DE60128115D1 - Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davon - Google Patents

Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davon

Info

Publication number
DE60128115D1
DE60128115D1 DE60128115T DE60128115T DE60128115D1 DE 60128115 D1 DE60128115 D1 DE 60128115D1 DE 60128115 T DE60128115 T DE 60128115T DE 60128115 T DE60128115 T DE 60128115T DE 60128115 D1 DE60128115 D1 DE 60128115D1
Authority
DE
Germany
Prior art keywords
polypeptides
ema
group
streptococcal
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128115T
Other languages
English (en)
Other versions
DE60128115T2 (de
Inventor
Elisabeth Adderson
John Bohnsack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah Research Foundation UURF
St Jude Childrens Research Hospital
Original Assignee
University of Utah Research Foundation UURF
St Jude Childrens Research Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah Research Foundation UURF, St Jude Childrens Research Hospital filed Critical University of Utah Research Foundation UURF
Publication of DE60128115D1 publication Critical patent/DE60128115D1/de
Application granted granted Critical
Publication of DE60128115T2 publication Critical patent/DE60128115T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60128115T 2000-08-08 2001-08-08 Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davon Expired - Lifetime DE60128115T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63434100A 2000-08-08 2000-08-08
US634341 2000-08-08
PCT/US2001/024795 WO2002012294A2 (en) 2000-08-08 2001-08-08 Group b streptococcus polypeptides nucleic acids and therapeutic compositions and vaccines thereof

Publications (2)

Publication Number Publication Date
DE60128115D1 true DE60128115D1 (de) 2007-06-06
DE60128115T2 DE60128115T2 (de) 2008-03-06

Family

ID=24543390

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128115T Expired - Lifetime DE60128115T2 (de) 2000-08-08 2001-08-08 Gruppe-b streptococcus polypeptide, nukleinsäure, therapeutische zusammensetzungen und impfstoffe davon

Country Status (11)

Country Link
US (2) US7128919B2 (de)
EP (2) EP1810978B1 (de)
AT (1) ATE360640T1 (de)
AU (1) AU2001281168A1 (de)
CA (1) CA2417357A1 (de)
CY (1) CY1107702T1 (de)
DE (1) DE60128115T2 (de)
DK (1) DK1320542T3 (de)
ES (1) ES2286133T3 (de)
PT (1) PT1320542E (de)
WO (1) WO2002012294A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ560966A (en) 2000-10-27 2010-06-25 Novartis Vaccines & Diagnostic Nucleic acids and proteins from streptococcus groups A & B
GB0107661D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
US20070053924A1 (en) * 2002-08-26 2007-03-08 Herve Tettelin Conserved and specific streptococcal genomes
EP1648500B1 (de) 2003-07-31 2014-07-09 Novartis Vaccines and Diagnostics, Inc. Immunogene zusammensetzungen für streptococcus pyogenes
US20070110763A1 (en) * 2003-08-15 2007-05-17 Stephane Rioux Polypeptides of streptococcus pyogenes
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
CA2575548A1 (en) * 2004-07-29 2006-07-27 John L. Telford Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
SI1786908T1 (sl) * 2004-08-18 2010-06-30 Bayer Cropscience Ag Rastline s povečano plastidno aktivnostjo R encima ki fosforilira škrob
WO2006042027A2 (en) * 2004-10-08 2006-04-20 Novartis Vaccines And Diagnostics Inc. Immunogenic and therapeutic compositions for streptococcus pyogenes
CA2586058A1 (en) 2004-11-01 2006-05-11 Dennis L. Kasper Modified streptococcal polysaccharides and uses thereof
GB0502095D0 (en) 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
PT2054431E (pt) * 2006-06-09 2011-11-03 Novartis Ag Confórmeros de adesinas bacterianas
WO2008108830A2 (en) * 2006-10-30 2008-09-12 Novartis Ag Immunogenic and therapeutic compositions for streptococcus pyogenes
JP5653215B2 (ja) 2007-09-12 2015-01-14 ノバルティス アーゲー Gas57変異体抗原およびgas57抗体
ES2391695T3 (es) 2007-12-21 2012-11-29 Novartis Ag Formas mutantes de estreptolisina O
WO2010080836A2 (en) * 2009-01-06 2010-07-15 C3 Jian, Inc. Antibacterial and antifungal peptides
EP2385842A1 (de) * 2009-01-12 2011-11-16 Novartis AG Cna_b-domänen-antigene in impfstoffen gegen grampositive bakterien
CN103391714A (zh) * 2010-12-10 2013-11-13 默沙东公司 减轻搅动引起的免疫原性组合物聚集的新制剂
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
MX2021013736A (es) 2019-05-10 2021-12-10 Glaxosmithkline Biologicals Sa Produccion de conjugados.
CN115287244B (zh) * 2022-06-28 2023-07-25 北部湾大学 鱼源无乳链球菌internalin基因LRR结构域敲除突变株及其制备方法和应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
USRE31006E (en) 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4342566A (en) 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
US4356263A (en) 1980-06-09 1982-10-26 President And Fellows Of Harvard College Method of making a polysaccharide vaccine
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US5302386A (en) 1986-04-16 1994-04-12 Brigham And Women's Hospital, Inc. Bacterial antigens, antibodies, vaccines and methods of manufacture
US5010175A (en) 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
JP2989002B2 (ja) 1988-12-22 1999-12-13 キリン―アムジエン・インコーポレーテツド 化学修飾顆粒球コロニー刺激因子
US5354844A (en) 1989-03-16 1994-10-11 Boehringer Ingelheim International Gmbh Protein-polycation conjugates
US5648241A (en) 1989-09-15 1997-07-15 The General Hospital Corporation Conjugate vaccine against group B streptococcus
US5139749A (en) 1990-06-22 1992-08-18 Tas, Inc. Fluidized calcining process
EP0573608A1 (de) 1991-02-07 1993-12-15 Molecumetics, Ltd. Konformationseingeschränkte mimetika für beta-schleifen und beta-bögen und diese enthaltende peptide
WO1992016192A1 (en) 1991-03-15 1992-10-01 Amgen Inc. Pulmonary administration of granulocyte colony stimulating factor
EP0667787B1 (de) 1992-09-24 2001-07-18 Brigham And Women's Hospital Gruppe b streptococcus typ ii und typ v polysaccharid-protein konjugate als impfstoffe
ZA937034B (en) 1992-09-24 1995-06-23 Brigham & Womens Hospital Group B streptococcus type II and type V polysaccharide-protein conjugate vaccines
DK1310510T3 (da) 1993-05-27 2007-09-24 Aventis Pharma Inc Topologisk adsilte, kodede biblioteker med fast fase
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
JP2001505061A (ja) * 1996-02-29 2001-04-17 ワシントン ユニヴァーシティ バクテリア性エラスチン結合タンパク、これをコードする核酸配列およびこれを使用した診断並びに治療方法
CA2289116A1 (en) 1997-05-06 1998-11-12 Human Genome Sciences, Inc. Enterococcus faecalis polynucleotides and polypeptides
WO2000006737A2 (en) 1998-07-27 2000-02-10 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
EP1100920A2 (de) 1998-07-27 2001-05-23 Microbial Technics Limited Nukleinsaüren und entsprechende proteine aus gruppe-b streptococcus
WO2000012132A1 (en) 1998-08-31 2000-03-09 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
CA2365523A1 (en) 1999-04-15 2000-10-26 The Regents Of The University Of California Identification of sortase gene
WO2000078787A1 (en) 1999-06-21 2000-12-28 University Of Utah Research Foundation ISOLATED GENES FROM VIRULENT GROUP B $i(STREPTOCOCCUS AGALACTIAE)
US9002545B2 (en) 2011-01-07 2015-04-07 Wabtec Holding Corp. Data improvement system and method

Also Published As

Publication number Publication date
PT1320542E (pt) 2007-08-06
ES2286133T3 (es) 2007-12-01
DK1320542T3 (da) 2007-09-10
EP1320542A2 (de) 2003-06-25
US7128919B2 (en) 2006-10-31
WO2002012294A2 (en) 2002-02-14
EP1810978A2 (de) 2007-07-25
EP1320542B1 (de) 2007-04-25
US20040071729A1 (en) 2004-04-15
ATE360640T1 (de) 2007-05-15
EP1320542B9 (de) 2007-09-12
CY1107702T1 (el) 2013-04-18
US7645577B2 (en) 2010-01-12
AU2001281168A1 (en) 2002-02-18
WO2002012294A3 (en) 2003-04-10
CA2417357A1 (en) 2002-02-14
EP1810978A3 (de) 2007-10-24
US20070178116A1 (en) 2007-08-02
EP1810978B1 (de) 2013-02-13
DE60128115T2 (de) 2008-03-06

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