DE602004025371D1 - Nukleinsäurenachweisverfahren mit erhöhter empfindlichkeit - Google Patents

Nukleinsäurenachweisverfahren mit erhöhter empfindlichkeit

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Publication number
DE602004025371D1
DE602004025371D1 DE602004025371T DE602004025371T DE602004025371D1 DE 602004025371 D1 DE602004025371 D1 DE 602004025371D1 DE 602004025371 T DE602004025371 T DE 602004025371T DE 602004025371 T DE602004025371 T DE 602004025371T DE 602004025371 D1 DE602004025371 D1 DE 602004025371D1
Authority
DE
Germany
Prior art keywords
nucleic acid
detection method
acid detection
increased sensitivity
technique involves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004025371T
Other languages
English (en)
Inventor
Donald M Crothers
Erik R Holmlin
Honghua Zhang
Chunnian Shi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GeneOhm Sciences Inc
Original Assignee
GeneOhm Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GeneOhm Sciences Inc filed Critical GeneOhm Sciences Inc
Publication of DE602004025371D1 publication Critical patent/DE602004025371D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
DE602004025371T 2003-11-10 2004-11-10 Nukleinsäurenachweisverfahren mit erhöhter empfindlichkeit Active DE602004025371D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51881603P 2003-11-10 2003-11-10
PCT/US2004/037407 WO2005047474A2 (en) 2003-11-10 2004-11-10 Nucleic acid detection method having increased sensitivity

Publications (1)

Publication Number Publication Date
DE602004025371D1 true DE602004025371D1 (de) 2010-03-18

Family

ID=34590306

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004025371T Active DE602004025371D1 (de) 2003-11-10 2004-11-10 Nukleinsäurenachweisverfahren mit erhöhter empfindlichkeit

Country Status (8)

Country Link
US (1) US20050186590A1 (de)
EP (2) EP1687406B1 (de)
JP (1) JP4947355B2 (de)
AT (1) ATE456678T1 (de)
AU (1) AU2004290036B2 (de)
CA (1) CA2545356A1 (de)
DE (1) DE602004025371D1 (de)
WO (1) WO2005047474A2 (de)

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US7910719B2 (en) * 2005-12-08 2011-03-22 Kabushiki Kaisha Toshiba Method of detecting human papilloma virus by using nucleic acid amplification method and nucleic acid chain-immobilized carrier
RU2008148143A (ru) * 2006-06-08 2010-06-10 Конинклейке Филипс Электроникс Н.В. (Nl) Микроэлектронное сенсорное устройство для детектирования днк
DE102006027675B4 (de) 2006-06-14 2011-05-12 Siemens Ag Verfahren zur Bestimmung der Konzentration von Nukleinsäuren
EP2639579B1 (de) 2006-12-14 2016-11-16 Life Technologies Corporation Vorrichtung zur Messung von Analyten mithilfe großer FET-Arrays
EP2395113A1 (de) 2007-06-29 2011-12-14 Population Genetics Technologies Ltd. Verfahren und Zusammensetzungen zur Isolierung von Nukleinsäuresequenzvarianten
US9551026B2 (en) * 2007-12-03 2017-01-24 Complete Genomincs, Inc. Method for nucleic acid detection using voltage enhancement
ES2732948T3 (es) 2008-09-02 2019-11-26 Governing Council Univ Toronto Métodos que utilizan microelectrodos y dispositivos biosensores que incorporan los mismos
CN102301228A (zh) * 2008-10-22 2011-12-28 生命技术公司 用于生物和化学分析的集成式传感器阵列
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US20100133118A1 (en) * 2008-11-24 2010-06-03 Adnavance Technologies, Inc. Electrochemical methods of detecting nucleic acid hybridization
US8776573B2 (en) 2009-05-29 2014-07-15 Life Technologies Corporation Methods and apparatus for measuring analytes
CN103154718B (zh) 2010-06-30 2015-09-23 生命科技公司 感测离子的电荷堆积电路和方法
WO2012097081A2 (en) 2011-01-11 2012-07-19 The Governing Council Of The University Of Toronto Protein detection method
US9580742B2 (en) 2011-03-10 2017-02-28 Shana O. Kelley Diagnostic and sample preparation devices and methods
US10837879B2 (en) 2011-11-02 2020-11-17 Complete Genomics, Inc. Treatment for stabilizing nucleic acid arrays
US9970984B2 (en) 2011-12-01 2018-05-15 Life Technologies Corporation Method and apparatus for identifying defects in a chemical sensor array
US20150045249A1 (en) * 2012-02-27 2015-02-12 Toray Industries, Inc. Nucleic acid detection method
CN104919057B (zh) * 2012-11-14 2018-09-25 欧凌科公司 基于rca的局部扩增方法
US10458942B2 (en) 2013-06-10 2019-10-29 Life Technologies Corporation Chemical sensor array having multiple sensors per well
EP3030678A4 (de) * 2013-08-07 2017-05-10 Xagenic, Inc. Systeme, verfahren und vorrichtungen für elektrochemische detektion mithilfe von helper-oligonukleotiden
JP6385356B2 (ja) * 2013-10-25 2018-09-05 一般財団法人生産技術研究奨励会 Ｄｎａの検出方法
EP3234576B1 (de) 2014-12-18 2023-11-22 Life Technologies Corporation Integrierte schaltung mit hoher datenrate und mit transmitterkonfiguration
GB201614023D0 (en) 2016-08-16 2016-09-28 Olink Bioscience Ab Double-stranded circle probes
CN112400016A (zh) * 2018-06-26 2021-02-23 Tdk株式会社 用于检测dna的试剂盒与方法
JP7333928B2 (ja) * 2018-10-05 2023-08-28 国立大学法人山形大学 電気化学式非標識核酸検出の測定方法

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CN1617936A (zh) * 2002-01-29 2005-05-18 美国大西洋生物实验室 在单一样本中检测和定量多种靶核酸
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US7258978B2 (en) * 2002-11-06 2007-08-21 Geneohm Sciences Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen
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Also Published As

Publication number Publication date
AU2004290036A1 (en) 2005-05-26
JP2007512810A (ja) 2007-05-24
US20050186590A1 (en) 2005-08-25
EP1687406A4 (de) 2008-05-21
EP2163653B1 (de) 2013-03-27
CA2545356A1 (en) 2005-05-26
JP4947355B2 (ja) 2012-06-06
EP2163653A2 (de) 2010-03-17
EP1687406B1 (de) 2010-01-27
WO2005047474A3 (en) 2006-09-14
EP1687406A2 (de) 2006-08-09
AU2004290036B2 (en) 2011-08-04
ATE456678T1 (de) 2010-02-15
WO2005047474A2 (en) 2005-05-26
EP2163653A3 (de) 2010-05-26

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