DE602004018270D1 - Nukleinsäureamplifikation mit nichtstandardbasen - Google Patents

Nukleinsäureamplifikation mit nichtstandardbasen

Info

Publication number
DE602004018270D1
DE602004018270D1 DE602004018270T DE602004018270T DE602004018270D1 DE 602004018270 D1 DE602004018270 D1 DE 602004018270D1 DE 602004018270 T DE602004018270 T DE 602004018270T DE 602004018270 T DE602004018270 T DE 602004018270T DE 602004018270 D1 DE602004018270 D1 DE 602004018270D1
Authority
DE
Germany
Prior art keywords
amplification
standard
nucleic acid
standard bases
acid amplification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004018270T
Other languages
German (de)
English (en)
Inventor
James R Prudent
Scott C Johnson
Michael J Moser
David J Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Corp
Original Assignee
Eragen Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eragen Biosciences Inc filed Critical Eragen Biosciences Inc
Publication of DE602004018270D1 publication Critical patent/DE602004018270D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
DE602004018270T 2003-01-17 2004-01-17 Nukleinsäureamplifikation mit nichtstandardbasen Expired - Lifetime DE602004018270D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44092103P 2003-01-17 2003-01-17
PCT/US2004/001397 WO2004065550A2 (en) 2003-01-17 2004-01-17 Nucleic acid amplification using non-standard bases

Publications (1)

Publication Number Publication Date
DE602004018270D1 true DE602004018270D1 (de) 2009-01-22

Family

ID=32771878

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004018270T Expired - Lifetime DE602004018270D1 (de) 2003-01-17 2004-01-17 Nukleinsäureamplifikation mit nichtstandardbasen

Country Status (8)

Country Link
US (1) US7514212B2 (https=)
EP (1) EP1590482B1 (https=)
JP (1) JP4621197B2 (https=)
AT (1) ATE417129T1 (https=)
AU (1) AU2004206246B2 (https=)
CA (1) CA2513626C (https=)
DE (1) DE602004018270D1 (https=)
WO (1) WO2004065550A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006101913A2 (en) * 2005-03-18 2006-09-28 Eragen Biosciences, Inc. Methods for detecting multiple species and subspecies of neiserria
US8293472B2 (en) 2005-06-07 2012-10-23 Luminex Corporation Methods for detection and typing of nucleic acids
US7759062B2 (en) 2006-06-09 2010-07-20 Third Wave Technologies, Inc. T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
AU2009232716B2 (en) * 2008-03-31 2015-02-05 Tagcyx Biotechnologies Novel DNA capable of being amplified by PCR with high selectivity and high efficiency
US10865431B1 (en) * 2008-06-17 2020-12-15 Steven A Benner Polymerase incorporation of non-standard nucleotides
EP2391883B1 (en) 2009-01-30 2018-03-07 Micronics, Inc. Portable high gain fluorescence detection system
WO2011050278A1 (en) * 2009-10-23 2011-04-28 Eragen Biosciences, Inc. Amplification primers with non-standard bases for increased reaction specificity
EP2528687B1 (en) 2010-01-29 2018-08-22 Micronics, Inc. System comprising a host instrument and a microfluidic cartridge for assays
EP3620533B1 (en) 2011-09-06 2023-01-18 Gen-Probe Incorporated Closed nucleic acid structures
EP2753714B1 (en) 2011-09-06 2017-04-12 Gen-Probe Incorporated Circularized templates for sequencing
US20150259571A1 (en) * 2012-08-31 2015-09-17 Empire Technology Development Llc Lignin membranes and coatings
EP3549674B1 (en) 2012-12-21 2020-08-12 PerkinElmer Health Sciences, Inc. Low elasticity films for microfluidic use
CN104919035B (zh) 2012-12-21 2017-08-11 精密公司 便携式荧光检测系统和微测定盒
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
JP6472788B2 (ja) 2013-05-07 2019-02-20 マイクロニクス， インコーポレイテッド 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
JP6484222B2 (ja) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド 核酸の調製および分析のためのデバイス
EP2994750B1 (en) 2013-05-07 2020-08-12 PerkinElmer Health Sciences, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
AU2016257426B2 (en) 2015-05-01 2020-01-16 Gen-Probe Incorporated Multiplex invasive cleavage assays
WO2023043280A1 (ko) * 2021-09-17 2023-03-23 주식회사 씨젠 합성 비자연 염기를 포함하는 태그 올리고뉴클레오타이드를 이용한 타겟 핵산 서열의 검출
EP4610367B1 (en) * 2024-03-01 2026-02-04 Genomill Health Oy Methods for accurate parallel amplification, detection and quantification of nucleic acids

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US5470974A (en) * 1985-03-15 1995-11-28 Neu-Gene Development Group Uncharged polynucleotide-binding polymers
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4996143A (en) * 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
US4800159A (en) * 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US6444798B1 (en) * 1988-06-06 2002-09-03 Steven Albert Benner Chimeras of sulfur-linked oligonucleotide analogs and DNA and RNA
GB8827160D0 (en) 1988-11-21 1988-12-29 Apothekernes Lab Detection & quantitative determination of rna & dna
GB8902689D0 (en) 1989-02-07 1989-03-30 Ici Plc Assay method
US5856092A (en) * 1989-02-13 1999-01-05 Geneco Pty Ltd Detection of a nucleic acid sequence or a change therein
GB8920097D0 (en) 1989-09-06 1989-10-18 Ici Plc Amplification processes
US6007984A (en) * 1989-11-01 1999-12-28 Zeneca Limited Detection of DNA/RNA by fluorescence polarization
US5412088A (en) * 1989-11-20 1995-05-02 Rutgers, The State University 6-O-substituted guanosine derivatives
US5177064A (en) * 1990-07-13 1993-01-05 University Of Florida Targeted drug delivery via phosphonate derivatives
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5965364A (en) * 1990-10-09 1999-10-12 Benner; Steven Albert Method for selecting functional deoxyribonucleotide derivatives
US5432272A (en) * 1990-10-09 1995-07-11 Benner; Steven A. Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
US6140496A (en) * 1990-10-09 2000-10-31 Benner; Steven Albert Precursors for deoxyribonucleotides containing non-standard nucleosides
US6037120A (en) * 1995-10-12 2000-03-14 Benner; Steven Albert Recognition of oligonucleotides containing non-standard base pairs
DK0515660T3 (da) 1990-12-21 1997-07-28 Hoffmann La Roche HLA-DQbeta-DNA-typebestemmelse
DE4129653A1 (de) * 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
US5846717A (en) * 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5958784A (en) * 1992-03-25 1999-09-28 Benner; Steven Albert Predicting folded structures of proteins
WO1994021820A1 (en) 1993-03-17 1994-09-29 City Of Hope Nucleic acid sequences having single stranded ends
US5593836A (en) * 1993-05-14 1997-01-14 Niemiec; John T. Primers and probes for detecting Pneumocystis carinii
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
EP0754240B1 (en) * 1994-02-07 2003-08-20 Beckman Coulter, Inc. Ligase/polymerase-mediated genetic bit analysis of single nucleotide polymorphisms and its use in genetic analysis
US5681702A (en) * 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US5604097A (en) * 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US5763169A (en) * 1995-01-13 1998-06-09 Chiron Diagnostics Corporation Nucleic acid probes for the detection and identification of fungi
GB9507238D0 (en) 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US5705621A (en) * 1995-11-17 1998-01-06 Isis Pharmaceuticals, Inc. Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same
WO1997035033A1 (en) * 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
US5780233A (en) 1996-06-06 1998-07-14 Wisconsin Alumni Research Foundation Artificial mismatch hybridization
US6124092A (en) 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
JP4185185B2 (ja) 1997-05-08 2008-11-26 征夫 軽部 部分二重鎖ｄｎａを利用したｄｎａの検出方法
US5928869A (en) * 1997-05-30 1999-07-27 Becton, Dickinson And Company Detection of nucleic acids by fluorescence quenching
GB9725197D0 (en) * 1997-11-29 1998-01-28 Secr Defence Detection system
CA2331896C (en) * 1998-05-14 2009-09-15 Luminex Corporation Diode laser based measurement apparatus
JP3662850B2 (ja) 1998-06-24 2005-06-22 イルミナ インコーポレイテッド 微小球を有するアレイセンサーのデコード
US6528254B1 (en) * 1999-10-29 2003-03-04 Stratagene Methods for detection of a target nucleic acid sequence
WO2001051669A2 (en) * 2000-01-15 2001-07-19 Genelabs Technologies, Inc. Nucleic acid binding assay and selection method
US6977161B2 (en) * 2000-10-14 2005-12-20 Eragen Biosciences, Inc. Solid support assay systems and methods utilizing non-standard bases
ATE497018T1 (de) * 2000-05-19 2011-02-15 Eragen Biosciences Inc Materialien und methoden zum nachweis von nukleinsäuren
US7374882B2 (en) * 2000-11-28 2008-05-20 Riken Method for base sequencing and biologically active nucleic acids
US20030194705A1 (en) * 2002-03-01 2003-10-16 Schroth Gary P. Methods of using unnatural nucleobases for decoding

Also Published As

Publication number Publication date
EP1590482A2 (en) 2005-11-02
EP1590482B1 (en) 2008-12-10
EP1590482A4 (en) 2006-07-26
AU2004206246A1 (en) 2004-08-05
WO2004065550A3 (en) 2004-12-23
AU2004206246B2 (en) 2009-10-01
WO2004065550A2 (en) 2004-08-05
JP2006515760A (ja) 2006-06-08
ATE417129T1 (de) 2008-12-15
CA2513626A1 (en) 2004-08-05
JP4621197B2 (ja) 2011-01-26
US20070105099A1 (en) 2007-05-10
CA2513626C (en) 2013-03-19
US7514212B2 (en) 2009-04-07

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