DE60144399D1 - Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen - Google Patents

Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen

Info

Publication number
DE60144399D1
DE60144399D1 DE60144399T DE60144399T DE60144399D1 DE 60144399 D1 DE60144399 D1 DE 60144399D1 DE 60144399 T DE60144399 T DE 60144399T DE 60144399 T DE60144399 T DE 60144399T DE 60144399 D1 DE60144399 D1 DE 60144399D1
Authority
DE
Germany
Prior art keywords
immunogenicity
proteins
determining
result
immune response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60144399T
Other languages
English (en)
Inventor
David A Estell
Fiona A Harding
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco US Inc
Original Assignee
Danisco US Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/677,822 external-priority patent/US6936249B1/en
Application filed by Danisco US Inc filed Critical Danisco US Inc
Application granted granted Critical
Publication of DE60144399D1 publication Critical patent/DE60144399D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60144399T 2000-10-02 2001-09-26 Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen Expired - Lifetime DE60144399D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/677,822 US6936249B1 (en) 1998-04-15 2000-10-02 Proteins producing an altered immunogenic response and methods of making and using the same
US09/768,080 US6897049B1 (en) 1998-04-15 2001-01-23 Proteins producing an altered immunogenic response and methods of making and using the same
PCT/US2001/030062 WO2002040997A2 (en) 2000-10-02 2001-09-26 Production and use of proteins producing an altered immunogenic response

Publications (1)

Publication Number Publication Date
DE60144399D1 true DE60144399D1 (de) 2011-05-19

Family

ID=27101907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60144399T Expired - Lifetime DE60144399D1 (de) 2000-10-02 2001-09-26 Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen

Country Status (7)

Country Link
EP (1) EP1469721B1 (de)
JP (1) JP5126761B2 (de)
AT (1) ATE504205T1 (de)
AU (1) AU2002237646A1 (de)
CA (1) CA2424720C (de)
DE (1) DE60144399D1 (de)
WO (1) WO2002040997A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2441595C (en) 2001-03-23 2012-07-03 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
DE60304040T2 (de) * 2002-06-11 2006-09-28 Merck Patent Gmbh Methode zur identifizierung und eliminierung von t-zell epitopen
EP1740952A2 (de) * 2004-04-26 2007-01-10 Genencor International, Inc. Populationsbasierte verfahren zur vorhersage für immunantwortbestimmungen und verfahren zur überprüfung der immunologischen antwortdaten
CN102209778B (zh) * 2008-11-11 2014-10-15 丹尼斯科美国公司 包含丝氨酸蛋白酶变体的组合物和方法
CN102064161B (zh) * 2010-11-12 2013-09-04 嘉兴斯达微电子有限公司 一种优化的智能功率模块的功率封装结构
GB2499180A (en) * 2011-09-08 2013-08-14 Alcyomics Ltd Method of identifying sensitizers or allergens using measurements of T-cell proliferation and/or IFN Gamma
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
SG30639G (en) 1986-04-30 1995-09-01 Genencor Int Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors
US5470560A (en) * 1987-01-20 1995-11-28 Genentech, Inc. Method for evaluating immunogenicity
CA2331936C (en) * 1990-12-05 2007-07-31 Novozymes A/S Proteins with changed epitopes and methods for the production thereof
AU8595298A (en) * 1997-07-29 1999-02-22 The Administrators Of The Tulane Eductional Fund Prediction, detection, and design of t cell epitopes
US6642011B2 (en) * 1998-04-15 2003-11-04 Genencor International, Inc. Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
EP1051432B1 (de) * 1998-12-08 2007-01-24 Biovation Limited Verfahren zur verminderung der immunogenität von proteinen

Also Published As

Publication number Publication date
CA2424720A1 (en) 2002-05-23
JP2004528013A (ja) 2004-09-16
WO2002040997A2 (en) 2002-05-23
WO2002040997A3 (en) 2004-08-12
EP1469721A2 (de) 2004-10-27
CA2424720C (en) 2012-04-03
AU2002237646A1 (en) 2002-05-27
ATE504205T1 (de) 2011-04-15
WO2002040997A9 (en) 2002-07-25
EP1469721B1 (de) 2011-04-06
JP5126761B2 (ja) 2013-01-23

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