DE60135273D1 - Geschmacksmaskierte pharmazeutische Partikel - Google Patents

Geschmacksmaskierte pharmazeutische Partikel

Info

Publication number
DE60135273D1
DE60135273D1 DE60135273T DE60135273T DE60135273D1 DE 60135273 D1 DE60135273 D1 DE 60135273D1 DE 60135273 T DE60135273 T DE 60135273T DE 60135273 T DE60135273 T DE 60135273T DE 60135273 D1 DE60135273 D1 DE 60135273D1
Authority
DE
Germany
Prior art keywords
taste
pharmaceutical particles
masked pharmaceutical
masked
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60135273T
Other languages
English (en)
Inventor
Daniel Mcteigue
Narendra Parikh
David W Wynn
Ravivaj S Pillai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Application granted granted Critical
Publication of DE60135273D1 publication Critical patent/DE60135273D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60135273T 2000-06-30 2001-06-29 Geschmacksmaskierte pharmazeutische Partikel Expired - Lifetime DE60135273D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21550500P 2000-06-30 2000-06-30

Publications (1)

Publication Number Publication Date
DE60135273D1 true DE60135273D1 (de) 2008-09-25

Family

ID=22803235

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60135273T Expired - Lifetime DE60135273D1 (de) 2000-06-30 2001-06-29 Geschmacksmaskierte pharmazeutische Partikel

Country Status (17)

Country Link
US (2) US7223421B2 (de)
EP (1) EP1166777B1 (de)
JP (1) JP2002087952A (de)
KR (1) KR20020002321A (de)
CN (1) CN1356102A (de)
AR (1) AR029546A1 (de)
AT (1) ATE404180T1 (de)
AU (1) AU784613B2 (de)
BR (1) BR0103033A (de)
CA (1) CA2351814C (de)
CO (1) CO5271674A1 (de)
DE (1) DE60135273D1 (de)
ES (1) ES2311500T3 (de)
MX (1) MXPA01006803A (de)
NZ (1) NZ512683A (de)
SA (1) SA01220402B1 (de)
ZA (1) ZA200105407B (de)

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EP2266564B1 (de) 1997-12-22 2013-03-13 Euro-Celtique S.A. Peroral zu verabreichende Arzneiform enthaltend eine Kombination von einem opioid Agonisten und einem opioid Antagonisten
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
US8268333B2 (en) 2001-04-24 2012-09-18 Lintec Corporation Orally administered agent and an orally administered agent/supporting substrate complex
EP1387673B1 (de) 2001-05-11 2010-12-29 Endo Pharmaceuticals Inc. Opioid enthaltende arzneiform gegen missbrauch
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
RU2004129573A (ru) * 2002-04-04 2005-04-10 Пфайзер Продактс Инк. (Us) Жевательная таблетка с приятным вкусом
NZ535286A (en) * 2002-04-05 2007-07-27 Euro Celtique Sa Matrix for sustained, invariant and independent release of active compounds
US8092831B2 (en) * 2002-11-08 2012-01-10 Andrx Pharmaceuticals, Llc Antihistamine and decongestant system
US20040258752A1 (en) * 2003-01-31 2004-12-23 Paruthi Manoj Kumar Taste masking pharmaceutical composition and process for its preparation
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
US20040213838A1 (en) * 2003-04-24 2004-10-28 Mazer Terrence B. Medical food tablets containing free amino acids
US20040265373A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
US20040265372A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
JPWO2005000358A1 (ja) * 2003-06-27 2006-08-03 湧永製薬株式会社 安定液剤
JP3881640B2 (ja) * 2003-08-08 2007-02-14 塩野義製薬株式会社 ロラタジンを含むドライシロップ剤
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US8062659B2 (en) * 2004-02-20 2011-11-22 Novartis Ag Dietary fiber composition
US20050186271A1 (en) * 2004-02-24 2005-08-25 Sheskey Paul J. Process for dispersing a fluid in a mass of solid particles
EP1604666A1 (de) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
EP1604667A1 (de) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioide zur Behandlung des Restless Leg Syndroms
ITMI20042356A1 (it) * 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
EA015615B1 (ru) * 2005-01-28 2011-10-31 Еуро-Селтик С.А. Устойчивые к спиртам лекарственные формы
EP1695700A1 (de) * 2005-02-28 2006-08-30 Euro-Celtique S.A. Darreichungsform enthaltend Oxycodon und Naloxon
EP1702558A1 (de) 2005-02-28 2006-09-20 Euro-Celtique S.A. Verfahren und Vorrichtung zur Darmtätigkeitserfassung
EP1813276A1 (de) * 2006-01-27 2007-08-01 Euro-Celtique S.A. Manipulationssichere Dosierformen
WO2007123153A1 (ja) * 2006-04-19 2007-11-01 Ono Pharmaceutical Co., Ltd. 経口投与用カプセル
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
CA2654402A1 (en) * 2006-06-01 2007-12-06 Adel Penhasi Multiple unit pharmaceutical formulation
US20080031927A1 (en) * 2006-07-11 2008-02-07 Catani Steven J Solid oral dosage vitamin and mineral compositions
AU2007308986A1 (en) * 2006-10-25 2008-05-02 Mcneil-Ppc, Inc. Ibuprofen composition
FR2930147B1 (fr) * 2008-04-18 2013-02-08 Flamel Tech Sa Forme orale solide dotee d'un double profil de liberation
PE20110422A1 (es) * 2008-07-07 2011-07-01 Euro Celtique Sa Composicion farmaceutica que comprende antagonistas opioides
TR201900199T4 (tr) 2009-03-10 2019-02-21 Euro Celtique Sa Oksikodon ve nalokson içeren çabuk salımlı farmasötik bileşimler.
US20100239681A1 (en) * 2009-03-20 2010-09-23 Biokey, Inc. Controlled Release Particulates Containing Water-Insoluble Drug
AU2011237122B2 (en) * 2010-03-31 2014-06-12 Mochida Pharmaceutical Co., Ltd. Easily dosable solid preparation
CN103813807B (zh) 2011-09-30 2017-02-08 持田制药株式会社 易服用性固体制剂
FR2999426B1 (fr) * 2012-12-13 2015-01-02 Flamel Tech Sa Forme orale multiparticulaire a liberation immediate d'au moins un compose actif, comprenant des particules enrobees resistantes au broyage.
JP5836980B2 (ja) * 2013-01-11 2015-12-24 信越化学工業株式会社 薬物含有粒子、固形製剤及び薬物含有粒子の製造方法
MY183489A (en) 2013-07-23 2021-02-22 Euro Celtique Sa A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
EP3288556A4 (de) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Oral zerfallende zusammensetzungen
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CN112674348A (zh) * 2020-12-23 2021-04-20 石药集团中诺药业（泰州）有限公司 一种b族维生素含片和咀嚼片制备方法
WO2024020361A2 (en) * 2022-07-19 2024-01-25 Michael Ogburn Inhalable serotonin receptor agonist formulations

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JPS48103718A (de) 1972-04-14 1973-12-26
US4160827A (en) * 1978-02-06 1979-07-10 The Upjohn Company Metronidazole phosphate and salts
JPS5535031A (en) 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
JPS57120518A (en) * 1981-01-19 1982-07-27 Tanabe Seiyaku Co Ltd Preparation of microcapsule
US4749575A (en) 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4971791A (en) 1985-08-26 1990-11-20 The Procter & Gamble Company Taste masking compositions
US4800087A (en) 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4916161A (en) 1988-10-25 1990-04-10 Bristol-Myers Squibb Taste-masking pharmaceutical agents
US5084278A (en) 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
CA2063141C (en) * 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
IT1246383B (it) 1990-04-17 1994-11-18 Eurand Int Metodo per il mascheramento del sapore di farmaci
FI922107A0 (fi) 1991-05-10 1992-05-08 Faulding F H & Co Ltd Mikrokapselkomposition och foerfarande.
US5837277A (en) 1992-06-04 1998-11-17 Smithkline Beecham Corporation Palatable pharmaceutical compositions
DK0621032T3 (da) 1993-04-23 2000-10-23 Novartis Ag Lægemiddelform med reguleret afgivelse
ZA945944B (en) 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
GB9317897D0 (en) * 1993-08-27 1993-10-13 Plessey Telecomm Telecommunications switching element
JPH07223970A (ja) 1994-02-10 1995-08-22 Tanabe Seiyaku Co Ltd 消化管内適所放出製剤
US5536507A (en) 1994-06-24 1996-07-16 Bristol-Myers Squibb Company Colonic drug delivery system
JP3355593B2 (ja) * 1994-08-19 2002-12-09 信越化学工業株式会社 固形腸溶製剤の製造方法
BR9711585A (pt) 1996-10-01 2000-01-18 Cima Labs Inc Composição de microcápsula, com sabor mascarado, de um remédio solúvel em água, formulação farmacêutica para administrar um remédio, e, processo para disfarçar o sabor de um remédio.
US6046177A (en) 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations

Also Published As

Publication number Publication date
JP2002087952A (ja) 2002-03-27
CO5271674A1 (es) 2003-04-30
EP1166777B1 (de) 2008-08-13
US7223421B2 (en) 2007-05-29
CN1356102A (zh) 2002-07-03
CA2351814A1 (en) 2001-12-30
ATE404180T1 (de) 2008-08-15
AU784613B2 (en) 2006-05-11
SA01220402B1 (ar) 2007-02-07
KR20020002321A (ko) 2002-01-09
AR029546A1 (es) 2003-07-02
AU5415801A (en) 2002-01-03
US20070196489A1 (en) 2007-08-23
ZA200105407B (en) 2003-01-02
ES2311500T3 (es) 2009-02-16
MXPA01006803A (es) 2003-08-20
US20020031552A1 (en) 2002-03-14
BR0103033A (pt) 2002-03-05
NZ512683A (en) 2003-02-28
CA2351814C (en) 2009-11-17
EP1166777A1 (de) 2002-01-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition