DE602004002584D1 - Verwendung von 7-nitro-2,1,3-benzoxadiazol derivaten zur behandlung von krebserkrankungen - Google Patents
Verwendung von 7-nitro-2,1,3-benzoxadiazol derivaten zur behandlung von krebserkrankungenInfo
- Publication number
- DE602004002584D1 DE602004002584D1 DE602004002584T DE602004002584T DE602004002584D1 DE 602004002584 D1 DE602004002584 D1 DE 602004002584D1 DE 602004002584 T DE602004002584 T DE 602004002584T DE 602004002584 T DE602004002584 T DE 602004002584T DE 602004002584 D1 DE602004002584 D1 DE 602004002584D1
- Authority
- DE
- Germany
- Prior art keywords
- nitro
- derivatives
- benzoxadiazol
- treatment
- cancer disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ZCVAGTPWBAZXAL-UHFFFAOYSA-N 4-nitro-2,1,3-benzoxadiazole Chemical class [O-][N+](=O)C1=CC=CC2=NON=C12 ZCVAGTPWBAZXAL-UHFFFAOYSA-N 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 102000005720 Glutathione transferase Human genes 0.000 abstract 2
- 108010070675 Glutathione transferase Proteins 0.000 abstract 2
- 238000011319 anticancer therapy Methods 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM20030194 | 2003-04-24 | ||
| IT000194A ITRM20030194A1 (it) | 2003-04-24 | 2003-04-24 | Uso di derivati del 7-nitro-2, 1, 3-benzossadiazolo per |
| PCT/IT2004/000223 WO2004093874A1 (en) | 2003-04-24 | 2004-04-19 | Use of 7-nitro-2,1,3 benzoxadiazole derivatives for anticancer therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004002584D1 true DE602004002584D1 (de) | 2006-11-09 |
| DE602004002584T2 DE602004002584T2 (de) | 2007-10-25 |
Family
ID=29765779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004002584T Expired - Lifetime DE602004002584T2 (de) | 2003-04-24 | 2004-04-19 | Verwendung von 7-nitro-2,1,3-benzoxadiazol-derivaten zur behandlung von krebserkrankungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8796317B2 (de) |
| EP (1) | EP1615638B1 (de) |
| AT (1) | ATE340573T1 (de) |
| DE (1) | DE602004002584T2 (de) |
| DK (1) | DK1615638T3 (de) |
| ES (1) | ES2274449T3 (de) |
| IT (1) | ITRM20030194A1 (de) |
| PL (1) | PL1615638T3 (de) |
| PT (1) | PT1615638E (de) |
| SI (1) | SI1615638T1 (de) |
| WO (1) | WO2004093874A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2304112B1 (es) * | 2007-02-23 | 2009-08-13 | Universidad De Zaragoza | Uso de compuestos como inhibidores de la flavodoxina de helicobacter. |
| ES2304220B1 (es) * | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas. |
| ES2304221B1 (es) * | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas causadas por helicobacter. |
| WO2008124838A1 (en) * | 2007-04-10 | 2008-10-16 | University Of Maryland, Baltimore | Compounds that inhibit human dna ligases and methods of treating cancer |
| FR2919287B1 (fr) * | 2007-07-26 | 2012-10-12 | Pf Medicament | Nouveaux derives fluorescents de polyamines, leur procede de preparation et leurs applications en tant qu'outils de diagnostic dans le traitement des tumeurs cancereuses. |
| GB0717982D0 (en) * | 2007-09-14 | 2007-10-24 | Univ Durham | Method and means relating to multiple herbicide resistance in plants |
| ITRM20120178A1 (it) * | 2012-04-24 | 2013-10-25 | Uni Degli Studi G D Annun Zio Di Chieti | Derivati del 7-nitro-2,1,3-benzossadiazolo per terapia antitumorale |
| WO2016080853A1 (en) | 2014-11-21 | 2016-05-26 | Bsim2 – Biomolecular Simulations Lda | 2-thioxothiazolidin-4-one derivatives active as transthyretin ligands and uses thereof |
| US10377729B2 (en) | 2015-06-15 | 2019-08-13 | Bsim Therapeutics, S.A. | Bis-furan derivatives as transthyretin (TTR) stabilizers and amyloid inhibitors for the treatment of familial amyloid polyneuropathy (FAP) |
| CN109553590B (zh) * | 2018-11-22 | 2022-04-26 | 东南大学 | 具有谷胱甘肽巯基转移酶抑制功能的化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10045599B4 (de) * | 2000-09-15 | 2004-06-03 | Wella Ag | Haarfärbemittel auf der Basis von 4-Nitro-2,1,3-benzoxadiazol-Derivaten und dessen Verwendung als Farbstoff zum Färben von Haaren |
-
2003
- 2003-04-24 IT IT000194A patent/ITRM20030194A1/it unknown
-
2004
- 2004-04-19 AT AT04728231T patent/ATE340573T1/de not_active IP Right Cessation
- 2004-04-19 PT PT47282314T patent/PT1615638E/pt unknown
- 2004-04-19 DE DE602004002584T patent/DE602004002584T2/de not_active Expired - Lifetime
- 2004-04-19 PL PL04728231T patent/PL1615638T3/pl unknown
- 2004-04-19 DK DK04728231T patent/DK1615638T3/da active
- 2004-04-19 US US10/554,423 patent/US8796317B2/en not_active Expired - Fee Related
- 2004-04-19 WO PCT/IT2004/000223 patent/WO2004093874A1/en active IP Right Grant
- 2004-04-19 ES ES04728231T patent/ES2274449T3/es not_active Expired - Lifetime
- 2004-04-19 SI SI200430110T patent/SI1615638T1/sl unknown
- 2004-04-19 EP EP04728231A patent/EP1615638B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2274449T3 (es) | 2007-05-16 |
| PT1615638E (pt) | 2007-01-31 |
| SI1615638T1 (sl) | 2007-02-28 |
| ITRM20030194A1 (it) | 2004-10-25 |
| DE602004002584T2 (de) | 2007-10-25 |
| ATE340573T1 (de) | 2006-10-15 |
| EP1615638A1 (de) | 2006-01-18 |
| EP1615638B1 (de) | 2006-09-27 |
| ITRM20030194A0 (it) | 2003-04-24 |
| WO2004093874A1 (en) | 2004-11-04 |
| PL1615638T3 (pl) | 2007-01-31 |
| US20060247284A1 (en) | 2006-11-02 |
| US8796317B2 (en) | 2014-08-05 |
| DK1615638T3 (da) | 2007-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de | ||
| 8370 | Indication related to discontinuation of the patent is to be deleted | ||
| 8364 | No opposition during term of opposition |