DK0858467T3 - Materialer og fremgangsmåder angående identifikationen og sekventeringen af BRCA2 cancerfölsomhedsgen og anvendelser deraf - Google Patents
Materialer og fremgangsmåder angående identifikationen og sekventeringen af BRCA2 cancerfölsomhedsgen og anvendelser derafInfo
- Publication number
- DK0858467T3 DK0858467T3 DK96939218T DK96939218T DK0858467T3 DK 0858467 T3 DK0858467 T3 DK 0858467T3 DK 96939218 T DK96939218 T DK 96939218T DK 96939218 T DK96939218 T DK 96939218T DK 0858467 T3 DK0858467 T3 DK 0858467T3
- Authority
- DK
- Denmark
- Prior art keywords
- brca2
- sequencing
- identification
- materials
- methods
- Prior art date
Links
- 101150008921 Brca2 gene Proteins 0.000 title abstract 7
- 108700020462 BRCA2 Proteins 0.000 title abstract 5
- 102000052609 BRCA2 Human genes 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 238000012163 sequencing technique Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000035945 sensitivity Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108700010154 BRCA2 Genes Proteins 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 108700028369 Alleles Proteins 0.000 abstract 1
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010033128 Ovarian cancer Diseases 0.000 abstract 1
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9523959.6A GB9523959D0 (en) | 1995-11-23 | 1995-11-23 | Materials and methods relating to the diagnosis and prophylactic and therapeutic treatment of cancer |
GBGB9525555.0A GB9525555D0 (en) | 1995-12-14 | 1995-12-14 | Materials and methods relating to the diagnosis and prophylactic and therapeutic treatment of cancer |
GBGB9617961.9A GB9617961D0 (en) | 1996-08-28 | 1996-08-28 | Materials and methods relating to the diagnosis and prophylactic and therapeuti treatment of cancer |
PCT/GB1996/002904 WO1997019110A1 (en) | 1995-11-23 | 1996-11-25 | Materials and methods relating to the identification and sequencing of the brca2 cancer susceptibility gene and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0858467T3 true DK0858467T3 (da) | 2004-06-14 |
Family
ID=27267991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96939218T DK0858467T3 (da) | 1995-11-23 | 1996-11-25 | Materialer og fremgangsmåder angående identifikationen og sekventeringen af BRCA2 cancerfölsomhedsgen og anvendelser deraf |
Country Status (10)
Country | Link |
---|---|
US (1) | US6045997A (da) |
EP (1) | EP0858467B1 (da) |
JP (1) | JP2001507563A (da) |
AT (1) | ATE259378T1 (da) |
AU (1) | AU707636C (da) |
CA (1) | CA2238010A1 (da) |
DE (1) | DE69631540T2 (da) |
DK (1) | DK0858467T3 (da) |
ES (1) | ES2217328T3 (da) |
WO (1) | WO1997019110A1 (da) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
CA2239733C (en) * | 1995-12-18 | 2001-04-03 | Myriad Genetics, Inc. | Chromosome 13-linked breast cancer susceptibility gene |
AU773601B2 (en) * | 1995-12-18 | 2004-05-27 | Endorecherche Inc. | Chromosome 13-linked breast cancer susceptibility gene |
US5837492A (en) | 1995-12-18 | 1998-11-17 | Myriad Genetics, Inc. | Chromosome 13-linked breast cancer susceptibility gene |
US20030022184A1 (en) * | 1996-02-12 | 2003-01-30 | Oncormed. Inc. | Coding sequences of the human BRCA1 gene |
US6838256B2 (en) | 1996-02-12 | 2005-01-04 | Gene Logic Inc. | Coding sequences of the human BRCA1 gene |
DE69830395T2 (de) * | 1997-03-20 | 2006-01-26 | Affymetrix, Inc. (n.d.Ges.d.Staates Delaware), Santa Clara | Iterative resequenzierung |
US20140302494A9 (en) * | 1997-08-15 | 2014-10-09 | Myriad Genetics, Incorporated | Method of analyzing a brca2 gene in a human subject |
WO1999009164A1 (en) * | 1997-08-15 | 1999-02-25 | Oncormed, Inc. | Coding sequence haplotypes of the human brca2 gene |
US20090269814A1 (en) * | 1998-05-22 | 2009-10-29 | Murphy Patricia D | Method of Analyzing a BRCA2 Gene in a Human Subject |
US6207370B1 (en) | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
US6492109B1 (en) | 1997-09-23 | 2002-12-10 | Gene Logic, Inc. | Susceptibility mutation 6495delGC of BRCA2 |
US6686163B2 (en) | 1998-05-06 | 2004-02-03 | Gene Logic Inc. | Coding sequence haplotype of the human BRCA1 gene |
US6562958B1 (en) * | 1998-06-09 | 2003-05-13 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Acinetobacter baumannii for diagnostics and therapeutics |
US20030180789A1 (en) * | 1998-12-30 | 2003-09-25 | Dale Roderic M.K. | Arrays with modified oligonucleotide and polynucleotide compositions |
US6087112A (en) * | 1998-12-30 | 2000-07-11 | Oligos Etc. Inc. | Arrays with modified oligonucleotide and polynucleotide compositions |
DE60025704T2 (de) * | 1999-02-24 | 2006-09-07 | Juan Saus | Das goodpasture-antigen bindende protein |
EP1287162A2 (en) | 1999-10-21 | 2003-03-05 | Case Western Reserve University | Gene expression profiling of inflammatory bowel disease |
AT409381B (de) * | 2000-03-03 | 2002-07-25 | Gloessl Josef Dr | Xylosyltransferase-gen |
US6727353B2 (en) * | 2000-04-14 | 2004-04-27 | Icagen, Inc. | Nucleic acid encoding Kv10.1, a voltage-gated potassium channel from human brain |
EP1953243B1 (en) | 2000-06-15 | 2012-12-26 | Novartis Vaccines and Diagnostics, Inc. | Polynucleotides related to colon cancer |
WO2002004628A2 (en) | 2000-07-06 | 2002-01-17 | Genvec, Inc. | Method of identifying a binding partner of a gene product |
DE50015173D1 (de) | 2000-07-13 | 2008-07-03 | Ct Concept Technologie Ag | Verfahren und vorrichtung zur zustandsabhängigen regelung des transienten verhaltens von leistungshalbleiterschaltern |
US20030175749A1 (en) * | 2001-12-08 | 2003-09-18 | Jong-Yoon Chun | Annealing control primer and its uses |
WO2003104429A2 (en) * | 2002-06-10 | 2003-12-18 | Idec Pharmaceuticals Corporation | Genes overexpressed by ovarian cancer and their use in developing novel therapeutics |
US7461048B2 (en) * | 2003-07-21 | 2008-12-02 | Aureon Laboratories, Inc. | Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition |
US7892823B2 (en) * | 2007-02-06 | 2011-02-22 | Geneprotech, Inc. | Methods and systems for high homologous recombination (“HR”) targeting efficiency |
US8759089B2 (en) * | 2007-02-06 | 2014-06-24 | Geneprotech, Inc. | Methods and systems for high homologous recombination (“HR”) targeting efficiency |
US20130058979A1 (en) * | 2009-11-30 | 2013-03-07 | Agency For Science, Technology And Research | Treatment and prevention of cancers associated with intracellular oncoproteins by antibody therapy or vaccination |
ES2896404T3 (es) | 2014-04-04 | 2022-02-24 | Crown Bioscience Inc Taicang | Métodos para determinar la capacidad de respuesta a inhibidores de MEK/ERK |
US11773449B2 (en) | 2017-09-01 | 2023-10-03 | The Hospital For Sick Children | Profiling and treatment of hypermutant cancer |
CN116179710B (zh) * | 2023-03-14 | 2023-11-24 | 成都诺森医学检验有限公司 | 基于高通量测序平台的brca1/2基因突变检测的引物组、文库构建与环化方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0393502B1 (en) * | 1989-04-19 | 1995-12-27 | F. Hoffmann-La Roche Ag | Soluble interferon-gamma receptors and methods for their production |
US5464758A (en) * | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
EP0739894A4 (en) * | 1994-01-14 | 1997-03-26 | Taisho Pharmaceutical Co Ltd | THIAZOLINE DERIVATIVE |
WO1995019369A1 (en) * | 1994-01-14 | 1995-07-20 | Vanderbilt University | Method for detection and treatment of breast cancer |
-
1996
- 1996-11-25 AU AU76350/96A patent/AU707636C/en not_active Ceased
- 1996-11-25 DE DE69631540T patent/DE69631540T2/de not_active Revoked
- 1996-11-25 AT AT96939218T patent/ATE259378T1/de active
- 1996-11-25 US US08/755,587 patent/US6045997A/en not_active Expired - Fee Related
- 1996-11-25 CA CA002238010A patent/CA2238010A1/en not_active Abandoned
- 1996-11-25 EP EP96939218A patent/EP0858467B1/en not_active Revoked
- 1996-11-25 DK DK96939218T patent/DK0858467T3/da active
- 1996-11-25 WO PCT/GB1996/002904 patent/WO1997019110A1/en active IP Right Grant
- 1996-11-25 JP JP51952797A patent/JP2001507563A/ja active Pending
- 1996-11-25 ES ES96939218T patent/ES2217328T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69631540T2 (de) | 2005-01-27 |
EP0858467B1 (en) | 2004-02-11 |
AU7635096A (en) | 1997-06-11 |
AU707636C (en) | 2003-01-16 |
WO1997019110A1 (en) | 1997-05-29 |
ATE259378T1 (de) | 2004-02-15 |
AU707636B2 (en) | 1999-07-15 |
US6045997A (en) | 2000-04-04 |
CA2238010A1 (en) | 1997-05-29 |
DE69631540D1 (de) | 2004-03-18 |
ES2217328T3 (es) | 2004-11-01 |
EP0858467A1 (en) | 1998-08-19 |
JP2001507563A (ja) | 2001-06-12 |
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