DK1320542T3 - Gruppe B streptokokpolypeptider-nukleinsyrer og terapeutiske sammensætninger og vacciner deraf - Google Patents
Gruppe B streptokokpolypeptider-nukleinsyrer og terapeutiske sammensætninger og vacciner derafInfo
- Publication number
- DK1320542T3 DK1320542T3 DK01959633T DK01959633T DK1320542T3 DK 1320542 T3 DK1320542 T3 DK 1320542T3 DK 01959633 T DK01959633 T DK 01959633T DK 01959633 T DK01959633 T DK 01959633T DK 1320542 T3 DK1320542 T3 DK 1320542T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptides
- nucleic acids
- ema
- streptococcal
- group
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 10
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 10
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 10
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 241000194032 Enterococcus faecalis Species 0.000 abstract 1
- 241000193996 Streptococcus pyogenes Species 0.000 abstract 1
- -1 antibodies thereto Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63434100A | 2000-08-08 | 2000-08-08 | |
PCT/US2001/024795 WO2002012294A2 (en) | 2000-08-08 | 2001-08-08 | Group b streptococcus polypeptides nucleic acids and therapeutic compositions and vaccines thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1320542T3 true DK1320542T3 (da) | 2007-09-10 |
Family
ID=24543390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01959633T DK1320542T3 (da) | 2000-08-08 | 2001-08-08 | Gruppe B streptokokpolypeptider-nukleinsyrer og terapeutiske sammensætninger og vacciner deraf |
Country Status (11)
Country | Link |
---|---|
US (2) | US7128919B2 (da) |
EP (2) | EP1320542B9 (da) |
AT (1) | ATE360640T1 (da) |
AU (1) | AU2001281168A1 (da) |
CA (1) | CA2417357A1 (da) |
CY (1) | CY1107702T1 (da) |
DE (1) | DE60128115T2 (da) |
DK (1) | DK1320542T3 (da) |
ES (1) | ES2286133T3 (da) |
PT (1) | PT1320542E (da) |
WO (1) | WO2002012294A2 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2189473A3 (en) * | 2000-10-27 | 2010-08-11 | Novartis Vaccines and Diagnostics S.r.l. | Nucleic and proteins from streptococcus groups A & B |
GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
EP1597348A4 (en) * | 2002-08-26 | 2010-03-31 | Novartis Vaccines & Diagnostic | GENES OF STREPTOCOCCUS PRESERVED OR SPECIFIC |
CA2532369C (en) * | 2003-07-31 | 2016-07-26 | Chiron Corporation | Immunogenic compositions for streptococcus pyogenes |
CA2535863A1 (en) * | 2003-08-15 | 2005-02-24 | Id Biomedical Corporation | Polypeptides of streptococcus pyogenes |
US8945589B2 (en) * | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
CA2575548A1 (en) * | 2004-07-29 | 2006-07-27 | John L. Telford | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
EP1786908B1 (en) * | 2004-08-18 | 2010-03-03 | Bayer CropScience AG | Plants with increased plastidic activity of r3 starch-phosphorylating enzyme |
CA2583803C (en) * | 2004-10-08 | 2014-11-25 | Giuliano Bensi | Immunogenic and therapeutic compositions for streptococcus pyogenes |
US7858101B2 (en) | 2004-11-01 | 2010-12-28 | The Brigham And Women's Hospital, Inc. | Modified streptococcal polysaccharides and uses thereof |
GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
WO2008020335A2 (en) * | 2006-06-09 | 2008-02-21 | Novartis Ag | Immunogenic compositions for streptococcus agalactiae |
EP2094297A2 (en) * | 2006-10-30 | 2009-09-02 | Novartis AG | Immunogenic and therapeutic compositions for streptococcus pyogenes |
WO2009034473A2 (en) | 2007-09-12 | 2009-03-19 | Novartis Ag | Gas57 mutant antigens and gas57 antibodies |
CN101977926B (zh) | 2007-12-21 | 2014-10-08 | 诺华股份有限公司 | 链球菌溶血素o的突变形式 |
AU2010203698B2 (en) | 2009-01-06 | 2016-07-21 | C3 Jian, Inc. | Targeted antimicrobial moieties |
MX2011007456A (es) * | 2009-01-12 | 2011-08-03 | Novartis Ag | Antigenos del dominio de proteina de superficie de union a colageno tipo b (can_b) en vacunas contra bacteria gram positiva. |
WO2012078482A1 (en) * | 2010-12-10 | 2012-06-14 | Merck Sharp & Dohme Corp. | Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
BR112021022429A2 (pt) | 2019-05-10 | 2022-03-22 | Glaxosmithkline Biologicals Sa | Produção de conjugados |
CN115287244B (zh) * | 2022-06-28 | 2023-07-25 | 北部湾大学 | 鱼源无乳链球菌internalin基因LRR结构域敲除突变株及其制备方法和应用 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3654090A (en) | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
USRE31006E (en) | 1968-09-24 | 1982-08-03 | Akzona Incorporated | Process for the demonstration and determination of reaction components having specific binding affinity for each other |
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
US4342566A (en) | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
US4356263A (en) | 1980-06-09 | 1982-10-26 | President And Fellows Of Harvard College | Method of making a polysaccharide vaccine |
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4631211A (en) | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
US5302386A (en) | 1986-04-16 | 1994-04-12 | Brigham And Women's Hospital, Inc. | Bacterial antigens, antibodies, vaccines and methods of manufacture |
US5010175A (en) | 1988-05-02 | 1991-04-23 | The Regents Of The University Of California | General method for producing and selecting peptides with specific properties |
CA2006596C (en) | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
US5648241A (en) | 1989-09-15 | 1997-07-15 | The General Hospital Corporation | Conjugate vaccine against group B streptococcus |
US5139749A (en) | 1990-06-22 | 1992-08-18 | Tas, Inc. | Fluidized calcining process |
JPH06505486A (ja) | 1991-02-07 | 1994-06-23 | モレキュメティクス,リミティド | βターンおよびβバルジのコンフォメーション的に制限された模倣物およびそれらを含有するペプチド |
NZ241954A (en) | 1991-03-15 | 1994-01-26 | Amgen Inc | Compositions of g-csf for pulmonary administration. |
NZ299249A (en) | 1992-09-24 | 2000-08-25 | Brigham & Womens Hospital | Use of an antigenic conjugate of a capsular polysaccharide from streptococcus and a protein component to immunise neonates |
ZA937034B (en) | 1992-09-24 | 1995-06-23 | Brigham & Womens Hospital | Group B streptococcus type II and type V polysaccharide-protein conjugate vaccines |
DK1310510T3 (da) | 1993-05-27 | 2007-09-24 | Aventis Pharma Inc | Topologisk adsilte, kodede biblioteker med fast fase |
US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
EP0942982A1 (en) | 1996-02-29 | 1999-09-22 | Washington University | Bacterial elastin binding protein, nucleic acid sequence encoding same and diagnostic and therapeutic methods of use thereof |
US6448043B1 (en) | 1997-05-06 | 2002-09-10 | Human Genome Sciences, Inc. | Enterococcus faecalis EF040 and uses therefor |
JP2002531055A (ja) | 1998-07-27 | 2002-09-24 | マイクロビアル テクニクス リミティッド | 肺炎連鎖球菌のタンパク質及び核酸分子 |
JP2002531054A (ja) | 1998-07-27 | 2002-09-24 | マイクロビアル テクニクス リミティッド | B群連鎖球菌由来の核酸およびタンパク質 |
WO2000012132A1 (en) | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
CA2365523A1 (en) | 1999-04-15 | 2000-10-26 | The Regents Of The University Of California | Identification of sortase gene |
AU5755500A (en) | 1999-06-21 | 2001-01-09 | University Of Utah Research Foundation | Isolated genes from virulent group B streptococcus agalactiae |
US9002545B2 (en) | 2011-01-07 | 2015-04-07 | Wabtec Holding Corp. | Data improvement system and method |
-
2001
- 2001-08-08 WO PCT/US2001/024795 patent/WO2002012294A2/en active IP Right Grant
- 2001-08-08 DE DE60128115T patent/DE60128115T2/de not_active Expired - Lifetime
- 2001-08-08 ES ES01959633T patent/ES2286133T3/es not_active Expired - Lifetime
- 2001-08-08 AT AT01959633T patent/ATE360640T1/de active
- 2001-08-08 EP EP01959633A patent/EP1320542B9/en not_active Expired - Lifetime
- 2001-08-08 AU AU2001281168A patent/AU2001281168A1/en not_active Abandoned
- 2001-08-08 US US10/333,002 patent/US7128919B2/en not_active Expired - Fee Related
- 2001-08-08 PT PT01959633T patent/PT1320542E/pt unknown
- 2001-08-08 DK DK01959633T patent/DK1320542T3/da active
- 2001-08-08 CA CA002417357A patent/CA2417357A1/en not_active Abandoned
- 2001-08-08 EP EP07002407A patent/EP1810978B1/en not_active Expired - Lifetime
-
2006
- 2006-07-26 US US11/493,705 patent/US7645577B2/en not_active Expired - Fee Related
-
2007
- 2007-07-19 CY CY20071100967T patent/CY1107702T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1810978A3 (en) | 2007-10-24 |
AU2001281168A1 (en) | 2002-02-18 |
DE60128115T2 (de) | 2008-03-06 |
EP1810978B1 (en) | 2013-02-13 |
US7128919B2 (en) | 2006-10-31 |
EP1810978A2 (en) | 2007-07-25 |
EP1320542B9 (en) | 2007-09-12 |
PT1320542E (pt) | 2007-08-06 |
US7645577B2 (en) | 2010-01-12 |
ES2286133T3 (es) | 2007-12-01 |
WO2002012294A2 (en) | 2002-02-14 |
CA2417357A1 (en) | 2002-02-14 |
DE60128115D1 (de) | 2007-06-06 |
EP1320542A2 (en) | 2003-06-25 |
WO2002012294A3 (en) | 2003-04-10 |
US20040071729A1 (en) | 2004-04-15 |
CY1107702T1 (el) | 2013-04-18 |
EP1320542B1 (en) | 2007-04-25 |
ATE360640T1 (de) | 2007-05-15 |
US20070178116A1 (en) | 2007-08-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1320542T3 (da) | Gruppe B streptokokpolypeptider-nukleinsyrer og terapeutiske sammensætninger og vacciner deraf | |
IL264925A (en) | Isolated or recombinant proteins that induce an immune response against S. PYOGENES, preparations containing them and their uses | |
EP3167900B1 (en) | Vaccine against streptococci | |
WO2002083855A3 (en) | Novel streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof | |
AR003124A1 (es) | Proteinas estreptococicas de shock termico miembros de la familia de hsp7270,secuencia de adn que codifica para dichos polipeptidos, vector deexpresion, molecula de adn recombinante, metodo para producir un polipeptido o fragmento del mismo, anticuerpo o fragmento del mismo y anticuerpo monoclonal, | |
NZ551802A (en) | A hyperimmune serum-reactive antigen consisting of a polypeptide comprising an amino acid sequence in SEQ ID NO:422 and antigenic fragments thereof | |
HUP0500459A2 (hu) | Streptococcus suis vakcinák és diagnosztikai tesztek | |
NO20070618L (no) | Forbindelser og fremgangsmater for immunterapi og diagnose av tuberkulose. | |
EA007409B1 (ru) | Антигенные полипептиды стрептококков, способы их получения и применения | |
KR20070101197A (ko) | 유전자와 단백질들, 및 그들의 사용 | |
JP2009542196A (ja) | 小型の化膿連鎖球菌抗原およびそれらの使用 | |
WO2002050277A3 (en) | Protein and nucleic acids encoding same | |
HUP0100267A2 (hu) | Helicobacter pylori eredetű nukleinsav- és aminosav-szekvenciák és a megfelelő nukleinsavakat vagy peptideket tartalmazó vakcina-készítmények | |
Cullen et al. | Construction and evaluation of a plasmid vector for the expression of recombinant lipoproteins in Escherichia coli | |
WO2004020609A3 (en) | Streptococcus pneumoniae antigens for diagnosis, treatment and prevention of active infection | |
BR9908476A (pt) | Peptìdeo, composição terapêutica, e, processo para conferir imunidade protetora a um paciente, contra a infecção de s. pneumoniae | |
CA2718473A1 (en) | Peptides protective against s. pneumoniae and compositions, methods and uses relating thereto | |
Chessa et al. | Genetic immunization with the immunodominant antigen P48 of Mycoplasma agalactiae stimulates a mixed adaptive immune response in BALBc mice | |
DE60035485D1 (de) | IDENTIFIZIERUNG VON SPEZIFISCHEN DIFFERENZIELL EXPRIMIERTEN ANTIGENEN AUS MYCOBACTERIUM UND MEDIZINISCHE VERWENDUNG DER MYCOBAKTERIUMPROTEINE Rv0068 UND Rv3407 | |
EP2450053B1 (en) | Novel antigen of enterococcal pathogens and use thereof as vaccine component for therapy and/or prophylaxis | |
KR20080052693A (ko) | 유전자, 단백질 및 그들의 용도 | |
WO2002050276A3 (en) | Proteins and nucleic acids encoding same | |
HUP0200832A2 (hu) | Babesia canis oltóanyag | |
NZ512448A (en) | Chlamydia antigens and corresponding DNA fragments and uses thereof | |
NZ311874A (en) | Recombinant and/or pure preparations of H. pylori polypeptides and nucleic acids which are useful for diagnostics and vaccines |