DE60132637D1 - Verfahren zur herstellung von pyrimidinonverbindungen und deren pharmazeutisch unbedenklichen salzen - Google Patents
Verfahren zur herstellung von pyrimidinonverbindungen und deren pharmazeutisch unbedenklichen salzenInfo
- Publication number
- DE60132637D1 DE60132637D1 DE60132637T DE60132637T DE60132637D1 DE 60132637 D1 DE60132637 D1 DE 60132637D1 DE 60132637 T DE60132637 T DE 60132637T DE 60132637 T DE60132637 T DE 60132637T DE 60132637 D1 DE60132637 D1 DE 60132637D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceuticalally
- salts
- production
- pyrimidinone compounds
- pyrimidinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/KR2001/001583 WO2003024956A1 (en) | 2001-09-21 | 2001-09-21 | Method for preparing pyrimidinone compound and pharmaceutically acceptable salts thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60132637D1 true DE60132637D1 (de) | 2008-03-13 |
DE60132637T2 DE60132637T2 (de) | 2009-01-15 |
Family
ID=19198449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60132637T Expired - Lifetime DE60132637T2 (de) | 2001-09-21 | 2001-09-21 | Verfahren zum herstellen von pyrimidionverbindungen und deren pharmazeutisch unbedenklichen salzen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7309788B2 (de) |
EP (1) | EP1436283B1 (de) |
JP (1) | JP4268871B2 (de) |
CN (1) | CN1273465C (de) |
AU (1) | AU2001292386B2 (de) |
CA (1) | CA2461060C (de) |
DE (1) | DE60132637T2 (de) |
MX (1) | MXPA04002653A (de) |
WO (1) | WO2003024956A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2726811C (en) | 2008-06-06 | 2019-11-26 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Survival predictor for diffuse large b cell lymphoma |
KR101058284B1 (ko) | 2010-01-22 | 2011-08-22 | 보령제약 주식회사 | 2-(2-n-부틸-4-히드록시-6-메틸-피리미딘-5-일)-N,N-디메틸아세트아미드의 신규한 제조방법 |
CN104610164B (zh) * | 2010-01-21 | 2018-03-16 | 保宁制药株式会社 | 2‑(2‑正丁基‑4‑羟基‑6‑甲基‑嘧啶‑5‑基)‑n,n‑二甲基乙酰胺的制备方法 |
KR101226332B1 (ko) | 2010-01-21 | 2013-01-24 | 보령제약 주식회사 | 2-(2-n-부틸-4-히드록시-6-메틸-피리미딘-5-일)-N,N-디메틸아세트아미드의 신규한 제조방법 |
CN102485227B (zh) * | 2010-12-02 | 2015-06-10 | 鲁南制药集团股份有限公司 | 一种药物组合物及其用途 |
CN102485228B (zh) * | 2010-12-02 | 2015-06-10 | 鲁南制药集团股份有限公司 | 一种药物组合物及其用途 |
US8765776B2 (en) * | 2011-04-12 | 2014-07-01 | Boryung Pharmaceutical Co., Ltd. | Antihypertensive pharmaceutical composition |
KR101490329B1 (ko) * | 2012-10-12 | 2015-02-04 | 보령제약 주식회사 | 피마살탄 포타슘염의 일수화물 결정, 그 제조방법, 및 그를 포함하는 약제학적 조성물 |
PT2968316T (pt) | 2013-03-13 | 2019-10-29 | Forma Therapeutics Inc | Derivados de 2-hidroxi-1-{4-[(4-fenilfenil)carbonil]piperazin-1-il}etano-1-ona e compostos relacionados como inibidores da sintase de ácidos gordos (fasn) para o tratamento do cancro |
EP3066215B1 (de) | 2013-11-06 | 2019-04-24 | The United States of America, represented by the Secretary, Department of Health and Human Services | Methode zur lymphoma typisierung mit hilfe von expressionsmarker bestimmung |
CN105837514B (zh) * | 2016-01-29 | 2018-09-18 | 北京睿创康泰医药研究院有限公司 | 非马沙坦药物杂质的制备方法 |
CN107586289A (zh) * | 2017-09-13 | 2018-01-16 | 潍坊新益制药技术有限公司 | 非马沙坦钾盐三水合物的制备方法 |
CN107973784B (zh) * | 2017-11-16 | 2021-08-24 | 珠海市海瑞德生物科技有限公司 | 一种非马沙坦的合成方法 |
TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
CN113382633A (zh) | 2018-10-29 | 2021-09-10 | 福马治疗股份有限公司 | (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式 |
CN109485640B (zh) * | 2018-12-24 | 2021-03-26 | 合肥创新医药技术有限公司 | 一种非马沙坦杂质的制备方法 |
KR102221856B1 (ko) * | 2020-10-12 | 2021-03-02 | 유니셀랩 주식회사 | 신규한 피마살탄 결정형의 다형체 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100300566B1 (ko) * | 1994-09-17 | 2001-11-22 | 조생현 | 피리미디논유도체와그의제조방법및용도 |
KR19990081093A (ko) * | 1998-04-25 | 1999-11-15 | 조생현 | 피리미디논 화합물, 이를 함유하는 약제학적 조성물 및 이의제조방법 |
-
2001
- 2001-09-21 US US10/490,294 patent/US7309788B2/en not_active Expired - Lifetime
- 2001-09-21 DE DE60132637T patent/DE60132637T2/de not_active Expired - Lifetime
- 2001-09-21 AU AU2001292386A patent/AU2001292386B2/en not_active Expired
- 2001-09-21 EP EP01972742A patent/EP1436283B1/de not_active Expired - Lifetime
- 2001-09-21 JP JP2003528803A patent/JP4268871B2/ja not_active Expired - Lifetime
- 2001-09-21 MX MXPA04002653A patent/MXPA04002653A/es active IP Right Grant
- 2001-09-21 WO PCT/KR2001/001583 patent/WO2003024956A1/en active IP Right Grant
- 2001-09-21 CA CA2461060A patent/CA2461060C/en not_active Expired - Lifetime
- 2001-09-21 CN CNB018237452A patent/CN1273465C/zh not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1273465C (zh) | 2006-09-06 |
EP1436283B1 (de) | 2008-01-23 |
WO2003024956A1 (en) | 2003-03-27 |
CA2461060C (en) | 2010-07-27 |
CN1558906A (zh) | 2004-12-29 |
DE60132637T2 (de) | 2009-01-15 |
EP1436283A4 (de) | 2004-12-08 |
US20040266800A1 (en) | 2004-12-30 |
US7309788B2 (en) | 2007-12-18 |
EP1436283A1 (de) | 2004-07-14 |
CA2461060A1 (en) | 2003-03-27 |
AU2001292386B2 (en) | 2006-06-22 |
MXPA04002653A (es) | 2004-07-08 |
JP2005504800A (ja) | 2005-02-17 |
JP4268871B2 (ja) | 2009-05-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |