DE60144015D1 - Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen - Google Patents

Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen

Info

Publication number
DE60144015D1
DE60144015D1 DE60144015T DE60144015T DE60144015D1 DE 60144015 D1 DE60144015 D1 DE 60144015D1 DE 60144015 T DE60144015 T DE 60144015T DE 60144015 T DE60144015 T DE 60144015T DE 60144015 D1 DE60144015 D1 DE 60144015D1
Authority
DE
Germany
Prior art keywords
cell specific
cells
modified embryonic
embryonal
stem cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60144015T
Other languages
English (en)
Inventor
Herve Acloque
Anne-Marie Birot
Valerie Risson
Bertrand Pain
Jacques Samarut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
Ecole Normale Superieure de Lyon
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
Ecole Normale Superieure de Lyon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Recherche Agronomique INRA, Ecole Normale Superieure de Lyon filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE60144015D1 publication Critical patent/DE60144015D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60144015T 2000-05-11 2001-04-19 Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen Expired - Lifetime DE60144015D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0006029A FR2808803B1 (fr) 2000-05-11 2000-05-11 Cellules es modifiees et gene specifique de cellules es
PCT/FR2001/001207 WO2001085938A1 (fr) 2000-05-11 2001-04-19 Cellules es modifiees et gene specifique de cellules es

Publications (1)

Publication Number Publication Date
DE60144015D1 true DE60144015D1 (de) 2011-03-24

Family

ID=8850125

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60144015T Expired - Lifetime DE60144015D1 (de) 2000-05-11 2001-04-19 Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen

Country Status (14)

Country Link
US (2) US20040072169A1 (de)
EP (1) EP1280898B1 (de)
JP (1) JP2004515212A (de)
AT (1) ATE498011T1 (de)
AU (2) AU5488501A (de)
BR (1) BR0110764A (de)
CA (1) CA2408732A1 (de)
DE (1) DE60144015D1 (de)
DK (1) DK1280898T3 (de)
ES (1) ES2358731T3 (de)
FR (1) FR2808803B1 (de)
NO (1) NO331814B1 (de)
NZ (1) NZ522547A (de)
WO (1) WO2001085938A1 (de)

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FR2808803B1 (fr) * 2000-05-11 2004-12-10 Agronomique Inst Nat Rech Cellules es modifiees et gene specifique de cellules es
AU2002306374B2 (en) * 2001-05-31 2008-01-24 Dainippon Sumitomo Pharma Co., Ltd. Genes with ES cell-specific expression
NZ567817A (en) 2005-11-01 2012-01-12 Novartis Vaccines & Diagnostic Cell-derived viral vaccines with low levels of residual cell DNA by beta-propiolactone treatment
WO2007052061A2 (en) 2005-11-04 2007-05-10 Novartis Vaccines And Diagnostics Srl Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines
US20090304742A1 (en) 2005-11-04 2009-12-10 Novartis Vaccines And Diagnostics Srl Influenza vaccines with reduced amount of emulsion adjuvant
CN102727885A (zh) 2005-11-04 2012-10-17 诺华疫苗和诊断有限公司 包含颗粒佐剂和免疫增强剂组合的流感疫苗
DK2368572T3 (da) 2005-11-04 2020-05-25 Seqirus Uk Ltd Adjuvansvacciner med ikke-virionantigener fremstillet fra influenza-virusser dyrket i cellekultur
JP2009514839A (ja) 2005-11-04 2009-04-09 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル サイトカイン誘導剤を含むアジュバントインフルエンザワクチン
WO2007085969A2 (en) 2006-01-27 2007-08-02 Novartis Vaccines And Diagnostics Gmbh & Co Kg Influenza vaccines containing hemagglutinin and matrix proteins
JP2009534303A (ja) 2006-03-24 2009-09-24 ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー 冷蔵しないインフルエンザワクチンの保存
FR2898909A1 (fr) 2006-03-24 2007-09-28 Agronomique Inst Nat Rech Combinaison de marqueurs de cellules aviaires
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
NZ577405A (en) 2006-12-06 2012-08-31 Novartis Ag Vaccines including antigen from four strains of influenza virus
CA2692200A1 (en) 2007-06-27 2008-12-31 Novartis Ag Low-additive influenza vaccines
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
EP2889042A3 (de) 2008-03-18 2015-10-14 Novartis AG Verbesserungen bei der Herstellung von Influenzavirusimpfstoffantigenen
WO2010079081A1 (en) 2009-01-07 2010-07-15 Glaxosmithkline Biologicals S.A. Methods for recovering a virus or a viral antigen produced by cell culture
EP2393922A1 (de) 2009-02-06 2011-12-14 GlaxoSmithKline Biologicals S.A. Aufreinigung von virus oder viralen antigenen mittels dichtegradienten-ultrazentrifugation
PL2396032T3 (pl) 2009-02-10 2017-05-31 Seqirus UK Limited Szczepionki przeciw grypie o obniżonych zawartościach skwalenu
EP2942062A1 (de) 2009-02-10 2015-11-11 Novartis AG Influenza-impfstoff-schemata für pandemie-assoziierte stämme
US20120093860A1 (en) 2009-02-10 2012-04-19 Novartis Ag Influenza vaccines with increased amounts of h3 antigen
USH2284H1 (en) 2009-04-27 2013-09-03 Novartis Ag Vaccines for protecting against influenza
SG178904A1 (en) 2009-09-10 2012-04-27 Novartis Ag Combination vaccines against respiratory tract diseases
US20120309056A1 (en) 2010-02-04 2012-12-06 Leon Arnaud Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
EP2545172B2 (de) 2010-03-08 2017-12-06 Novartis AG Methode zum testen von intrazellulären pathogenen
ES2562818T3 (es) 2010-05-03 2016-03-08 Glaxosmithkline Biologicals S.A. Procedimiento de inactivación del virus de la gripe
JP6072677B2 (ja) 2010-05-06 2017-02-01 ノバルティス アーゲー 微生物の不活化のための有機ペルオキシド化合物
CN103025350A (zh) 2010-05-21 2013-04-03 诺华有限公司 流感病毒的重配方法
PL2575873T3 (pl) 2010-06-01 2016-06-30 Novartis Ag Zatężanie i liofilizacja antygenów szczepionkowych grypy
CA2801149A1 (en) 2010-06-01 2011-12-08 Novartis Ag Concentration of vaccine antigens without lyophilization
CA2808965C (en) 2010-08-20 2020-01-07 Novartis Ag Soluble needle arrays for delivery of influenza vaccines
WO2013000982A1 (en) 2011-06-27 2013-01-03 Vivalis Method for screening cells
GB201216121D0 (en) 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
CA2852857A1 (en) 2011-10-20 2013-04-25 Novartis Ag Adjuvanted influenza b virus vaccines for pediatric priming
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
ES2778928T3 (es) 2013-08-30 2020-08-12 Glaxosmithkline Biologicals Sa Producción a gran escala de virus en cultivos celulares
BE1023903B1 (fr) 2014-12-16 2017-09-08 Glaxosmithkline Biologicals Sa Nouveau procédé
JP6956635B2 (ja) 2014-12-17 2021-11-02 フンダシオン パラ ラ インベスティガシオン メディカ アプリカダ ウィルソン病及び他の状態の処置に使用するための核酸構築物及び遺伝子治療ベクター
KR102526616B1 (ko) 2014-12-17 2023-04-27 푼다시온 파라 라 인베스티가시온 메디카 아플리카다 윌슨병 및 기타 병태의 치료에 사용되기 위한 핵산 구조물 및 유전자 치료용 벡터
JP2018524323A (ja) 2015-06-26 2018-08-30 セキラス ユーケー リミテッド 抗原がマッチしたインフルエンザワクチン
US10416171B2 (en) 2015-07-07 2019-09-17 Seqirus UK Limited Influenza potency assays
WO2019219649A1 (en) 2018-05-14 2019-11-21 Vivet Therapeutics Gene therapy vectors comprising s/mar sequences
KR20210086638A (ko) 2018-10-12 2021-07-08 비베트 테라퓨틱스 진행성 가족성 간내 담즙정체 3형 (pfic3)의 치료를 위한 코돈-최적화 전이유전자
TW202039854A (zh) 2018-11-16 2020-11-01 美商編碼製藥公司 治療威爾遜氏病的組合物和方法
AU2020299718A1 (en) 2019-07-02 2022-02-24 Fundacion Para La Investigacion Medica Aplicada cPLA2e inducing agents and uses thereof
MX2022006005A (es) 2019-11-18 2022-10-27 Seqirus Pty Ltd Metodo para producir virus de la influenza reagrupados.
EP4192961A2 (de) 2020-08-06 2023-06-14 Fundacion para la Investigacion Medica Aplicada Virale partikel zur verwendung bei der behandlung von tauopathien wie morbus alzheimer durch gentherapie
US20230265456A1 (en) 2020-08-10 2023-08-24 Fundacion Para La Investigacion Medica Aplicada Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis
EP4225782A1 (de) 2020-10-09 2023-08-16 UCB Biopharma SRL Nukleinsäurekonstrukte, virale vektoren und virale partikel
CA3234666A1 (en) 2021-10-28 2023-05-04 UCB Biopharma SRL Nucleic acid constructs, viral vectors and viral particles

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US6309822B1 (en) * 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
WO2000012683A2 (en) * 1998-08-31 2000-03-09 New York University Stem cells bearing an fgf receptor on the cell surface
FR2808803B1 (fr) * 2000-05-11 2004-12-10 Agronomique Inst Nat Rech Cellules es modifiees et gene specifique de cellules es

Also Published As

Publication number Publication date
JP2004515212A (ja) 2004-05-27
FR2808803B1 (fr) 2004-12-10
NO20025402L (no) 2003-01-08
NO20025402D0 (no) 2002-11-11
FR2808803A1 (fr) 2001-11-16
ATE498011T1 (de) 2011-02-15
AU5488501A (en) 2001-11-20
US20040072169A1 (en) 2004-04-15
US20090151013A1 (en) 2009-06-11
WO2001085938A1 (fr) 2001-11-15
EP1280898B1 (de) 2011-02-09
NO331814B1 (no) 2012-04-10
BR0110764A (pt) 2003-05-06
AU2001254885B2 (en) 2006-08-10
ES2358731T3 (es) 2011-05-13
NZ522547A (en) 2006-02-24
CA2408732A1 (fr) 2001-11-15
EP1280898A1 (de) 2003-02-05
DK1280898T3 (da) 2011-05-16

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