DE602004002943D1 - Ph-abhängige polypeptidaggregation und verwendung davon - Google Patents
Ph-abhängige polypeptidaggregation und verwendung davonInfo
- Publication number
- DE602004002943D1 DE602004002943D1 DE602004002943T DE602004002943T DE602004002943D1 DE 602004002943 D1 DE602004002943 D1 DE 602004002943D1 DE 602004002943 T DE602004002943 T DE 602004002943T DE 602004002943 T DE602004002943 T DE 602004002943T DE 602004002943 D1 DE602004002943 D1 DE 602004002943D1
- Authority
- DE
- Germany
- Prior art keywords
- aggregation
- proteins
- dissociation
- reversible
- oligomerization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001419 dependent effect Effects 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 8
- 230000002776 aggregation Effects 0.000 abstract 5
- 238000004220 aggregation Methods 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 238000010494 dissociation reaction Methods 0.000 abstract 3
- 230000005593 dissociations Effects 0.000 abstract 3
- 238000006384 oligomerization reaction Methods 0.000 abstract 3
- 230000002441 reversible effect Effects 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 102000029797 Prion Human genes 0.000 abstract 1
- 108091000054 Prion Proteins 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Psychology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US397059 | 2003-03-25 | ||
| US10/397,059 US20040192887A1 (en) | 2003-03-25 | 2003-03-25 | PH-dependent polypeptide aggregation and its use |
| PCT/EP2004/003060 WO2004085464A2 (en) | 2003-03-25 | 2004-03-23 | Ph-dependent polypeptide aggregation and its use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004002943D1 true DE602004002943D1 (de) | 2006-12-07 |
| DE602004002943T2 DE602004002943T2 (de) | 2007-07-05 |
Family
ID=32988937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004002943T Expired - Lifetime DE602004002943T2 (de) | 2003-03-25 | 2004-03-23 | Ph-abhängige polypeptidaggregation und deren verwendung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040192887A1 (de) |
| EP (1) | EP1606628B1 (de) |
| JP (1) | JP4354956B2 (de) |
| CN (1) | CN100595209C (de) |
| AT (1) | ATE343794T1 (de) |
| AU (1) | AU2004224157B2 (de) |
| CA (1) | CA2519993C (de) |
| DE (1) | DE602004002943T2 (de) |
| ES (1) | ES2274439T3 (de) |
| NZ (1) | NZ543111A (de) |
| WO (1) | WO2004085464A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2267496C2 (ru) * | 2004-01-15 | 2006-01-10 | Сергей Иванович Черныш | Противоопухолевые и антивирусные пептиды |
| CA2627621A1 (en) * | 2005-10-28 | 2007-05-03 | Alicon Ag | Method for concentrating, purifying and removing prion protein |
| EA009555B1 (ru) * | 2005-11-30 | 2008-02-28 | Сергей Иванович Черныш | Пептид, обладающий иммуномодулирующей активностью, и фармацевтическая композиция |
| JPWO2011096440A1 (ja) * | 2010-02-03 | 2013-06-10 | 株式会社 ＰＲＩＳＭ ＢｉｏＬａｂ | 天然変性タンパク質に結合する化合物およびそのスクリーニング方法 |
| CN111171115B (zh) * | 2020-01-06 | 2022-05-27 | 山东大学 | 一种通过调节酸碱度控制多肽晶体可逆组装的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164295A (en) * | 1991-03-06 | 1992-11-17 | The Upjohn Company | Method for identifying amyloid protein-extracellular matrix protein affinity altering compounds |
| DK0616613T3 (da) * | 1991-12-03 | 1999-09-27 | Proteus Molecular Design | Fragmenter af prionprotein |
| US5521158A (en) * | 1992-10-08 | 1996-05-28 | Scios Nova Inc. | Pseudopeptide bradykinin receptor antagonists |
| US5891641A (en) * | 1997-02-21 | 1999-04-06 | The Regents Of The University Of California | Assay for disease related conformation of a protein |
| FR2801106B1 (fr) * | 1999-11-12 | 2007-10-05 | Commissariat Energie Atomique | Procede de diagnostic d'une esst provoquee par une souche d'atnc dans un echantillon biologique et son utilisation dans le diagnostic differentiel des differentes souches d'atnc |
| CA2405568A1 (en) * | 2000-04-05 | 2001-10-18 | North Carolina State University | Prion-binding peptidic ligands and methods of using same |
| WO2003000853A2 (en) * | 2001-06-20 | 2003-01-03 | Caprion Pharmaceuticals Inc. | Protein aggregation assays and uses thereof |
-
2003
- 2003-03-25 US US10/397,059 patent/US20040192887A1/en not_active Abandoned
-
2004
- 2004-03-23 NZ NZ543111A patent/NZ543111A/en not_active IP Right Cessation
- 2004-03-23 EP EP04722562A patent/EP1606628B1/de not_active Expired - Lifetime
- 2004-03-23 ES ES04722562T patent/ES2274439T3/es not_active Expired - Lifetime
- 2004-03-23 AT AT04722562T patent/ATE343794T1/de not_active IP Right Cessation
- 2004-03-23 DE DE602004002943T patent/DE602004002943T2/de not_active Expired - Lifetime
- 2004-03-23 CA CA2519993A patent/CA2519993C/en not_active Expired - Fee Related
- 2004-03-23 AU AU2004224157A patent/AU2004224157B2/en not_active Ceased
- 2004-03-23 CN CN200480007849A patent/CN100595209C/zh not_active Expired - Fee Related
- 2004-03-23 WO PCT/EP2004/003060 patent/WO2004085464A2/en active IP Right Grant
- 2004-03-23 JP JP2005518681A patent/JP4354956B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN100595209C (zh) | 2010-03-24 |
| CA2519993C (en) | 2011-02-15 |
| EP1606628A2 (de) | 2005-12-21 |
| AU2004224157A1 (en) | 2004-10-07 |
| WO2004085464A2 (en) | 2004-10-07 |
| US20040192887A1 (en) | 2004-09-30 |
| EP1606628B1 (de) | 2006-10-25 |
| CN1764840A (zh) | 2006-04-26 |
| NZ543111A (en) | 2007-03-30 |
| ES2274439T3 (es) | 2007-05-16 |
| JP4354956B2 (ja) | 2009-10-28 |
| DE602004002943T2 (de) | 2007-07-05 |
| ATE343794T1 (de) | 2006-11-15 |
| JP2007523831A (ja) | 2007-08-23 |
| WO2004085464A3 (en) | 2004-11-11 |
| CA2519993A1 (en) | 2004-10-07 |
| AU2004224157B2 (en) | 2007-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |