DE60136229D1 - Verbessertes verfahren zur herstellung von cefuroxime axetil - Google Patents
Verbessertes verfahren zur herstellung von cefuroxime axetilInfo
- Publication number
- DE60136229D1 DE60136229D1 DE60136229T DE60136229T DE60136229D1 DE 60136229 D1 DE60136229 D1 DE 60136229D1 DE 60136229 T DE60136229 T DE 60136229T DE 60136229 T DE60136229 T DE 60136229T DE 60136229 D1 DE60136229 D1 DE 60136229D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- improved method
- cefuroxime axetil
- axetil
- cefuroxime
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- KEJCWVGMRLCZQQ-YJBYXUATSA-N Cefuroxime axetil Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-YJBYXUATSA-N 0.000 title 1
- 229960002620 cefuroxime axetil Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2001/000134 WO2003010170A1 (en) | 2001-07-25 | 2001-07-25 | An improved method for preparation of cefuroxime axetil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60136229D1 true DE60136229D1 (de) | 2008-11-27 |
Family
ID=11076368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60136229T Expired - Fee Related DE60136229D1 (de) | 2001-07-25 | 2001-07-25 | Verbessertes verfahren zur herstellung von cefuroxime axetil |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7064198B2 (de) |
| EP (1) | EP1409492B1 (de) |
| JP (1) | JP2004536870A (de) |
| CA (1) | CA2433067C (de) |
| DE (1) | DE60136229D1 (de) |
| WO (1) | WO2003010170A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN190849B (de) * | 2000-07-17 | 2003-08-23 | Ranbaxy Lab Ltd | |
| ITMI20011925A1 (it) * | 2001-09-14 | 2003-03-14 | Antibioticos Spa | Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino |
| CN100448879C (zh) * | 2004-07-22 | 2009-01-07 | 北京化工大学 | 一种无定型头孢呋辛酯的制备方法 |
| CN103435632B (zh) * | 2013-09-12 | 2016-03-02 | 广东立国制药有限公司 | 一种头孢呋辛酯的制备方法 |
| CN105131016A (zh) * | 2015-08-04 | 2015-12-09 | 江苏正大清江制药有限公司 | 一种头孢呋辛酯的制备方法 |
| CN106554361B (zh) * | 2016-09-30 | 2018-10-09 | 华北制药河北华民药业有限责任公司 | 一种头孢呋辛酯口服制剂的制备方法 |
| CN108066338B (zh) * | 2017-12-26 | 2020-04-24 | 磐安县道地磐药中药研究所 | 抗生素组合物及其制备方法 |
| CN110146621B (zh) * | 2019-06-13 | 2022-01-07 | 国药集团致君（深圳）制药有限公司 | 头孢类抗生素药物中聚合物的含量测定方法 |
| CN110590811B (zh) * | 2019-09-27 | 2022-05-03 | 广州白云山天心制药股份有限公司 | 一种头孢呋辛酯-3-烯异构体的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1094545A (en) * | 1976-02-16 | 1981-01-27 | Michael Gregson | Cephalosporin antibiotics |
| GB8810395D0 (en) | 1988-05-03 | 1988-06-08 | Glaxo Group Ltd | Chemical process |
| JP3121903B2 (ja) * | 1992-02-07 | 2001-01-09 | 塩野義製薬株式会社 | デアセチルセファロスポラン酸のカルバモイル化方法 |
| TW293010B (en) * | 1994-04-20 | 1996-12-11 | Hui-Po Wang | Method for preparing cephalosporin derivatives |
| IN190849B (de) * | 2000-07-17 | 2003-08-23 | Ranbaxy Lab Ltd | |
| ITMI20011925A1 (it) * | 2001-09-14 | 2003-03-14 | Antibioticos Spa | Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino |
-
2001
- 2001-07-25 JP JP2003515529A patent/JP2004536870A/ja active Pending
- 2001-07-25 EP EP01956755A patent/EP1409492B1/de not_active Expired - Lifetime
- 2001-07-25 CA CA2433067A patent/CA2433067C/en not_active Expired - Fee Related
- 2001-07-25 US US10/468,584 patent/US7064198B2/en not_active Expired - Fee Related
- 2001-07-25 WO PCT/IN2001/000134 patent/WO2003010170A1/en active Application Filing
- 2001-07-25 DE DE60136229T patent/DE60136229D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2433067A1 (en) | 2003-02-06 |
| JP2004536870A (ja) | 2004-12-09 |
| EP1409492A1 (de) | 2004-04-21 |
| US7064198B2 (en) | 2006-06-20 |
| EP1409492B1 (de) | 2008-10-15 |
| US20040077850A1 (en) | 2004-04-22 |
| WO2003010170A1 (en) | 2003-02-06 |
| CA2433067C (en) | 2010-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |