DE60134275D1 - Polynukleotide zur bestimmung von kolonkrebs - Google Patents
Polynukleotide zur bestimmung von kolonkrebsInfo
- Publication number
- DE60134275D1 DE60134275D1 DE60134275T DE60134275T DE60134275D1 DE 60134275 D1 DE60134275 D1 DE 60134275D1 DE 60134275 T DE60134275 T DE 60134275T DE 60134275 T DE60134275 T DE 60134275T DE 60134275 D1 DE60134275 D1 DE 60134275D1
- Authority
- DE
- Germany
- Prior art keywords
- colon
- polynucleotides
- differentially expressed
- determination
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 206010009944 Colon cancer Diseases 0.000 abstract 2
- 208000029742 colonic neoplasm Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000004804 Adenomatous Polyps Diseases 0.000 abstract 1
- 206010055114 Colon cancer metastatic Diseases 0.000 abstract 1
- 208000019399 Colonic disease Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 201000010989 colorectal carcinoma Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001394 metastastic effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21183500P | 2000-06-15 | 2000-06-15 | |
| PCT/US2001/019313 WO2001096523A2 (en) | 2000-06-15 | 2001-06-15 | Polynucleotides related to colon cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60134275D1 true DE60134275D1 (de) | 2008-07-10 |
Family
ID=22788525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60134275T Expired - Lifetime DE60134275D1 (de) | 2000-06-15 | 2001-06-15 | Polynukleotide zur bestimmung von kolonkrebs |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20030008284A1 (enExample) |
| EP (2) | EP1370684B1 (enExample) |
| JP (2) | JP5363695B2 (enExample) |
| AT (1) | ATE397094T1 (enExample) |
| AU (1) | AU2001269867A1 (enExample) |
| DE (1) | DE60134275D1 (enExample) |
| ES (2) | ES2305087T3 (enExample) |
| PT (1) | PT1370684E (enExample) |
| WO (1) | WO2001096523A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060035237A1 (en) | 2002-08-26 | 2006-02-16 | Markowitz Sanford D | Methods and compositions for categorizing patients |
| US7118912B2 (en) * | 2002-08-26 | 2006-10-10 | Case Western Reserve University | Methods and compositions for categorizing patients |
| WO2004018648A2 (en) * | 2002-08-26 | 2004-03-04 | Case Western Reserve University | Methods for treating patients and identifying therapeutics |
| CA2500731A1 (en) * | 2002-10-02 | 2004-04-15 | Robert Y. L. Tsai | Methods for controlling proliferation of cells |
| JP4712692B2 (ja) * | 2004-06-02 | 2011-06-29 | Tssバイオテック株式会社 | 癌の診断と治療において有用な新規ポリペプチド |
| DE102004037860A1 (de) * | 2004-08-04 | 2006-03-16 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Turmormarker zur Diagnose von Karzinomen und/oder davon abstammender Metastasen |
| US8435490B2 (en) * | 2007-06-21 | 2013-05-07 | The Johns Hopkins University | Small peptides specifically bind to colorectal cancers |
| CA2736170A1 (en) | 2007-09-06 | 2009-03-12 | Case Western Reserve University | Methods for diagnosing and treating cancers |
| SG189774A1 (en) | 2008-04-10 | 2013-05-31 | Genenews Corp | Method and apparatus for determining a probability of colorectal cancer in a subject |
Family Cites Families (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668777A (en) | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
| US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5206152A (en) | 1988-04-08 | 1993-04-27 | Arch Development Corporation | Cloning and expression of early growth regulatory protein genes |
| US5010175A (en) | 1988-05-02 | 1991-04-23 | The Regents Of The University Of California | General method for producing and selecting peptides with specific properties |
| US5422120A (en) | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
| AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
| EP0454781B1 (en) | 1989-01-23 | 1998-12-16 | Chiron Corporation | Recombinant cells for therapies of infection and hyperproliferative disorders and preparation thereof |
| DE69034168T3 (de) | 1989-03-21 | 2013-04-11 | Vical, Inc. | Expression von exogenen Polynukleotidsequenzen in Wirbeltieren |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| EP1645635A3 (en) | 1989-08-18 | 2010-07-07 | Oxford Biomedica (UK) Limited | Replication defective recombinant retroviruses expressing a palliative |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| NZ237464A (en) | 1990-03-21 | 1995-02-24 | Depotech Corp | Liposomes with at least two separate chambers encapsulating two separate biologically active substances |
| US5252296A (en) | 1990-05-15 | 1993-10-12 | Chiron Corporation | Method and apparatus for biopolymer synthesis |
| US5149655A (en) | 1990-06-21 | 1992-09-22 | Agracetus, Inc. | Apparatus for genetic transformation |
| RU2142467C1 (ru) | 1990-07-27 | 1999-12-10 | Чирон Диагностикс Корпорейшн | Полинуклеотиды, способ их получения, гибридизационный анализ нуклеиновой кислоты |
| JP3337214B2 (ja) | 1990-12-20 | 2002-10-21 | アーチ・ディベロップメント・コーポレーション | 電離線による遺伝子発現の調節 |
| DE69233013T2 (de) | 1991-08-20 | 2004-03-04 | The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer | Adenovirus vermittelter gentransfer in den gastrointestinaltrakt |
| WO1993010218A1 (en) | 1991-11-14 | 1993-05-27 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Vectors including foreign genes and negative selective markers |
| GB9125623D0 (en) | 1991-12-02 | 1992-01-29 | Dynal As | Cell modification |
| WO1993014778A1 (en) | 1992-01-23 | 1993-08-05 | Vical, Inc. | Ex vivo gene transfer |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| JPH07507689A (ja) | 1992-06-08 | 1995-08-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 特定組織のターゲティング方法及び組成物 |
| JPH09507741A (ja) | 1992-06-10 | 1997-08-12 | アメリカ合衆国 | ヒト血清による不活性化に耐性のあるベクター粒子 |
| GB2269175A (en) | 1992-07-31 | 1994-02-02 | Imperial College | Retroviral vectors |
| CA2592997A1 (en) | 1992-12-03 | 1994-06-09 | Genzyme Corporation | Pseudo-adenovirus vectors |
| AU6818094A (en) | 1993-04-22 | 1994-11-08 | Depotech Corporation | Cyclodextrin liposomes encapsulating pharmacologic compounds and methods for their use |
| JP3532566B2 (ja) | 1993-06-24 | 2004-05-31 | エル. グラハム,フランク | 遺伝子治療のためのアデノウイルスベクター |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5500356A (en) | 1993-08-10 | 1996-03-19 | Life Technologies, Inc. | Method of nucleic acid sequence selection |
| US6015686A (en) | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| EP0694070B1 (en) | 1993-09-15 | 2002-04-10 | Chiron Corporation | Recombinant alphavirus vectors |
| JP3875990B2 (ja) | 1993-10-25 | 2007-01-31 | カンジ,インコーポレイテッド | 組換えアデノウイルスベクターおよび使用方法 |
| NZ276305A (en) | 1993-11-16 | 1997-10-24 | Depotech Corp | Controlled release vesicle compositions |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US5631734A (en) | 1994-02-10 | 1997-05-20 | Affymetrix, Inc. | Method and apparatus for detection of fluorescently labeled materials |
| WO1995030763A2 (en) | 1994-05-09 | 1995-11-16 | Chiron Viagene, Inc. | Retroviral vectors having a reduced recombination rate |
| US5571639A (en) | 1994-05-24 | 1996-11-05 | Affymax Technologies N.V. | Computer-aided engineering system for design of sequence arrays and lithographic masks |
| US5474397A (en) | 1994-05-31 | 1995-12-12 | Ingersoll-Rand Company | Drum access mechanism |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| WO1997027317A1 (en) | 1996-01-23 | 1997-07-31 | Affymetrix, Inc. | Nucleic acid analysis techniques |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US6974666B1 (en) | 1994-10-21 | 2005-12-13 | Appymetric, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
| WO1996017072A2 (en) | 1994-11-30 | 1996-06-06 | Chiron Viagene, Inc. | Recombinant alphavirus vectors |
| US5783387A (en) | 1995-02-06 | 1998-07-21 | The Regents Of The University Of California | Method for identifying and quantifying nucleic acid sequence aberrations |
| US5599695A (en) | 1995-02-27 | 1997-02-04 | Affymetrix, Inc. | Printing molecular library arrays using deprotection agents solely in the vapor phase |
| AU700952B2 (en) | 1995-06-07 | 1999-01-14 | Pioneer Hi-Bred International, Inc. | PCR-based cDNA subtractive cloning method |
| US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| US5654173A (en) | 1996-08-23 | 1997-08-05 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| US5981279A (en) * | 1995-11-09 | 1999-11-09 | Allegheny University Of The Health Sciences | Compositions and methods to regulate calmodulin gene expression, and uses thereof for influencing cell growth and differentiation |
| JP2001507563A (ja) | 1995-11-23 | 2001-06-12 | キャンサー リサーチ キャンペーン テクノロジー リミテッド | Brca2癌感受性遺伝子の同定及び配列決定に関する材料及び方法並びにそれらの使用 |
| AU2189397A (en) | 1996-02-08 | 1997-08-28 | Affymetrix, Inc. | Chip-based speciation and phenotypic characterization of microorganisms |
| US6458530B1 (en) | 1996-04-04 | 2002-10-01 | Affymetrix Inc. | Selecting tag nucleic acids |
| AU2998597A (en) | 1996-05-06 | 1997-11-26 | Chiron Corporation | Crossless retroviral vectors |
| US6251433B1 (en) | 1996-08-13 | 2001-06-26 | Chiron Corporation | Polycationic polymers |
| US6007991A (en) * | 1997-03-28 | 1999-12-28 | The Research Foundation Of Suny | Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer |
| US6197332B1 (en) | 1997-08-13 | 2001-03-06 | Chiron Corporation | Lipid-conjugated polyamide compounds and related compositions and methods thereof |
| AU1726199A (en) * | 1997-12-31 | 1999-07-19 | Chiron Corporation | Metastatic cancer regulated gene |
| JP2002519000A (ja) * | 1998-01-28 | 2002-07-02 | カイロン コーポレイション | ヒト遺伝子および遺伝子発現産物ii |
| AU764441B2 (en) * | 1998-02-09 | 2003-08-21 | Genset S.A. | cDNAs encoding secreted proteins |
| DE19820190A1 (de) * | 1998-04-28 | 1999-11-04 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Pankreas-Tumor |
| DE69938190T2 (de) * | 1998-10-15 | 2009-03-05 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Gene mit veränderter expression in metastatischen brust- oder dickdarm- krebszellen |
| PT1144609E (pt) | 1999-08-27 | 2008-05-28 | Novartis Vaccines & Diagnostic | Oligonucleótidos anti-sentido quiméricos e suas formulações para transfecção de células |
-
2001
- 2001-06-15 ES ES01948414T patent/ES2305087T3/es not_active Expired - Lifetime
- 2001-06-15 US US09/883,152 patent/US20030008284A1/en not_active Abandoned
- 2001-06-15 WO PCT/US2001/019313 patent/WO2001096523A2/en not_active Ceased
- 2001-06-15 AU AU2001269867A patent/AU2001269867A1/en not_active Abandoned
- 2001-06-15 AT AT01948414T patent/ATE397094T1/de active
- 2001-06-15 ES ES08006693T patent/ES2398391T3/es not_active Expired - Lifetime
- 2001-06-15 EP EP01948414A patent/EP1370684B1/en not_active Expired - Lifetime
- 2001-06-15 JP JP2002510643A patent/JP5363695B2/ja not_active Expired - Fee Related
- 2001-06-15 DE DE60134275T patent/DE60134275D1/de not_active Expired - Lifetime
- 2001-06-15 EP EP08006693A patent/EP1953243B1/en not_active Expired - Lifetime
- 2001-06-15 PT PT01948414T patent/PT1370684E/pt unknown
-
2011
- 2011-08-09 JP JP2011174312A patent/JP2011254830A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011254830A (ja) | 2011-12-22 |
| EP1953243A8 (en) | 2008-11-19 |
| ES2305087T3 (es) | 2008-11-01 |
| JP2004503238A (ja) | 2004-02-05 |
| AU2001269867A1 (en) | 2001-12-24 |
| EP1370684A2 (en) | 2003-12-17 |
| EP1370684B1 (en) | 2008-05-28 |
| WO2001096523A3 (en) | 2003-07-10 |
| EP1953243A3 (en) | 2008-11-05 |
| ES2398391T3 (es) | 2013-03-15 |
| EP1953243B1 (en) | 2012-12-26 |
| PT1370684E (pt) | 2008-09-08 |
| US20030008284A1 (en) | 2003-01-09 |
| EP1953243A2 (en) | 2008-08-06 |
| JP5363695B2 (ja) | 2013-12-11 |
| ATE397094T1 (de) | 2008-06-15 |
| WO2001096523A2 (en) | 2001-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |