DE602004029897D1 - Herstellung von thiamin durch fermentation - Google Patents

Herstellung von thiamin durch fermentation

Info

Publication number
DE602004029897D1
DE602004029897D1 DE602004029897T DE602004029897T DE602004029897D1 DE 602004029897 D1 DE602004029897 D1 DE 602004029897D1 DE 602004029897 T DE602004029897 T DE 602004029897T DE 602004029897 T DE602004029897 T DE 602004029897T DE 602004029897 D1 DE602004029897 D1 DE 602004029897D1
Authority
DE
Germany
Prior art keywords
assays
products
thiamin
thiamine
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004029897T
Other languages
English (en)
Inventor
Markus Guenter Goese
John B Perkins
Ghislain Schyns
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE602004029897D1 publication Critical patent/DE602004029897D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/167—Heterorings having sulfur atoms as ring heteroatoms, e.g. vitamin B1, thiamine nucleus and open chain analogs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602004029897T 2003-06-02 2004-05-27 Herstellung von thiamin durch fermentation Expired - Lifetime DE602004029897D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47532303P 2003-06-02 2003-06-02
PCT/CH2004/000321 WO2004106557A2 (en) 2003-06-02 2004-05-27 Thiamin production by fermentation

Publications (1)

Publication Number Publication Date
DE602004029897D1 true DE602004029897D1 (de) 2010-12-16

Family

ID=33490751

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004029897T Expired - Lifetime DE602004029897D1 (de) 2003-06-02 2004-05-27 Herstellung von thiamin durch fermentation

Country Status (8)

Country Link
US (2) US20060127993A1 (de)
EP (1) EP1651780B1 (de)
JP (1) JP4695068B2 (de)
KR (1) KR20060006846A (de)
CN (1) CN1894424B (de)
AT (1) ATE486967T1 (de)
DE (1) DE602004029897D1 (de)
WO (1) WO2004106557A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100857379B1 (ko) 2007-01-11 2008-09-11 씨제이제일제당 (주) 포스포라이보실 아미노이미다졸 카복실라아제가 과발현된미생물 및 이를 이용한 5'-이노신산의 생산 방법
EP2186880A1 (de) 2008-11-07 2010-05-19 DSM IP Assets B.V. Verbesserte Riboflavin-Produktion
WO2012032522A1 (en) 2010-09-07 2012-03-15 Yeda Research And Development Co. Ltd. Thiamine pyrophosphate (tpp) riboswitch mutants producing vitamin b1 enriched food and feed crops
US20120107888A1 (en) * 2011-02-17 2012-05-03 Qteros, Inc. Modulation of fermentation products through vitamin supplementation
CN108884435A (zh) * 2015-12-18 2018-11-23 比奥森蒂亚有限公司 用于硫胺素生产的基因修饰型细菌细胞工厂
CN110869384A (zh) * 2017-07-14 2020-03-06 毒菌公司 具有改善的铁硫簇递送的细胞工厂
CN108011094B (zh) * 2017-11-10 2020-08-04 上海交通大学 一种锂硫电池复合正极材料的制备方法
CN110468092B (zh) * 2019-08-26 2021-10-01 天津科技大学 一株高产l-缬氨酸的基因工程菌及其构建方法与应用
EP4294209A1 (de) 2021-02-22 2023-12-27 Symrise AG Biotechnologische herstellung fleischähnlicher aromastoffe
WO2024013212A1 (en) * 2022-07-15 2024-01-18 Biosyntia Aps Microbial cell factories producing thiamine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03210190A (ja) * 1989-09-04 1991-09-13 Kyowa Hakko Kogyo Co Ltd チアミンリン酸類の製造法

Also Published As

Publication number Publication date
WO2004106557A2 (en) 2004-12-09
US20060127993A1 (en) 2006-06-15
JP4695068B2 (ja) 2011-06-08
US20090233296A1 (en) 2009-09-17
EP1651780A2 (de) 2006-05-03
WO2004106557A3 (en) 2005-09-01
KR20060006846A (ko) 2006-01-19
US8329395B2 (en) 2012-12-11
ATE486967T1 (de) 2010-11-15
CN1894424B (zh) 2012-05-23
JP2006526395A (ja) 2006-11-24
EP1651780B1 (de) 2010-11-03
CN1894424A (zh) 2007-01-10

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