DE60129445D1 - Quinolin-derivate als antientzündungsmittel - Google Patents

Quinolin-derivate als antientzündungsmittel

Info

Publication number
DE60129445D1
DE60129445D1 DE60129445T DE60129445T DE60129445D1 DE 60129445 D1 DE60129445 D1 DE 60129445D1 DE 60129445 T DE60129445 T DE 60129445T DE 60129445 T DE60129445 T DE 60129445T DE 60129445 D1 DE60129445 D1 DE 60129445D1
Authority
DE
Germany
Prior art keywords
inflammatory agent
quinoline derivatives
quinoline
derivatives
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60129445T
Other languages
English (en)
Other versions
DE60129445T2 (de
Inventor
Chris Allen Broka
Woongki Kim
Kevin Lee Mclaren
David Bernard Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60129445D1 publication Critical patent/DE60129445D1/de
Application granted granted Critical
Publication of DE60129445T2 publication Critical patent/DE60129445T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
DE60129445T 2000-08-09 2001-08-01 Quinolin-derivate als antientzündungsmittel Expired - Fee Related DE60129445T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22419600P 2000-08-09 2000-08-09
US224196P 2000-08-09
PCT/EP2001/008880 WO2002012192A1 (en) 2000-08-09 2001-08-01 Quinolene derivatives as anti-inflammation agents

Publications (2)

Publication Number Publication Date
DE60129445D1 true DE60129445D1 (de) 2007-08-30
DE60129445T2 DE60129445T2 (de) 2008-04-24

Family

ID=22839655

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60129445T Expired - Fee Related DE60129445T2 (de) 2000-08-09 2001-08-01 Quinolin-derivate als antientzündungsmittel

Country Status (15)

Country Link
US (2) US7049325B2 (de)
EP (1) EP1313707B1 (de)
JP (1) JP3930428B2 (de)
KR (1) KR20030027016A (de)
CN (1) CN1199950C (de)
AR (1) AR033554A1 (de)
AT (1) ATE367379T1 (de)
AU (1) AU2001277560A1 (de)
BR (1) BR0113175A (de)
CA (1) CA2418832A1 (de)
DE (1) DE60129445T2 (de)
ES (1) ES2290161T3 (de)
MX (1) MXPA03001178A (de)
WO (1) WO2002012192A1 (de)
ZA (1) ZA200300847B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW591089B (en) * 2001-08-09 2004-06-11 Cheil Ind Inc Slurry composition for use in chemical mechanical polishing of metal wiring
GB0220953D0 (en) * 2002-09-10 2002-10-23 Novartis Ag Organic compounds
US7132432B2 (en) * 2003-06-05 2006-11-07 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)
KR101514953B1 (ko) * 2005-03-08 2015-04-24 베링거 인겔하임 인터내셔날 게엠베하 매크로사이클릭 화합물의 제조방법
WO2010033443A1 (en) * 2008-09-17 2010-03-25 Boehringer Ingelheim International Gmbh Combination of hcv ns3 protease inhibitor with interferon and ribavirin
NZ598465A (en) 2009-10-30 2013-10-25 Boehringer Ingelheim Int Dosage regimens for hcv combination therapy comprising bi201335, interferon alpha and ribavirin
US9383448B2 (en) 2012-07-05 2016-07-05 Deca System Co., Ltd. Golf GPS device with automatic hole recognition and playing hole selection

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9018134D0 (en) * 1989-09-29 1990-10-03 Ici Plc Heterocyclic derivatives
MX9200299A (es) 1991-02-07 1992-12-01 Roussel Uclaf Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
JP3531944B2 (ja) 1991-02-07 2004-05-31 アベンティス・ファーマ・ソシエテ・アノニム 新規のベンジル基で置換された窒素系二環式誘導体及びその製造方法
GB9311790D0 (en) * 1993-06-08 1993-07-28 Minnesota Mining & Mfg Photothermographic materials
DK122693D0 (da) 1993-10-29 1993-10-29 Hempels Skibsfarve Fab J C Marin struktur
EP0830133A1 (de) * 1995-04-28 1998-03-25 Takeda Chemical Industries, Ltd. Therapeutische zusammensetzung für arthritis
DE19638486A1 (de) * 1996-09-20 1998-03-26 Basf Ag Hetaroylderivate
DE19638484A1 (de) * 1996-09-20 1998-03-26 Basf Ag Hetaroylderivate
US6069151A (en) 1996-11-06 2000-05-30 Darwin Discovery, Ltd. Quinolines and their therapeutic use
IT1298159B1 (it) * 1997-01-28 1999-12-20 Hoffmann La Roche Derivati di un 5-aroilnaftalene
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6034256A (en) 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
US6479438B2 (en) * 2001-01-04 2002-11-12 Isp Investments Inc. Gel inhibited liquid carrier for a biocide containing a carbodiimide and an emulsifier mixture

Also Published As

Publication number Publication date
US20020082276A1 (en) 2002-06-27
AU2001277560A1 (en) 2002-02-18
MXPA03001178A (es) 2003-06-30
CA2418832A1 (en) 2002-02-14
JP3930428B2 (ja) 2007-06-13
CN1466575A (zh) 2004-01-07
ZA200300847B (en) 2004-04-30
DE60129445T2 (de) 2008-04-24
WO2002012192A1 (en) 2002-02-14
JP2004505951A (ja) 2004-02-26
EP1313707A1 (de) 2003-05-28
US20060084677A1 (en) 2006-04-20
US7049325B2 (en) 2006-05-23
AR033554A1 (es) 2003-12-26
ATE367379T1 (de) 2007-08-15
US7186840B2 (en) 2007-03-06
EP1313707B1 (de) 2007-07-18
ES2290161T3 (es) 2008-02-16
BR0113175A (pt) 2004-02-17
KR20030027016A (ko) 2003-04-03
CN1199950C (zh) 2005-05-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee