DE60128115D1 - Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davon - Google Patents
Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davonInfo
- Publication number
- DE60128115D1 DE60128115D1 DE60128115T DE60128115T DE60128115D1 DE 60128115 D1 DE60128115 D1 DE 60128115D1 DE 60128115 T DE60128115 T DE 60128115T DE 60128115 T DE60128115 T DE 60128115T DE 60128115 D1 DE60128115 D1 DE 60128115D1
- Authority
- DE
- Germany
- Prior art keywords
- polypeptides
- ema
- group
- streptococcal
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 10
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 10
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 10
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000193990 Streptococcus sp. 'group B' Species 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 241000194032 Enterococcus faecalis Species 0.000 abstract 1
- 241000193996 Streptococcus pyogenes Species 0.000 abstract 1
- -1 antibodies thereto Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63434100A | 2000-08-08 | 2000-08-08 | |
US634341 | 2000-08-08 | ||
PCT/US2001/024795 WO2002012294A2 (en) | 2000-08-08 | 2001-08-08 | Group b streptococcus polypeptides nucleic acids and therapeutic compositions and vaccines thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60128115D1 true DE60128115D1 (de) | 2007-06-06 |
DE60128115T2 DE60128115T2 (de) | 2008-03-06 |
Family
ID=24543390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60128115T Expired - Lifetime DE60128115T2 (de) | 2000-08-08 | 2001-08-08 | Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davon |
Country Status (11)
Country | Link |
---|---|
US (2) | US7128919B2 (de) |
EP (2) | EP1810978B1 (de) |
AT (1) | ATE360640T1 (de) |
AU (1) | AU2001281168A1 (de) |
CA (1) | CA2417357A1 (de) |
CY (1) | CY1107702T1 (de) |
DE (1) | DE60128115T2 (de) |
DK (1) | DK1320542T3 (de) |
ES (1) | ES2286133T3 (de) |
PT (1) | PT1320542E (de) |
WO (1) | WO2002012294A2 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ560966A (en) | 2000-10-27 | 2010-06-25 | Novartis Vaccines & Diagnostic | Nucleic acids and proteins from streptococcus groups A & B |
GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
US20070053924A1 (en) * | 2002-08-26 | 2007-03-08 | Herve Tettelin | Conserved and specific streptococcal genomes |
EP1648500B1 (de) | 2003-07-31 | 2014-07-09 | Novartis Vaccines and Diagnostics, Inc. | Immunogene zusammensetzungen für streptococcus pyogenes |
US20070110763A1 (en) * | 2003-08-15 | 2007-05-17 | Stephane Rioux | Polypeptides of streptococcus pyogenes |
US8945589B2 (en) | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
CA2575548A1 (en) * | 2004-07-29 | 2006-07-27 | John L. Telford | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
SI1786908T1 (sl) * | 2004-08-18 | 2010-06-30 | Bayer Cropscience Ag | Rastline s povečano plastidno aktivnostjo R encima ki fosforilira škrob |
WO2006042027A2 (en) * | 2004-10-08 | 2006-04-20 | Novartis Vaccines And Diagnostics Inc. | Immunogenic and therapeutic compositions for streptococcus pyogenes |
CA2586058A1 (en) | 2004-11-01 | 2006-05-11 | Dennis L. Kasper | Modified streptococcal polysaccharides and uses thereof |
GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
PT2054431E (pt) * | 2006-06-09 | 2011-11-03 | Novartis Ag | Confórmeros de adesinas bacterianas |
WO2008108830A2 (en) * | 2006-10-30 | 2008-09-12 | Novartis Ag | Immunogenic and therapeutic compositions for streptococcus pyogenes |
JP5653215B2 (ja) | 2007-09-12 | 2015-01-14 | ノバルティス アーゲー | Gas57変異体抗原およびgas57抗体 |
ES2391695T3 (es) | 2007-12-21 | 2012-11-29 | Novartis Ag | Formas mutantes de estreptolisina O |
WO2010080836A2 (en) * | 2009-01-06 | 2010-07-15 | C3 Jian, Inc. | Antibacterial and antifungal peptides |
EP2385842A1 (de) * | 2009-01-12 | 2011-11-16 | Novartis AG | Cna_b-domänen-antigene in impfstoffen gegen grampositive bakterien |
CN103391714A (zh) * | 2010-12-10 | 2013-11-13 | 默沙东公司 | 减轻搅动引起的免疫原性组合物聚集的新制剂 |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
MX2021013736A (es) | 2019-05-10 | 2021-12-10 | Glaxosmithkline Biologicals Sa | Produccion de conjugados. |
CN115287244B (zh) * | 2022-06-28 | 2023-07-25 | 北部湾大学 | 鱼源无乳链球菌internalin基因LRR结构域敲除突变株及其制备方法和应用 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3654090A (en) | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
USRE31006E (en) | 1968-09-24 | 1982-08-03 | Akzona Incorporated | Process for the demonstration and determination of reaction components having specific binding affinity for each other |
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
US4342566A (en) | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
US4356263A (en) | 1980-06-09 | 1982-10-26 | President And Fellows Of Harvard College | Method of making a polysaccharide vaccine |
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4631211A (en) | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
US5302386A (en) | 1986-04-16 | 1994-04-12 | Brigham And Women's Hospital, Inc. | Bacterial antigens, antibodies, vaccines and methods of manufacture |
US5010175A (en) | 1988-05-02 | 1991-04-23 | The Regents Of The University Of California | General method for producing and selecting peptides with specific properties |
JP2989002B2 (ja) | 1988-12-22 | 1999-12-13 | キリン―アムジエン・インコーポレーテツド | 化学修飾顆粒球コロニー刺激因子 |
US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
US5648241A (en) | 1989-09-15 | 1997-07-15 | The General Hospital Corporation | Conjugate vaccine against group B streptococcus |
US5139749A (en) | 1990-06-22 | 1992-08-18 | Tas, Inc. | Fluidized calcining process |
EP0573608A1 (de) | 1991-02-07 | 1993-12-15 | Molecumetics, Ltd. | Konformationseingeschränkte mimetika für beta-schleifen und beta-bögen und diese enthaltende peptide |
WO1992016192A1 (en) | 1991-03-15 | 1992-10-01 | Amgen Inc. | Pulmonary administration of granulocyte colony stimulating factor |
EP0667787B1 (de) | 1992-09-24 | 2001-07-18 | Brigham And Women's Hospital | Gruppe b streptococcus typ ii und typ v polysaccharid-protein konjugate als impfstoffe |
ZA937034B (en) | 1992-09-24 | 1995-06-23 | Brigham & Womens Hospital | Group B streptococcus type II and type V polysaccharide-protein conjugate vaccines |
DK1310510T3 (da) | 1993-05-27 | 2007-09-24 | Aventis Pharma Inc | Topologisk adsilte, kodede biblioteker med fast fase |
US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
JP2001505061A (ja) * | 1996-02-29 | 2001-04-17 | ワシントン ユニヴァーシティ | バクテリア性エラスチン結合タンパク、これをコードする核酸配列およびこれを使用した診断並びに治療方法 |
CA2289116A1 (en) | 1997-05-06 | 1998-11-12 | Human Genome Sciences, Inc. | Enterococcus faecalis polynucleotides and polypeptides |
WO2000006737A2 (en) | 1998-07-27 | 2000-02-10 | Microbial Technics Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
EP1100920A2 (de) | 1998-07-27 | 2001-05-23 | Microbial Technics Limited | Nukleinsaüren und entsprechende proteine aus gruppe-b streptococcus |
WO2000012132A1 (en) | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
CA2365523A1 (en) | 1999-04-15 | 2000-10-26 | The Regents Of The University Of California | Identification of sortase gene |
WO2000078787A1 (en) | 1999-06-21 | 2000-12-28 | University Of Utah Research Foundation | ISOLATED GENES FROM VIRULENT GROUP B $i(STREPTOCOCCUS AGALACTIAE) |
US9002545B2 (en) | 2011-01-07 | 2015-04-07 | Wabtec Holding Corp. | Data improvement system and method |
-
2001
- 2001-08-08 EP EP07002407A patent/EP1810978B1/de not_active Expired - Lifetime
- 2001-08-08 DK DK01959633T patent/DK1320542T3/da active
- 2001-08-08 DE DE60128115T patent/DE60128115T2/de not_active Expired - Lifetime
- 2001-08-08 AT AT01959633T patent/ATE360640T1/de active
- 2001-08-08 US US10/333,002 patent/US7128919B2/en not_active Expired - Fee Related
- 2001-08-08 AU AU2001281168A patent/AU2001281168A1/en not_active Abandoned
- 2001-08-08 WO PCT/US2001/024795 patent/WO2002012294A2/en active IP Right Grant
- 2001-08-08 CA CA002417357A patent/CA2417357A1/en not_active Abandoned
- 2001-08-08 EP EP01959633A patent/EP1320542B9/de not_active Expired - Lifetime
- 2001-08-08 ES ES01959633T patent/ES2286133T3/es not_active Expired - Lifetime
- 2001-08-08 PT PT01959633T patent/PT1320542E/pt unknown
-
2006
- 2006-07-26 US US11/493,705 patent/US7645577B2/en not_active Expired - Fee Related
-
2007
- 2007-07-19 CY CY20071100967T patent/CY1107702T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT1320542E (pt) | 2007-08-06 |
ES2286133T3 (es) | 2007-12-01 |
DK1320542T3 (da) | 2007-09-10 |
EP1320542A2 (de) | 2003-06-25 |
US7128919B2 (en) | 2006-10-31 |
WO2002012294A2 (en) | 2002-02-14 |
EP1810978A2 (de) | 2007-07-25 |
EP1320542B1 (de) | 2007-04-25 |
US20040071729A1 (en) | 2004-04-15 |
ATE360640T1 (de) | 2007-05-15 |
EP1320542B9 (de) | 2007-09-12 |
CY1107702T1 (el) | 2013-04-18 |
US7645577B2 (en) | 2010-01-12 |
AU2001281168A1 (en) | 2002-02-18 |
WO2002012294A3 (en) | 2003-04-10 |
CA2417357A1 (en) | 2002-02-14 |
EP1810978A3 (de) | 2007-10-24 |
US20070178116A1 (en) | 2007-08-02 |
EP1810978B1 (de) | 2013-02-13 |
DE60128115T2 (de) | 2008-03-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |