DE60133102T2 - Fischimpstoff gegen piscirickettsia salmonis - Google Patents
Fischimpstoff gegen piscirickettsia salmonis Download PDFInfo
- Publication number
- DE60133102T2 DE60133102T2 DE60133102T DE60133102T DE60133102T2 DE 60133102 T2 DE60133102 T2 DE 60133102T2 DE 60133102 T DE60133102 T DE 60133102T DE 60133102 T DE60133102 T DE 60133102T DE 60133102 T2 DE60133102 T2 DE 60133102T2
- Authority
- DE
- Germany
- Prior art keywords
- acid sequence
- amino acid
- piscirickettsia salmonis
- sequence
- clone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000192126 Piscirickettsia salmonis Species 0.000 title claims abstract description 55
- 235000001674 Agaricus brunnescens Nutrition 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract description 56
- 150000007523 nucleic acids Chemical class 0.000 claims abstract description 33
- 239000000427 antigen Substances 0.000 claims abstract description 20
- 102000036639 antigens Human genes 0.000 claims abstract description 20
- 108091007433 antigens Proteins 0.000 claims abstract description 20
- 241000251468 Actinopterygii Species 0.000 claims abstract description 9
- 108020004707 nucleic acids Proteins 0.000 claims abstract description 7
- 102000039446 nucleic acids Human genes 0.000 claims abstract description 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 35
- 108090000623 proteins and genes Proteins 0.000 claims description 28
- 102000004169 proteins and genes Human genes 0.000 claims description 20
- 230000028993 immune response Effects 0.000 claims description 12
- 238000013519 translation Methods 0.000 claims description 8
- 238000002405 diagnostic procedure Methods 0.000 claims description 6
- 238000013518 transcription Methods 0.000 claims description 6
- 230000035897 transcription Effects 0.000 claims description 6
- 239000002299 complementary DNA Substances 0.000 claims description 3
- 101710163595 Chaperone protein DnaK Proteins 0.000 claims description 2
- 101710178376 Heat shock 70 kDa protein Proteins 0.000 claims description 2
- 101710152018 Heat shock cognate 70 kDa protein Proteins 0.000 claims description 2
- 241000189072 typhus group Species 0.000 claims description 2
- 238000001514 detection method Methods 0.000 claims 2
- 102100034374 S-phase kinase-associated protein 2 Human genes 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 abstract description 10
- 235000019688 fish Nutrition 0.000 abstract description 8
- 241000972773 Aulopiformes Species 0.000 abstract description 5
- 235000019515 salmon Nutrition 0.000 abstract description 5
- 208000015181 infectious disease Diseases 0.000 abstract description 3
- 108700026244 Open Reading Frames Proteins 0.000 description 27
- 239000002773 nucleotide Substances 0.000 description 15
- 125000003729 nucleotide group Chemical group 0.000 description 15
- 108090000765 processed proteins & peptides Proteins 0.000 description 11
- 238000002255 vaccination Methods 0.000 description 10
- 108020004414 DNA Proteins 0.000 description 9
- 238000003752 polymerase chain reaction Methods 0.000 description 9
- 102100036563 26S proteasome regulatory subunit 8 Human genes 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 108091093088 Amplicon Proteins 0.000 description 4
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 description 3
- 241001280377 Oncorhynchus tshawytscha Species 0.000 description 3
- 241000606651 Rickettsiales Species 0.000 description 3
- 206010040047 Sepsis Diseases 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 229940023146 nucleic acid vaccine Drugs 0.000 description 3
- 208000013223 septicemia Diseases 0.000 description 3
- 241000589242 Legionella pneumophila Species 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 241000192127 Piscirickettsia Species 0.000 description 2
- 208000037113 Piscirickettsiaceae Infections Diseases 0.000 description 2
- 241000277263 Salmo Species 0.000 description 2
- 241000544286 Vibrio anguillarum Species 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 210000000987 immune system Anatomy 0.000 description 2
- 229940115932 legionella pneumophila Drugs 0.000 description 2
- 210000001161 mammalian embryo Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 108020004999 messenger RNA Proteins 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 238000012340 reverse transcriptase PCR Methods 0.000 description 2
- 102000021527 ATP binding proteins Human genes 0.000 description 1
- 108091011108 ATP binding proteins Proteins 0.000 description 1
- 102000005416 ATP-Binding Cassette Transporters Human genes 0.000 description 1
- 108010006533 ATP-Binding Cassette Transporters Proteins 0.000 description 1
- 102000034263 Amino acid transporters Human genes 0.000 description 1
- 108050005273 Amino acid transporters Proteins 0.000 description 1
- 108010077805 Bacterial Proteins Proteins 0.000 description 1
- 101100232929 Caenorhabditis elegans pat-4 gene Proteins 0.000 description 1
- 101100507655 Canis lupus familiaris HSPA1 gene Proteins 0.000 description 1
- 241001445332 Coxiella <snail> Species 0.000 description 1
- 108010074124 Escherichia coli Proteins Proteins 0.000 description 1
- 101000839464 Leishmania braziliensis Heat shock 70 kDa protein Proteins 0.000 description 1
- 101710175243 Major antigen Proteins 0.000 description 1
- 101710116435 Outer membrane protein Proteins 0.000 description 1
- 241000277331 Salmonidae Species 0.000 description 1
- 102000008579 Transposases Human genes 0.000 description 1
- 108010020764 Transposases Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000002308 embryonic cell Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007852 inverse PCR Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000007862 touchdown PCR Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/29—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0005838 | 2000-03-11 | ||
| GBGB0005838.8A GB0005838D0 (en) | 2000-03-11 | 2000-03-11 | Sequence |
| GBGB0016082.0A GB0016082D0 (en) | 2000-07-01 | 2000-07-01 | Sequence 3 |
| GBGB0016080.4A GB0016080D0 (en) | 2000-07-01 | 2000-07-01 | Sequence 2 |
| GB0016082 | 2000-07-01 | ||
| GB0016080 | 2000-07-01 | ||
| GBGB0018599.1A GB0018599D0 (en) | 2000-07-29 | 2000-07-29 | Sequence 4 |
| GB0018599 | 2000-07-29 | ||
| PCT/GB2001/001055 WO2001068865A2 (en) | 2000-03-11 | 2001-03-12 | Fish vaccine against piscirickettsia salmonis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60133102D1 DE60133102D1 (enExample) | 2008-04-17 |
| DE60133102T2 true DE60133102T2 (de) | 2009-03-12 |
Family
ID=35060803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60133102T Expired - Lifetime DE60133102T2 (de) | 2000-03-11 | 2001-03-12 | Fischimpstoff gegen piscirickettsia salmonis |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7842296B2 (enExample) |
| AT (1) | ATE388231T1 (enExample) |
| CY (1) | CY1107374T1 (enExample) |
| DE (1) | DE60133102T2 (enExample) |
| DK (1) | DK1282710T3 (enExample) |
| ES (1) | ES2300321T3 (enExample) |
| NO (2) | NO20110559L (enExample) |
| PT (1) | PT1282710E (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2113511A4 (en) | 2006-12-22 | 2010-09-15 | Soluciones Biotecnologicas Inn | DNA VACCINES FOR FISH |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO329958B1 (no) | 1999-09-17 | 2011-01-31 | Pfizer Canada Inc | Anvendelse av en immunogen mengde av OspA-lipoprotein fra Piscirickettsia salmonis, OspA-antigen, og immunogene promiskuose TCE i et OspA-kimaert fusjonsprotein, for fremstilling av medikamenter, og immunologisk in vitro-fremgangsmate for deteksjon av humoralt antistoff mot OspA eller P. salmonis. |
| CA2381708C (en) | 2001-08-27 | 2011-10-18 | Universidad Catolica De Valparaiso | Immunogenic protein against piscirickettsia salmonis |
-
2001
- 2001-03-12 DE DE60133102T patent/DE60133102T2/de not_active Expired - Lifetime
- 2001-03-12 PT PT01911869T patent/PT1282710E/pt unknown
- 2001-03-12 DK DK01911869T patent/DK1282710T3/da active
- 2001-03-12 AT AT01911869T patent/ATE388231T1/de not_active IP Right Cessation
- 2001-03-12 ES ES01911869T patent/ES2300321T3/es not_active Expired - Lifetime
-
2004
- 2004-08-06 US US10/913,883 patent/US7842296B2/en not_active Expired - Fee Related
-
2008
- 2008-03-31 CY CY20081100360T patent/CY1107374T1/el unknown
-
2011
- 2011-04-12 NO NO20110559A patent/NO20110559L/no unknown
- 2011-09-21 NO NO20111282A patent/NO339732B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1282710E (pt) | 2008-04-08 |
| DE60133102D1 (enExample) | 2008-04-17 |
| ES2300321T3 (es) | 2008-06-16 |
| NO20110559L (no) | 2002-09-10 |
| ATE388231T1 (de) | 2008-03-15 |
| NO339732B1 (no) | 2017-01-23 |
| DK1282710T3 (da) | 2008-07-07 |
| US7842296B2 (en) | 2010-11-30 |
| NO20111282A1 (no) | 2002-09-10 |
| CY1107374T1 (el) | 2012-12-19 |
| US20050226895A1 (en) | 2005-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |