DE602004015182D1 - Arznei-eluierender Stent für eine kontrollierte Wirkstoffabgabe - Google Patents

Arznei-eluierender Stent für eine kontrollierte Wirkstoffabgabe

Info

Publication number
DE602004015182D1
DE602004015182D1 DE602004015182T DE602004015182T DE602004015182D1 DE 602004015182 D1 DE602004015182 D1 DE 602004015182D1 DE 602004015182 T DE602004015182 T DE 602004015182T DE 602004015182 T DE602004015182 T DE 602004015182T DE 602004015182 D1 DE602004015182 D1 DE 602004015182D1
Authority
DE
Germany
Prior art keywords
active ingredient
controlled release
drug eluting
eluting stent
stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004015182T
Other languages
English (en)
Inventor
Thomas Q Dinh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Vascular Inc
Original Assignee
Medtronic Vascular Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Vascular Inc filed Critical Medtronic Vascular Inc
Publication of DE602004015182D1 publication Critical patent/DE602004015182D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/022Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541Adjacent bands are arranged out of phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0013Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers
DE602004015182T 2003-04-08 2004-04-08 Arznei-eluierender Stent für eine kontrollierte Wirkstoffabgabe Expired - Lifetime DE602004015182D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/408,920 US7163555B2 (en) 2003-04-08 2003-04-08 Drug-eluting stent for controlled drug delivery

Publications (1)

Publication Number Publication Date
DE602004015182D1 true DE602004015182D1 (de) 2008-09-04

Family

ID=32869184

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004015182T Expired - Lifetime DE602004015182D1 (de) 2003-04-08 2004-04-08 Arznei-eluierender Stent für eine kontrollierte Wirkstoffabgabe

Country Status (4)

Country Link
US (1) US7163555B2 (de)
EP (1) EP1466634B1 (de)
JP (1) JP4617095B2 (de)
DE (1) DE602004015182D1 (de)

Families Citing this family (179)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2178541C (en) * 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
US7341598B2 (en) 1999-01-13 2008-03-11 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US20050283228A1 (en) * 1998-07-29 2005-12-22 Stanford Ulf H Expandable stent with relief holes capable of carrying medicines and other materials
US8382821B2 (en) 1998-12-03 2013-02-26 Medinol Ltd. Helical hybrid stent
US20040267349A1 (en) 2003-06-27 2004-12-30 Kobi Richter Amorphous metal alloy medical devices
EP1132058A1 (de) 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravaskuläre Prothese
US20050271701A1 (en) * 2000-03-15 2005-12-08 Orbus Medical Technologies, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US20160287708A9 (en) * 2000-03-15 2016-10-06 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US9522217B2 (en) * 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) * 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US8460367B2 (en) 2000-03-15 2013-06-11 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9107605B2 (en) * 2000-11-17 2015-08-18 Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. Device for in vivo delivery of bioactive agents and method of manufacture thereof
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
US7163555B2 (en) 2003-04-08 2007-01-16 Medtronic Vascular, Inc. Drug-eluting stent for controlled drug delivery
US20050070996A1 (en) * 2003-04-08 2005-03-31 Dinh Thomas Q. Drug-eluting stent for controlled drug delivery
US7407684B2 (en) * 2004-01-28 2008-08-05 Boston Scientific Scimed, Inc. Multi-step method of manufacturing a medical device
US7349971B2 (en) * 2004-02-05 2008-03-25 Scenera Technologies, Llc System for transmitting data utilizing multiple communication applications simultaneously in response to user request without specifying recipient's communication information
US20050209684A1 (en) * 2004-03-04 2005-09-22 Harold Alexander Surgical stent having micro-geometric patterned surface
US7744644B2 (en) * 2004-03-19 2010-06-29 Boston Scientific Scimed, Inc. Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release
CN1788310B (zh) * 2004-04-27 2010-06-16 柯尼卡美能达精密光学株式会社 物镜及光拾取装置
CA2559540A1 (en) 2004-06-08 2005-12-29 Advanced Stent Technologies, Inc. Stent with protruding branch portion for bifurcated vessels
US20050278929A1 (en) * 2004-06-16 2005-12-22 National Taipei University Technology Process of manufacturing stent with therapeutic function in the human body
US20060009839A1 (en) * 2004-07-12 2006-01-12 Scimed Life Systems, Inc. Composite vascular graft including bioactive agent coating and biodegradable sheath
US7601382B2 (en) * 2004-08-05 2009-10-13 Boston Scientific Scimed, Inc. Method of making a coated medical device
US20060054604A1 (en) * 2004-09-10 2006-03-16 Saunders Richard J Laser process to produce drug delivery channel in metal stents
US7588642B1 (en) * 2004-11-29 2009-09-15 Advanced Cardiovascular Systems, Inc. Abluminal stent coating apparatus and method using a brush assembly
US20060165667A1 (en) * 2004-12-03 2006-07-27 Case Western Reserve University Novel methods, compositions and devices for inducing neovascularization
EP1830900A1 (de) * 2004-12-16 2007-09-12 Miv Therapeutics Inc. Mehrschichtige arzneimittelabgabevorrichtung und herstellungsverfahren dafür
KR100511618B1 (ko) * 2005-01-17 2005-08-31 이경범 약물방출 조절형 다층 코팅 스텐트 및 이의 제조방법
AU2006218782C1 (en) * 2005-02-28 2012-07-05 Cook Medical Technologies Llc Removable coiled stent
US20090087380A1 (en) * 2005-04-11 2009-04-02 Fasching Rainer J Polymer devices for therapeutic applications
US20060275341A1 (en) * 2005-06-02 2006-12-07 Miv Therapeutics Inc. Thin foam coating comprising discrete, closed-cell capsules
JP4927836B2 (ja) * 2005-06-29 2012-05-09 ビピン・シー・パタディア 基端方向に拡がるステントを配備するシステム及び方法
US9101949B2 (en) 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
WO2007021749A1 (en) * 2005-08-10 2007-02-22 Med Institute, Inc. Intraluminal device with a hollow structure
US7896539B2 (en) 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
US20070045252A1 (en) * 2005-08-23 2007-03-01 Klaus Kleine Laser induced plasma machining with a process gas
US20070055352A1 (en) * 2005-09-07 2007-03-08 Wendy Naimark Stent with pockets for containing a therapeutic agent
US20070196423A1 (en) * 2005-11-21 2007-08-23 Med Institute, Inc. Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent
US7540881B2 (en) 2005-12-22 2009-06-02 Boston Scientific Scimed, Inc. Bifurcation stent pattern
US20070156230A1 (en) 2006-01-04 2007-07-05 Dugan Stephen R Stents with radiopaque markers
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070244548A1 (en) * 2006-02-27 2007-10-18 Cook Incorporated Sugar-and drug-coated medical device
US8828077B2 (en) * 2006-03-15 2014-09-09 Medinol Ltd. Flat process of preparing drug eluting stents
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US7729783B2 (en) * 2006-04-26 2010-06-01 Medtronic, Inc. Apparatus and methods for vacuum- and mechanically-assisted fixation of medical electrical leads
US20130325104A1 (en) 2006-05-26 2013-12-05 Abbott Cardiovascular Systems Inc. Stents With Radiopaque Markers
US8535372B1 (en) 2006-06-16 2013-09-17 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with prohealing layer
US8128688B2 (en) * 2006-06-27 2012-03-06 Abbott Cardiovascular Systems Inc. Carbon coating on an implantable device
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
JP2009542359A (ja) 2006-06-29 2009-12-03 ボストン サイエンティフィック リミテッド 選択的被覆部を備えた医療装置
US7823263B2 (en) 2006-07-11 2010-11-02 Abbott Cardiovascular Systems Inc. Method of removing stent islands from a stent
US20080015684A1 (en) 2006-07-11 2008-01-17 Wu Patrick P Method And Apparatus For Attaching Radiopaque Markers To A Stent
US8052743B2 (en) 2006-08-02 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis with three-dimensional disintegration control
JP2010503469A (ja) * 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド 薬物溶出性皮膜を有する医療デバイス
CA2663250A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
ES2357661T3 (es) 2006-09-15 2011-04-28 Boston Scientific Scimed, Inc. Endoprótesis bioerosionables con capas inorgánicas bioestables.
US8057534B2 (en) 2006-09-15 2011-11-15 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
CA2663762A1 (en) 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
US7951191B2 (en) 2006-10-10 2011-05-31 Boston Scientific Scimed, Inc. Bifurcated stent with entire circumferential petal
CN101631513B (zh) * 2006-10-20 2013-06-05 奥巴斯尼茨医学公司 可生物吸收的聚合物组合物和医疗设备
WO2008051867A2 (en) * 2006-10-20 2008-05-02 Elixir Medical Corporation Luminal prostheses and methods for coating thereof
JP2010508878A (ja) * 2006-11-06 2010-03-25 バイオリング ソシエテ アノニム 吸収性尿道内プロテーゼ
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US7842082B2 (en) 2006-11-16 2010-11-30 Boston Scientific Scimed, Inc. Bifurcated stent
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US8414909B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
WO2008074153A1 (en) 2006-12-18 2008-06-26 Electronic Dietary Foods Inc. Device for delivery of a substance
ES2506144T3 (es) 2006-12-28 2014-10-13 Boston Scientific Limited Endoprótesis bioerosionables y procedimiento de fabricación de las mismas
US20080175881A1 (en) * 2007-01-18 2008-07-24 Boston Scientific Scimed, Inc. Blood-contacting medical devices for the release of nitric oxide and anti-restenotic agents
EP2107895A1 (de) * 2007-01-29 2009-10-14 Cook Incorporated Medizinische prothese und herstellungsverfahren
US7575593B2 (en) * 2007-01-30 2009-08-18 Medtronic Vascular, Inc. Implantable device with reservoirs for increased drug loading
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8118861B2 (en) 2007-03-28 2012-02-21 Boston Scientific Scimed, Inc. Bifurcation stent and balloon assemblies
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
JP2008305262A (ja) * 2007-06-08 2008-12-18 Konica Minolta Business Technologies Inc サーバ及びシンクライアント環境でのプリンタ紹介方法
US20100070020A1 (en) 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
US7901452B2 (en) * 2007-06-27 2011-03-08 Abbott Cardiovascular Systems Inc. Method to fabricate a stent having selected morphology to reduce restenosis
US7955381B1 (en) 2007-06-29 2011-06-07 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical device with different types of bioceramic particles
EP2173400B1 (de) * 2007-07-06 2013-11-20 Boston Scientific Scimed, Inc. Implantierbare medizinische vorrichtung mit anpassbarer porengrösse und herstellungsverfahren dafür
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
JP2010533563A (ja) 2007-07-19 2010-10-28 ボストン サイエンティフィック リミテッド 吸着抑制表面を有する内部人工器官
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US8221822B2 (en) 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
EP2185103B1 (de) 2007-08-03 2014-02-12 Boston Scientific Scimed, Inc. Überzug für ein medizinprodukt mit vergrösserter oberfläche
US7959669B2 (en) 2007-09-12 2011-06-14 Boston Scientific Scimed, Inc. Bifurcated stent with open ended side branch support
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090081272A1 (en) * 2007-09-24 2009-03-26 John Clarke Medical devices having a metal particulate composition for controlled diffusion
CN101411651B (zh) * 2007-10-17 2011-03-09 微创医疗器械(上海)有限公司 一种嵌套式结构的人体管腔内支架
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7833266B2 (en) 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
US8388678B2 (en) * 2007-12-12 2013-03-05 Boston Scientific Scimed, Inc. Medical devices having porous component for controlled diffusion
US7722661B2 (en) * 2007-12-19 2010-05-25 Boston Scientific Scimed, Inc. Stent
US8277501B2 (en) 2007-12-21 2012-10-02 Boston Scientific Scimed, Inc. Bi-stable bifurcated stent petal geometry
US8303650B2 (en) 2008-01-10 2012-11-06 Telesis Research, Llc Biodegradable self-expanding drug-eluting prosthesis
US8317857B2 (en) * 2008-01-10 2012-11-27 Telesis Research, Llc Biodegradable self-expanding prosthesis
US20090192583A1 (en) * 2008-01-28 2009-07-30 Medtronic Vascular, Inc. Ordered Coatings for Drug Eluting Stents and Medical Devices
WO2009108716A2 (en) 2008-02-27 2009-09-03 University Of Louisville Research Foundation Synthetic peptides
US8920491B2 (en) 2008-04-22 2014-12-30 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
WO2009135008A2 (en) * 2008-05-01 2009-11-05 Boston Scientific Scimed, Inc. Drug-loaded medical devices and methods for manufacturing drug-loaded medical devices
US8114151B2 (en) * 2008-05-08 2012-02-14 Boston Scientific Scimed, Inc. Stent with tabs and holes for drug delivery
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (de) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprothesen-beschichtung
US20090319026A1 (en) * 2008-06-20 2009-12-24 Boston Scientific Scimed, Inc. Composite Stent with Reservoirs for Drug Delivery and Methods of Manufacturing
DE102008040356A1 (de) 2008-07-11 2010-01-14 Biotronik Vi Patent Ag Stent mit biodegradierbaren Stentstreben und Wirkstoffdepots
US7951193B2 (en) 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
JP2011530347A (ja) * 2008-08-07 2011-12-22 エクソジェネシス コーポレーション 薬物送達システムおよびその薬物送達システムの製造方法
JP5878369B2 (ja) * 2008-08-07 2016-03-08 エクソジェネシス コーポレーション 骨インプラントのための医療機器およびその機器の製造方法
US8642063B2 (en) * 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
WO2010024898A2 (en) 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US20100082096A1 (en) * 2008-09-30 2010-04-01 Boston Scientific Scimed, Inc. Tailored Luminal & Abluminal Drug Elution
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
WO2010048052A1 (en) 2008-10-22 2010-04-29 Boston Scientific Scimed, Inc. Shape memory tubular stent with grooves
CN101732114B (zh) * 2008-11-04 2014-07-30 上海微创医疗器械(集团)有限公司 开有载药槽的冠状动脉血管支架
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
KR101678372B1 (ko) * 2009-02-02 2016-12-06 코디스 코포레이션 가요성 스텐트 디자인
US8872062B2 (en) 2009-02-03 2014-10-28 Abbott Cardiovascular Systems Inc. Laser cutting process for forming stents
US8530783B2 (en) 2009-02-03 2013-09-10 Abbott Cardiovascular Systems Inc. Laser cutting system
EP2393627B1 (de) 2009-02-03 2018-05-09 Abbott Cardiovascular Systems Inc. Mehrfachstrahllasersystem zur herstellung von stents
EP2403546A2 (de) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8758436B2 (en) * 2009-09-17 2014-06-24 Lawrence G. Clayton Ear insert for relief of TMJ discomfort and headaches
US8808353B2 (en) 2010-01-30 2014-08-19 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds having a low crossing profile
US8568471B2 (en) 2010-01-30 2013-10-29 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
JP5668192B2 (ja) * 2010-03-10 2015-02-12 株式会社ライトニックス 医療用針及び穿刺具
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8551159B2 (en) 2010-04-01 2013-10-08 Abbott Cardiovascular Systems Inc. Implantable prosthesis having through-holes
US8562670B2 (en) * 2010-04-01 2013-10-22 Abbott Cardiovascular Systems Inc. Implantable prosthesis with depot retention feature
US8679394B2 (en) 2010-06-10 2014-03-25 Abbott Cardiovascular Systems Inc. Laser system and processing conditions for manufacturing bioabsorbable stents
JP5902165B2 (ja) 2010-08-02 2016-04-13 コーディス・コーポレイションCordis Corporation 異なる螺旋状領域を有する可撓性螺旋状ステント
KR101644410B1 (ko) 2010-08-02 2016-08-01 코디스 코포레이션 중간 구조적 피쳐를 갖는 가요성 나선형 스텐트
BR112013002637B1 (pt) 2010-08-02 2020-12-29 CARDINAL HEALTH SWITZERLAND 515 GmbH stent flexível tendo articulações que se projetam
JP5914479B2 (ja) 2010-08-02 2016-05-11 コーディス・コーポレイションCordis Corporation 非螺旋状中間領域を有する可撓性螺旋状ステント
US8556511B2 (en) 2010-09-08 2013-10-15 Abbott Cardiovascular Systems, Inc. Fluid bearing to support stent tubing during laser cutting
CA2813249A1 (en) 2010-10-01 2012-04-05 University Of Tennessee Research Foundation Multigraft copolymers as superelastomers
US9056025B2 (en) 2010-12-15 2015-06-16 Svelte Medical Systems, Inc. Means and method for preventing embolization of drug eluting stents
US8726483B2 (en) 2011-07-29 2014-05-20 Abbott Cardiovascular Systems Inc. Methods for uniform crimping and deployment of a polymer scaffold
DE102012208615A1 (de) 2012-05-23 2013-11-28 Universität Rostock Wirkstoff freisetzendes Implantat und Verfahren und Vorrichtung zur seiner Herstellung
WO2014186435A2 (en) 2013-05-14 2014-11-20 University Of Georgia Research Foundation, Inc. Compositions and methods for reducing neointima formation
TWI510226B (zh) * 2013-09-11 2015-12-01 Univ Nat Taiwan 微型儲藥槽血管支架
CN106456771B9 (zh) 2014-05-02 2021-07-20 国家儿童医院研究所 用于抗lyst免疫调节的组合物和方法
WO2015196093A1 (en) 2014-06-20 2015-12-23 University Of Tennessee Research Foundation Multigraft copolymer superelastomers by emulsion polymerization
US9579427B2 (en) * 2014-06-28 2017-02-28 Cordis Corporation Thin-film composite retrievable endovascular devices and method of use
US9999527B2 (en) 2015-02-11 2018-06-19 Abbott Cardiovascular Systems Inc. Scaffolds having radiopaque markers
US9737368B2 (en) 2015-02-24 2017-08-22 Abbott Cardiovascular Systems Inc. System and method for attaching a radiopaque marker bead to an endoprosthesis
JP7064880B2 (ja) 2015-04-01 2022-05-11 イェール ユニバーシティー 医療用インプラント上の生物製剤の付着のための鉄白金粒子
US9700443B2 (en) 2015-06-12 2017-07-11 Abbott Cardiovascular Systems Inc. Methods for attaching a radiopaque marker to a scaffold
US11541149B2 (en) 2015-12-11 2023-01-03 Research Institute At Nationwide Children's Hospital Systems and methods for optimized patient specific tissue engineering vascular grafts
US10065018B2 (en) 2016-03-16 2018-09-04 Krishna Rocha-Singh Apparatus and method for promoting angiogenesis in ischemic tissue
US10610669B2 (en) 2016-03-16 2020-04-07 Krishna Rocha-Singh, M.D. Apparatus and method for promoting angiogenesis in ischemic tissue
US11325991B2 (en) 2017-04-25 2022-05-10 University Of Tennessee Research Foundation All-acrylic multigraft copolymer superelastomers
EP4021369A4 (de) * 2019-08-26 2023-12-27 Mervyn B. Forman Medizinische vorrichtungen zur kontinuierlichen abgabe therapeutischer mittel
US11638654B2 (en) 2019-11-21 2023-05-02 Cook Medical Technologies Llc Detachable and retrievable stents for therapeutic agent delivery
CN214712943U (zh) * 2020-09-30 2021-11-16 普利瑞医疗科技(苏州)有限公司 一种医用药物支架

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US27340A (en) 1860-03-06 Improvement in steam-boilers
US7209A (en) 1850-03-26 Method of connecting the sections oe gold-washers
US5891108A (en) 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
US5769884A (en) * 1996-06-27 1998-06-23 Cordis Corporation Controlled porosity endovascular implant
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5843172A (en) * 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US7208010B2 (en) * 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
EP1174157B1 (de) * 1998-04-27 2005-06-29 Surmodics Inc. Bioaktive Wirkstoffe freisetzende Beschichtungen
EP2292190B1 (de) 2000-10-16 2017-11-08 Conor Medsystems, Inc. Expandierbare medizinische Vorrichtung zur Freisetzung eines Heilmittels
US6758859B1 (en) * 2000-10-30 2004-07-06 Kenny L. Dang Increased drug-loading and reduced stress drug delivery device
US6517888B1 (en) 2000-11-28 2003-02-11 Scimed Life Systems, Inc. Method for manufacturing a medical device having a coated portion by laser ablation
US7163555B2 (en) 2003-04-08 2007-01-16 Medtronic Vascular, Inc. Drug-eluting stent for controlled drug delivery

Also Published As

Publication number Publication date
US20040204750A1 (en) 2004-10-14
JP2004305753A (ja) 2004-11-04
US7163555B2 (en) 2007-01-16
EP1466634A1 (de) 2004-10-13
JP4617095B2 (ja) 2011-01-19
EP1466634B1 (de) 2008-07-23

Similar Documents

Publication Publication Date Title
DE602004015182D1 (de) Arznei-eluierender Stent für eine kontrollierte Wirkstoffabgabe
DE602005026984D1 (de) Chinolin-derivate zur behandlung von latenter tuberkulose
IS8398A (is) Lyfjasamsetningar til að meðhöndla æxli
DK1478339T3 (da) Farmaceutiske formuleringer af antineoplastiske midler, specielt temozolomid, fremgangsmåder til fremstilling og anvendelse heraf
NO20054244D0 (no) Nitrogeninneholdende heterocykliske derivater og legemidler inneholdende de samme som den aktive bestanddel
DE602004012816D1 (de) Selbstexpandierbarer Stent und Stenteinbringungssystem zur Behandlung von Gefässerkrankungen
NO20043702L (no) 8-azaprostaglandinderivatforbindelser og legemidler inneholdende forbindelsene som den aktive bestanddel
CY2013023I2 (el) Φαρμακο για την υπερδραστηρια ουροδοχο κυστη περιλαμβανον παραγωγο ανιλιδιου οξικου οξεοσως το ενεργο συστατικο
BRPI0607198A2 (pt) composição, uso da composição método de tratamento doenças, e, embalagem farmacêutica
BRPI0717442A2 (pt) Stent endovascular para liberação de droga e método de uso
DK1853271T3 (da) Fremgangsmåde og præparat til behandling af perifere vaskulære sygdomme
IL181783A0 (en) Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient
IL195269A0 (en) Pharmaceutical formulations for the sustained release of active ingredient(s), as well as their applications, especially therapeutic
DK1498411T3 (da) Diketohydrazinderivatforbindelser og medikamenter indeholdende forbindelserne som den aktive bestanddel
IS7298A (is) Platínuafleiða lyfjasamsetningar
DK1817282T3 (da) Til behandling af respiratoriske sygdomme egnede phenoxy derivater
IL183252A0 (en) Solid formulations of liquid biologically active agents
ATE408664T1 (de) Abgabesystem für wirkstoff
BRPI0717438A2 (pt) Stent endovascular para liberação de droga e método de uso
DK2422786T3 (da) Nye lægemiddelkombinationer til behandling af luftvejssygdomme
IL180031A0 (en) Stable pharmaceutical formulations of benzimidazole compounds
EP1932522A4 (de) Therapeutisches mittel gegen lebererkrankungen mit einem 2-amino-1,3-propandiol-derivat als wirkstoff und therapeutisches verfahren gegen lebererkrankungen
DE602005023127D1 (de) Künstliche physiologische salzlösung und verfahren zu ihrer herstellung
CY2018006I1 (el) Θεραπευτικο σχημα κλαδριβινης για την θεραπευτικη αντιμετωπιση της σκληρυνσης κατα πλακας
IS8050A (is) Æðaígræði

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803