018-03-30 | 库克医学技术有限责任公司 | 用于塞住经皮心脏瓣膜泄漏的ecm条带 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6320045B1 (en) * | 1997-12-04 | 2001-11-20 | Bristol-Myers Squibb Company | Process for the reduction of oxiranyl epothilones to olefinic epothilones |
GB9810659D0 (en) | 1998-05-18 | 1998-07-15 | Ciba Geigy Ag | Organic compounds |
IL144370A0 (en) * | 1999-02-11 | 2002-05-23 | Schering Ag | Epothilon derivatives, method for the production and the use thereof as pharmaceuticals |
US6593115B2 (en) | 2000-03-24 | 2003-07-15 | Bristol-Myers Squibb Co. | Preparation of epothilone intermediates |
-
2004
- 2004-04-22 EP EP04090157A patent/EP1589011A1/de not_active Withdrawn
-
2005
- 2005-04-21 MX MXPA06012212A patent/MXPA06012212A/es not_active Application Discontinuation
- 2005-04-21 CA CA002560455A patent/CA2560455A1/en not_active Abandoned
- 2005-04-21 WO PCT/EP2005/004492 patent/WO2005101950A1/en active Application Filing
- 2005-04-21 EP EP05740374A patent/EP1758875B1/de active Active
- 2005-04-21 SI SI200530107T patent/SI1758875T1/sl unknown
- 2005-04-21 DK DK05740374T patent/DK1758875T3/da active
- 2005-04-21 AT AT05740374T patent/ATE374758T1/de not_active IP Right Cessation
- 2005-04-21 US US11/110,959 patent/US7326798B2/en not_active Expired - Fee Related
- 2005-04-21 RU RU2006140967/04A patent/RU2006140967A/ru not_active Application Discontinuation
- 2005-04-21 AU AU2005235376A patent/AU2005235376A1/en not_active Abandoned
- 2005-04-21 PL PL05740374T patent/PL1758875T3/pl unknown
- 2005-04-21 JP JP2007508870A patent/JP2007533700A/ja active Pending
- 2005-04-21 DE DE602005002750T patent/DE602005002750T2/de active Active
- 2005-04-21 ES ES05740374T patent/ES2293574T3/es active Active
- 2005-04-21 CN CN2005800116115A patent/CN1942462B/zh not_active Expired - Fee Related
- 2005-04-21 PT PT05740374T patent/PT1758875E/pt unknown
- 2005-04-21 BR BRPI0510109-3A patent/BRPI0510109A/pt not_active IP Right Cessation
-
2006
- 2006-11-21 ZA ZA200609677A patent/ZA200609677B/en unknown
-
2007
- 2007-12-12 US US11/954,348 patent/US20080108838A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ZA200609677B (en) | 2008-01-30 |
EP1758875B1 (de) | 2007-10-03 |
PL1758875T3 (pl) | 2008-02-29 |
WO2005101950A1 (en) | 2005-11-03 |
ES2293574T3 (es) | 2008-03-16 |
US20060100442A1 (en) | 2006-05-11 |
EP1589011A1 (de) | 2005-10-26 |
CA2560455A1 (en) | 2005-11-03 |
CN1942462B (zh) | 2011-05-25 |
PT1758875E (pt) | 2007-12-14 |
DE602005002750T2 (de) | 2008-07-17 |
MXPA06012212A (es) | 2007-04-17 |
ATE374758T1 (de) | 2007-10-15 |
US7326798B2 (en) | 2008-02-05 |
DK1758875T3 (da) | 2008-01-21 |
EP1758875A1 (de) | 2007-03-07 |
AU2005235376A1 (en) | 2005-11-03 |
JP2007533700A (ja) | 2007-11-22 |
US20080108838A1 (en) | 2008-05-08 |
SI1758875T1 (sl) | 2008-02-29 |
RU2006140967A (ru) | 2008-05-27 |
CN1942462A (zh) | 2007-04-04 |
BRPI0510109A (pt) | 2007-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |