DE602004020999D1 - Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe - Google Patents

Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe

Info

Publication number
DE602004020999D1
DE602004020999D1 DE602004020999T DE602004020999T DE602004020999D1 DE 602004020999 D1 DE602004020999 D1 DE 602004020999D1 DE 602004020999 T DE602004020999 T DE 602004020999T DE 602004020999 T DE602004020999 T DE 602004020999T DE 602004020999 D1 DE602004020999 D1 DE 602004020999D1
Authority
DE
Germany
Prior art keywords
influencing
dispersing
sample
diseases
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004020999T
Other languages
German (de)
English (en)
Inventor
Matt Ewert
Phil Amuso
Andrew Cannons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of South Florida
University of South Florida St Petersburg
Original Assignee
University of South Florida
University of South Florida St Petersburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/604,779 external-priority patent/US7998699B2/en
Application filed by University of South Florida, University of South Florida St Petersburg filed Critical University of South Florida
Publication of DE602004020999D1 publication Critical patent/DE602004020999D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Sustainable Development (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602004020999T 2003-08-15 2004-08-16 Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe Expired - Lifetime DE602004020999D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/604,779 US7998699B2 (en) 2002-08-15 2003-08-15 Early detection of pathogens in blood
US48189204P 2004-01-14 2004-01-14
PCT/US2004/026606 WO2005021799A2 (en) 2003-08-15 2004-08-16 Materials and methods for capture of pathogens and removal of aurintricarboxylic acid from a sample

Publications (1)

Publication Number Publication Date
DE602004020999D1 true DE602004020999D1 (de) 2009-06-18

Family

ID=34840999

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004020999T Expired - Lifetime DE602004020999D1 (de) 2003-08-15 2004-08-16 Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe

Country Status (13)

Country Link
US (12) US7416843B2 (https=)
EP (3) EP2112232B1 (https=)
JP (2) JP4662932B2 (https=)
AT (2) ATE510931T1 (https=)
AU (2) AU2004269340B2 (https=)
DE (1) DE602004020999D1 (https=)
DK (2) DK2103694T3 (https=)
ES (1) ES2325445T3 (https=)
NO (1) NO20061189L (https=)
PL (2) PL2103694T3 (https=)
PT (2) PT2103694E (https=)
SI (1) SI1654387T1 (https=)
WO (1) WO2005021799A2 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7998699B2 (en) 2002-08-15 2011-08-16 University Of South Florida Early detection of pathogens in blood
JP4662932B2 (ja) 2003-08-15 2011-03-30 ユニバーシティー オブ サウス フロリダ 試料からの病原体の捕獲およびアウリントリカルボン酸除去のための物質および方法
CY1110678T1 (el) * 2003-08-15 2015-06-10 University Of South Florida Υλικα και μεθοδοι για την παγιδευση παθογονων και την απομακρυνση του χρυσινοτρικαρβοξυλικου οξεος απο ενα δειγμα
KR101397386B1 (ko) 2005-12-13 2014-05-26 엑스테라 메디컬 코퍼레이션 혈액으로부터 병원성 미생물, 염증 세포 또는 염증단백질의 체외 제거를 위한 방법
CA2576682A1 (en) 2006-03-08 2007-09-08 Martinrea International Inc. Electrolyte delivery system
US20100015628A1 (en) * 2007-02-28 2010-01-21 Ge Healthcare Bio-Sciences Corp. Ambient temperature stable chemical/biological reagents on membranes or filters
ES2861359T3 (es) 2009-12-01 2021-10-06 Exthera Medical Corp Dispositivo para eliminar citoquinas de la sangre con polisacáridos inmovilizados en superficie
EP2333105A1 (en) 2009-12-08 2011-06-15 Koninklijke Philips Electronics N.V. Selective lysis of cells
US20110225809A1 (en) * 2010-03-17 2011-09-22 Alan Francis Daher Apparatus for removably attaching an item to a surface
DK3067431T3 (da) * 2010-09-15 2019-10-14 Debiopharm Int Sa Indretning omfattende blodkomponenter til at adskille målmolekyler eller partikler fra prøver
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
JP2013055888A (ja) * 2011-09-07 2013-03-28 Toyobo Co Ltd 血液培養サンプルからの迅速かつ簡便な細菌検出
EP2861273B1 (en) 2012-06-13 2017-08-23 ExThera Medical Corporation Use of heparin and carbohydrates to treat cancer
FR3001464B1 (fr) 2013-01-25 2016-02-26 Biomerieux Sa Procede d'isolement specifique d'acides nucleiques d'interet
FR3002452B1 (fr) * 2013-02-28 2016-02-12 Dermaconcept Jmc Composition dermatologique antimicrobienne topique
BR112015032134B1 (pt) 2013-06-24 2022-05-10 Exthera Medical Corporation Método de ligação em ponto de extremidade de uma manose não redutora a um substrato e esfera possuindo uma manose ligada em ponto de extremidade
BR112016009827B1 (pt) * 2013-11-08 2021-10-26 Exthera Medical Corporation Método in vitro para concentrar patógenos infecciosos presentes em uma amostra biológica obtida a partir de um indivíduo sob suspeita de estar infectado com os ditos patógenos, concentrador e kit
EP3134146B1 (en) 2014-04-24 2024-12-25 ExThera Medical Corporation Method for removing bacteria from blood using high flow rate
US10857283B2 (en) 2014-09-22 2020-12-08 Exthera Medical Corporation Wearable hemoperfusion device
CN104749009B (zh) * 2015-03-30 2018-05-04 上海云泽生物科技有限公司 用于免疫分析的免疫抑制剂药物提取试剂
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
WO2017151797A1 (en) 2016-03-02 2017-09-08 Exthera Medical Corporation Method for treating drug intoxication
GB2557654A (en) * 2016-12-14 2018-06-27 Uea Enterprises Ltd Method for nucleic acid depletion
AU2018277094A1 (en) 2017-06-01 2020-01-02 Nantomics, Llc DNA stabilization of RNA
WO2020231830A1 (en) 2019-05-16 2020-11-19 Exthera Medical Corporation Method for modulating endothelial glycocalyx structure
EP4025042A4 (en) * 2019-09-06 2023-06-14 The Trustees of Indiana University NOVEL COMPOSITIONS FOR THE DESTRUCTION OF BIOFILM
MX2023014691A (es) * 2021-06-08 2024-05-29 Dna Genotek Inc Composicion de bajo ph y metodo para estabilizar acidos nucleicos en muestras biologicas.

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1541947A (en) 1922-03-21 1925-06-16 Electric Water Sterilizer & Oz Electrolytic cell
US3130038A (en) 1961-03-13 1964-04-21 Int Minerals & Chem Corp Granular fertilizers
US3245780A (en) 1961-04-13 1966-04-12 Phillip A Hunt Chemical Corp Nickel stripping ammoniacal solution containing a nitro benzene compound
US3378443A (en) 1966-04-05 1968-04-16 American Cyanamid Co Anhydrous liquid suspensions of biologics
US4693972A (en) * 1984-01-16 1987-09-15 Becton, Dickinson And Company Composition and method for rapid detection of microorganisms in clinical samples
US4636524A (en) 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US6027877A (en) 1993-11-04 2000-02-22 Gene Check, Inc. Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification
DE69625658T2 (de) * 1995-09-13 2003-07-17 Seikagaku Kogyo K.K.(Seikagaku Corp.), Tokio/Tokyo Kontaktlinse auf Basis photogehärteter Hyaluronsäure
US6825047B1 (en) 1996-04-03 2004-11-30 Applera Corporation Device and method for multiple analyte detection
US5925552A (en) 1996-04-25 1999-07-20 Medtronic, Inc. Method for attachment of biomolecules to medical devices surfaces
US6103525A (en) * 1996-10-17 2000-08-15 The Regents Of The University Of California Hybridoma cell lines producing monoclonal antibodies that bind to human plasma hyaluronidase
SE9604610D0 (sv) 1996-12-16 1996-12-16 Noviscens Ab Medical composition
US6368871B1 (en) 1997-08-13 2002-04-09 Cepheid Non-planar microstructures for manipulation of fluid samples
JP4196236B2 (ja) * 1998-03-17 2008-12-17 東洋紡績株式会社 核酸増幅用試薬および配列特異的な核酸増幅法
US6091979A (en) 1998-07-07 2000-07-18 Children's Medical Center Corporation Subdural electrode arrays for monitoring cortical electrical activity
US6592814B2 (en) 1998-10-02 2003-07-15 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
US6333194B1 (en) 1999-01-19 2001-12-25 The Children's Hospital Of Philadelphia Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
DE60041255D1 (de) 1999-04-28 2009-02-12 Eidgenoess Tech Hochschule Polyionische beschichtungen für analytische und sensor-vorrichtungen
US7306924B2 (en) 2000-04-17 2007-12-11 Purdue Research Foundation Biosensor and related method
US6632610B2 (en) 2000-10-12 2003-10-14 Gensat S.A. Methods of identification and isolation of polynucleotides containing nucleic acid differences
US7001724B1 (en) * 2000-11-28 2006-02-21 Applera Corporation Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases
US7192445B2 (en) 2000-12-06 2007-03-20 Astra Tech Ab Medical prosthetic devices and implants having improved biocompatibility
DE10108483A1 (de) 2001-02-22 2002-09-05 Bayer Ag Phosphorhaltige Polymere für optischen Signalwandler
WO2003047462A1 (en) 2001-03-12 2003-06-12 Clemson University Polysaccharide-based polmerizable hydrogels
CN100494360C (zh) 2001-03-22 2009-06-03 博奥生物有限公司 细胞分离方法及其应用
WO2003048295A1 (en) 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
US7998699B2 (en) 2002-08-15 2011-08-16 University Of South Florida Early detection of pathogens in blood
US7402279B2 (en) 2002-10-31 2008-07-22 Agilent Technologies, Inc. Device with integrated microfluidic and electronic components
JP4166587B2 (ja) 2003-01-24 2008-10-15 株式会社サキコーポレーション 外観検査装置および体積検査方法
US7476363B2 (en) 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
ES2661168T3 (es) 2003-07-12 2018-03-27 Accelerate Diagnostics, Inc. Biodetección sensible y rápida
JP4662932B2 (ja) 2003-08-15 2011-03-30 ユニバーシティー オブ サウス フロリダ 試料からの病原体の捕獲およびアウリントリカルボン酸除去のための物質および方法

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US8927243B2 (en) 2015-01-06
US20140142047A1 (en) 2014-05-22
US8785176B2 (en) 2014-07-22
US20130122509A1 (en) 2013-05-16
US20130109885A1 (en) 2013-05-02
ES2325445T3 (es) 2009-09-04
US20130130234A1 (en) 2013-05-23
DK1654387T3 (da) 2009-06-22
US8465966B2 (en) 2013-06-18
US20140093944A1 (en) 2014-04-03
US20130288342A1 (en) 2013-10-31
JP2007502618A (ja) 2007-02-15
PT2103694E (pt) 2011-07-26
US20050277130A1 (en) 2005-12-15
PT1654387E (pt) 2009-07-20
NO20061189L (no) 2006-04-26
US8916698B2 (en) 2014-12-23
AU2004269340A1 (en) 2005-03-10
US8815502B2 (en) 2014-08-26
JP2010193901A (ja) 2010-09-09
EP2103694A1 (en) 2009-09-23
JP4662932B2 (ja) 2011-03-30
PL2103694T3 (pl) 2011-10-31
EP1654387B1 (en) 2009-05-06
WO2005021799A3 (en) 2005-08-18
AU2010207760B2 (en) 2012-06-07
US20130115687A1 (en) 2013-05-09
JP5253451B2 (ja) 2013-07-31
US8759479B2 (en) 2014-06-24
EP1654387A2 (en) 2006-05-10
EP2103694B1 (en) 2011-05-25
US20130236920A1 (en) 2013-09-12
PL1654387T3 (pl) 2009-10-30
SI1654387T1 (sl) 2009-10-31
DK2103694T3 (da) 2011-09-12
EP2112232A1 (en) 2009-10-28
ATE510931T1 (de) 2011-06-15
AU2004269340B2 (en) 2010-09-16
AU2010207760A1 (en) 2010-09-02
US8592200B2 (en) 2013-11-26
US20130130302A1 (en) 2013-05-23
US8735090B2 (en) 2014-05-27
US20130130271A1 (en) 2013-05-23
EP2112232B1 (en) 2014-04-23
US7416843B2 (en) 2008-08-26
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